| structural basis for antiviral inhibition of the main protease 3c from human enterovirus 93. | the enteroviruses genus of the picornaviridae family is abundant with common human pathogens that belong to rhinoviruses (hrvs) and enteroviruses (evs), including diverse echo-, coxsackie- and polio- viruses. they cause a wide spectrum of clinical manifestations ranging from asymptomatic to severe diseases with neurological and/or cardiac manifestations. pandemic outbreaks of evs may be accompanied with meningitis and/or paralysis and can be fatal. however, there is no effective prophylaxis or a ... | 2011 | 21835784 |
| detection and characterization of enteroviruses and parechoviruses in healthy people living in the south of côte d'ivoire. | human enteroviruses (evs) and parechoviruses (hpevs) belong to the family picornaviridae. although most ev and hpev infections remain asymptomatic, both pathogens can cause a wide spectrum of clinical manifestations ranging from respiratory or gastrointestinal symptoms to myocarditis, neonatal sepsis, and infections of the central nervous system. | 2015 | 26370313 |
| complete coding regions of the prototypes enterovirus b93 and c95: phylogenetic analyses of the p1 and p3 regions of ev-b and ev-c strains. | complete coding regions were sequenced for two new enterovirus genomes: ev-b93 previously identified by vp1 sequencing, derived from a child with acute flaccid paralysis in the democratic republic of congo; and ev-c95 from a french soldier with acute gastroenteritis in djibouti. the ev-b93 p1 had more than 30% nucleotide divergence from other ev-b types, with highest similarity to e-15 and ev-b80. the p1 nucleotide sequence of ev-c95 was most similar, 71%, to cv-a21. complete coding regions for ... | 2015 | 25163640 |