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complete genome sequence of bovine viral diarrhea virus-1 strain egy/ismailia/2014, subtype 1b.here, we report the complete genome sequence of bovine viral diarrhea virus-1b (bvdv-1b), strain egy/ismailia/2014. the virus genome is composed of 12,217 nucleotides organized as one open reading frame encoding 3,898 amino acids. this report will assist efforts in diagnostics, studying molecular epidemiology, and control of bvdv in egypt.201526701085
predominance of bovine viral diarrhea virus 1b and 1d subtypes during eight years of survey in poland.the genetic diversity of bovine viral diarrhea virus (bvdv) was determined from 65 animals persistently infected with bvdv and diagnosed between 2004 and 2011 in poland. the samples originated from 28 herds in 12 provinces, where over 90% of the whole cattle population of poland is reared. phylogenetic analysis based on the fragments of two genomic regions of bvdv namely, 5'-untranslated region (5'-utr) and n(pro) was performed. all the bvdv isolates belonged to bvdv-1 species and were further d ...201323890673
immunogenicity of an inactivated chinese bovine viral diarrhea virus 1a (bvdv 1a) vaccine cross protects from bvdv 1b infection in young calves.bovine viral diarrhea virus (bvdv) 1a and 1b strains are the predominant subgenotypes in china. because of the genetic and antigenic variability among different bvdv strains, a vaccine effective in one region may fail to protect against infections caused by different virus strains in another region. no bvdv vaccine developed with the predominant strains in china are available. in this study, the immunogenicity of an inactivated chinese bvdv 1a nm01 vaccine strain was evaluated by challenging wit ...201424880701
effect of copper, manganese, and zinc supplementation on the performance, clinical signs, and mineral status of calves following exposure to bovine viral diarrhea virus type 1b and subsequent infection.research has indicated that trace mineral (tm) supplementation may alter immune function and reduce morbidity associated with bovine respiratory disease. the objective of this experiment was to determine the influence of dietary cu, mn, and zn supplementation on the performance, clinical signs, and tm balance of calves following a bovine viral diarrhea virus (bvdv) and (mh) combination respiratory pathogen challenge. steers ( = 16; 225 ± 20 kg bw) from a single ranch were processed, weaned, and ...201627065274
effect of timing of challenge following short-term natural exposure to bovine viral diarrhea virus type 1b on animal performance and immune response in beef steers.bovine respiratory disease (brd) is the most common and economically detrimental disease of beef cattle during the postweaning period, causing the majority of morbidity and mortality in feedlots. the pathogenesis of this disease often includes an initial viral infection, which can predispose cattle to a secondary bacterial infection. the objective of this experiment was to determine the effects of timing of an intratracheal (mh) challenge relative to 72 h of natural exposure to bovine viral diar ...201627898956
transmission of bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves.bovine viral diarrhea virus (bvdv) persistently infected (pi) calves represent significant sources of infection to susceptible cattle. the objectives of this study were to determine if pi calves transmitted infection to vaccinated and unvaccinated calves, to determine if bvdv vaccine strains could be differentiated from the pi field strains by subtyping molecular techniques, and if there were different rates of recovery from peripheral blood leukocytes (pbl) versus serums for acutely infected ca ...200516187545
effects of exposure to calves persistently infected with bovine viral diarrhea virus type 1b and mannheimia haemolytica challenge on animal performance, nitrogen balance, and visceral organ mass in beef steers.bovine viral diarrhea viruses (bvdv) have been isolated alone or in combination with other viral and bacterial pathogens in animals diagnosed with bovine respiratory disease (brd), a disease causing major economic loss to the feedlot industry. the objective of this experiment was to determine the effects of mannheimia haemolytica challenge after short-term exposure (72 h) to bovine viral diarrhea virus type 1b (bvdv1b) persistently infected (pi) calves on performance, n balance, and organ mass i ...201020154160
effects of exposure to calves persistently infected with bovine viral diarrhea virus type 1b and subsequent infection with mannheima haemolytica on clinical signs and immune variables: model for bovine respiratory disease via viral and bacterial interaction.the objective was to determine effects of an intratracheal mannheimia haemolytica challenge after 72-h exposure to bovine viral diarrhea virus type 1b (bvdv1b) persistently infected (pi) calves on serum antibody production, white blood cell count (wbc), cytokine concentrations, and blood gases in feedlot steers. twenty-four steers (initial bw = 314 +/- 31 kg) were randomly allocated to 1 of 4 treatments (6 steers/treatment) arranged as a 2 x 2 factorial. treatments were 1) steers not exposed to ...201020154164
the effects of exposure of susceptible alpacas to alpacas persistently infected with bovine viral diarrhea virus.reports of bovine viral diarrhea virus (bvdv) infections in alpacas have been increasing in recent years but much is still unknown about the mechanisms of disease in this species. this report characterizes the transmission of bvdv from persistently infected (pi) alpacas to bvdv naïve alpacas, documents shedding patterns, and characterizes the disease effects in both pi and transiently infected alpacas. two pi alpacas shed bvdv type 1b virus in most body fluids, and commonly available diagnostic ...201121629418
pathogenicity of an indian isolate of bovine viral diarrhea virus 1b in experimentally infected calves.the aim of this study was to determine the pathogenicity of an indian bovine viral diarrhea virus (bvdv) 1b isolate in 7-9-months-old male calves. infected (four) and control (two) calves were bled at three days interval for hematological, virological and serological studies until day 27. all infected calves developed respiratory illness, biphasic pyrexia, mild diarrhea, leucopenia and mild thrombocytopenia. viraemia was demonstrated between 3 and 15dpi and the infected calves seroconverted by 1 ...200717383693
experimental infection of korean native goats (capra aegagrus hircus) with bovine viral diarrhea virus 1b.bovine viral diarrhea virus (bvdv) infects various ungulates and causes reproductive failure in infected goats. bvdv has been detected among goats in the republic of korea, but the route of transmission remains unclear. here, we aimed to investigate whether bvdv-1b circulating among korean cattle can be transmitted to korean native goats (capra aegagrus hircus) and characterize the outcomes of bvdv infection in these goats.201931200717
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