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clinical infection of two captive asian elephants (elephas maximus) with elephant endotheliotropic herpesvirus 1b.the ability of prior infection from one elephant endotheliotropic herpesvirus (eehv) type to protect against clinical or lethal infection from others remains an important question. this report describes viremia and subsequent shedding of eehv1b in two juvenile 4-yr-old asian elephants within 3 wk or 2 mo following significant infections caused by the rarely seen eehv4. high levels of eehv1b shedding were detected in the first elephant prior to emergence of infection and viremia in the second ani ...201627010294
using in-house hematology to direct decision-making in the successful treatment and monitoring of a clinical and subsequently subclinical case of elephant endotheliotropic herpesvirus 1b.a 3.5-yr-old asymptomatic female asian elephant (elephas maximus) with a high load of circulating eehv1b dna on qpcr on a routine blood sample, showed progressive depletion of monocytes, lymphocytes, and platelets. twice daily iv ganciclovir, plasma transfusions, and fluid therapy coincided with a decreasing viral load, which may support potential efficacy of this antiviral drug. an increase in lymphocytes followed initial treatment and preceded the onset of clinical signs. administration of sho ...201931260223
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