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the rna profile of porcine parvovirus 4, a boca-like virus, is unique among the parvoviruses.ppv4 transcribes its genome from a single promoter, and the rnas are generated via alternate splicing coupled with alternate polyadenylation, a strategy similar to that of the bocaviruses; however, several differences were detected. the ppv4 orf1 codes for four ns proteins, while the bocavirus orf1 codes for 1-3 ns proteins. whereas the vp1/vp2 capsid proteins of bocavirus are encoded by a single rna, vp1 and vp2 of ppv4 are encoded by two separate rnas. while orf3 of ppv4 encodes two np protein ...201121785854
porcine bocaviruses: genetic analysis and prevalence in chinese swine population.summaryin members of the bocavirus genus, that contain three open reading frames (orfs) of the parvovirinae subfamily, porcine bocaviruses (pobovs) exhibit the most genetic diversity. based on the orf2-encoded viral protein (vp1) classification, the six reported porcine bocaviruses were grouped into four species: pobov1 (porcine boca-like virus or pbolv), pobov2 (porcine parvovirus 4 or ppv4), pobov3 (pbov1/pbov2) and pobov4 (6v/7v), with pobov3 and pobov4 each having two genotype viruses. all f ...201121676363
identification and genomic characterization of a novel porcine parvovirus (ppv6) in china.parvoviruses are classified into two subfamilies based on their host range: the parvovirinae, which infect vertebrates, and the densovirinae, which mainly infect insects and other arthropods. in recent years, a number of novel parvoviruses belonging to the subfamily parvovirinae have been identified from various animal species and humans, including human parvovirus 4 (parv4), porcine hokovirus, ovine partetravirus, porcine parvovirus 4 (ppv4), and porcine parvovirus 5 (ppv5).201425442288
viral metagenomic analysis of bushpigs (potamochoerus larvatus) in uganda identifies novel variants of porcine parvovirus 4 and torque teno sus virus 1 and 2.as a result of rapidly growing human populations, intensification of livestock production and increasing exploitation of wildlife habitats for animal agriculture, the interface between wildlife, livestock and humans is expanding, with potential impacts on both domestic animal and human health. wild animals serve as reservoirs for many viruses, which may occasionally result in novel infections of domestic animals and/or the human population. given this background, we used metagenomics to investig ...201222967311
a taqman-based real-time pcr for detection and quantification of porcine parvovirus 4.porcine parvovirus 4 (ppv4) is a dna virus, and a member of the parvoviridae family within the bocavirus genera. it was detected recently in swine, but its epidemiology and pathology remain unclear. a taqman-based real-time pcr (qpcr) targeting a conserved region of the orf3 gene of ppv4 was developed. the qpcr detection limit was 9.5 × 10(1) dna copies/μl. there was no cross-reaction with porcine parvovirus, torque teno virus 1, torque teno virus 2, porcine circovirus type 1, porcine circovirus ...201525813599
ungulate copiparvovirus 2 in healthy and postweaning multisystemic wasting syndrome-affected pigs.a sybr green-based real-time polymerase chain reaction (qpcr) was designed to detect ungulate copiparvovirus 2, also known as porcine parvovirus 4 (ppv4). the test was applied to search for ppv4 dnaemia in sera from 1- to 4-month-old pigs displaying signs of postweaning multisystemic wasting syndrome (pmws), as well as in sera from healthy swine at equivalent age and in sera from older healthy animals (>6 months old). high levels of ppv4 dna were detected in pmws-affected pigs. the mean viral dn ...201728382380
porcine hokovirus in wild boar in portugal.porcine hokovirus (phov), also referred to as porcine parvovirus 4 (p-parv4), a recently discovered parvovirus of swine that is closely related to human parvovirus 4/5 (h-parv4/5), was first described in hong kong. to evaluate the occurrence of p-parv4 in portuguese wild boars in the hunting season of 2011/2012, liver and serum samples were tested. p-parv4 was detected in 24 % of the wild boars analyzed. phylogenetic analysis showed a close relationship between the p-parv4 isolates and other p-p ...201626711454
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