| the pathogenesis and pathology of experimental quaranfil virus infection. | mice were infected intranasally with quaranfil arbovirus, and killed at intervals from 1 day to 2 months later. the infection produced clinical signs of neurological disturbance and a highly mortality. the virus could be isolated from the lungs on days 1-9 and from the brain on days 1-11 of the infection. meningoencephalitis developed by day 5 in the olfactory lobes and spread progressively caudally, involving all regions of the brain by day 7. the prinicipal features of the inflammatory process ... | 1976 | 1268046 |
| influence of feeding and starvation on the persistence and transmission of quaranfil virus by argas (persicargas) arboreus (acari: argasidae). | viral antigen was detected in the cytoplasm and in associated membranes of salivary gland acinus cells by indirect immunofluorescence and immunoperoxidase staining. viral ribonucleoproteins (indicated histochemically by presence of pyroninophilic granules) which had accumulated in the cytoplasm of salivary gland type b (granular) acini of unfed argas (persicargas) arboreus kaiser, hoogstraal & kohls were no longer visible 24 h after feeding. virus in tick salivary glands increased from 300 to 50 ... | 1990 | 2388240 |
| electron microscopy and antigenic studies of uncharacterized viruses. i. evidence suggesting the placement of viruses in families arenaviridae, paramyxoviridae, or poxviridae. | during approximately 35 years, investigators in various laboratories studying arbovirus ecology and epidemiology accumulated many virus isolates, more than 60 of which were not characterized or placed in taxa. by a combination of electron microscopic and antigenic studies we collected information sufficient to provisionally classify 60 isolates. electron microscopic observations suggest that 20 are members of the virus family bunyaviridae, 20 rhabdoviridae, 14 reoviridae, one togaviridae, one pa ... | 1989 | 2690775 |
| viruses in ticks. ii. experimental transmission of quaranfil virus by argas (persicargas) arboreus and a. (p.) persicus. | | 1966 | 5959112 |
| histochemical observations on the effect of quaranfil virus on the salivary glands of argas (persicargas) arboreus (ixodoidea: argasidae). | | 1984 | 6512304 |
| quaranfil virus in infected argas (persicargas) arboreus salivary glands. | | 1982 | 6759588 |
| quaranfil virus in experimentally infected argas (persicargas) arboreus and a. (p.) persicus (ixodoidea: argasidae) during wintertime in egypt: effect of natural and controlled conditions of temperature and relative humidity. | | 1982 | 7072466 |
| quaranfil virus from hyalomma dromedarii (acari: ixodoidea) collected in kuwait, iraq and yemen. | | 1982 | 7086857 |
| [arbovirus infections in morocco: serosurvey in small wild mammals in the northern part of the country]. | sera of 128 small wild mammals (rodents, insectivora) trapped in northern morocco in march 1979, were studied for antibody against 15 arboviruses. in inhibition-haemagglutination tests, positive reactions were found against west nile (0.8%), tahyna (21 %), arumowot (14 %) and sicilian sandfly fever (9.4 %) viruses. in complement fixation tests, an unique serum from apodemus sylvaticus was simultaneously positive for quaranfil virus and for a kemerovo group virus, brest/ar/t222, previously isolat ... | 1982 | 7165896 |
| experimental immunosuppression and infection of chickens with quaranfil virus. | in ovo hormonal bursectomy of chick embryos was carried out by chorioallantoic membrane inoculation with testosterone propionate at the 18th day of embryonation. at hatching immunosuppression was complemented with sublethal x-irradiation. at 40 days of age the immunomanipulated and control chickens were inoculated subcutaneously with a single dose of quaranfil virus. it was observed that bursectomy and bursectomy with sublethal x-irradiation prolonged viraemia up to the 20th day following virus ... | 1984 | 18766886 |
| quaranfil, johnston atoll, and lake chad viruses are novel members of the family orthomyxoviridae. | arboviral infections are an important cause of emerging infections due to the movements of humans, animals, and hematophagous arthropods. quaranfil virus (qrfv) is an unclassified arbovirus originally isolated from children with mild febrile illness in quaranfil, egypt, in 1953. it has subsequently been isolated in multiple geographic areas from ticks and birds. we used high-throughput sequencing to classify qrfv as a novel orthomyxovirus. the genome of this virus is comprised of multiple rna se ... | 2009 | 19726499 |
| cyclic avian mass mortality in the northeastern united states is associated with a novel orthomyxovirus. | since 1998, cyclic mortality events in common eiders (somateria mollissima), numbering in the hundreds to thousands of dead birds, have been documented along the coast of cape cod, ma, usa. although longitudinal disease investigations have uncovered potential contributing factors responsible for these outbreaks, detecting a primary etiological agent has proven enigmatic. here, we identify a novel orthomyxovirus, tentatively named wellfleet bay virus (wfbv), as a potential causative agent of thes ... | 2014 | 25392223 |
| comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains. | orthomyxovirus influenza a virus (iav) heterotrimeric polymerase performs transcription of viral mrnas by cap-snatching, which involves generation of capped primers by host pre-mrna binding via the pb2 subunit cap-binding site and cleavage 10-13 nucleotides from the 5' cap by the pa subunit endonuclease. thogotoviruses, tick-borne orthomyxoviruses that includes thogoto (thov), dhori (dhov) and jos (josv) viruses, are thought to perform cap-snatching by cleaving directly after the cap and thus ha ... | 2014 | 24454773 |
| [taxonomic status of the tyulek virus (tlkv) (orthomyxoviridae, quaranjavirus, quaranfil group) isolated from the ticks argas vulgaris filippova, 1961 (argasidae) from the birds burrow nest biotopes in the kyrgyzstan]. | the tyulek virus (tlkv) was isolated from the ticks argas vulgaris filippova, 1961 (argasidae), collected from the burrow biotopes in multispecies birds colony in the aksu river floodplain near tyulek village (northern part of chu valley, kyrgyzstan). recently, the tlkv was assigned to the quaranfil group (including the quaranfil virus (qrfv), johnston atoll virus (jav), lake chad virus) that is a novel genus of the quaranjavirus in the orthomyxoviridae family. in his work, the complete genome ( ... | 2016 | 25069282 |