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clinical and radiological features of pulmonary disease caused by rapidly growing mycobacteria in cancer patients.the role of rapidly growing mycobacteria in the pathogenesis of pulmonary disease is being increasingly recognized; however, the clinical significance of these mycobacteria in patients with underlying malignancy has not been well studied. over a 6-year period, 37 cancer patients with rapidly growing mycobacteria isolated from respiratory specimens were identified at our center. mycobacterium chelonae group was isolated in 24 cases and mycobacterium fortuitum in 13 cases. of the 24 cases with cul ...19989832262
mycobacterium immunogenum sp. nov., a novel species related to mycobacterium abscessus and associated with clinical disease, pseudo-outbreaks and contaminated metalworking fluids: an international cooperative study on mycobacterial taxonomy.pcr-restriction enzyme pattern analysis of a 439 bp hsp65 gene segment identified 113 unique isolates among non-pigmented rapidly growing mycobacteria (rgm) from clinical and environmental sources that failed to match currently recognized species patterns. this group represented 40% of isolates recovered from bronchoscope contamination pseudo-outbreaks, 0% of disease-associated nosocomial outbreaks and 4% of routine clinical isolates of the mycobacterium abscessus/mycobacterium chelonae group su ...200111594606
an outbreak of hypersensitivity pneumonitis at a metalworking plant: a longitudinal assessment of intervention effectiveness.the authors describe a longitudinal assessment of intervention effectiveness in response to an outbreak of hypersensitivity pneumonitis (hp) at a metalworking facility. thirty-five (29%) of the plant's 120 production workers were given a clinical diagnosis of hp during the two years of the investigation. although quantitative exposure assessment tools were of limited utility, the investigators successfully used qualitative observations and the patients' return-to-work experiences to iteratively ...200312519684
antimicrobial resistance of rapidly growing mycobacteria in western taiwan: smart program 2002.to understand the resistance patterns of rapidly growing mycobacteria (rgm) in taiwan, antimicrobial resistance of clinical isolates was determined as part of the smart (surveillance from multicenter antimicrobial resistance in taiwan) program.200818445541
identification of non-tuberculous mycobacteria by real-time pcr coupled with a high-resolution melting system.non-tuberculous mycobacteria (ntm) are increasingly important opportunistic pathogens responsible for a variety of clinical diseases. the aim of this study was to evaluate a novel technique, real-time pcr coupled with high-resolution melting analysis (real-time pcr-hrma), for ntm identification. two pairs of unique primers targeted to the 16s rrna gene and the 16s-23s internal transcribed spacer region were selected for further evaluation. a total of 149 mycobacterial clinical isolates were subj ...201222493281
whole-genome sequences of four strains closely related to members of the mycobacterium chelonae group, isolated from biofilms in a drinking water distribution system simulator.we report here the draft genome sequences of four mycobacterium chelonae strains from biofilms subjected to a "chlorine burn" in a chloraminated drinking water distribution system simulator. these opportunistic pathogens have been detected in hospital and municipal water distribution systems, in which biofilms have been recognized as an important factor for their persistence.201626798093
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