| hypoxia affects cellular responses to plant extracts. | microenvironmental conditions contribute towards varying cellular responses to plant extract treatments. hypoxic cancer cells are known to be resistant to radio- and chemo-therapy. new therapeutic strategies specifically targeting these cells are needed. plant extracts used in traditional chinese medicine (tcm) can offer promising candidates. despite their widespread usage, information on their effects in hypoxic conditions is still lacking. in this study, we examined the cytotoxicity of a serie ... | 2012 | 23022321 |
| effects of dietary supplementation with gynura procumbens (merr.) on egg yolk cholesterol, excreta microflora and laying hen performance. | abstract 1. the present study investigated the effects of dietary supplementation with gynura procumbens on egg yolk and serum cholesterol and triglycerides, excreta microflora, laying performance and egg quality. 2. a total of 160 hy-line brown layers (45 weeks old) were randomly assigned into 4 treatments on the basis of laying performance. each treatment had 4 replicates with 10 birds each. 3. dietary treatments were basal diet supplemented with 0 (control), 2.5, 5.0 and 7.5 g/kg diet g. proc ... | 2014 | 25010164 |
| antiherpetic effects of gynura procumbens. | the ethanol extract of gynura procumbens showed virucidal and antireplicative actions against herpes simplex virus hsv-1 and hsv-2. it was further chromatographed on mci gel chp20p column giving the extract fractions f1 (water), f2 (water-methanol) f3 (methanol), and f4 (ethyl acetate). all but f1 had virucidal action against both viral types. we reported here the active compounds from f2 and f3. the antiherpetic compounds of f2 was a mixture of dicaffeoylquinic acids with virucidal and antirepl ... | 2013 | 24159345 |
| rice cakes containing dietary fiber supplemented with or without artemisia annua and gynura procumbens merr. alleviated the risk factors of metabolic syndrome. | we investigated whether the consumption of korean rice cakes enriched with dietary fiber with or without polyphenol rich plants might decrease the risk factors of metabolic syndrome (mets). rice cakes were manufactured using fructooligosaccharides, resistant starch, and psyllium as sources of dietary fibers with and without polyphenol rich artemisia annua and gynura procumbens merr. (rc+fp and rc+f, respectively), and prepared in three forms (songpyeon, seolgidduk, and chaldduk). ninety subjects ... | 2016 | 27152297 |
| gynura procumbens merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels. | gynura procumbens has been shown to decrease blood pressure via inhibition of the angiotensinconverting enzyme. however, other mechanisms that may contribute to the hypotensive effect have not been studied. | 2011 | 21437451 |
| hypoglycemic effect of combination of azadirachta indica a. juss. and gynura procumbens (lour.) merr. ethanolic extracts standardized by rutin and quercetin in alloxan-induced hyperglycemic rats. | exploration of plant combinations could be an alternative approach for diabetes treatment. the aim of this study is to evaluate the hypoglycemic effect of combination of a. indica and g. procumbens ethanolic extracts in alloxan-induced diabetic rats. | 2014 | 25671197 |
| effect of probiotic bacteria-fermented medicinal plants (gynura procumbens, rehmannia glutinosa, scutellaria baicalensis) as performance enhancers in growing pigs. | this study was conducted to investigate the effect of dietary supplementation of mixed fermented medicinal plants (fmp) obtained from exudates of gynura procumbens, rehmannia glutinosa and scutellaria baicalensis fermented with lactobacillus plantarum, saccharomyces cerevisiae and bacillus licheniformis, respectively, on growth performance in growing pigs in order to assess the feasibility of using fmp as an alternative to antibiotic growth promoters (agp), such as tiamulin. a total of 150 growi ... | 2015 | 25523719 |
| inhibition effect of gynura procumbens extract on uv-b-induced matrix-metalloproteinase expression in human dermal fibroblasts. | gynura procumbens merr. (asteraceae) has been used as a traditional remedy for various skin diseases in certain areas of southeast asia. | 2011 | 21672616 |
| screening of endophytic bacteria isolated from leaves of sambung nyawa [gynura procumbens (lour.) merr.] for cytokinin-like compounds. | endophytic bacteria are harmless in most plant species; and known to boost the growth and development of the host plants probably by secreting growth hormones. the isolation, identification and screening of endophytic bacteria for the plant growth regulators like cytokinin are needed to get the leads for their applications in agriculture sector. we describe the isolation and identification of the bacterial endophytes from the leaves of sambung nyawa [gynura procumbens (lour.) merr.] and their sc ... | 2010 | 21364796 |
| toxicology evaluation of standardized methanol extract of gynura procumbens. | gynura procumbens (merr.), which is known as "sambung nyawa", is widely used in south east asian countries in the traditional treatment of many ailments. however, there is little toxicological information available regarding safety following repeated exposure. the present investigation describes the toxicity of a methanol extract of gynura procumbens leaves in rats. | 2009 | 19429368 |
| antiinflammatory screening of the medicinal plant gynura procumbens. | gynura procumbens is used in thai folk medicine to treat topical inflammation, rheumatism, and viral ailments. in the present work, attempts were made to verify the folk medicinal claim that the crude ethanolic extract of g. procumbens has antiinflammatory action and to relate the activity to particular fractions using a croton oil-induced mouse ear inflammation model. the original ethanolic extract of g. procumbens was partitioned between water and ethyl acetate. the residues were subjected to ... | 2002 | 12602932 |
| effects of an ethanolic extract of gynura procumbens on serum glucose, cholesterol and triglyceride levels in normal and streptozotocin-induced diabetic rats. | the aim was to demonstrate the effects of the leaves of gynura procumbens (lour.) merr. on blood sugar and lipid levels in experimental animals. | 2000 | 10783673 |
| antidiabetic properties and mechanism of action of gynura procumbens water extract in streptozotocin-induced diabetic rats. | gynura procumbens (lour.) merr (family compositae) is cultivated in southeast asia, especially indonesia, malaysia and thailand, for medicinal purposes. this study evaluated the in vivo hypoglycemic properties of the water extract of g. procumbens following 14 days of treatment and in vitro in rin-5f cells. glucose absorption from the intestines and its glucose uptake in abdominal skeletal muscle were assessed. the antidiabetic effect of water extract of g. procumbens leaves was investigated in ... | 2010 | 21150821 |
| inhibition of angiotensin-converting enzyme activity by a partially purified fraction of gynura procumbens in spontaneously hypertensive rats. | to investigate the hypotensive and angiotensin-converting enzyme (ace) inhibitory activities of a partially purified fraction (fa-i) of the leaves of gynura procumbens and to qualitatively analyse the putative compounds present in the fraction. | 2007 | 17409755 |
| antihypertensive effects of gynura procumbens extract in spontaneously hypertensive rats. | aqueous extracts of gynura procumbens (lour.) merr. were orally administered to spontaneously hypertensive (shr) rats for 4 weeks, and antihypertensive effects were determined. oral administration of 500 mg/kg of g. procumbens (lour.) merr. extract (gpe) resulted in significantly lower blood pressure in shr rats compared with shr rats not given gpe (p < .05). furthermore, gpe-administered rats had significantly lower serum lactate dehydrogenase, creatine phosphate kinase, and increased nitric ox ... | 2006 | 17201650 |