| natural and experimental infection of turkeys with avian paramyxovirus-7. | avian paramyxovirus-7 was isolated from a natural outbreak of respiratory tract disease in male and female commercial turkey breeder flocks. the disease spread readily between different housing complexes. the virus was isolated from affected flocks and used for experimental studies in specific-pathogen-free poults. inoculated and contact-exposed poults developed a respiratory disease characterized by rhinitis and airsacculitis. the virus was isolated from the inoculated and contact-exposed poult ... | 1997 | 9201395 |
| complete genome sequence of avian paramyxovirus type 7 (strain tennessee) and comparison with other paramyxoviruses. | the complete genome sequence of avian paramyxovirus serotype 7 (apmv-7) prototype strain dove/tennessee/4/75 was determined. the genome size is 15,480 nucleotides (nt) long and follows the "rule of six". the genome contains six non-overlapping genes in the order of 3'-n-p/v/w-m-f-hn-l-5'. the 3'-leader and 5'-trailer sequences of the genome are 55 and 127nt long, respectively. the first 12nt of the leader and trailer sequences are complementary to each other. the viral genes are flanked by highl ... | 2009 | 19540277 |
| mutation of the f protein cleavage site of avian paramyxovirus-7 results in furin cleavage, fusion promotion and increased replication in vitro, but not increased replication, tissue tropism, or virulence in chickens. | we constructed a reverse genetics system for avian paramyxovirus serotype 7 (apmv-7) to investigate the role of the fusion f glycoprotein in tissue tropism and virulence. the ampv-7 f protein has a single basic residue arginine (r) at position -1 in the f cleavage site sequence and also is unusual in having alanine at position +2 (lpssr↓fa) (underlining indicates the basic amino acids at the f protein cleavage site, and the arrow indicates the site of cleavage.). apmv-7 does not form syncytia or ... | 2012 | 22258248 |