Publications

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a longitudinal assessment of changes in bacterial community composition associated with the development of periodontal disease in dogs.periodontal disease is the most widespread oral disease in dogs. whilst the involvement of bacteria in the aetiology of periodontitis is well established the role of individual species and their complex interactions with the host is not well understood. the objective of this research was therefore to perform a longitudinal study in dogs to identify the changes that occur in subgingival bacterial communities during the transition from mild gingivitis to the early stages of periodontitis (<25% att ...201526507828
early canine plaque biofilms: characterization of key bacterial interactions involved in initial colonization of enamel.periodontal disease (pd) is a significant problem in dogs affecting between 44% and 63.6% of the population. the main etiological agent for pd is plaque, a microbial biofilm that colonizes teeth and causes inflammation of the gingiva. understanding how this biofilm initiates on the tooth surface is of central importance in developing interventions against pd. although the stages of plaque development on human teeth have been well characterized little is known about how canine plaque develops. re ...201425463050
comparison of the oral microbiomes of canines and their owners using next-generation sequencing.the oral microbiome, which is closely associated with many diseases, and the resident pathogenic oral bacteria, which can be transferred by close physical contact, are important public health considerations. although the dog is the most common companion animal, the composition of the canine oral microbiome, which may include human pathogenic bacteria, and its relationship with that of their owners are unclear. in this study, 16s rdna pyrosequencing was used to compare the oral microbiomes of 10 ...201526134411
neisseria wadsworthii sp. nov. and neisseria shayeganii sp. nov., isolated from clinical specimens.an analysis of 16s rrna gene sequences from archived clinical reference specimens has identified two novel neisseria species. for each species, two strains from independent sources were identified. amongst species with validly published names, the closest species to the newly identified organisms were neisseria canis, n. dentiae, n. zoodegmatis, n. animaloris and n. weaveri. dna-dna hybridization studies demonstrated that the newly identified isolates represent species that are distinct from the ...201120173010
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