| unusual 22s-spirostane steroids from dracaena cambodiana. | from the methanol extract of dracaena cambodiana roots two unusual 22s-spirostane steroids (1beta,3beta,14alpha,20r,22s,25r)-spirost-5-ene-1,3,14-triol (1) and (lbeta,3beta,14alpha,15alpha,20r,22s,25r)-spirost-5-ene-tetrol (2) have been isolated, together with a known 22r-spirostane compound, namogenin b (3). their structures were elucidated by spectroscopic and spectrometric methods, including hrms and extensive 1d and 2d nmr spectroscopy. compound 1 showed significant antimicrobial activity ag ... | 2009 | 19831028 |
| cytotoxic and antibacterial flavonoids from dragon's blood of dracaena cambodiana. | chemical studies on the constituents from the dragon's blood of dracaena cambodiana led to the discovery of three new flavonoid derivatives ( 1- 3) and six known compounds ( 4- 9). the structures of the three new compounds were elucidated by nmr and ms spectroscopic analyses. all compounds were evaluated for their growth inhibitory activity against human cell lines k-562, smmc-7721, and sgc-7901, as well as antibacterial activities against staphylococcus aureus and methicillin-resistant staphylo ... | 2011 | 21800280 |
| cloning, bioinformatics and the enzyme activity analyses of a phenylalanine ammonia-lyase gene involved in dragon's blood biosynthesis in dracaena cambodiana. | phenylalanine ammonia-lyase (pal) is the key enzyme of the phenylpropanoid pathway, playing an important role in plant development and defence. we cloned a partial cdna of pal gene, dcpal1, from dracaena cambodiana seedlings using rt-pcr with degenerate primers that were designed based on a multiple sequence alignment of known pal genes from other plant species. dcpal1 shows highly homologous to other known pal genes registered in genbank, being closest to that of musa acuminata. dcpal1 has a re ... | 2013 | 23108992 |
| [antibacterial components from artificially induced dragon's blood of dracaena cambodiana]. | ten compounds were isolated from the artificially induced dragon's blood of dracaena cambodiana by various column chromatographies on silica and sephadex lh-20 gel. based on spectral analysis of nmr and ms, their structures were identified as 3, 4-dihydroxyallylbenzene (1), 3', 4', 5'-trimethoxycinnamylalcohol (2), pinoresinol (3), (2r)-7, 4'-dihydroxy-8-methylflavane (4), (2r)-7,4'-dihydroxy-5-methoxy-8-methylflavane(5),(2s)-7,3'-dihydroxy-4'-methoxy-8-methylflavane(6) ,(2s)-4',7-dihydroxy-6, 8 ... | 2015 | 27062817 |
| a new steroidal saponin from dragon's blood of dracaena cambodiana. | phytochemical study on dragon's blood of dracaena cambodiana led to a new steroidal saponin, cambodianoside g(1), and six known ones (2-7). the structure of the new compound was elucidated on the basis of detailed spectroscopic analysis. evaluation of antibacterial activities showed that compound 7 exhibited antibacterial activity against staphylococcus aureus. | 2015 | 25523446 |
| metabolites from endophytic fungus a12 of dracaena cambodiana. | a new drimane sesquiterpene, 1α,7α-dihydroxyconfertifolin (1), along with two known compounds 2 and 3, was isolated from endophytic fungus a12 of dracaena cambodiana. the new compound was elucidated by hr-esi-ms and spectroscopic techniques (ir, uv, 1d, and 2d nmr). compound 2 showed inhibitory bacterial activity against staphylococcus aureus with diameter of the inhibition zone of 13.5 mm. | 2012 | 22568775 |
| de novo transcriptome characterization of dracaena cambodiana and analysis of genes involved in flavonoid accumulation during formation of dragon's blood. | dragon's blood is a red resin mainly extracted from dracaena plants, and has been widely used as a traditional medicine in east and southeast asia. the major components of dragon's blood are flavonoids. owing to a lack of dracaena plants genomic information, the flavonoids biosynthesis and regulation in dracaena plants remain unknown. in this study, three cdna libraries were constructed from the stems of d. cambodiana after injecting the inducer. approximately 266.57 million raw sequencing reads ... | 2016 | 27922066 |
| transcriptome-wide identification and expression analysis of glutathione s-transferase genes involved in flavonoids accumulation in dracaena cambodiana. | dragon's blood is a traditional medicine widely used in the world, and the main components of which are flavonoids. however, little is known about its formation mechanism. previous studies indicate that plant glutathione s-transferase (gst) genes are involved in transportation of flavonoids from cytosolic synthesis to vacuolar accumulation. in this study, 20 dracaena cambodiana gst genes (dcgsts) were identified based on transcriptome database. phylogenetic analysis revealed that 20 dcgsts belon ... | 2016 | 27208821 |
| flavonoids produced by tissue culture of dracaena cambodiana. | dragon's blood is a traditional medicine used in many countries of many cultures because of its various therapeutic uses, and its main bioactive compounds are flavonoids, which mainly exhibit antitumor and antimicrobial activities. in the process of tissue culture of dracaena cambodiana, one of its resource plants, red secretion was discovered in the culture when 6-benzylaminopurine was added. analysis of its constituents by hplc in comparison with dragon's blood and the standards proved that 17 ... | 2014 | 24660458 |
| steroidal saponins from dragon's blood of dracaena cambodiana. | six new steroidal saponins, cambodianosides a-f (1-6), together with seven known ones, were isolated from the dragon's blood of dracaena cambodiana. the structures of 1-6 were elucidated on the basis of detailed spectroscopic analysis, including 1d and 2d nmr techniques and chemical methods. the cytotoxicities of all the isolated compounds were evaluated in vitro against three human cancer cell lines, and compounds 7, 8, and 11 showed significant inhibitory activities. | 2014 | 24480383 |
| tertiary origin and pleistocene diversification of dragon blood tree (dracaena cambodiana-asparagaceae) populations in the asian tropical forests. | the origin of extraordinarily rich biodiversity in tropical forests is often attributed to evolution under stable climatic conditions over a long period or to climatic fluctuations during the recent quaternary period. here, we test these two hypotheses using dracaena cambodiana, a plant species distributed in paleotropical forests. | 2013 | 23560070 |
| stimulation of dragon's blood accumulation in dracaena cambodiana via fungal inoculation. | dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. however, studies on enhancing the rapid accumulation of dragon's blood in dracaena cambodiana and determining its formation mechanism are unavailable. in this study, the activities of two fungi, namely, bjdc01 and bjdc05, and their effect on promoting the accumulation of five main compositions of dragon's blood in d. cambodiana were investigated for the first time. results of field tests co ... | 2013 | 23518260 |
| hplc analysis and cytotoxic activity of vernonia cinerea. | the extracts of five cambodian medicinal plants (aganosma marginata, dracaena cambodiana, harrisonia perforata, hymenodictyon excelsum and vernonia cinerea) were evaluated in vitro for their cytotoxic activity against ht29 colon adenocarcinoma cells and hepg2 hepatoma cells, using the mtt assay. among these five plants, vernonia cinerea displayed potent cytotoxicity. one main sesquiterpene lactone, 8alpha-tigloyloxy-hirsutinolide-13-o-acetate was isolated from the whole plant of v. cinerea. this ... | 2012 | 23156983 |
| two new antimicrobial flavanes from dragon's blood of dracaena cambodiana. | two new flavonoids, named cambodianins d (1) and e (2), together with two known flavanes (2s)-7,4'-dihydroxy-6,8-dimethylflavane (3) and (2s)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (4), were isolated from dragon's blood of dracaena cambodiana. the new compounds were determined by hr-esi-ms and spectroscopic techniques (uv, ir, 1d, and 2d nmr). compounds 1-3 exhibited antimicrobial activities. | 2012 | 22435715 |
| low genetic diversity and local adaptive divergence of dracaena cambodiana (liliaceae) populations associated with historical population bottlenecks and natural selection: an endangered long-lived tree endemic to hainan island, china. | historical population bottlenecks and natural selection have important effects on the current genetic diversity and structure of long-lived trees. dracaena cambodiana is an endangered, long-lived tree endemic to hainan island, china. our field investigations showed that only 10 populations remain on hainan island and that almost all have been seriously isolated and grow in distinct habitats. a considerable amount of genetic variation at the species level, but little variation at the population l ... | 2012 | 22404781 |
| isolation and characterization of microsatellite markers in an endangered species dracaena cambodiana (liliaceae). | • | 2010 | 21616789 |
| antioxidant phenolic compounds of dracaena cambodiana. | the antioxidant activities of the petroleum ether, ethyl acetate, n-buoh and water extract fractions from dracaena cambodiana pierre ex gagnep were evaluated in this study. the ethyl acetate fraction contained the highest amount of total phenolics and total flavonoids, and showed the greatest dpph˙, abts+ and superoxide anion radical-scavenging capacities. the dpph˙, abts+ and superoxide anion radical-scavenging capacities of nine compounds isolated from the ethyl acetate fraction were also eval ... | 2010 | 21135802 |
| a new cytotoxic homoisoflavonoid from dracaena cambodiana. | a new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2s)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (2) and (2r)-7,4'-dihydroxy-8-methylflavane (3), were isolated from the stems of dracaena cambodiana. their structures were determined based on hr-esi-ms and spectroscopic techniques (uv, ir, 1d-, and 2d-nmr). compound 1 exhibited significant cytotoxic activities against k562 and sgc-7901 with the ic(50) values of 1.4 and 2.9 microg/ml, respectively. | 2009 | 19219735 |
| [study on the new use of antitumor of dracaena cambodiana]. | to screen the antitumor extract from dracaena cambodiana pierre ex gagnep. | 2005 | 16479920 |