| discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. | recently, we reported the discovery of three novel coronaviruses, bulbul coronavirus hku11, thrush coronavirus hku12, and munia coronavirus hku13, which were identified as representatives of a novel genus, deltacoronavirus, in the subfamily coronavirinae. in this territory-wide molecular epidemiology study involving 3,137 mammals and 3,298 birds, we discovered seven additional novel deltacoronaviruses in pigs and birds, which we named porcine coronavirus hku15, white-eye coronavirus hku16, sparr ... | 2012 | 22278237 |
| coronavirus genomics and bioinformatics analysis. | the drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known rna viruses, with g + c contents varying from 32% to 43%. variable numbers of small orfs are present between the various conserved genes (orf1ab, spike, envelope, membrane and nucleocapsid) and downstrea ... | 2010 | 21994708 |
| coronavirus diversity, phylogeny and interspecies jumping. | the sars epidemic has boosted interest in research on coronavirus biodiversity and genomics. before 2003, there were only 10 coronaviruses with complete genomes available. after the sars epidemic, up to december 2008, there was an addition of 16 coronaviruses with complete genomes sequenced. these include two human coronaviruses (human coronavirus nl63 and human coronavirus hku1), 10 other mammalian coronaviruses [bat sars coronavirus, bat coronavirus (bat-cov) hku2, bat-cov hku4, bat-cov hku5, ... | 2009 | 19546349 |
| discovery and sequence analysis of four deltacoronaviruses from birds in the middle east reveal interspecies jumping with recombination as a potential mechanism for avian-to-avian and avian-to-mammalian transmission. | the emergence of middle east respiratory syndrome showed once again that coronaviruses (covs) in animals are potential source for epidemics in humans. to explore the diversity of deltacoronaviruses in animals in the middle east, we tested fecal samples from 1,356 mammals and birds in dubai, the united arab emirates. four novel deltacoronaviruses were detected from eight birds of four species by reverse transcription-pcr (rt-pcr): falcov uae-hku27 from a falcon, houcov uae-hku28 from a houbara bu ... | 2018 | 29769348 |