| [demodex folliculorum and demodex brevis (acarida) as the factors of chronic marginal blepharitis]. | group 568 patients with chronic marginal blepharitis was investigated for the presence of demodex folliculorum and d. brevis on palpebral margins. the parasites were found in 387 cases (68% examined population). d. folliculorum--258 (67%) and d. brevis--129 (33%). | 1991 | 1823473 |
| [quantitative study on infestation and distribution of human demodex on the face]. | we have tried to use 1.2 cm x 5 cm (6 cm2) adhesive cellophane tape technique for quantitative detection of demodex. 618 mites were detected on the 24 tapes applied on various parts of the face of a healthy individual. in an investigation of 8 person-times, the numbers of mites found on various parts of the face were in the following order: upper-cheek (233), mid-cheek (153), lower-cheek (114), chin (78), forehead (59.5), nose (55), infraorbital (54.5), paraoral (49.5), nasal groove (45), mites ... | 1990 | 2095998 |
| incidence of demodex folliculorum on skin of lids and nose. | the incidence of follicle mites (demodex) has been studied in 206 non-selected subjects by means of adhesive tape impressions on skin during daytime of nose and lids and moist storage of the tape. the incidence was seen to rise with increasing age: 4% in young subjects, 30% in the age group of 20 to 80, and 47% in older. the mite was more often present on the skin of the nose (17%) than on that of the upper lid (8%), while the incidence on the lower lid was between these 2 extremes (13%). a tota ... | 1982 | 6760659 |
| immune response in demodicosis. | demodex folliculorum and demodex brevis are obligatory parasites in the hair follicles and in the pilosebaceous glands. although most people are infested with these mites, only a small number develop the clinical symptoms of demodicosis. the objective of this study was to determine the distinguishing features of the immune response to the infestation of the skin by demodex mites. | 2004 | 15196158 |
| a clinico-pathological approach to the classification of human demodicosis. | demodicosis is a parasitic skin disease caused by the follicle mites demodex folliculorum and demodex brevis. although there are several clinical variants of this disease, a clear classification is missing. | 2005 | 16033479 |
| [investigations on the occurrence as well as the role of demodex follicuforum and demodex brevis in the pathogensis of blepharitis]. | the aim of the paper was to describe the prevalence and the role of demodex folliculorum and demodex brevis in the pathogenesis of chronic blepharitis. | 2005 | 16052809 |
| [distribution and control of acari as vectors of human disease in urban population of moscow]. | human ectoparasites, such as itch mites and the follicular mites demodex brevis and d. folliculorum are notified on the territory of moscow. the bird and rodent mites ornythonyssus bacoti and the larvae of harvest mites may attack human beings indoors. the ticks ixodes ricinus and i. persulcatus begin to inhabit the tree belts and environs of moscow and other cities and towns. in the cities and towns of more southern regions of the russian federation, the red hen-mites dermanyssus gallinae are a ... | 2005 | 16212087 |
| [experimental and clinical studies on the effect of sodium dodecylbenzene sulfonate in in vitro killing demodex and in treating demodicidosis]. | to observe the effect of sodium dodecylbenzene sulfonate (sdbs) in killing demodex in vitro and in the treatment of demodicidosis. | 2005 | 16296612 |
| [frequency of the appearance of demodex sp. in various patient and age groups]. | demodex folliculorum and demodex brevis are acari that can be found in hair follicles and sebaceous glands of the skin, especially on face of humans. in this study, demodex sp was investigated in regard to allergic diseases, age and gender. a total of 197 patients (117 with rosacea, 29 with akne vulgaris, and 51 with allergic diseases) were examined using the standardized skin surface biopsy (sssb) and 97 out of 197 (49.23%) cases were found to be positive by the inonu university medical faculty ... | 2007 | 17594651 |
| under the lash: demodex mites in human diseases. | demodex mites, class arachnida and subclass acarina, are elongated mites with clear cephalothorax and abdomens, the former with four pairs of legs. there are more than 100 species of demodex mite, many of which are obligatory commensals of the pilosebaceous unit of mammals including cats, dogs, sheep, cattle, pigs, goats, deer, bats, hamsters, rats and mice. among them, demodex canis, which is found ubiquitously in dogs, is the most documented and investigated. in excessive numbers d. canis caus ... | 2009 | 20664811 |
| influence of temperature and medium on viability of demodex folliculorum and demodex brevis (acari: demodicidae). | demodex folliculorum and d. brevis are cosmopolitan, obligatory parasites. epidemiological studies have established a clear association between these species and various facial diseases in humans. however, not much is known of the ecology of these mites, also because it has proven difficult to culture them. here we report a laboratory study on the (combined) effects of temperature and culture medium on the viability of both species. results showed significant differences in the survival time of ... | 2011 | 21479960 |
| demodex folliculorum and demodex brevis as a cause of chronic marginal blepharitis. | intensive long-term studies of demodex spp. (d.) and its role in chronic blepharits have been carried out in recent years by scientists from the pomeranian medical university in szczecin. it has resulted in numerous publications, spurring a lot of interest worldwide. a few of the papers have been cited in leading american medical journals. in recent years many papers dealing with demodicosis of the eyelids have been published worldwide. based on the growing interest in the role of demodex spp. i ... | 2007 | 18561612 |
| cloning and sequence analysis of chitin synthase gene fragments of demodex mites. | to our knowledge, few reports on demodex studied at the molecular level are available at present. in this study our group, for the first time, cloned, sequenced and analyzed the chitin synthase (chs) gene fragments of demodex folliculorum, demodex brevis, and demodex canis (three isolates from each species) from xi'an china, by designing specific primers based on the only partial sequence of the chs gene of d. canis from japan, retrieved from genbank. results show that amplification was successf ... | 0 | 23024043 |
| scalp demodicidosis mimicking favus in a 6-year-old boy. | demodex folliculorum and demodex brevis are obligatory ectoparasites of the pilosebaceous unit in humans. although most people are infested with these mites, only a small number develop clinical symptoms of demodicidosis. we report a case of demodicidosis in a 6-year-old boy who had lesions on the scalp, forehead, neck, and anterior chest for 18 months. our clinical diagnosis at the time was favus. the microscopic examination of the hair in a 10% potassium hydroxide preparation showed no fungal ... | 2007 | 17637363 |
| corneal manifestations of ocular demodex infestation. | to report the corneal manifestations in eyes with demodex infestation of the eyelids. | 2007 | 17376393 |
| [symptomatic and asymptomatic infections of demodex spp. in eye lashes of patients of different age groups]. | demodex folliculorum and demodex brevis were looked for on eyelashes sampled from 481 people, aged 3 through 96. the persons studied were divided into 9 age groups. magnitude of the infection symptoms was assessed based on macroscopic changes of eye-lid edges and on interviews with patients. an increase of the prevalence of infection and intensification of the symptoms were observed to coincide with the age increase of the persons studied. no significant differences were demonstrated between the ... | 2004 | 16892605 |
| [demodex as an etiological factor in chronic blepharitis]. | to present and account the results of newest experimental and clinical investigations on the role of demodex folliculorum and demodex brevis in the etiology of chronic blepharitis. | 2005 | 16619830 |
| [chronic blepharitis and demodex]. | demodex is a mite commonly found in eyelash hair follicles and sebaceous glands of healthy people. due to the fact this mite has also been reported in many chronic cases of blepharitis, we aimed to investigate the incidence of infestation with this mite in healthy people and in patients with chronic blepharitis, in addition to evaluating the response to the different treatments used for blepharitis. | 2005 | 16311952 |
| high prevalence of demodex in eyelashes with cylindrical dandruff. | to determine the prevalence of demodex in eyelashes with cylindrical dandruff (cd). | 2005 | 16123406 |
| high prevalence of demodex spp. infestation among patients with posterior blepharitis: correlation with age and cylindrical dandruff. | to determine prevalence of demodex spp. and infestation index (ii) by the parasite among patients of different ages with blepharitis and to assess association with occurrence of cylindrical dandruff (cc). | 2017 | 28552438 |
| the effect of skin moisture, ph, and temperature on the density of demodex folliculorum and demodex brevis (acari: demodicidae) in students and staff of the erzincan university, turkey. | the aim of this study was to determine the prevalence and density of demodex folliculorum and demodex brevis in students and staff of the erzincan university, turkey, and to define the influence of age, gender, educational level, and hygiene as well as skin moisture, ph, and temperature on the presence of demodex mites. | 2017 | 28369843 |
| prevalence of ocular demodicosis among patients at tertiary care center, bangkok, thailand. | to determine the prevalence of ocular demodicosis by both microscopic examination and molecular detection among patients at king chulalongkorn memorial hospital, thai red cross society, bangkok. | 2017 | 28149788 |
| demodicidosis in a child with xantholeukaemia associated with type 1 neurofibromatosis. | although demodex follicularum and demodex brevis are common permanent ectoparasites of human pilosebaceous units, their incidence on children's skin is rare. we report a new case of demodicidosis in a 22-month-old girl undergoing chemotherapy for chronic myelomonocytic leukaemia associated with xanthoma and type 1 neurofibromatosis. the eruption cleared after oral and topical metronidazole therapy. demodicidosis should be included in the differential diagnosis of facial eruption in immunosuppres ... | 2003 | 12804999 |
| particular features of immune response after invasion of different species of human demodex mites. | the purpose of the present study was to find peculiarities of the immune response to the invasion of demodex folliculorum and demodex brevis mites. sixty-six patients with human demodicosis were included in this study. the demodex mites' density was more than 5 per 1 cm(2). the immune response was evaluated by the identification of membrane markers of the different immune cells by monoclonal antibodies. a significant decrease of the percentage of various parameters was found: the decrease for cd ... | 2001 | 12687239 |
| [investigation on the prevalence of human demodex among 2,248 medical students in inner mongolia]. | to understand the difference of demodex prevalence among medical students living and studying together with different classes, sexes and nationalities. | 2001 | 12571975 |
| demodex mites in acne rosacea. | the hair follicle mites demodex folliculorum and demodex brevis and their role in the pathogenesis of rosacea have been the subject of much debate in the past. we studied the prevalence of demodex mites in facial skin biopsies obtained from 80 patients with rosacea, 40 with facial eczematous eruption and 40 with lupus erythematosus discoides. the mite prevalence in the rosacea group (51%) was significantly higher than in the rest of the study population (eczema 28% and lupus discoides 31%). demo ... | 1998 | 9870674 |
| demodicidosis in immunocompetent young children: report of eight cases. | demodex folliculorum and demodex brevis are obligate parasites of the human pilosebaceous unit. they are the most common permanent ectoparasites in adults, but their incidence on children's skin is rare. only few cases of demodicidosis have been reported in children aged below 5 years and most of them were suffering from leukemia or hiv infection. the aim of this study is to describe demodicidosis in young immunocompetent children. the clinical details of 8 healthy children are given. there were ... | 1997 | 9407170 |
| identification of a third feline demodex species through partial sequencing of the 16s rdna and frequency of demodex species in 74 cats using a pcr assay. | demodex cati and demodex gatoi are considered the two demodex species of cats. however, several reports have identified demodex mites morphologically different from these two species. the differentiation of demodex mites is usually based on morphology, but within the same species different morphologies can occur. dna amplification/sequencing has been used effectively to identify and differentiate demodex mites in humans, dogs and cats. | 2015 | 26178604 |
| the association of demodex with chalazia: a histopathologic study of the eyelid. | to investigate the association of demodex with chalazia and to describe the associated histopathologic changes in the eyelid tissue. | 2017 | 26108058 |
| recent advances on ocular demodex infestation. | to summarize recent advances on ocular demodex infestation. | 2015 | 26058028 |
| the demodex mite population in rosacea. | the cause of rosacea is unknown; among other factors a causative role has been postulated for the hair follicle mites demodex folliculorum and demodex brevis. | 1993 | 8445060 |
| [the prevalence of demodex folliculorum and demodex brevis in a population sample from botucatu, são paulo, brazil]. | a survey was conducted to determine the prevalence of d. folliculorum and d. brevis for the first time in brazil. in this study, association between the presence of mites and host factors (age, sex and race) were analysed. samples were obtained from 100 individuals submitted to a facial cleaning in an aesthetic clinic in botucatu city. all the samples were mounted in berlese's medium and examined by dark-field phase microscopy. from 100 studied individuals, 72 were positive, among the positive c ... | 1993 | 8159822 |
| demodicosis of ophthalmic concern. | hair-follicle mites are the only metazoan organism commonly found in the pilosebaceous components of the eyelid of man. our study showed that demodex folliculorum in all stages is found in the small hair follicles and the eyelash hair follicles. this species, in adult and immature forms, consumes epithelial cells, produces follicular distension and hyperplasia, and increases keratinization leading, in eyelashes, to cuffing consisting of keratin and lipid moieties. demodex brevis (in all stages) ... | 1981 | 7211994 |
| demodex folliculorum and demodex brevis in cutaneous biopsies. | the hair follicle mites demodex folliculorum and demodex brevis are ubiquitous obligatory ectoparasites of man. we studied these mites in a consecutive series of skin biopsies submitted to a dermatopathology laboratory; 10% of all biopsies and 12% of all follicles contained demodectic mites. the prevalence of both species increased with age, but d. brevis had a lower prevalence. the face was most heavily infested by both species, but d. brevis had a wider distribution on the body. males were mor ... | 1982 | 7142466 |
| the hair follicle mites demodex folliculorum and demodex brevis: biology and medical importance. a review. | | 1981 | 6453029 |
| [the epidemiology of demodex mites at the college students living in dormitories in the city of ordu]. | demodex folliculorum and demodex brevis can cause different skin and eye symptoms. there are indications showing that the prevalence of these parasites is higher in public places. in this direction, the study was aimed to determine the prevalence of demodex in university students, inhabiting in dormitories. | 2014 | 25308453 |
| clinical manifestations of demodicosis. | this article reacquaints the practitioner with the existence of two common ectoparasites of the ocular adnexa, demodex folliculorum and demodex brevis. their history, habitat, life stages, prevalence, pathogenicity as well as diagnosis, treatment and prognosis are reviewed. the mild controversy of whether these organisms are true pathogens is discussed. | 1986 | 3794168 |
| [scanning electron microscopic observation on demodex brevis]. | this paper presents the first description of the morphology of demodex brevis examined by scanning electron microscopy. the authors found that d. brevis can be distinguished from d. folliculorum by the characteristic features of the following structures: the flat gnathosoma, the humplike podosoma and the absence of transverse striation on its anterior dorsal surface, the supracoxal spines, the hypostome, the oral opening, the pedipalpal claws and the claws on legs, and the annuli of the terminal ... | 1992 | 1307282 |
| scanning electron microscopy of demodex brevis (folliculorum). | | 1977 | 73329 |
| [acaricidal activities of the water extract of xiushan sea mud against human demodex mites]. | to observe the acaricidal effect of the water extract of xiushan sea mud on demodex brevis and d. folliculorum. | 2011 | 21972598 |
| rapd-scar marker and genetic relationship analysis of three demodex species (acari: demodicidae). | for a long time, classification of demodex mites has been mainly based on their hosts and phenotype characteristics. the study was the first to conduct molecular identification and genetic relationship analysis for six isolates of three demodex species by random amplified polymorphic dna (rapd) and sequence-characterized amplified region (scar) marker. totally, 239 dna fragments were amplified from six demodex isolates with 10 random primers in rapd, of which 165 were polymorphic. using a single ... | 2011 | 22205351 |
| risk factors and prevalence of demodex mites in young adults. | demodex mites are ectoparasites often found in follicles of facial skin. their role in human diseases is under investigation, and a growing number of studies indicated that they contribute to chronic inflammatory conditions of the skin, such as rosacea, blepharitis, otitis externa, alopecia and folliculitis. in our study we tested 96 healthy adults for the presence of demodex mites. risk factors influencing presence of mites and skin types of the tested individuals were evaluated. we found demod ... | 2011 | 21715284 |
| the effect of temperature on the viability of demodex folliculorum and demodex brevis. | demodex folliculorum and demodex brevis are obligatory parasites of the pilosebaceous unit in humans and are cosmopolitan in terms of their distribution. this study was conducted to explore the effect of temperature on the viability of d. folliculorum and d. brevis. both types of parasites were collected with the cellophane tape method, then randomly grouped and placed into separate moist cabinets. they were divided into 15 groups and exposed to experimental temperatures ranging from -15 degrees ... | 2009 | 19774398 |
| [ectoparasites. part 2: bed bugs, demodex, sand fleas and cutaneous larva migrans]. | ectoparasites or epidermal parasites include a very heterogenous group of infections of the outer layers of the skin. worldwide the most common are scabies, lice, tungiasis, and hookworm-induced cutaneous larva migrans. in recent years, bed bug infestations in hotels or vacation homes seem to have become more frequent. demodex folliculorum and demodex brevis are found in the facial and scalp hair follicles in 95% of individuals. classic demodex folliculitis is often overlooked in differential di ... | 2009 | 19701614 |
| phylogenetic analysis of demodex caprae based on mitochondrial 16s rdna sequence. | demodex caprae infests the hair follicles and sebaceous glands of goats worldwide, which not only seriously impairs goat farming, but also causes a big economic loss. however, there are few reports on the dna level of d. caprae. to reveal the taxonomic position of d. caprae within the genus demodex, the present study conducted phylogenetic analysis of d. caprae based on mt16s rdna sequence data. d. caprae adults and eggs were obtained from a skin nodule of the goat suffering demodicidosis. the m ... | 2013 | 23996126 |
| molecular study on three morphotypes of demodex mites (acarina: demodicidae) from dogs. | canine demodicosis is a severe and highly prevalent dermatologic disease in dogs. pet dogs can be affected by three recognized demodex species that can produce clinical effects. in this paper, three morphological types of demodex mites have been isolated from spanish dogs. a complete morphobiometrical study of each one has been carried out. morphological and biometrical studies revealed three closely related populations with some distinctive characteristics and could be identified as demodex can ... | 2012 | 22895570 |
| significant correlation between meibomian gland dysfunction and keratitis in young patients with demodex brevis infestation. | to report the clinical characteristics and correlation between meibomian gland dysfunction (mgd) and keratitis in young patients with ocular demodicosis. | 2017 | 29055903 |
| ocular demodicosis as a potential cause of ocular surface inflammation. | among different species of mites, demodex folliculorum and demodex brevis are the only 2 that affect the human eye. because demodicosis is highly age-dependent and can be found in asymptomatic adults, the pathogenicity of these mites has long been debated. in this study, we summarize our research experience including our most recent study regarding demodex infestation as a potential cause of ocular inflammatory diseases. specifically, we describe the pathogenesis of demodicosis and then discuss ... | 2017 | 28902017 |
| demodex folliculorum and demodex brevis in healthy and immunocompromised patients. | to examine the proportion of demodex folliculorum and d. brevis in the eyelashes of healthy and immunocompromised patients. | 2013 | 23713917 |
| prevalence of demodex folliculorum and demodex brevis in childhood malnutrition and malignancy. | hair follicle mites, demodex folliculorum and demodex brevis, are known to accompany immune-deficiency states, however no study so far has investigated their presence in malnutrition. in this study we aimed to determine the prevalence of those mites in childhood malnutrition, malignancy and risk factors. | 2013 | 23039878 |
| human permanent ectoparasites; recent advances on biology and clinical significance of demodex mites: narrative review article. | demodex is a genus of mites living predominantly in mammalian pilosebaceous units. they are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. causation between demodex mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. clinical observations indicate a primary form of human demodex infection. the aim of this review was to highlight the biological aspects of demodex inf ... | 2017 | 28747952 |
| prevalence and density of demodex folliculorum and demodex brevis (acari: demodicidae) in erzincan province. | this study aimed to determine the prevalence and density of demodex folliculorum and d. brevis in erzincan province and the association between demodex spp. and skin moisture, ph, and temperature. | 2017 | 28695830 |
| association study of demodex bacteria and facial dermatoses based on dgge technique. | the role of bacteria is unclear in the facial skin lesions caused by demodex. to shed some light on this issue, we conducted a case-control study comparing cases with facial dermatoses with controls with healthy skin using denaturing gradient gel electrophoresis (dgge) technique. the bacterial diversity, composition, and principal component were analyzed for demodex bacteria and the matched facial skin bacteria. the result of mite examination showed that all 33 cases were infected with demodex f ... | 2017 | 28063008 |
| prevalence of demodex ectoparasites among humans in ordu province in turkey. | demodex folliculorum and demodex brevis are common ectoparasites in humans. demodex parasite infestations have not been determined in the province of ordu. we determined the prevalence of demodex species among humans in ordu provience, turkey. seven hundred ninety-nine subjects (438 males and 361 females) aged ≥ 18 years living in the central districts of ordu province, turkey, were selected using the world health organization cluster sampling method. a superficial skin biopsy of the face was ob ... | 2016 | 27244957 |
| demodex species in human ocular disease: new clinicopathological aspects. | demodex brevis and demodex folliculorum are likely ubiquitous organisms associated with human eyelashes. however, they have also been implicated in the pathogenesis of external ocular diseases. this article reviews the current literature in regards to life cycle, morphology, pathogenesis and treatment of underlying demodex spp. infestation and outlines the previously undescribed in vivo behaviour of the mites. images were obtained from the epilation of lashes from 404 patients seen in clinical p ... | 2017 | 27160273 |
| a rare clinical manifestation of spinulate demodicosis. | demodicosis is a chronic skin disease caused by demodex mites such as demodex folliculorum and demodex brevis. demodex mites live in pilosebaceous units and they are regarded as a part of the normal skin flora. nevertheless, it has been suggested that the presence of five or more mites per cm² by the standardized skin surface biopsy technique could be considered as pathogenic. | 2016 | 28329574 |
| unilateral demodicidosis of face mimicking hansens disease. | demodicosis is a common parasitic infection of the hair follicles and the pilosebaceous unit by the demodex mites viz. demodex folliculorum and demodex brevis. infection by this parasite is common among immunocompromised and elderly. we report a case of facial demodicosis which presented like atypical rosacea with a gradually progressing swelling and redness on right side of face which was initially diagnosed as a case of hansen's disease. skin biopsy revealed follicular dilatation with presence ... | 2016 | 28326184 |
| volatile oils of chinese crude medicines exhibit antiparasitic activity against human demodex with no adverse effects in vivo. | demodex is a type of permanent obligatory parasite, which can be found on the human body surface. currently, drugs targeting demodex usually result in adverse effects and have a poor therapeutic effect. thus, the aim of the present study was to investigate the use of chinese crude medicine volatile oils for targeting and inhibiting demodex in vitro. the volatile oils of six chinese crude medicines were investigated, including clove, orange fruit, manchurian wildginger, cinnamon bark, rhizome alp ... | 2015 | 25780426 |
| [primary human demodicosis. a disease sui generis]. | human demodex mites (demodex folliculorum and demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. the mode of symbiosis between humans and human demodex mites is unclear, while the pathogenicity of human demodex mites in many inflammatory skin diseases is now better understood. primary human demodicosis is a skin disease sui generis not associated with local or syst ... | 2015 | 25744530 |
| [demodex folliculorum and demodex brevis]. | demodex are cosmopolitan mites occurring in many species of mammals. two morphologically distinct demodex species parasitize on humans: demodexfolliculorum (simon, 1842) and demodex brevis (akbulatova, 1963). until recently, these species have been regarded as commensals; now they are considered as parasitic organisms. in people, demodex spp. can be found mainly in the sebaceous glands of the skin (mainly in the area of the forehead, cheeks, nose, behind ears and neck), in hearing aids, and on t ... | 2015 | 27116866 |
| complete mitochondrial genomes of the human follicle mites demodex brevis and d. folliculorum: novel gene arrangement, truncated trna genes, and ancient divergence between species. | follicle mites of the genus demodex are found on a wide diversity of mammals, including humans; surprisingly little is known, however, about the evolution of this association. additional sequence information promises to facilitate studies of demodex variation within and between host species. here we report the complete mitochondrial genome sequences of two species of demodex known to live on humans--demodex brevis and d. folliculorum--which are the first such genomes available for any member of ... | 2014 | 25515815 |
| phylogenetic relationships and new genetic tools for the detection and discrimination of the three feline demodex mites. | two feline demodex mite species have been described as causative agents of feline demodicosis, until recently a third species was detected. we provide an updated analysis on the phylogenetic relationship of demodex mites. in addition, we present the first qpcr assay for the detection and differentiation of all three feline mite species in a single reaction. specimen of demodex cati, demodex gatoi, and the recently discovered third species were collected from skin scrapings and fecal flotation fo ... | 2015 | 25468382 |
| molecular identification of four phenotypes of human demodex in china. | traditional classification of demodex mites by hosts and phenotypic characteristics is defective because of environmental influences. in this study, we proposed molecular identification of four phenotypes of two human demodex species based on mitochondrial cox1 fragments for the first time. mites collected from sufferers' facial skin were classified into four phenotypes: phenotype a-c with finger-like terminus, and phenotype d with cone-like terminus. the results of molecular data showed that co ... | 2014 | 24726960 |
| human demodicosis: revisit and a proposed classification. | human demodex mites (demodex folliculorum and demodex brevis) hold a high rank in the evolutionary and phylogenetic hierarchy of the skin microbiome, although in most people their presence is of no consequence. while human demodicosis is a skin disease sui generis, it can mimic many other inflammatory dermatoses, such as folliculitis, rosacea and perioral dermatitis, leading to unspecific and confusing descriptions in the literature. here, we propose to classify human demodicosis into a primary ... | 2014 | 24471456 |
| human demodex mite: the versatile mite of dermatological importance. | demodex mite is an obligate human ecto-parasite found in or near the pilo-sebaceous units. demodex folliculorum and demodex brevis are two species typically found on humans. demodex infestation usually remains asymptomatic and may have a pathogenic role only when present in high densities and also because of immune imbalance. all cutaneous diseases caused by demodex mites are clubbed under the term demodicosis or demodicidosis, which can be an etiological factor of or resemble a variety of derma ... | 2014 | 24470662 |
| demodex spp. infestation in a breast-cancer patient: a case report. | demodex folliculorum and demodex brevis are obligatory parasites that live in sebaceous glands and follicles. when immune system becomes suppressed by any reason, patients become vulnerable to obligatory parasites like d. folliculorum and d. brevis. immune system becomes suppressed in cancer patients who undergo chemotherapy, and as a result these patients become vulnerable to infestations. in our case, a 45 year-old female has been admitted to oncology clinic for a medical treatment of breast c ... | 2013 | 24403716 |
| high prevalence of demodex brevis infestation in chalazia. | to investigate the correlation between demodicosis and chalazia in patients with the latter. | 2014 | 24332377 |
| [investigation of the prevalance of demodex folliculorum and demodex brevis in rosacea patients]. | demodex spp. is an acari that resides in the hair follicles and sebaceous glands of the skin unit. it is known that demodex spp. may play a role in the pathogenesis of rosacea and acne. common sites of demodex infestation are the facial skin , forehead, cheeks, chin and nasolabial fold. this study was performed between january 2010 and december 2011. it was carried out in order to investigate the frequency of demodex folliculorum and demodex brevis among rosacea patients who presented to the fır ... | 2013 | 24192622 |
| molecular identification of four phenotypes of human demodex mites (acari: demodicidae) based on mitochondrial 16s rdna. | classification of demodex mites has long depended on hosts and morphological characteristics. however, the fact that two species coexist in the same host and phenotype is easily influenced by environment causes difficulty and indeterminacy in traditional classification. genotype, which directly reflects the molecular structure characteristics, is relatively stable. in this study, species identification of four phenotypes of human demodex mites was conducted. mites were morphologically classified ... | 2013 | 23949243 |
| demodex. | demodex folliculorum and demodex brevis are ectoparasites with an astounding prevalence of 100% in patients aged 70 years and older. every person in this age group is estimated to carry a colony of 1000 to 2000 mites. with such a high prevalence, little attention has been paid to the mite among eye care practitioners. we demonstrate a clinical sequence in a set of case reports to identify the mite. the clinical sequence includes a clinical history of blepharitis, dry eyes, and/or ocular allergy; ... | 2013 | 23748846 |
| sequencing for complete rdna sequences (18s, its1, 5.8s, its2, and 28s rdna) of demodex and phylogenetic analysis of acari based on 18s and 28s rdna. | due to the difficulty of dna extraction for demodex, few studies dealt with the identification and the phyletic evolution of demodex at molecular level. in this study, we amplified, sequenced, and analyzed a complete (demodex folliculorum) and an almost complete (d12 missing) (demodex brevis) ribosomal dna (rdna) sequence and also analyzed the primary sequences of divergent domains in small-subunit ribosomal rna (rrna) of 51 species and in large-subunit rrna of 43 species from four superfamilies ... | 2012 | 22903416 |
| prevalence of demodex mites in eyelashes among people of oaxaca, mexico. | this study was carried out to determine the prevalence of demodex mites in eyelashes of people from different places from oaxaca. one thousand and ten patients underwent epilation of eight eyelashes from each eye and they were processed to search demodex which was found in 208 (20%) of the patients and among them male was more affected than female, 119 (57%) and 89 (43%), respectively. there was not found a relationship between clinical manifestations among these patients since 101 (49%) and 107 ... | 2012 | 22750785 |
| phylogenetic relationships in demodex mites (acari: demodicidae) based on mitochondrial 16s rdna partial sequences. | to confirm phylogenetic relationships in demodex mites based on mitochondrial 16s rdna partial sequences, mtdna 16s partial sequences of ten isolates of three demodex species from china were amplified, recombined, and sequenced and then analyzed with two demodex folliculorum isolates from spain. lastly, genetic distance was computed, and phylogenetic tree was reconstructed. mega 4.0 analysis showed high sequence identity among 16s rdna partial sequences of three demodex species, which were 95.85 ... | 2012 | 22581346 |
| complete sequence analysis of 18s rdna based on genomic dna extraction from individual demodex mites (acari: demodicidae). | the study for the first time attempted to accomplish 18s ribosomal dna (rdna) complete sequence amplification and analysis for three demodex species (demodex folliculorum, demodex brevis and demodex canis) based on gdna extraction from individual mites. the mites were treated by dna release additive and hot start ii dna polymerase so as to promote mite disruption and increase pcr specificity. determination of d. folliculorum gdna showed that the gdna yield reached the highest at 1 mite, tending ... | 2012 | 22414329 |
| in vivo confocal microscopy as a novel and reliable tool for the diagnosis of demodex eyelid infestation. | demodex mites are implicated in several ocular surface diseases such as blepharitis, ocular rosacea and dry eye syndrome. demodex eyelid infestation is classically diagnosed by analysing depilated eyelashes under the light microscope. the use of in vivo confocal microscopy (ivcm) could be an easy way to improve its diagnosis. the ability of ivcm to identify demodex was evaluated and compared with the classic depilation method. | 2015 | 25253768 |
| neutrophilic sebaceous adenitis with intralobular demodex mites: a case report and review of the literature. | a 61-year-old white man presented with a 1-week history of an asymptomatic erythematous, annular plaque with minimal scale limited to the nasal bridge. histological examination showed a mixed infiltrate of lymphocytes and neutrophils within sebaceous glands. the clinical and histopathological presentation was consistent with a diagnosis of neutrophilic sebaceous adenitis. several demodex brevis mites were present deep within the affected sebaceous lobules. demodex brevis mites are uncommon inhab ... | 2015 | 25229566 |
| molecular identification and phylogenetic study of demodex caprae. | the dna barcode has been widely used in species identification and phylogenetic analysis since 2003, but there have been no reports in demodex. in this study, to obtain an appropriate dna barcode for demodex, molecular identification of demodex caprae based on mitochondrial cox1 was conducted. firstly, individual adults and eggs of d. caprae were obtained for genomic dna (gdna) extraction; secondly, mitochondrial cox1 fragment was amplified, cloned, and sequenced; thirdly, cox1 fragments of d. c ... | 2014 | 25132566 |
| prevalence of demodex spp. in eyelash follicles in different populations. | the pathologic relevance of demodex infestation in blepharitis is still controversial. the aim of the study was to determine the prevalence of demodex spp. in eyelash follicles and its relationship to eye symptoms. | 2014 | 24904668 |