| host switch during evolution of a genetically distinct hantavirus in the american shrew mole (neurotrichus gibbsii). | a genetically distinct hantavirus, designated oxbow virus (oxbv), was detected in tissues of an american shrew mole (neurotrichus gibbsii), captured in gresham, oregon, in september 2003. pairwise analysis of full-length s- and m- and partial l-segment nucleotide and amino acid sequences of oxbv indicated low sequence similarity with rodent-borne hantaviruses. phylogenetic analyses using maximum-likelihood and bayesian methods, and host-parasite evolutionary comparisons, showed that oxbv and asa ... | 2009 | 19394994 |
| novel serological tools for detection of thottapalayam virus, a soricomorpha-borne hantavirus. | we developed serological tools for the detection of hantavirus-specific antibodies and hantavirus antigens in shrews. the work was focussed to generate thottapalayam virus (tpmv)-specific monoclonal antibodies (mabs) and anti-shrew immunoglobulin g (igg) antibodies. the mabs against tpmv nucleocapsid (n) protein were produced after immunization of balb/c mice with recombinant tpmv n proteins expressed in escherichia coli, baculovirus and saccharomyces cerevisiae-mediated expression systems. in t ... | 2012 | 22828778 |
| molecular phylogeny of a newfound hantavirus in the japanese shrew mole (urotrichus talpoides). | recent molecular evidence of genetically distinct hantaviruses in shrews, captured in widely separated geographical regions, corroborates decades-old reports of hantavirus antigens in shrew tissues. apart from challenging the conventional view that rodents are the principal reservoir hosts, the recently identified soricid-borne hantaviruses raise the possibility that other soricomorphs, notably talpids, similarly harbor hantaviruses. in analyzing rna extracts from lung tissues of the japanese sh ... | 2008 | 18854415 |