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[concerning findings of scopulariopsis brevicaulis (sacc.) bainier, 1907, in pathologically changed nails and skin (author's transl)]. 1977139197
[scopulariopsis brevicaulis as an agent of onychomycosis]. 1976151493
[randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)].trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ...1975239503
growth of fungi in broiler houses.the growth of fungi in broiler houses with and without histories of problems of unknown etiology or of mycotoxicoses was studied. fungal growth data were obtained by the strip bait method and results expressed as frequency and relative density. the frequency and relative density of fungal growth of several species were higher in problem houses than in those without problems. in problem houses many known toxic fungi and several fungi of unknown toxicity were found growing, increasing in density a ...1977605041
[mycotic panophthalmitis caused by scopulariopsis brevicaulis]. 19761035497
sensitivity of scopulariopsis brevicaulis to some antimicrobial agents.sensitivity tests were done against two isolates of scopulariopsis brevicaulis, using amphotericin b in combination with chloramphenicol, chloramphenicol alone, amphotericin b in combination with 5-fluorocytosine, and 5-fluorocytosine, myxin and clotrimazole alone. results indicated that the effectiveness of amphotericin b was improved in the presence of chlormaphenicol or 5-fluorocytosine. growth inhibitory values recorded for chloramphenicol alone and combined with amphotericin b did not show ...19751240599
sudden infant death syndrome (sids) and the toxic gas hypothesis: microbiological studies of cot mattresses.1. fifty infants' mattresses were studied to investigate the occurrence of viable fungal and bacterial propagules, with particular reference to scopulariopsis brevicaulis which had been suggested to be implicated in sids cases. a total of 19 sids cases mattresses, 1 non-sids death, 20 used controls, and 10 new unused controls were examined. 2. differences were found between sids and used controls in the variety of fungal species isolated and the numbers isolated from fillings; bacterial numbers ...19921358149
effect of keratin on the lipid composition of scopulariopsis brevicaulis (bainier).lipid content and composition of scopulariopsis brevicaulis cultured with or without its natural substrate keratin was investigated. lipid content was found to be lower in the presence of keratin (maximum 12% against 19% in the absence of keratin), with differences in levels of linoleic acid (c18 = 2), palmitic (c16:0) and to a lesser extent palmitoleic (c16 = 1) and alpha-linolenic (c18 = 3) acids. the degree of unsaturation was correspondingly lower in the organisms cultured with keratin as su ...19921383824
in vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity.1-[(2-fluorophenyl)(4-fluorophenyl)phenylmethyl]-1h-imidazole (flutrimazole, ur-4056, cas 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (mic = 0.025-5.0 micrograms/ml). in most of these studies the activity of flutrimazole was comparable to that of clotrimazole and markedly higher than that of bifonazole (mic differences of greate ...19921418042
purification and partial characterization of two extracellular keratinases of scopulariopsis brevicaulis.two extracellular keratinases of scopulariopsis brevicaulis were purified and partially characterized. the enzymes were isolated by the techniques of gel filtration chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page). these keratinases (k i & k ii) were purified approximately 33 and 29 fold, respectively. sds-page of the products of gel filtration chromatography (k i & ii) produced only one band each, suggesting homogeneity. the optimum ph for both keratinases ...19921435957
keratinophilic fungi and other moulds associated with air-dust particles from egypt.one-hundred and eleven species and three species varieties belonging to 39 genera were collected from 50 dust samples on the five media used at 28 degrees c. using the hair-baiting technique with horse hair, 10 species of chrysosporium were isolated: c. asperatum, c. state of arthroderma tuberculatum, c. indicum, c. inops, c. keratinophilum, c. merdarium, c. pannorum, c. queenslandicum, c. tropicum and c. xerophilum. true dermatophytes were isolated: trichophyton verrucosum and trichophyton sp. ...19901702081
prevalence of superficial mycoses in the aosta valley region of italy from 1984 to 1989.this report represents the results of the culture tests for fungi carried out in the aosta valley region of italy from 1984 to 1989. the pathological material consisted of cutaneous scales, hair and nails. it was possible to identify 91.8% of the isolates: out of these, 36.1% were dermatophytes, 21% were aspergillus spp, 15.6% deuteromycetes, 15% yeasts and 4.1% members of the family mucoraceae. the resulting data indicate that microsporum canis was the most wide-spread species (73.7%) among the ...19911795730
in vitro nail invasion by pathogenic and non-pathogenic fungi under different culture conditions.data from the literature suggest that the nutritional environment can modify major metabolic functions of fungi and possibly their aggressivity towards keratinous structures. trichophyton rubrum (tr), microsporum canis (mc), scopulariopsis brevicaulis (sb), aspergillus fumigatus (af) and penicillium spec. (p) were inoculated on media of different nutritional value, in presence of nail fragments. the activity of the fungi was evaluated at two and four weeks for intensity and depth of invasion of ...19902103593
a case of fungal keratitis caused by scopulariopsis brevicaulis: treatment with antifungal agents and penetrating keratoplasty.a case of fungal keratitis caused by scopulariopsis brevicaulis following a penetrating eye injury is described. treatment with antifungal agents and keratoplasty resulted in a favourable outcome.19902168203
[effect of nitrogenous sources on the growth and morphogenesis of scopulariopsis brevicaulis bainier].growth and morphology of hyphae grown on a synthetic amino-acid supplemented medium were compared with those grown on a control medium. dry weight was lower in the amino-acids-containing medium and some ultrastructural changes were observed. cell wall thickness increase, and the cultures were seen to colonize the cellophane support. these observations may be related to a physiological requirement of this organism when grown on amino-acids of keratin.19892481996
fungi on the claws of buffalo and cow in egypt.the frequency of occurrence of fungi in 120 claw samples of buffalo and cow from different localities at assiut governorate was determined. thirty-seven species which belong to twenty genera were collected from the two substrates and the most common genera were chrysosporium (eleven species of chrysosporium were isolated). aspergillus and scopulariopsis. from the preceding genera chrysosporium sulfureum was common on cow claws but c. merdarium was slightly dominant on buffalo claws than on cow c ...19892482351
onychomycosis, tinea pedis and tinea manuum caused by non-dermatophytic filamentous fungi.over 4000 cases of fungal nail, sole and palm infection recorded during a three-year study period were investigated to determine the prevalence and significance of etiologic agents other than dermatophytes and yeasts. littman's oxgall agar, which permitted isolation of cycloheximide-sensitive species but restricted overgrowth by fast growing contaminants, was used to promote isolation of these disease agents. non-dermatophytic filamentous fungi made up 2.3% of the confirmed etiologic agents obta ...19892533665
invasive hyalohyphomycosis caused by scopulariopsis brevicaulis in a patient undergoing allogeneic bone marrow transplant.scopulariopsis brevicaulis is a common soil saprobic mould. occasionally, s. brevicaulis has been reported as an etiologic agent of human disease. the spectrum of human mycoses includes toenail infection, hypersensitivity pneumonitis, fungus ball formation in a preformed pulmonary cavity, and, most recently, documented deep tissue infections in immunocompromised hosts. a case of invasive hyalohyphomycosis of the great toe caused by s. brevicaulis is reported in an allogeneic bone-marrow transpla ...19892612131
fungal flora of poultry feedstuff ingredients.one hundred and ten samples representing five types of poultry feed ingredients were mycologically examined. these samples included soybean meal, ground maize, cotton-seed cake, wheat bran and fish meal (22 samples each). among the 73 mesophilic fungal species, aspergillus flavus, a. niger and a. fumigatus were the most dominant. a. terreus, a. flavipes, mucor circinelloides, scopulariopsis brevicaulis, penicillium chrysogenum, fusarium moniliforme and rhizopus stolonifer were found to be common ...19892621568
keratinophilic fungi from the duck nails in egypt.the mycoflora of one hundred and sixty of duck nail samples, collected from the duck farm, faculty of agriculture, assiut university, were examined. using the soil plate technique and sabouraud's dextrose agar, thirty six species appertaining to twenty genera of keratinophilic fungi were isolated. chrysosporium was the genus most frequently isolated (50% of the samples). aspergillus and penicillium occurred in low incidences (13.1 and 12.5% of total samples). trichophyton rubrum was found to col ...19892778647
keratinophilic fungi on sheep hairs from the west bank of jordan.the mycoflora of the hair in 285 sheep from the west bank of jordan was analysed and the frequency of occurrence and the relative importance value for different fungal species found were calculated. ninety six species which belong to 36 genera were isolated. forty one of these species were either well-known agents of animal and human mycoses (trichophyton verrucosum, t. mentagrophytes, microsporum nanum, m. canis, and others), or have been isolated from human and animal lesions (arthroderma cuni ...19892797114
[in vitro action spectrum of a new antifungal agent derived from morpholine: amorolfin].the minimal inhibitory concentrations of amorolfin against yeasts, dermatophytes, sporothrix schenckii and moduls were determined on sabouraud's dextrose agar by dilution test procedure (dixon's agar for malassezia). the yeasts (candida, torulopsis, trichosporon) present various susceptibility, mic ranged from 0.01 to 1 micrograms/ml-1 for sensible strains particularly malassezia (0.005-0.5 microgram/ml-1) ranged from 20 to 100 micrograms/ml-1 for resistant isolates. amorolfine is also effective ...19892797885
mycoflora of air-conditioners dust from riyadh, saudi arabia.using the hair baiting technique, 6 genera and 14 species were collected on sabouraud's dextrose agar from 37 dust samples from air-conditioners. the most common fungi were chrysosporium tropicum, c. indicum, c. keratinophilum, aspergillus flavus followed by acremonium strictum and scopulariopsis brevicaulis. using the dilution-plate method, 26 genera and 52 species were collected from 37 dust samples on glucose-(23 genera and 45 species) and cellulose-(18 genera and 34 species) czapek's agar at ...19883236219
scedosporium inflatum, an emerging pathogen.the salient morphologic and physiologic characteristics of 18 isolates of scedosporium inflatum, a newly reported human pathogen, were compared with those of the morphologically similar fungi scedosporium apiospermum, scopulariopsis brevicaulis, and scopulariopsis brumptii. the formation by s. inflatum of annelloconidia in wet clumps at the apices of annellides with swollen bases was found to be the most useful characteristic in differentiating this potential pathogen.19883356789
[in vitro spectrum of action of a new antifungal derivative of naftifin: terbinafin (sf 86-327)].terbinafine (sf 86-327) is a new antifungal agent derived from naftifine and effective by the oral route. we studied the in vitro antifungal activity of terbinafine (sf 86-327) against several pathogenic fungi responsible for human disease. tested pathogens included yeasts (candida), dermatophytes (microsporum, trichophyton, epidermophyton), molds (aspergillus, scopulariopsis) and dimorphic fungi (sporothrix schenkii). broth dilution (sabouraud) or agar dilution (sabouraud, kimmig) were used. 32 ...19863534767
[phospholipids of scopulariopsis brevicaulis]. 19863566095
dimorphism of scopulariopsis brevicaulis: morphogenesis of the mould to yeast phase.the dimorphism of scopulariopsis brevicaulus was induced in malt agar (oxoid), at 37 degrees c and 5-10% rate of co2. six cultures of s. brevicaulus were converted from hyphae to yeast-like cells by the following processes: one was that the hyphae formed intercalar and terminal chlamydoconidia-like cells. these cells increased in size, gained double contour and gave rise to budding cells. the other process was via conidia that assumed yeast characteristics. so, a transformation cycle m----y was ...19873696191
fungi on the hair of large mammals in egypt.the frequency of occurrence of fungi in 260 hair samples of dog, donkey and cow collected from veterinary medicine hospital of assiut university was determined. twenty-three species which belong to fifteen genera were collected. in low frequency, several dermatophytes (chrysosporium, microsporum, arthroderma and trichophyton) were found as well as some other fungal species pathogenic to man and animals (aspergillus fumigatus, stachybotrys chartarum, scopulariopsis brevicaulis and cephalosporium ...19863713793
effects of broiler litter volatiles and ammonia on fungal spore germination.the effects of broiler litter volatiles on spore germination of 12 fungal species were determined. the volatiles inhibited spore germination of all species except scopulariopsis brevicaulis. the inhibitory effect was fungistatic. the inhibitory volatile substances in litter were higher in built-up litter than in freshly used litter and were soluble in an acid solution. ammonia was identified by infrared analysis as a fungal inhibitory substance in litter. the effect of various concentrations of ...19863737506
[in vitro action of a new antifungal agent, naftifine, on dermatophytes].naftifine is a new antifungal agent derived from naphtalenemethane amine and highly active in vitro against dermatophytes. we studied this action against more than 100 strains belonging to 16 different species of the trichophyton, microsporum and epidermophyton genera. mics were determined in a liquid or solid medium using yma and ymb sabouraud broths. yeasts (candida, torulopsis) and certain molds such as scopulariopsis brevicaulis showed little susceptibility. in contrast, mics for dermatophyt ...19853911160
[occurrence of molds in airborne dusts in poultry farms].to reach conclusions in terms of industrial hygiene, mycological samples were taken in modern poultry farms between 1979 and 1981. sedimentation plates, the krotow slit collector and the spg-10 airborne dust sampler were used to determine the mould content of the air. the lowest germ counts were made in cage systems, while somewhat higher numbers were recorded among adult bids kept in the floor systems. unexpectedly high numbers of mould germs were found in the air of large poultry houses where ...19854082801
deep scopulariopsosis: a case report and sensitivity studies.a 36-year-old female was admitted to hospital for debridement of chronically inflamed tendon sheaths and adjacent tissues near the left ankle. despite antibiotic therapy and initial surgical interventions, the inflammation had progressed slowly over 16 months. histopathological examination of excised tissues in september 1973 revealed a chronic granulomatous inflammation of tendon sheaths and muscle. many branched hyphal segments, intercalary swollen cells, and a few conidia-like bodies were see ...19744139173
[onychomycoses caused by scopulariopsis brevicaulis]. 19654220924
[onychomycosis caused by scopulariopsis brevicaulis. presentation of a case]. 19684237979
an extracellular proteolytic enzyme from scopulariopsis brevicaulis. ii. hydrolysis of polyamino acids. 19724672254
[on the electrophoretic demonstration of isoenzymes of lactate dehydrogenase, malate dehydrogenase and glucose-6-phosphate dehydrogenase in dermatophytes, scopulariopsis brevicaulis and sporotrichum schenckii]. 19694977299
an extracellular proteolytic enzyme from scopulariopsis brevicaulis. i. purification and properties. 19715107013
[cytochemical demonstration of hydrolases and enzymes of carbohydrate metabolism in facultatively pathogenic molds (aspergillus niger, aspergillus fumigatus, scopulariopsis brevicaulis and verticillium cinnabarinum)]. 19685761200
[ketoconazole and onychomycosis].we have treated 48 cases of onychomycosis (of which 37 were caused by dermatophytes, 10 by yeasts and one by scopulariopsis brevicaulis) with 200 mg ketoconazole daily. we obtained recovery in 65 p. 100 of the cases of onyxis caused by dermatophytes and in 80 p. 100 of the cases of onychomycosis due to candida. the one patient presenting an infection with scopulariopsis brevicaulis recovered in 13 months. the average duration necessary to obtain complete recovery was 6 1/2 months for onychomycos ...19846089641
effect of treatment of soil with keratinaceous material on soil fungi.in the early periods of soil storage, the total number of fungi almost regularly and significantly increased with the concentration of keratinaceous material (ground buffalo hooves) between 1% and 10%. a concentration of 20% was stimulative after 7 days and became toxic after 15 days and remained so through the end of the experiment. with increase in the storage period, the beneficial effect of all concentrations was lost and in the case of high concentrations (5-20%) toxic ammonia was produced. ...19816171708
onychomycosis caused by scopulariopsis brevicaulis. 19816212045
scopulariopsis onychomycosis treated with natamycin.7 patients with scopulariopsis brevicaulis onychomycosis of the toe-nails were treated locally with 1% natamycin in 60% dimethylsulphoxide. after 3-5 months treatment the fungus could no longer be isolated from the nails, and at follow-up 15 months after the completion of the treatment, 2 patients reported permanent improvement of the nails and 3 a complete cure. in 1 patient the treatment was ineffective.19806444287
scopulariopsis brevicaulis in nails.scopulariopsis brevicaulis was demonstrated in 226 out of 5,600 patients examined for abnormal toe-nails. among 3,700 patients without onychomycosis s. brevicaulis was demonstrated as a contaminant in 2%. onychomycosis, present in 1,925 patients, was caused by s. brevicaulis in 6%, but 10% of these cases were mixed infections with dermatophytes. in the approximately 1,800 cases of onychomycosis due to other reasons, s. brevicaulis was a contaminant in 2%. a specific finding of s. brevicaulis on ...19806447633
[onychomycosis due to scopulariopsis brevicaulis (author's transl)]. 19806452674
[sensitivity of scopulariopsis brevicaulis (bainier) to antifungal agents]. 19846538645
[preliminary study of the chemical composition of crude membranes of scopulariopsis brevicaulis (bainier)].whole membrane constituents isolated from scopulariopsis brevicaulis in culture in vitro have been studied with respect to ultracytological and biochemical composition. the ratio of proteins to lipids is near 1. neutral lipids and phospholipids have been studied separately. the neutral lipids are triglycerids, diglycerids, free sterols and sterol esters, phospholipids are phosphatidylethanolamine and phosphatidylcholine.19826891749
deviation from the usual relationships between the temperature, the growth rate, the fatty acid composition and the lipid microviscosity of four different fungi (mucor mucedo, aspergillus ochraceus, scopulariopsis brevicaulis, achlya bisexualis. 19817306120
[the abnormal white line and hollow wall in horses, a comparative mycological study].there are few descriptions of an abnormal white line in the horse, and it is not known what causes this disorder. thirty horses and ponies with this disorder were examined mycologically, as were 30 horses and ponies with normal hooves. scopulariopsis brevicaulis was detected in 60% of the animals with an abnormal white line with or without hollow wall or brittle toe.19957482470
toxic gas generation from plastic mattresses and sudden infant death syndrome.microbial generation of toxic gases from antimony, arsenic, or phosphorus in compounds used as fire retardants in cot mattresses has been proposed as a cause of sudden infant death. to test this hypothesis, 23 polyvinyl chloride mattress samples from cot death cases were incubated on malt agar plates until good microbial growth was obtained. silver nitrate and mercuric chloride test papers were then inserted and the colour reactions recorded. the predominant organism, recovered from all mattress ...19957491046
sudden infant death syndrome: a possible primary cause.the hypothesis that poisoning by phosphines, arsines and stibines might be the primary cause of sudden infant death syndrome (sids) was investigated. most mattress materials contain phosphorus or antimony compounds as fire retardant additives. mattress materials in areas affected by the warmth and perspiration of the sleeping infant were found to be naturally infected by the fungus scopulariopsis brevicaulis which is thought to be capable of generating phosphines, arsines and stibines from mater ...19947523575
remarks on the appearance of "violine" on cantal cheese (a note).a mould, scopulariopsis brevicaulis was isolated from a cantal cheese. this mould was responsible for the "violine" phenomenon. it's optimum ph growth was about 7 and the mould was able to grow suitably at 10 degrees c, the temperature of cellar for cheese ripening. it was inhibited by high sodium chloride contents or low water activities.19957551713
surgical and long-term antifungal therapy for fungal prosthetic valve endocarditis.fungal prosthetic valve endocarditis is an uncommon but serious disease. we have developed a strategy of treatment that includes perioperative amphotericin b, radical debridement of infected tissue, reconstruction using biologic tissue when possible, and prolonged oral suppressive antifungal therapy.19957677477
[scopulariopsis brevicaulis otomycosis after tympanoplasty].we report a case of otomycosis due to scopulariopsis brevicaulis in a patient who has undergone tympanoplasty 3 months before. mycological finding led us to consider this fungus as the causative agent. whereas in vitro studies show a better efficiency of azole derivatives, cure was obtained with nystatine after two treatment failures in our patient.19947785936
scopulariopsis endocarditis associated with duran ring valvuloplasty.fungal endocarditis is rare and is usually caused by aspergillus and candida species. we present a patient with endocarditis caused by scopulariopsis brevicaulis. the patient had a history of mitral valve disease and, 1 year earlier, had undergone valvuloplasty with the placement of a prosthetic duran ring in the mitral valve position. s. brevicaulis was cultured from samples of a large vegetation on the mitral valve apparatus. the mitral valve was replaced with a st. jude mechanical prosthesis. ...19957787475
fungal propagules in house dust. ii. relation with residential characteristics and respiratory symptoms.as part of a case-control study on the relation between home dampness and respiratory symptoms of children, house-dust samples were collected from bedroom floors and mattresses in 60 homes in the netherlands. the house-dust samples were analyzed for the presence of fungal propagules by plating 30 mg of dust directly onto dg18 agar. a checklist and questionnaire were used to obtain information on the home characteristics and occupant behavior that may have an effect on the presence of fungal prop ...19947825721
fungal keratitis due to scopulariopsis brevicaulis in an eye previously suffering from herpetic keratitis.in the case reported, herpes virus i after having caused relapsing keratitis in an eye promoted the formation of a severe corneal ulcer caused by scopulariopsis brevicaulis, a saprophytic mycete found in soil, which only once has been described as the cause of keratitis in man. scopulariopsis was identified microscopically after culturing the conjunctival secretion on sabouraud dextrose agar medium, while dna probe tests confirmed the absence of herpes virus i. topical and oral administration of ...19947845651
[therapy with ciclopirox lacquer of onychomycoses caused by molds].60 patients, suffering from an onychomycosis produced by molds were treated for a maximum of 6 months with ciclopirox nail lacquer (8%). these molds determined by culture were scopulariopsis brevicaulis (51 x), aspergillus niger (6 x), aspergillus fumigatus (2 x) and hendersonula toruloidea. anamnesis gave no hints, why molds were the causing fungi of onychomycosis. the achieved mycological cure rate was determined with 90% (culture) respectively 85% (koh preparation). the local treatment with c ...19947854374
enzyme patterns of dermatophytes.exoenzymes produced by common dermatophytes, in addition to their ability to cause cutaneous inflammation, are thought to contribute to fungal spread. to investigate the patterns of enzymes released by common dermatophytes as well as scopulariopsis brevicaulis, the fungi were grown in liquid media containing either hair, stratum corneum, neopeptone or lipids, or in rpmi medium. enzymes recovered from the culture supernatants were compared using the api-zyme test. as a result, the widest range of ...19947935585
fungal keratitis caused by scopulariopsis brevicaulis: successful treatment with topical amphotericin b and chloramphenicol without the need for surgical debridement. 19947947559
ulcerous granulomatous cheilitis with lymphatic invasion caused by scopulariopsis brevicaulis infection.a 43-year-old man with ulcerous granulomatous cheilitis and submaxillary lymph node invasion caused by scopulariopsis brevicaulis infection is described. administration of itraconazole produced a dramatic and definitive cure. reported cases of deep mycosis caused by s. brevicaulis infection are also reviewed.19947962740
terbinafine in onychomycosis with involvement by non-dermatophytic fungi.sixty-five patients with onychomycosis involving the yeasts candida albicans or c. parapsilosis, or the mould scopulariopsis brevicaulis, were treated for up to 48 weeks with terbinafine 250 mg daily. at the end of therapy mycological and clinical cure rates were 70% and 54% for c. albicans, and 85% and 63% for c. parapsilosis, respectively. three out of seven s. brevicaulis infections were cured. within 6 months of therapy, relapses occurred in 45.5% of the cured patients in the case of c. albi ...19948186136
scopulariopsis brevicaulis skin lesions in an aids patient. 19938216996
survey of mycoflora and mycotoxins in egyptian soybean seeds.after four months in commercial storage, 100 soybean samples from different places of egyptian governorates were assayed for filamentous fungal growth at two incubation temperatures (28 and 45 degrees c). 73 species and 8 varieties belonging to 32 genera were isolated by the dilution plate method. at 28 degrees c, the common species were aspergillus flavus, a. fumigatus, a. niger and a. alutaceus, followed by a. terreus, penicillium chrysogenum, p. citrinum, mucor hiemalis, m. racemosus, emerice ...19938271157
cutaneous 'ringworm' lesions of scopulariopsis brevicaulis.scopulariopsis brevicaulis is a saprophytic fungus which is occasionally isolated as an apparent cause of toenail fungal infection, and which rarely has been reported as a cause of deep fungal granuloma. we report a case of skin infection with this organism, which was proved by culture of a pure isolate. the skin lesions had an annular ringworm appearance with pustules, they occurred initially at a site of minor injury, and they responded to treatment with terbinafine and itraconazole.19938286260
keratinophilic fungi in the antarctic environment.results of a study on the diffusion of keratinophilic fungi in an antarctic environment are given. nine soil samples collected from as many sites along the coast of ross sea, and six dust samples inside the italian scientific base were examined by direct inoculation and hair baiting methods for soil samples and plate dilution method for dust samples. as regards the variety of species isolated and the counting of the numbers of colonies, plate dilution method proved to be very effective. aspergil ...19938413499
azelaic acid has antimycotic properties in vitro.azelaic acid is a therapeutic agent with well-known antibacterial properties, but its antimycotic effect has not yet been investigated systematically. in this study we have used an agar dilution technique to test the inhibitory effect of azelaic acid upon common dermatophytes, scopulariopsis brevicaulis, candida albicans, candida glabrata and pityrosporum ovale. as a result, the growth of dermatophytes and s. brevicaulis was suppressed by 0.56% azelaic acid and that of p. ovale by 1%. by 4% azel ...19938435518
deep tissue infections caused by scopulariopsis brevicaulis: report of a case of prosthetic valve endocarditis and review.scopulariopsis brevicaulis is a saprophytic fungus that commonly causes onychomycosis but rarely causes deep tissue infection. to the best of our knowledge, this is the first reported case of endocarditis caused by s. brevicaulis. the infection persisted despite two aortic valve replacements, debridement, and prolonged therapy with several antifungal agents. the patient eventually died due to an acute myocardial infarction caused by ongoing prosthetic valve endocarditis. we review case reports o ...19958527566
plantar infection by scopulariopsis brevicaulis.a 42-year-old woman presented with a well-defined pruritic erythematous scaly plaque on the sole of each foot. the lesions, first noted about 15 years previously, were located in the medial plantar region and extended laterally. mycological study revealed infection by scopulariopsis brevicaulis. treatment with oral itraconazole led to temporary improvement, but the symptoms returned after treatment had been stopped (presumably due to re-infection from ungual foci). similar results were subsequen ...19968884156
onychomycosis due to scopulariopsis brevicaulis: clinical features and response to systemic antifungals.six cases of scopulariopsis onychomycosis, including four patients with onychomycosis exclusively caused by scopulariopsis brevicaulis and two patients with a mixed nail infection (s. brevicaulis + tricophyton rubrum and s. brevicaulis + t. interdigitale), are reported. four patients presented with a typical distal subungual onychomycosis characterized by subungual hyperkeratosis and onycholysis of the distal nail plate. in two patients, scopulariopsis infection produced a total dystrophic onych ...19968977686
itraconazole therapy is effective for pedal onychomycosis caused by some nondermatophyte molds and in mixed infection with dermatophytes and molds: a multicenter study with 36 patients.onychomycosis of the toenail caused by nondermatophyte molds alone or in combination with dermatophytes is difficult to eradicate with standard antifungal therapy.19979039163
onychomycosis in rome, italy.this report presents the results of a study conducted between 1985 and 1994 on onychomycosis observed in the city of rome. six thousand six hundred and eighty eight patients were examined during this period. among them 1,762 (26.3%) were affected by fungal nail infections. because the etiologic agents could not be isolated in 105 cases (6%), the results refer to 1,657 subjects (24.8% of the total), presenting with positive microscopic and cultural examinations. thirty eight patients (2.3%) had o ...19969144955
effect of lamisil and azole antifungals in experimental nail infection.onychomycosis is primarily caused by dermatophyte fungi but occasionally by yeasts and non-dermatophytic moulds. the aim of this study was to develop an in vitro model of nail invasion by dermatophytes, yeasts and non-dermatophytic moulds, and to provide an alternative system for studying the activity of different classes of antifungal drugs against fungi associated with onychomycosis. in the absence of extraneous nutrients, trichophyton mentagrophytes was seen in electron microscopy to degrade ...19979154398
species-specific selection on soil fungal population after olive mill waste-water treatment.soil was treated with olive mill waste water (omw) in order to study the effect of this agriculture waste on soil fungal population. changes in fungal composition were observed after soil pollution. in order to test omw selective pressure, growth kinetics of penicillium cyclopium, scopulariopsis brevicaulis and cladosporium cladosporioides were studied on solid media supplemented with different omw concentrations. s. brevicaulis and c. cladosporioides did not grow at omw concentration higher tha ...19979192466
posttraumatic fungal endophthalmitis resulting from scopulariopsis brevicaulis. 19979196940
unusual mould infection of the human stratum corneum.two atopic siblings presented with unilateral chronic scaly plantar lesions. histology revealed the presence of fungi with unusual morphological aspects. scopulariopsis brevicaulis and phoma spp., respectively, grew on repeated cultures. dermatophytes were absent. such opportunistic fungal infections of the stratum corneum are extremely rare.19979229340
study of onychomycosis in córdoba, spain: prevailing fungi and pattern of infection.from a total of 20,004 patients seen during two years, we carried out a mycologic nail investigation (direct microscopy and repeated cultures). ninety-three (43.2%) of the nails were judged to be infected by their clinical appearance. they fulfilled the laboratory criteria required to start antifungal treatment (isolation of the same fungus in culture on two consecutive occasions), but only in 64 cases (29.7%) was there a clinical and mycological recovery once antifungal treatment and follow up ...19979299751
[effect of domestic laundry processes on mycotic contamination of textiles].inadequately decontaminated clothing may be a source of reinfection following therapy of dermato- and onychomycoses. the objective of this study was to determine whether domestic laundering is suitable for cleansing mycotically contaminated garments. textile-samples contaminated with trichophyton rubrum, trichophyton mentagrophytes, candida albicans and scopulariopsis brevicaulis were washed in an ordinary washing machine at different temperatures. regardless of the textiles and detergents used, ...19979333615
can microorganisms convert antimony trioxide or potassium antimonyl tartrate to methylated stibines?no evidence could be found for the production, in culture, of methylated antimony compounds from water-insoluble or soluble antimony derivatives by the aerobes, scopulariopsis brevicaulis or bacillus sp. or by anaerobes associated with cot mattress materials. the study does not support the hypothesis that volatile organoantimony compounds are a cause of cot deaths. anaerobic cultures from a polluted pond generated trimethylstibine from potassium antimonyl tartrate.19979372631
fungal volatilization of arsenic and antimony and the sudden infant death syndrome.fungal volatilization of antimony and other group vb elements has been proposed to have a causal role in the sudden infant death syndrome (sids; cot death). the ability of fungi to produce volatile arsenic and antimony compounds in pure culture was examined using scopulariopsis brevicaulis, reported as an inhabitant of pvc cot mattress covers, and phaeolus schweinitzii, a wood decay fungus known to be a good volatilizer of arsenic. volatile arsenic compounds were detected from all cultures grown ...19989465397
nondermatophyte causes of onychomycosis and superficial mycoses.compared to dermatophytes, nondermatophytes that may cause distal and lateral subungual onychomycoses are aspergillus species, acremonium species, fusarium oxysporum and scopulariopsis brevicaulis. white superficial onychomycosis may be caused by nondermatophyte species, for example, acremonium species, aspergillus terreus, other aspergillus species and fusarium oxysporum. nondermatophyte molds such as scopulariopsis brevicaulis may uncommonly result in cutaneous infections. scytalidium dimidiat ...19969504061
synthesis, antimicrobial activity and bleaching effect of some reaction products of 4-oxo-4h-benzopyran-3-carboxaldehydes with aminobenzothiazoles and hydrazides.the synthesis of the biologically active novel systems derived from reaction of 3-formylchromones with three types of amino derivatives, 6-r2-2-aminobenzothiazoles, 6-amino-2-r3-thiobenzothiazoles and hydrazide derivatives (derived from cyanoacetic, isonicotine, salicylic and gallic acids) was carried out. the structures of the prepared compounds have been proved by elemental analysis, 1h nmr and ir spectra. antimicrobial activity was studied against the following microorganisms--bacteria g+ (st ...19989639869
granulomatous skin infection caused by scopulariopsis brevicaulis.a 14-year-old girl with a granulomatous infection of the cheek caused by scopulariopsis brevicaulis is described. treatment successively consisted of itraconazole and/or terbinafine for 19 months, after which clinical and mycologic cure seemed to be obtained. however, a relapse occurred 10 months later.19989703155
aspergillus versicolor as cause of onychomycosis: report of 12 cases and susceptibility testing to antifungal drugs.onychomycoses caused by opportunistic moulds are not well understood, and many are due to scopulariopsis brevicaulis and other species. aspergillus versicolor is not documented as an etiological agent in most studies. we have found an increasing prevalence of this species which is involved in 5.8% of all fungal infections of toe nails.19989731962
saprophytic and cycloheximide resistant fungi isolated from golden hamster.healthy hair samples from golden hamsters were examined for the presence of dermatophytes and non-dermatophytes using baiting technique and direct inoculation. thirty-four species and 2 varieties attributed to 17 genera were recovered. paecilomyces variotii (isolated from 84.4% of the examined hair) and aspergillus niger (81.3%) were the more frequent isolates on sabouraud's dextrose agar (sda) without cycloheximide. our results have clearly demonstrated that the hair of hamster was free from tr ...19989768288
reduction in the growth of non-dermatophyte moulds by itraconazole: evaluation by corneofungimetry assay.the activity of itraconazole against fungi of dermatological importance was studied using corneofungimetry performed on four test organisms: aspergillus flavus, fusarium oxysporum, scopulariopsis brevicaulis and scytalidium dimidiatum. the human stratum corneum used in the bioassay was harvested from healthy volunteers and from patients undergoing treatment with itraconazole 200 mg daily for at least 2 weeks. a fungal mycelium grew on all untreated stratum corneum samples within 1 week. the patt ...19989919887
comparison of e-test and broth microdilution methods for antifungal drug susceptibility testing of molds.we compared the e test with a broth microdilution method, performed according to national committee for clinical laboratory standards document m27-a guidelines, for determining the in vitro susceptibilities of 90 isolates of pathogenic molds (10 absidia corymbifera, 10 aspergillus flavus, 10 aspergillus fumigatus, 10 aspergillus niger, 10 aspergillus terreus, 10 exophiala dermatitidis, 10 fusarium solani, 10 scedosporium apiospermum, 5 scedosporium prolificans, and 5 scopulariopsis brevicaulis). ...199910203509
[fungal flora in chicken stalls and its etiopathogenic importance for humans and animals].in order to find out the mycoflora prevailing in chicken pens, and to appreciate the health hazards for employees (incl. veterinarians) and animals, twenty litter samples and 6 sedimented dust trials were analysed mycologically. the following results were found: bedding and dust samples all contained between 3.57 and 1.30 x 10(7) c.f.u./g dw. the commonest fungus is a. fumigatus with 3.41 x 10(4) - 1.30 x 10(7) c.f.u./g dw in bedding and 2.70 x 10(5) - 3.30 x 10(6) c.f.u./g dw in sedimented dust ...199910209909
in vitro activity of syn-2869, a novel triazole agent, against emerging and less common mold pathogens.the in vitro activity of syn-2869 was compared with that of amphotericin b and itraconazole. mics for 100 isolates of pathogenic molds belonging to 12 species were determined by a broth microdilution adaptation of the method recommended by the national committee for clinical laboratory standards. syn-2869 and itraconazole showed comparable, good activity against the dematiaceous molds cladophialophora bantiana, cladophialophora carrionii, exophiala dermatitidis, fonsecaea pedrosoi, phialophora p ...199910223947
onychomycosis in lahore, pakistan.onychomycosis, a common nail disorder, is caused by yeasts, dermatophytes, and nondermatophyte molds. these fungi give rise to diverse clinical presentations. the present study aimed to isolate the causative pathogens and to determine the various clinical patterns of onychomycosis in the population in lahore, pakistan.199910487448
onychomycosis caused by nondermatophytic molds: clinical features and response to treatment of 59 cases.nail invasion by nondermatophytic molds (ndm) is considered uncommon with prevalence rates ranging from 1.45% to 17. 6%.200010642676
recurrent subcutaneous infection due to scopulariopsis brevicaulis in a liver transplant recipient.we describe a case of recurrent scopulariopsis brevicaulis subcutaneous infection, which occurred 6 years after the patient underwent liver transplantation. combined surgery and long-term oral therapy with terbinafine resulted in a favorable outcome, although this is not the rule in the previously reported s. brevicaulis infections in immunocompromised patients.200010816153
influence of fowl uropygial gland and its secretory lipid components on the growth of skin surface fungi of fowl.fungal species, which were shown to colonize consistently on the skin surface of the breast region of adult (1 year old) white leghorn fowl, were identified as aspergillus sydowii, a. tamarii, a. rugulosus and absidia corymbifera. of these, a. sydowii and a. tamarii were the dominant forms. two species of fungi, namely, aspergillus niger and scopulariopsis brevicaulis were shown to be present in the cultures of the scrubbings from breast skin surface after 60 days of captivity of the fowls. exti ...199910865889
activity of terbinafine against serious fungal pathogens.although primarily indicated for dermatophyte infections, the allylamine terbinafine is active in vitro against a broad spectrum of filamentous and dimorphic fungi, in most cases with a primary fungicidal action. using the standard nccls m27-a assay, recent studies confirmed the high activity of terbinafine against dematiaceous fungi and other medically important moulds such as aspergillus and penicillium marneffei. terbinafine displayed a geometric mean mic of 1.4 micrograms/ml against candida ...199910865917
cloning and sequencing of an endoglucanase gene from scopulariopsis brevicaulis tof-1212, and its expression in saccharomyces cerevisiae.the egi gene, encoding a major endoglucanase (egi) of scopulariopsis brevicaulis tof-1212, was cloned and sequenced. the eglgene consisted of 868 bp with one intron and encoded a protein of 229 amino acids with a calculated molecular mass of 22,392 daltons. the egi was assigned to a family 45 of glycosyl hydrolases and showed high similarity with other fungal endoglucanases, especially with those of humicola grisea and fusarium oxysporum, on the basis of hydrophobic cluster analysis. the egi gen ...200010923796
general assessment of the influence of a municipal landfill site and environmental factors on the occurrence of keratinolytic fungi in soil.the study was to generally determine the influence of a municipal landfill site and environmental factors on the distribution of keratinolytic fungi in soil. the landfill site in sosnowiec was selected for examination. keratinolytic fungi occurred abundantly in soils of the landfill site examined and its surrounding area. of 495 soil samples (petri dishes) examined, 379 (76.56%) were found to be positive for keratinolytic fungi. altogether, 1131 strains from 26 species were isolated from the sam ...200010959197
scopulariopsis brevicaulis: a keratinophilic or a keratinolytic fungus?the morphologic expression of human hair and nail invasion in vitro by scopulariopsis brevicaulis isolates was studied by light microscopy on whole material and on semi-thin sections, and also by scanning and transmission electron microscopy. only three isolates of the nine that were examined were keratinolytic, capable of both attacking keratinic substrates and demolishing their keratin. the process showed all the characteristic of enzymatic digestion and was in agreement with the biochemical a ...200011036398
antimony biomethylation by scopulariopsis brevicaulis: characterization of intermediates and the methyl donor.the filamentous fungus scopulariopsis brevicaulis biomethylates inorganic antimony(iii) compounds to trimethylstibine, that can be detected in culture headspace gases. dimethylantimony and trimethylantimony species have been detected in the medium of these cultures, but the origin of these species was controversial. we now show that the dimethylantimony species is a true intermediate on the pathway to trimethylstibine (rather than arising from trimethylstibine oxidation or as an analytical artif ...200011057610
occurrence of itraconazole-tolerant micromycetes in the soil and food products.unexpected pathogens from the environment represent considerable risk for humans with impaired health. we examined the occurrence of itraconazole tolerant micromycetes in soil and in maize products. five concentrations of itraconazole (2.5-12.5 micrograms/ml) selected according to known treatment schedules for human patients were incorporated into sabouraud agar with chloramphenicol and rose bengal and diluted samples were inoculated onto the agar surface. after 7-d growth at 22 degrees c coloni ...199911097027
keratinopathogenic mould fungi and dermatophytes in healthy and diseased hooves of horses.specimens of hoof horn from 187 horses were examined for a possible relationship between clinically affected hooves and the occurrence of pathogenic fungi. specimens were taken from the coronary band and from the stratum externum and medium of the coronary horn and transferred on to sabouraud dextrose agar, with and without cycloheximide, and incubated at 28 degrees c. dermatophytes and mould fungi were identified by their macroscopic and microscopic characteristics. the 732 isolates could be as ...200011128074
[subcutaneous mycosis due to scopulariopsis brevicaulis in an immunocompromised patient].scopulariopsis brevicaulis is a causal agent of onchomycosis. we report the unusual clinical manifestations caused by this opportunist fungus.200111275588
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