Publications

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chloriolide, a 12-membered macrolide from chloridium virescens var. chlamydosporum (nrrl 37636).a new 12-membered macrolide (chloriolide; 1) was obtained from solid-substrate fermentation cultures of chloridium virescens var. chlamydosporum that was originally isolated from decayed wood. the structure of 1 was determined by analysis of 1d nmr, 2d nmr, and ms data and confirmed by x-ray crystallographic analysis. the absolute configuration of 1 was assigned by application of the modified mosher method using the (r)- and (s)-mtpa derivatives of a rearrangement product obtained under standard ...200616643041
total synthesis of (+)-chloriolide.the first total synthesis of (+)-chloriolide, a 12-membered macrolide from chloridium virescens (var. chlamydosporum), was accomplished in a longest linear sequence of 20 steps from commercial materials in 7% overall yield.201020165786
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