| sporotrichosis caused by sporothrix mexicana, portugal. | | 2011 | 22000393 |
| emergence of pathogenicity in the sporothrix schenckii complex. | sporothrix schenckii sensu lato is a complex of thermally dimorphic species whose natural habitats are soil and plant materials. however, the traumatic implantation of the species into human skin is traditionally thought to be the route leading to the fungal disease sporotrichosis. the complex contains sporotrhix mexicana, s. globosa, s. brasiliensis, s. luriei, in addition to s. schenckii sensu stricto. in this study we evaluated the differences among these species relative to their frequency i ... | 2013 | 22989196 |
| an outbreak of lymphocutaneous sporotrichosis among mine-workers in south africa. | the largest outbreak of sporotrichosis occurred between 1938 and 1947 in the gold mines of witwatersrand in south africa. here, we describe an outbreak of lymphocutaneous sporotrichosis that was investigated in a south african gold mine in 2011. | 2015 | 26407300 |
| sporothrix chilensis sp. nov. (ascomycota: ophiostomatales), a soil-borne agent of human sporotrichosis with mild-pathogenic potential to mammals. | a combination of phylogeny, evolution, morphologies and ecologies has enabled major advances in understanding the taxonomy of sporothrix species, including members exhibiting distinct lifestyles such as saprobes, human/animal pathogens, and insect symbionts. phylogenetic analyses of its1/2 + 5.8s sequences split sporothrix genus in two well-defined groups with dissimilar ecologies. species embedded in the sporothrix schenckii complex are frequently agents of human and animal sporotrichosis, and ... | 2016 | 26781380 |
| genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis. | sporotrichosis is a chronic subcutaneous mycosis of humans and animals, which is typically acquired by traumatic inoculation of plant material contaminated with sporothrix propagules, or via animals, mainly felines. sporothrix infections notably occur in outbreaks, with large epidemics currently taking place in southeastern brazil and northeastern china. pathogenic species include sporothrix brasiliensis, sporothrix schenckii s. str., sporothrix globosa, and sporothrix luriei, which exhibit diff ... | 2014 | 24755107 |
| development and optimization of a new maldi-tof protocol for identification of the sporothrix species complex. | accurate species identification of the sporothrix schenckii complex is essential, since identification based only on phenotypic characteristics is often inconclusive due to phenotypic variability within the species. we used matrix-assisted laser desorption ionization time-of-flight mass spectrometry (maldi-tof ms) for species identification of 70 environmental and clinical isolates of the sporothrix complex. a reference database was established for maldi-tof ms-based species identification accor ... | 2015 | 25561427 |
| molecular identification of the sporothrix schenckii complex. | sporothrix schenckii, an ascomycetous dimorphic organism that for over a century was recognized as the sole agent of sporotrichosis, a subcutaneous mycosis with a worldwide distribution. however, it has been proposed, based on physiologic and molecular aspects, that s. schenckii is a complex of distinct species: sporothrix brasiliensis, sporothrix mexicana, sporothrix globosa, s. schenckii sensu strictu, sporothrix luriei, and sporothrix albicans (formerly sporothrix pallida). human disease has ... | 2014 | 24270070 |
| sporotrichosis. | sporotrichosis is the most common subcutaneous mycosis. it is usually acquired by traumatic inoculation, and it is caused by one of the species of the sporothrix schenckii complex. more than 6 species, such as s schenckii sensu stricto, sporothrix brasiliensis, sporothrix globosa, sporothrix mexicana, and sporothrix albicans, have been identified by molecular techniques. the most common presentation is cutaneous disease, which is classified into fixed and lymphocutaneous forms. osteoarticular, p ... | 2013 | 22682194 |
| molecular identification of sporothrix species involved in the first familial outbreak of sporotrichosis in the state of espírito santo, southeastern brazil. | sporotrichosis is a widespread subcutaneous mycosis caused by the dimorphic fungi now known as the sporothrix schenckii complex. this complex is comprised of at least six species, including sporothrix albicans, sporothrix brasiliensis, sporothrix globosa, sporothrix luriei, sporothrix mexicana and s. schenckii. cases of sporotrichosis have significantly increased in brazil over the past decade, especially in the state of rio de janeiro (rj), where an epidemic among cat owners has been observed. ... | 2013 | 24141957 |
| different virulence levels of the species of sporothrix in a murine model. | a comparative study on the experimental pathogenicity of five species of sporothrix of clinical interest, sporothrix albicans, sporothrix brasiliensis, sporothrix globosa, sporothrix mexicana, and sporothrix schenckii sensu stricto, was performed using an immunocompetent murine model. two strains of each species and two levels of inoculum for each strain (2x10(7) and 2x10(4) conidia/animal) were tested by intravenous inoculation of mice (ten per group). mortality was caused by the low inoculum o ... | 2009 | 19624508 |
| susceptibility of species within the sporothrix schenckii complex to a panel of killer yeasts. | the sporothrix schenckii complex is the etiologic agent of sporotrichosis, a subacute or chronic mycosis which can affect humans and animals. killer yeasts have been used in the medical field for development of novel antimycotics and biotyping of pathogenic fungi. the action of 18 killer yeasts on the growth of 88 characterized s. schenckii, sporothrix globosa, sporothrix brasiliensis, and sporothrix mexicana clinical and environmental isolates was evaluated. killer studies were performed on pet ... | 2014 | 23686831 |
| immunoproteomic analysis reveals a convergent humoral response signature in the sporothrix schenckii complex. | sporotrichosis is a polymorphic disease that affects both humans and animals worldwide. the fungus gains entry into a warm-blooded host through minor trauma to the skin, typically by contaminated vegetation or by scratches and bites from a diseased cat. cellular and humoral responses triggered upon pathogen introduction play important roles in the development and severity of the disease. we investigated molecules expressed during the host-parasite interplay that elicit the humoral response in hu ... | 2015 | 25434489 |
| sporothrix schenckii complex and sporotrichosis, an emerging health problem. | sporothrix schenckii, now named the s. schenckii species complex, has largely been known as the etiological agent of sporotrichosis, which is an acute or chronic subcutaneous mycosis of humans and other mammals. gene sequencing has revealed the following species in the s. schenckii complex: sporothrix albicans, sporothrix brasiliensis, sporothrix globosa, sporothrix luriei, sporothrix mexicana and s. schenckii. the increasing number of reports of sporothrix infection in immunocompromised patient ... | 2011 | 21162638 |
| two-dimensional gel electrophoresis data for proteomic profiling of sporothrix yeast cells. | sporotrichosis is a chronic infection of the skin and subcutaneous tissues of human and other mammals caused by a complex of cryptic dimorphic fungi in the plant-associated order ophiostomatales. with major differences between routes of transmission, sporothrix infections are emerging as new threat in tropical and subtropical areas, particularly in form of outbreaks. the mechanisms underlying the pathogenesis and invasion of sporothrix spp. are still poorly understood and many virulence factors ... | 2015 | 26217702 |
| phylogeography and evolutionary patterns in sporothrix spanning more than 14 000 human and animal case reports. | pathology to vertebrate hosts has emerged repeatedly in the order ophiostomatales. occasional infections have been observed in sporothrix mexicana at a low level of virulence, while the main pathogenic species cluster in a derived clade around s. schenckii s.str. in this paper, phylogeny and epidemiology of the members of this clade were investigated for 99 clinical and 36 environmental strains using four genetic loci, viz. rdna its and partial cal, tef1, and tef3; data are compared with amplifi ... | 2015 | 26823625 |