| antifungal properties of alpha,omega-alkanedicarboxylic acids and their dimethyl esters. | thirteen alpha, omega-alkanedicarboxylic acids (c2-c12, c14, and c16) and their dimethyl esters were tested against aspergillus niger, trichoderma viride, and myrothecium verrucaria in sabourauc dextrose agar at ph 4.0 and 5.6. toxicity to canadida albicans, trichophyton mentagrophytes, and mucor mucedo was determined in the same medium at ph 5.6 and 7.0 in the absence and presence of 10% beef serum. the dicarboxylic acids possessed very poor to no antifungal activity against all six fungi. the ... | 1976 | 9194 |
| pigment formation by trichophyton rubrum: differentiation between t. rubrum and t. mentagrophytes on serum albumin agar (author's transl). | on serum albumin agar (bovine albumin) with initial ph-values of 5.0-6.0, trichophyton rubrum showed a yellow pigmentation, and on the same medium with an initial ph-value of 7.0, a red pigmentation. strains of trichophyton mentagrophytes have never shown pigmentation until now, the scarce growth (submerged) of t. rubrum on serum albumin agar is associated with a pigment formation that may be used for diagnostic purposes. it could be read within 3-7 days. serum albumin agar with the initial ph-v ... | 1977 | 15390 |
| factors affecting germination of trichophyton mentagrophytes arthrospores. | nutritional and environmental factors affecting germination of trichophyton mentagrophytes arthrospores were investigated. germination of dormant arthrospores occurred only in rich complex media such as sabouraud dextrose broth or vitamin-free casamino acids. however, once activated, arthrospores were able to germinate under wide ranges of ph (5.5 to 8.0, optimal 6.5) and temperature (20 to 39 degrees c, optimal 37 degrees c) in the presence of certain single amino acids or oligopeptides known t ... | 1977 | 21851 |
| antifungal properties of 2-alkynoic acids and their methyl esters. | thirteen 2-alkynoic acids and their methyl esters (c3--c12, c14, c16, and c18) were tested against aspergillus niger, trichoderma viride, and myrothecium verrucaria in sabouraud dextrose agar at ph 4.0 and 5.6. toxicity to candida albicans, trichophyton mentagrophytes, and mucro mucedo was determined in the same medium at ph 5.6 and 7.0 in the absence and presence of 10% beef serum. the fungitoxicity of the acids was influenced by chain length, ph of the medium, and absence or presence of adsorb ... | 1978 | 26458 |
| serum-albumin agar used as slant for the differentiation between trichophyton rubrum and trichophyton mentagrophytes: specific reg pigmentation of t. rubrum. | trichophyton rubrum strains freshly isolated from clinical material exhibited red pigment formation within 7 days at 26 degrees c on slant serum-albumin agar, initial ph 7.0. in trichophyton mentagrophytes strains this phenomenon could not be observed. since in the case of t. rubrum, yellow pigmentation will appear at an initial ph of 5.0, the use of initial ph values of 7.0 and 5.0 is recommended for diagnostic application of slant serum-albumin agar. | 1978 | 29418 |
| effects of deferoxamine methanesulfonate on trichophyton mentagrophytes. | deferoxamine methanesulfonate (desferal), an iron chelator, inhibited germ tube formation and growth of trichophyton mentagrophytes in a microculture assay. a 50% reduction of germ tube formation required desferal at 5 mg/ml and a 50% reduction of growth required 1.5 mg/ml. growth was almost completely inhibited with 50 and 100 mg/ml. also, desferal at 100 mg/ml inhibited further elongation when added to short hyphae (ii and 21 micrometer), but showed less inhibitory effects when added to long h ... | 1979 | 43597 |
| an evaluation of delayed hypersensitivity in guinea pigs to various trichophytin preparations. | guinea pigs immunized with mycelium from trichophyton mentagrophytes in freund's complete adjuvant were tested intradermally with the following trichophytin preparations: tri extracted by ethylene glycol, trii extracted by phenol and trii, a commercially obtained preparation fromsächsisches serumverk kg. in our experience, tri was found to be superior to the other preparations. it showed signifiicant delayed skin reactions in all sensitized animals and none in the controls. lymphocyte stimulatio ... | 1976 | 60024 |
| studies of the antigenic structure of trichophyton rubrum, trichophyton mentagrophytes, microsporon canis, and epidermophyton floccosum by crossed immuno-electrophoresis. | by means of crossed immuno-electrophoresis, 35 antigens of t. rubrum, 26 of t. mentagrophytes, 35 of m. canis, and 25 of e. floccosum have been demonstrated. tandem crossed immuno-electrophoresis has revealed two antigens common to t. rubrum and the other species, which, however, differ within the species. no common antigens have been demonstrated between t. mentagrophytes, m. canis, and e. floccosum. the technique for preparation of extracts and production of immune serum is described, and the ... | 1976 | 60875 |
| control of exocellular proteases in dermatophytes and especially trichophyton rubrum. | the production of proteases was investigated during growth of dermatophytic fungi with special emphasis on trichophyton rubrum. exogenous glucose suppressed elastase production in all dermatophytes examined. the production of protease active guinea pig hair in keratin-salts broth by microsporum gypseum. trichophyton mentagrophytes and t. rubrum was also suppressed by glucose. various carbohydrates added to keratin-salts broth curtailed protease production by t. rubrum as did individual amino aci ... | 1979 | 94467 |
| glucose and phosphorus utilization by two dermatophytes. | trichophyton mentagrophytes and aspergillus fumigatus dissimilated glucose through emp pathway. oxygen and inorganic phosphorus were found to control the rate and extent of glucose metabolism. | 1979 | 94752 |
| [dermatomycosis of the nilgai antelope (boselaphus tragocamelus) caused by the dermatophyte trichophyton mentagrophytes]. | the authors described a dermal lesion in seven antelopes of the species boselaphus tragocamelus (pallas 1776), kept in a zoo-park. mycological examination revealed the dermatophyte trichophyton mentagrophytes (robin) blanchard 1896 as the causative agent of the lesion. the clinical picture of the dermatophytosis was manifested by a non-inflammatory desquamation of the epidermis with focal hair shedding. the lesions, mostly localized on the heads of the animals affected, were successfully treated ... | 1978 | 97843 |
| immunological cross-reactivity between a glycoprotein isolated from trichophyton mentagrophytes and human isoantigen a. | a glycoprotein isolated from the cell wall of trichophyton mentagrophytes was assessed for its cross-reaction with human blood group isoantigens. rabbit antiglycoprotein antibodies agglutinated human erythrocytes of blood groups a1 and a2, and precipitated blood group substance a in agarose gels. erythrocytes of blood group b were only slightly agglutinated, and o(rho+) and o(rho-) erythrocytes were not. additionally, the glycoprotein was shown to specifically inhibit isoagglutination of erythro ... | 1979 | 105052 |
| [on the antimicrobial activity of propolis and propolis constituents (author's transl)]. | after a survey of the literature on the antimicrobial activity of the bee product propolis, the authors discuss their own findings as compared to the chemotherapeutical agents streptomycin, oxytetracycline, chloramphenicol, nystatin, griseofulvin and sulphamerazine. according to the results obtained by testing 25 isolated constituents on bacillus subtilis, staphylococcus aureus, candida albicans and trichophyton mentagrophytes, the antimicrobial properties of this mixture of natural substances a ... | 1979 | 108687 |
| fungal glycosidases. v. purification and properties of an extracellular exo-(1 leads to 3)-beta-d-glucosidase from trichophyton mentagrophytes. | | 1979 | 117909 |
| [localization of solitary dermatophytic lesions in man]. | the occurrence of three causative organisms of the so called intertriginous dermatophytoses--epidermophyton floccosum, trichophyton mentagrophytes var. interdigitale and t. rubrum--was compared according to the localization of the lesions. the differentiation of invasion into solitary and combined sites showed a prevalence of e. floccosum in solitary lesions and t. rubrum in combined lesions. in t. mentagrophytes var. interdigitale, the frequency of occurrence of both types of the lesions was ap ... | 1975 | 126977 |
| [trichophyton mentagrophytes var. erinacei infection contracted from a hedgehog]. | occasionally the hedgehog (erinaceus europaeus) is infected by trichophyton mentagrophytes (robin) blanchard var. erinacei. this zoophilic dermatophyte may cause a difficult human phlegmatic trichophytia infection. the thread-fungus grows on the usual culture-medium with a clear-white surface without radius-folding. the lower surface of the culture shows a typical brillant-yellow colour. microscopically the fungus presents abundant microconidia formation and a few distinct macroconidia. cross-br ... | 1979 | 155666 |
| culture medium alkalinization by dermatophyes. (influence of time and temperature of incubation). | 95 dermatophyte strains (12 of trichophyton mentagrophytes, 12 of t. tonsurans, 11 of t. rubrum, 12 of t. megninii, 12 of t. violaceum, 2 of t. schoenleinii, 1 of t. soudanense, 12 of m. canis, 8 of microsporum gypseum, 1 of m. ferrugineum and 12 of epidermphoyton floccosum). 1 of aspergillus niger, 1 of a. ochraceus, 1 of paecilomyces sp., 1 of penicillium sp. and 1 of candida albicans were grown in sabouraud liquid medium for the study of ph variation over 6 weeks at room temperature and after ... | 1975 | 238130 |
| [randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)]. | trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ... | 1975 | 239503 |
| fungitoxicity of 1,4-naphthoquinones to candida albicans and trichophyton mentagrophytes. | twenty-one substituted 1,4-naphthoquinones and five 8-quinolinols and copper(ii) chelates were tested for antifungal activity against candida albicans and trichophyton mentagrophytes. compounds containing electron-releasing or weak electron-withdrawing groups in the 2 and 3 positions of the 1,4-naphthoquinone ring were the most active against c. albicans at ph 7.0 in the presence of beef serum in the following order: 2-ch3o = 2,3-(ch3o)2 greater than 2-ch3 greater than 2-ch3s greater than 2-nh2 ... | 1975 | 241479 |
| [new peptide antigen from trichophyton mentagrophytes mycelia (author's transl)]. | | 1979 | 317320 |
| synthesis and antifungal properties of certain 7-alkylaminopyrazolo[1,5-a]pyrimidines. | a series of 7-alkylaminopyrazolo[1,5-alpha]pyrimidines (5-25) and one 7-alkylthiopyrazolo[1,5-alpha]pyrimidine (4) were synthesized from the corresponding 7-chloro precursors 3, which were prepared in turn from the 7-hydroxy analogues 2, obtained via condensation of 3-aminopyrazoles with acetoacetate esters, malonate esters, or acetylenedicarboxylate ester. compounds 4-25 were found to inhibit trichophyton mentagrophytes (in vitro). the degree of inhibition increased with increasing 7-alkylamino ... | 1977 | 319236 |
| antifungal properties of 2-bromo-3-fluorosuccinic acid esters and related compounds. | twelve esters (c1-c6) of erythro- and threo-2-bromo-3-fluorosuccinic acid and related compounds were tested for antifungal activity against candida albicans, aspergillus niger, mucor mucedo, and trichophyton mentagrophytes at ph 5.7 and 7.0 in the absence and presence of 10% beef serum in sabouraud dextrose agar. at ph 7.0 in the presence of 10% beef serum, no consistent pattern in the fungitoxicity of the erythro- and threo-2-bromo-3-fluorosuccinate esters was seen. increasing the length of the ... | 1977 | 321785 |
| primary amides of bis-(2-carboxyphenyl)-disulfides with antimycotic activity]. | a series of bis-amides of 2,2'-dicarboxydiphenyldisulfides with monosubstituted n-alkyl groups (substances i leads to xxvi) or n-aralkyl groups (substances xxvi leads to xlii) was prepared and examined for in vitro antifungal activity. the substances were obtained by condensing the chloride of 2,2'-dicarboxydiphenyldisulfide with suitable amines. the fungistatic activity of the products was tested in vitro against the following four strains: candida albicans, candida tropicalis, saccharomyces ce ... | 1977 | 330218 |
| amino acid analogs iv:4-fluoroisoleucine. | 4-fluoroisoleucine was produced by ammonolysis of 2-bromo-4-fluoro-3-methylpentanoic acid, which resulted from the bromofluorination of 4-methyl-2-pentenoic acid. it did not inhibit plasmodium berghei in mice at 640 mg/kg and was not toxic to the animals. the fluoroamino acid inhibited aspergillus niger, trichoderma viride, myrothecium verrucaria, trichophyton mentagrophytes, and mucor mucedo in czapek solution agar at a concentration between 10(4) and 10(3) microgram/ml. growth of escherichia ... | 1978 | 347050 |
| determination of biogenous amines in fungus-cultures (candida albicans, trichophyton mentagrophytes, trichophyton rubrum and microsporum canis) by thin-layer chromatography and mass-spectrometry. | | 1978 | 366401 |
| [s-acylderivatives of thiosalicylamides with antifungal activity. i]. | a series of s-acylderivatives of n-ethylthiosalicylamide (substances i leads to xxiii) was prepared and tested for in vitro antifungal activity. the substances, not previously reported, were prepared by the reaction of 2-mercapto-n-ethylbenzamide with suitable acylating agents. the fungistatic activity of the prepared products was tested in vitro against candida albicans and trichophyton mentagrophytes. the results given in table i show that the s-acylderivatives of n-ethylthiosalicylamides have ... | 1978 | 367811 |
| [s-acyl derivatives of thiosalicylamides having antifungal activity. ii]. | some s-acyl derivatives of n-alkylthiosalicylamides [table i: substances (i leads to xxxi)] were prepared and tested for antifungal activity. the substances, most of which had not been previously reported, were prepared by condensation of 2-mercapto-n-alkylbenzamides with suitable acylating agents. the antifungal activity of the compounds was tested in vitro against candida albicans and trichophyton mentagrophytes. for some compounds the was tested activity against the above strains fungicidal, ... | 1978 | 369885 |
| dermatophytes in a population of bank voles and woodmice. | a population of bank voles (clethrionomys glareolus) and wood mice (apodemus sylvaticus) inhabiting an oak wood in somerset was examined for dermatophytes at monthly intervals for 2 years. the marked animals were frequently retrapped, allowing a study of host fungus relationship over a period of time. microsporum persicolor (sabouraud) guiart er grigorakis and trichophyton mentagrophytes (robin) blanchard were isolated from both animal species, but m. persicolor predominated in bank voles and t. ... | 1978 | 375097 |
| in vitro survival of human pathogenic fungi in seawater. | the survival of propagules from 4 pathogenic fungi, trichophyton mentagrophytes, trichosporon cutaneum, candida albicans, and microsporum gypseum was studied in seawater subjected to different temperature (20--35 degrees c) and salinity (6--50%) levels in diurnal rhythm of 12 h cycles. survival was measured by viability of propagules over a period of 52 weeks. all fungi, except t. cutaneum at 35 degrees c survived the experimental conditions for 52 weeks. temperature was the most influential fac ... | 1979 | 375437 |
| in vitro survival of human pathogenic fungi in hawaiian beach sand. | in vitro studies utilizing 4 pathogenic fungi, trichosporon cutaneum, candida albicans, microsporum gypseum and trichophyton mentagrophytes, all known from hawaiian beaches, indicate that they survive in the fluctuating beach habitat where they can serve as potential sources of infection for significant periods of time. survival was measured by testing the viability of propagules at intervals for 6 months. all species survived 6 months under 1 or more experimental conditions. survival patterns s ... | 1979 | 375438 |
| [in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes]. | in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ... | 1979 | 395583 |
| superficial mycoses in a southern new zealand district. | a total of 2,709 pathogenic fungi were isolated from 8,762 patients suspected as having mycotic disease, over an 8 year period in christchurch, new zealand. the district is climatically designated as temperate with average mean temperatures of 17 degrees c in summer and 8 degrees c in winter. the predominant species of fungi were relatively small in number with trichophyton mentagrophytes var. interdigitals as the major pathogen. fungi other than true dermatophytes, particularly candida spp. and ... | 1979 | 396678 |
| [s-acyl derivatives of thiosalicylamides with antifungal activity. iii]. | some s-acylderivatives of n-monosubstituted amides of thiosalicylic acid in which the n substituents were unsaturated alkyl groups, cyclic or branched saturated alkyl groups, aromatic or aralkyl groups, were prepared and tested for antifungal activity. the substances which were all new were prepared by condensation of 2-mercapto-n-alkylbenzamides with suitable acylating agents. the fungistatic activity of the products was tested in vitro against the following: candida albicans and trichophyton m ... | 1979 | 399922 |
| [synthesis and anti-fungal activity of 5-aminopyrazole derivatives]. | 4-thiocyanato-5-amino or acylaminopyrazoles were prepared and their antifungal activity was tested against candida albicans and trichophyton mentagrophytes: the 4-thiocyanato-5-aminopyrazoles were the most effective in both tests. | 1979 | 399926 |
| [s-acyl derivatives of thiosalicylamides and their anti-fungal activity. iv]. | some s-acyl derivatives of n-alkylthiosalicylamides [table i, ii: substances (i leads to xxxiii)] in which the acyl group on s in a carbamic or thiocarbamic n-monosubstituted group were prepared and tested in vitro for antifungal activity. all the substances which are not previously recorded were prepared by condensation of 2-mercapto-n-alkylbenzamides with suitable isocyanates or isothiocyanates. the fungistatic activity of the products prepared was tested in vitro against the two strains: cand ... | 1979 | 399927 |
| [investigations on the antimicrobial activity of amin-aldehydecondensates. 1. (communication:) symmetrically substituted animals of formaldehyde (author's transl)]. | in the scope of our research about the antimicrobial activity of aldehyde-amin-condenates a number of partly new aminals was synthesized by reaction of formaldehyde with various secondary amines. structures and physically constants are shown in the tables 1 and 2. the antimicrobial activity is demonstrated by the results of the disk-test (table 3), of the minimal inhibition concentration (mic, talbe 4) and the suspension and area disinfecting test following the method of the dghm (tables 5 and 6 ... | 1977 | 410200 |
| [investigations on the antimicrobial activity of amin-aldehyde-condensates. 2. communication: unsymmetrically substituted animals of formaldehyde (author's transl)]. | in the scope of our research about the antimicrobial activity of aldehyde-amin-condensates a number of partly new unsymmetrically substituted animals was synthesized by reaction of formaldehyde with different secondary amines. structures and physically constants are shown in the tables 1 and 2. the antimicrobial activity is demonstrated by the results of the disktest (table 3), of the minimal inhibition concentration (mic, table 4) and the suspension and area disinfecting tests following the met ... | 1977 | 416627 |
| survival and resistance of trichophyton mentagrophytes arthrospores. | the effects of several physical and chemical agents on the survival of trichophyton mentagrophytes arthrospores were investigated. although arthrospores of this dermatophyte were highly resistant to chilling and freezing, they were extremely susceptible to moderate heat (above 50 degrees c) and desiccation. this high susceptibility could be significantly reduced when they were dried in the presence of exogenous proteins. these arthrospores were markedly susceptible to glutaraldehyde. they appear ... | 1978 | 416749 |
| [dermatophytosis, pseudo-dermatophytosis and healthy cutaneous portage observed in platyrhini and cynomorpha monkeys (author's transl)]. | the most frequent tinea of the subhuman primates are microsporosis due to microsporum canis or trichophytosis at trichophyton mentagrophytes and t. simii. the t. mentagrophytes, an anthropo-zoophilic species must be differenciated from t. rubrum and t. interdigitale, dermatophytes of the man; due to the importance of that diagnosis in primate mycology, some tests are used for the differenciation. between the 226 monkeys investigated it was registered: 2 trichophytosis at t. mentagrophytes (an on ... | 1977 | 418728 |
| interactions of trichophyton mentagrophytes and micrococci on skin culture. | scanning electron microscopy was used to search for local or limited synthesis of antibiotics by a strain of trichophyton mentagrophytes. micrococcus luteus, which was susceptible to penicillin and to the dermatophyte when both were cultured on agar media, displayed morphological alterations of flattened walls, invagination, enlargement, and collapse in skin cultures with the fungus. penicillinase did not neutralize these effects. a control strain of staphylococcus spp with poor sensitivity to p ... | 1979 | 422876 |
| comparison of in vitro activity of undecylenic acid and tolnaftate against athlete's foot fungi. | undecylenic acid and tolnaftate were tested in an in vitro test system to evaluate their relative "killing time" efficacy against trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum. commercial products containing these active agents were tested similarly. the pure active agents were equivalent in activity. the commercial product containing undecylenic acid appeared to be more effective against the test organisms than did the product containing tolnaftate. | 1979 | 423138 |
| coumarin-induced disturbances of morphological development and cell wall formation in trichophyton mentagrophytes. | when trichophyton mentagrophytes thalli are placed on a medium containing 300 microgram/ml of coumarin, their growth rate is drastically reduced and the newly formed mycelium consists of curled and branched hyphae showing subapical bulges and swollen tips. under the electron microscope, the most relevant abnormalities concern the cell walls which are often thickened by aberrantly shaped zones that are usually smeared unevenly over the surface of the "primary" wall instead of being deposited in d ... | 1979 | 428619 |
| dermatophytosis caused by trichophyton mentagrophytes in squirrels. | | 1979 | 439541 |
| isolation and partial characterization of immunologically reactive fractions from chitinase digested cell wall of trichophyton mentagrophytes. | cell wall preparations of trichophyton mentagrophytes were digested with chitinase following which various fractions were isolated by ultrafiltration and sephadex gel filtration. all fractions isolated contained both polysaccharide and peptide material. a correlation was seen between those fractions capable of eliciting immediate and delayed skin reactions in sensitized guinea pigs and those capable of stimulating the in vitro proliferation of lymphocytes taken from sensitized guinea pigs. these ... | 1979 | 440399 |
| scytalidium hyalinum infection of skin and nails. | five cases of skin and nail infection associated with scytalidium hyalinum are described. the lesions were confined to the hands, feet and toenails. all the patients were from the west indies and were of negroid descent. scytalidium hyalinum was the only fungus isolated on repeated culture from three patients, while the remaining two patients had mixed infections, one with trichophyton mentagrophytes var. interdigitale and the other with hendersonula toruloidea. | 1979 | 444431 |
| the effects of temperature, incubation atmosphere, and medium composition on arthrospore formation in the fungus trichophyton mentagrophytes. | several growth conditions were found to allow abundant arthrospore formation in t. mentagrophytes. these included growth at 32--37 degrees c on sabouraud's medium (1% neopeptone, 4% glucose) and growth at temperatures below 32 degrees c solely on neopeptone or other complex peptide sources without the addition of glucose, a supplementary carbon source. sabouraud's medium did not allow arthropsore formation at 30 degrees c under normal atmospheric conditions. however, if oxygen tension were reduc ... | 1979 | 455151 |
| differentiation of trichophyton mentagrophytes arthrospores controlled by physical factors. | | 1979 | 470976 |
| dermatophyte species, microscopic and cultural examination. | the dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes var. interdigitale, t. rubrum, and t. verrucosum were compared with respect to the direct microscopic examination of a clinical material and the number of colonies obtained by culture. it was found that the results of microscopy as well as of culture depended to a marked extent upon which species were the cause of the mycosis. the extremes were e. floccosum and t. mentagrophytes var. interdigitale which sh ... | 1979 | 481562 |
| [research of keratinophiles in the soil and their effects on human cutaneous pathology in the lyons area]. | between 1967 and 1977, the systematic research of keratinophiles of the ground in a radius of 30--50 km around lyon, has shown the ubiquitarian predominance of microsporum nanum, which is probably the most ancient occupant of the ground. the most intensive areas of human and animal occupation in the rhodanian tract show the predominance of microsporum gypseum, which is scarcely found in man. sporadic localizations, tightly limites, bound to cirulcation axes and international gathering, let us de ... | 1979 | 488487 |
| effects of different temperatures on cell wall formation and polysaccharide arrangement in trichophyton mentagrophytes: considerations from a cytochemical study. | | 1979 | 490762 |
| [possible predicting of the level of morbidity in the population from trichophytosis caused by trichophyton mentagrophytes var. gypseum]. | | 1979 | 494740 |
| effect of storage temperature on viability of trichophyton mentagrophytes in infected guinea pig skin scales. | the effect of storage temperature on the viability of trichophyton mentagrophytes in infected guinea pig skin scales was quantitatively evaluated for 182 days. infected skin scales were stored, while protected from light, in glass containers with desiccant at four temperatures and sampled after saline treatment at various time intervals. no decrease in viability was observed for storage at 4 degrees c, room temperature, or 30 degrees c. storage at 37 degrees c resulted in a significant loss in v ... | 1979 | 521482 |
| gunacin, a new quinone antibiotic from ustilago sp. | in a screening program for antibiotics which were antagonized by cysteine, a strain, which was characterized as ustilago sp., was found to produce a new quinone antibiotic, gunacin. the molecular weight m+ = 348.084 determined by mass spectroscopy, corresponds to a molecular formula of c17h16o8. further spectroscopic data prove that gunacin is a new antibiotic. the antibiotic possesses a good inhibitory effect against mycoplasmas and gram-positive bacteria including multi-resistant strains. it a ... | 1979 | 528380 |
| growth of trichophyton mentagrophytes on individual amino acids. | trichophyton mentagrophytes was tested for its ability to utilize individual amino acids as a source of carbon and nitrogen in basal medium containing 0.4 mm magnesium sulphate (0.1 g/l) in 0.05 m potassium phosphate buffer at ph6.5. growth was quantitated by measurement of both dry weight and fungal protein. seventeen naturally occurring amino acids supported growth, serving as a source of both carbon and nitrogen. seven amino acids failed to support growth under these conditions; however three ... | 1979 | 531720 |
| filamentous fungal growth assay: correlation between [u-14c] glucose uptake and dry weight determinations. | the filamentous fungus trichophyton mentagrophytes was grown in [u-14c] glucose supplemented nutrient broth. growth was monitored in 200 microliter microcultures and 5 ml macrocultures by measuring the incorporation of 14c into trichloroacetic acid-insoluble macromolecules and in macrocultures by dry weight determination. adjustment of the specific activity of the [u-14c] glucose medium supplement from 1080 muci/mmole to 108 muci/mmole decreased the rate of isotope uptake and prolonged availabil ... | 1979 | 531722 |
| suppression of in vitro lymphocyte transformation during an experimental dermatophyte infection. | during primary trichophyton mentagrophytes infection of strain 2 guinea pigs, the colony-forming units (cfu) of fungi present within the lesion peaked between days 7 and 14, whereas the severity of the lesion itself peaked between days 11 and 16. concomitant with the latter peak, a pronounced depression in the in vitro mitogenic activity of spleen cells (spc) and lymph node cells (lnc) was observed. only after resolution of the primary infection (day 21) did lnc show increased deoxyribonucleic a ... | 1979 | 546787 |
| [preparation and antifungal activity of carbamic and thiocarbamic esters of thiophenols]. | a series of n-substituted carbamic and thiocarbamic esters of thiophenols [substances (i leads to xlii)] was prepared and tested for in vitro antifungal activity. the substances were obtained by condensation of thiophenols with suitable isocyanates and isothiocyanates. the antifungal activity of the products was tested in vitro against the following strains: candida albicans, candida tropicalis, saccharomyces cerevisiae and trichophyton mentagrophytes. the results obtained, given in the table i, ... | 1979 | 554798 |
| architecture and chemistry of microconidial walls of trichophyton mentagrophytes. | the ultrastructure and chemical composition of the walls of trichophyton mentagrophytes microconidia were investigated with particular emphasis on the localization of the major structural components within the walls. the walls consisted of carbohydrate (56.1% neutral polysaccharide, and 16.0% chitin), protein (22.6%), lipid (6.5%), ash (1.7%), and trace amounts of melanin (0.2%) and phosphorus (0.2%). in thin sections, three distince layers were recognized. the electron-transparent pellicle (15 ... | 1977 | 557473 |
| [microsporum persicolor, an easily misinterpreted dermatophyt]. | trichophyton persicolor was described by sabouraud in 1910, and was mistaken by most mycologists for trichophyton mentagrophytes. recently the infection in wild rodents was discovered and the independence of this fungus proved by its perfect form (nannizzia persicolor) which is called at the present time microsporum persicolor. | 1978 | 564336 |
| dermatophytosis survey in lagos state of nigeria. | a dermaphytosis survey covering 3,860 schoolchildren was conducted in lagos, nigeria, between january 1973 and january 1974. seven species of dermatophytes, namely, trichophyton mentagrophytes (four isolates), t. rubrum (three isolates), t. soundanense (11 isolates), microsporum canis (five isolates), m. gypseum (two isolates), m audouinii (four isolates), and epidermophyton floccosum (three isolates) were recovered from specimens collected from the hair, skin and scalp scrapings of 81 schoolchi ... | 1977 | 595081 |
| plasmalemmasome development in trichophyton mentagrophytes grown at suboptimal temperature. | when the dermatophytic fungus trichophyton mentagrophytes is cultivated at the suboptimal temperature of 19 degrees c, the plasmalemma of the youngest cells appears to be associated with a variety of membranous bodies, the number of which is much greater than at the optimum temperature of 28 degrees c. these structures can be indicated as plasmalemmasomes both for morphological characteristics and cytochemical reactivity. a possible correlation between the suboptimal condition and plasmalemmasom ... | 1977 | 608349 |
| resistance of selected saprobic and zoopathogenic fungi to cycloheximide. | spore germination was used as an assay to measure the sensitivities of selected fungi (achlya bisexualis, cladosporium sp., trichophyton mentagrophytes and microsporum gypseum) to cyclohexamide and to determine their abilities to adapt to the drug. two patterns of response were noted. the saprobes, a. bisexualis and cladosporium sp., demonstrated acquired resistance. spores from hyphae previously exposed to cycloheximide either germinated in the presence of concentrations of the drug that comple ... | 1978 | 632807 |
| isolation of glycopeptides with skin test activity from dermatophytes. | by using ethylene glycol extraction of whole submerged cultures followed by sephadex g-200 and diethylaminoethyl-sephadex chromatography, we isolated four distinct glycopeptides from trichophyton mentagrophytes, t. rubrum, and microsporum canis. chemical analyses revealed that these glycopeptides contained mostly carbohydrate (42.5 to 81.6%) and protein (4.3 to 11.3%), with lesser amounts of phosphorus (0.4 to 6.0%) and hexosamines (0.3 to 0.6%). based upon total carbohydrate and monosaccharide ... | 1978 | 640721 |
| antifungal properties of halofumarate esters. | alkyl esters (c1--c4) of the four halofumaric acids were tested for antifungal activity against candida albicans, aspergillus niger, mucor mucedo, and trichophyton mentagrophytes at ph 5.6 and 7.0 in the absence and presence of 10% beef serum in sabouraud dextrose agar. the most toxic compound to each organism was: c. albicans, ethyl iodofumarate (0.054 mmole/liter); a. niger, methyl bromofumarate (0.090 mmole/liter); m. mucedo, methyl fluorofumarate (0.037 mmole/liter); and t. mentagrophytes, e ... | 1978 | 641780 |
| experimental trichophyton mentagrophytes infection in hairless and haired dogs. | | 1978 | 642447 |
| [fungus infection in a guinea pig as a cause of human infection (author's transl)]. | a case of fungus infection in a guinea pig is reported which was found to have caused human dermatomycosis resulting from trichophyton mentagrophytes infection. a number of diagnostic features are discussed. | 1978 | 653698 |
| visual micromethod for assay of fungal growth. | a visual micromethod for measuring antifungal effects on germination and growth is described. the antifungal agent griseofulvin and the fungus trichophyton mentagrophytes were used as materials to compare the micromethod with a standard assay based on dry mycelial weight. the micromethod was more sensitive than the weight method in detecting the minimum inhibitory concentration of griseofulvin (0.18 and 35 microgram/ml, respectively). at higher concentrations of griseofulvin (22.5 microgram/ml), ... | 1978 | 657010 |
| in vitro and in vivo studies of ambruticin (w7783): new class of antifungal antibiotics. | ambruticin is a cyclopropyl-pyran acid, representing a new class of antibiotics. it has a relatively broad antifungal spectrum in vitro and is highly active against dimorphic as well as filamentous organisms. of 24 strains of dermatophytic fungi tested, the majority were susceptible to ambruticin at 0.049 mug/ml or less. the minimal inhibitory concentration for the systemic fungi histoplasma capsulatum and blastomyces dermatitidis was 0.049 to 0.39 mug/ml. ambruticin is fungicidal for metabolizi ... | 1978 | 666301 |
| in vitro and in vivo photosensitized inactivation of dermatophyte fungi by heterotricyclic dyes. | the ability of three heterotricyclic dyes to photosensitize dermatophyte fungi was studied with trichophyton mentagrophytes and microsporum gypseum. in vitro studies showed that methylene blue, neutral red, and proflavine were capable of killing these fungi when used in conjunction with broad-spectrum light. proflavine, however, killed both fungi most rapidly and was used for further studies. fungal killing by proflavine plus light was dependent on dye concentration, ph, light wavelength, and li ... | 1978 | 669788 |
| [the occurrence of non-volatile organic acids in cultures of trichophyton mentagrophytes (robin) blanchard. 9. chemical and physiological--chemical studies on dermatophytes, also 31. chemistry and physiology of metabolic chemically important acids]. | | 1978 | 674281 |
| [value and method of the urease test in the differentiation of trichophyton rubrum and trichophyton mentagrophytes]. | | 1978 | 680296 |
| semisynthetic cephalosporins with antifungal activity: laboratory studies on 2-pyridinethiol 1-oxide cephalosporins. | cephalosporins are chemotherapeutic agents whose spectrum and use are limited to antibacterial activity. therefore, it was of interest to find several new semisynthetic cephalosporins which possess in vitro antifungal activity against trichophyton mentagrophytes, candida albicans and certain other yeasts. five new cephalosporins containing the 2-pyridinethiol 1-oxide grouping were examined. four with this heterocyclic moiety in the 3-position were found to have activity. one with the grouping in ... | 1978 | 681239 |
| effect of leaf extracts of aloe arborescens mill subsp. natalensis berger on growth of trichophyton mentagrophytes. | the antifungal activity of a lyophilized powder containing aloe leaf homogenate (whole-leaf powder) against trichophyton mentagrophytes was investigated. the minimal inhibitory concentration was 25 mg/ml by the agar dilution method, using sabouraud glucose agar medium. at subinhibitory concentrations, the powder exerted its main effect on colony growth by prolongation of the lag phase and inhibition of growth rate. homogenates of fresh whole leaf were filtered through whatman gf/a paper, and the ... | 1978 | 686703 |
| scanning electron microscopy of experimental trichophyton mentagrophytes infections in guinea pig skin. | trichophyton mentagrophytes invasion of guinea pig skin was examined by scanning electron microscopy. biopsies were obtained daily for 12 days from experimental infection sites. dermatophyte invasion, examined in detail by scanning electron microscopy of cross-sectioned, prefixed skin was evidenced by: the appearance of hyphae within the stratum corneum; follicular invasion by hyphae, which remained initially within the follicle wall; emergence of the hyphae from the wall into the follicular can ... | 1978 | 711318 |
| effect of occlusion on trichophyton mentagrophytes infections in guinea pigs. | the effect of occlusion and griseofulvin on the duration and severity of acute dermatophytosis was assessed in guinea pigs. sixty guinea pigs given standard trichophyton mentagrophytes infections were divided into 5 groups: (a) control, (b) intermittent wet occlusion, (c) continuous-wet occlusion, (d) griseofulvin, (e) griseofulvin-continuous-wet occlusion. lesions were largest in the control group, smallest in the griseofulvin-continuous-occlusion group, and of intermediate area in the other gr ... | 1978 | 712105 |
| synthesis and evaluation of 1-(hydroxyphenyl)-1-nonen-3-ones and related compounds for antineoplastic and antimicrobial activities. | some 1-(hydroxyphenyl)-1-nonen-3-ones, the corresponding mannich bases, and o-benzoyl esters were synthesized. evaluation of these derivatives against murine p-388 lymphocytic leukemia indicated that, while the hydroxyphenyl styryl ketones and related esters were devoid of significant anticancer activities, etherification of the nuclear hydroxyl group gave compounds with a discernible increase in mean survival time. the hydroxyphenyl styryl ketones showed marked potencies against two pathogenic ... | 1978 | 712589 |
| carotenogenesis associated with arthrosporulation of trichophyton mentagrophytes. | carotenoid pigments were demonstrated in arthrospores of the dermatophyte trichophyton mentagrophytes but were absent from hyphae and microconidia of this fungus. incubation at higher temperatures (39 degrees c) allowed arthrosporulation to occur, but essentially no carotenoid was detected in such arthrospores. the carotenoid formation in arthrosporulating t. mentagrophytes did not appear to be either induced or stimulated by light illumination. mature arthrospores contained the carotenoids phyt ... | 1978 | 721775 |
| [investigations on the antimicrobial activity of amin-aldehyde-condensates. 5. communication: azomethins of benzaldehyde (author's transl)]. | in the scope of our research about the antimicrobial activity of amin-aldehyde-condensates a number of benzylidene-amines (azomethins of benzyldehyde) was synthesized by condensation of primary amines with benzaldehyde. structures and physical constants are shown in table 1 and 2. the antimicrobial activity of these benzylidene-amines is demonstrated by the results of the disk-test (table 3), of the minimal inhibition concentration test (mic, table 4) and the suspension test (table 5) following ... | 1978 | 735566 |
| comparative in vitro & in vivo evaluation of tolciclate, tolnaftate, miconazole, clotrimazole & undecylenic acid against trichophyton mentagrophytes. | | 1978 | 750408 |
| experimental inoculation of dermatophytes on psoriatic skin. | two dermatophytic agents, trichophyton rubrum and trichophyton mentagrophytes were used in the experimental inoculation of psoriatic lesions in 27 volunteer patients (13 males and 14 females with an age range from 17 to 72 yr). t. rubrum was inoculated in 14 patients and t. mentagrophytes (varietas granulare) in 13. for purposes of control in each patient the same agent was also inoculated on healthy skin. results were noted once a week for a period of 1 mo. a positive response was found in 12 o ... | 1979 | 762446 |
| on the fungitoxicity of some new thiocyanatopyrazole derivatives: electron microscopical study in trichophyton mentagrophytes. | four thiocyanatopyrazole derivatives were synthesized and their fungistatic activity was demonstrated in vitro against a number of dermatophytic fungi. in trichophyton mentagrophytes, the most active compound induced as unusual increase of the plasma membrane with production of intra and extracytoplasmic complexes, a deterioration of nuclear and mitochondrial membranes and a formation of autophagic-like vacuoles. plasmolysis, accompanied by an almost complete disorganization of cytoplasmic struc ... | 1976 | 778623 |
| antifungal activity of 4-substituted crotonic acid esters. | twenty-three 4-substituted crotonic acid esters were tested for antifungal activity against candida albicans, aspergillus niger, mucor mucedo, and trichophyton mentagrophytes. for the analogues of the methyl ester containing substituents in the 4 position, the following order of fungitoxicity was observed: i greater than br greater than cl greater than ch3s greater than ch3o greater than f=h. of the homologues of the esters of the 4-iodo and 4-bromo compounds which included methyl, ethyl, n-prop ... | 1976 | 787525 |
| lymphocyte transformation in vitro in dermatophytosis. | peripheral blood lymphocytes from 59 patients with dermatophytosis and from nine young healthy women were studied by the lymphocyte transformation test (lt) using mitogens and bacterial as well as fungal antigens. the latter included candida albicans (ca) and four dermatophyte species, viz. trichophyton rubrum (tr), trichophyton mentagrophytes (tm), epidermophyton floccosum (ef) and microsporum canis (mf). most of the patients showed normal transformation in response to mitogens and non-dermatop ... | 1976 | 793301 |
| synthesis and antimicrobial evaluation of substituted 5,6-dihydro-5-nitrouracils. | reaction of 5-nitrouracil derivatives with sodium borohydride in methanol-water, followed by neutralization of the product with acid, has produced 5,6-dihydro-5-nitrouracil (5) 5,6-dihydro-6-dihydro-6-methyl-5-nitrouracil (7), 5,6-dihydro-5-nitro-1-(4-nitrophenyl)uracil (10), and 5,6-dihydro-5-nitro-1(beta-d-ribofuranuronic acid ethyl ester)uracil (12). in assays for antimicrobial activity using strains of escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, candida albicans, and tri ... | 1976 | 823335 |
| dermatophyte isolation media: quantitative appraisal using skin scales infected with trichophyton mentagrophytes and trichophyton rubrum. | various dermatophyte isolation media were quantitatively appraised by colony counts for their ability to support growth when suspensions of trypsin-treated infected-skin scales were used as inocula. evaluation included guinea pig skin scales infected with a granular trichophyton mentagrophyton mentagrophytes, and one trial was conducted using human skin scales infected with trichophyton rubrum. no differences in the ability to support growth were observed among taplin dermatophyte test medium, d ... | 1977 | 833268 |
| evaluation of the in vitro antifungal activity of allicin. | allicin was effective in vitro against candida, cryptococcus, trichophyton, epidermophyton, and microsporum. the minimal inhibitory concentrations (mics) of allicin against these organisms were 3.13 to 6.25 mug/ml by the agar dilution method and 1.57 to 6.25 mug/ml by the broth dilution method, using sabouraud glucose (sg) medium. however decreased activity was demonstrated against aspergillus. the mic of allicin against various pathogenic fungi was affected considerably by differences in the ex ... | 1977 | 856026 |
| temporal correlation of lymphocyte blastogenesis, skin test responses and erythema during dermatophyte infections. | the development of cellular hypersensitivity, as measured by lymphocyte blastogenic and skin tests assays, was correlated with intensification of lesion erythema in guinea-pigs infected with trichophyton mentagrophytes. development of lymphocyte blastogenic responses to trichophytin was assayed using forty infected animals and twenty controls; blastogenic conversion occurred between 9-11 days post spore application. the onset of cellular hypersensitivity was assayed in vivo in twenty infected gu ... | 1977 | 862239 |
| [effect of 8-methoxypsoralen and blacklight on microorganisms in vitro and in experimental trichophytosis in guinea pigs]. | the lack of experimental test models causes problems in comparative evaluation of photodynamic effects of 8-mop and its possible derivatives after irradiation with blacklight or other irradiation sources. in our experiments in vitro, tests with various microorganisms and the in vivo model of experimental dermatophytosis in guinea pigs by trichophyton mentagrophytes appeared to be suitable. in vivo, 8-mop was applicated orally and topically in two formulations. | 1977 | 863062 |
| development of arthrospores of trichophyton mentagrophytes. | arthrosporogenesis of the dermatophyte trichophyton mentagrophytes was examined by light and by scanning and transmission electron microscopy. sabouraud dextrose agar plates were inoculated with microconidia and incubated in an atmosphere of 8% co2. typical germination and hyphal branching continued to day 4, when hyphae began to be increasingly coated with granular-fibrillar material. multiple replication of nuclei and formation of segregating septa followed. by day 6 the thick surface mesh som ... | 1977 | 870436 |
| external hordeolum (sty) caused by infection with trichophyton mentagrophytes. | | 1977 | 873673 |
| submicroscopic morphology of trichophyton mentagrophytes grown at different temperatures. | several modifications were observed in trichophyton mentagrophytes cultivated at 19 degrees and 37 degrees c, i.e. nine degrees below and above the optimum of 28 degrees c. the phenomena included inhibition of the growth rate, changes in the gross aspects of the cultures as well as of the microscopic and submicroscopic morphology of the hyphal cells. at the ultrastructural level, in particular, it was shown that, at the suboptimal temperature, although the organelle structure in both young and a ... | 1977 | 895831 |
| [trichophyton mentagrophytes v. quinckeanum in man]. | | 1977 | 897231 |
| [epidemiology of trichophytosis caused by trichophyton mentagrophytes var. gypseum]. | | 1977 | 899224 |
| topically applied antifungal agents. percutaneous penetration and prophylactic activity against trichophyton mentagrophytes infection. | penetration and prophylactic activity against trichophyton mentagrophytes infection of topically applied antifungal agents were studied in human volunteers. the concentration and persistence of drug in the stratum corneum was determined after different treatment schedules and from different vehicles. measurable levels of griseofulvin, clotrimazole, miconazole nitrate, and thiabendazole remained in the skin four days after discontinuation of topical applications. griseofulvin, miconazole, and clo ... | 1977 | 931391 |
| the effect of temperature and humidity on the growth of trichophyton mentagrophytes spores on human stratum corneum in vitro. | | 1976 | 939042 |
| isolation and characterization of the rodlet layer of trichophyton mentagrophytes microconidial wall. | the rodlet layer of the microconidial wall of trichophyton mentagrophytes was isolated and partially characterized. the purified microconidial walls were first extracted with urea (8m), mercaptoethanol (1%), and sodium dodecyl sulfate (1%) followed by enzymatic digestion with glusulase (snail intestinal enzymes) and purified (1 leads to 3)-beta-d-glucanase and chitinase. the purified rodlet layer was 15 to 30 nm thick and accounted for approximately 10% of the original wall weight. the pattern o ... | 1976 | 956129 |
| studies on the biological effects of deuteriated organic compounds. i. antifungal activity of perdeuteriated fatty acids on dermatophytes in vitro. | the antifugal activity of some perdeuteriated fatty acids, with normal chain 11 to 18 carbon atoms, was investigated on common dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes and t. rubrum under in vitro conditions. these studies were performed by dilution technique and with respiratory measurements, perdeuteriation of some fatty acids increases their inhibitory effect on the dermatophyte growth. perdeuteriated n-hendecanoic acid proved to be the most activ ... | 1976 | 967223 |
| peptido polysaccharide antigens from trichophyton mentagrophytes var. granulosum. | two highly purified peptido polysaccharide antigens have been isolated from surface-grown cultures of trichophyton mentagrophytes var. granulosum. trichloroacetic acid extraction and ethanol precipitation yielded a mixture containing high-molecular-weight components which were first separated on sephadex g-200. subsequent fractionation by ion-exchange chromatography on de-52-cellulose (borate form) yielded the two peptido polysaccharides. both of the peptido polysaccharides reacted with rabbit a ... | 1976 | 971953 |
| synthesis and preliminary antimicrobial screening of two thiosulfonates. | tetramethylene bis(methanethiosulfonate), the s-ester analog of busulfan, was prepared by reacting 1,4-dibromobutane with potassium methanethiosulfonate. 2,4-dichlorophenyl methanethiosulfonate was prepared by reacting sodium methanesulfinate with 2,4-dichlorobenzenesulfenyl chloride. neither compound showed antifungal activity against microsporum audouini or trichophyton mentagrophytes. although tetramethylene bis(methanethiosulfonate) was more active against staphylococcus aureus than was 2,4- ... | 1976 | 994004 |
| trichophyton mentagrophytes infection in laboratory white mice. | trichophyton mentagrophytes infection was studied in a breeding colony of 42 white mice. symptoms were observed in only 3 out of the 12 animals shown to carry dermatophyte on their coats. literature on trichophyton mentagrophytes infection mice is reviewed. the use of the technique developed by mariat & tapia (16) to isolate dermatophytes on cultures, specially for epidemiological surveys, is postulated. attention is called to the importance of healthy animals, directly or indirectly, as carrier ... | 1976 | 995167 |