| progress towards butyrate-producing pharmabiotics: butyricicoccus pullicaecorum capsule and efficacy in tnbs models in comparison with therapeutics. | | 2014 | 23766442 |
| in vitro characterization of gastrointestinal behavior of butyricicoccus pullicaecorum, a novel butyrate producing isolate with probiotic potential to counterbalance dysbiosis in inflammatory bowel disease. | | 2013 | 23875313 |
| safety assessment of the butyrate-producing butyricicoccus pullicaecorum strain 25-3(t), a potential probiotic for patients with inflammatory bowel disease, based on oral toxicity tests and whole genome sequencing. | inflammatory bowel disease (ibd) is a chronic inflammation of the digestive tract, characterized by dysbiosis of the intestinal microbiota. probiotics have been suggested as a strategy to reduce active disease or extend remission. we isolated and characterized the butyrate-producing strain butyricicoccus pullicaecorum 25-3(t) and identified it as a potential probiotic for patients with ibd. to evaluate the safety of 25-3(t) for use in humans, we conducted a standard acute oral toxicity test and ... | 2014 | 25007784 |
| butyricicoccus pullicaecorum, a butyrate producer with probiotic potential, is intrinsically tolerant to stomach and small intestine conditions. | butyrate has several beneficial properties that are essential to maintain gastrointestinal health. therefore butyrate-producing bacteria are seen as the next generation of probiotics. the butyrate-producing bacterium butyricicoccus pullicaecorum (a clostridial cluster iv strain) is such a promising probiotic candidate for people suffering from inflammatory bowel disease. to exert its beneficial properties, it is crucial that b. pullicaecorum survives the harsh conditions of the upper gastrointes ... | 2014 | 25179909 |
| interindividual differences in response to treatment with butyrate-producing butyricicoccus pullicaecorum 25-3t studied in an in vitro gut model. | butyrate-producing bacteria are promising probiotic candidates to target microbial dysbiosis in gastrointestinal disorders like inflammatory bowel diseases. butyricicoccus pullicaecorum 25-3(t), a butyrate-producing clostridial cluster iv strain, is such a candidate. little is known about its abundance in the colon microbiota and its butyrogenic properties. we used the m-shime(®), an in vitro simulator for the human intestinal microbial ecosystem, to study the effect of supplementing a single do ... | 2015 | 25999470 |
| hydrodynamic chronoamperometry for probing kinetics of anaerobic microbial metabolism--case study of faecalibacterium prausnitzii. | monitoring in vitro the metabolic activity of microorganisms aids bioprocesses and enables better understanding of microbial metabolism. redox mediators can be used for this purpose via different electrochemical techniques that are either complex or only provide non-continuous data. hydrodynamic chronoamperometry using a rotating disc electrode (rde) can alleviate these issues but was seldom used and is poorly characterized. the kinetics of faecalibacterium prausnitzii a2-165, a beneficial gut m ... | 2015 | 26127013 |
| capturing one of the human gut microbiome's most wanted: reconstructing the genome of a novel butyrate-producing, clostridial scavenger from metagenomic sequence data. | the role of the microbiome in health and disease is attracting great attention, yet we still know little about some of the most prevalent microorganisms inside our bodies. several years ago, human microbiome project (hmp) researchers generated a list of "most wanted" taxa: bacteria both prevalent among healthy volunteers and distantly related to any sequenced organisms. unfortunately, the challenge of assembling high-quality genomes from a tangle of metagenomic reads has slowed progress in learn ... | 2016 | 27303377 |
| agathobaculum butyriciproducens gen. nov. sp. nov., a strict anaerobic, butyrate-producing gut bacterium isolated from human faeces and reclassification of eubacterium desmolans as agathobaculum desmolans comb. nov. | a novel bacterial strain, sr79t, was isolated from a korean faecal sample and characterized using a polyphasic approach. sr79t was found to be a strictly anaerobic, gram-stain-positive, non-spore-forming, non-motile, catalase- and oxidase-negative short rod with no flagella. sr79t grew optimally at 37 °c in the presence of 0.5 % (w/v) nacl at ph 7. the nacl range for growth was 0-1 % (w/v). the isolate produced butyric acid (>18 mm) as a major end product. a phylogenetic analysis based on 16s r ... | 2016 | 27334534 |
| reclassification of eubacterium desmolans as butyricicoccus desmolans comb. nov., and description of butyricicoccus faecihominis sp. nov., a butyrate-producing bacterium from human faeces. | a gram-positive-staining, coccoid-shaped, non-motile, asporogenous, obligately anaerobic and butyrate-producing bacterium was recovered from a healthy human's faeces. the organism was isolated by the enrichment culture technique using yeast extract-casein hydrolysate-fatty acids broth supplemented with 0.5 % mucin. phylogenetic analysis of 16s rrna gene sequences demonstrated that the novel strain should be classified as a member of the eubacterium desmolans-related cluster in the family ruminoc ... | 2016 | 27453394 |
| the probiotic butyricicoccus pullicaecorum reduces feed conversion and protects from potentially harmful intestinal microorganisms and necrotic enteritis in broilers. | probiotics which do not result in the development and spread of microbial resistance are among the candidate replacements for antibiotics previously used as growth promotors. in this study the effect of in-feed supplementation of the butyrate producing butyricicoccus pullicaecorum strain 25-3(t) on performance, intestinal microbiota and prevention of necrotic enteritis (ne), a disease caused by clostridium perfringens was evaluated in broilers. for the performance study, day old ross 308 chicks ... | 2016 | 27708624 |
| butyricicoccus pullicaecorum in inflammatory bowel disease. | objective: many species within the phylum firmicutes are thought to exert anti-inflammatory effects. we quantified bacteria belonging to the genus butyricicoccus in stools of patients with ulcerative colitis (uc) and crohn's disease (cd). we evaluated the effect of butyricicoccus pullicaecorum in a rat colitis model and analysed the ability to prevent cytokine-induced increases in epithelial permeability. design: a genus-specific quantitative pcr was used for quantification of butyricicoccus in ... | 2012 | 23263527 |
| butyricicoccus pullicaecorum gen. nov., sp. nov., an anaerobic, butyrate-producing bacterium isolated from the caecal content of a broiler chicken. | five isolates that produced large amounts of butyrate were obtained in the course of a study on the butyrate-producing microbiota from the caecal content of a 4-week-old broiler chicken. the five isolates were virtually indistinguishable in biochemical and genetic terms, suggesting that they were derived from a single bacterial clone colonizing this habitat. a phylogenetic analysis based on 16s rrna gene sequences demonstrated that the five isolates represented a unique lineage within the clostr ... | 2008 | 19060061 |