| lambertellols a and b, novel 3,4-dihydronaphthalen-1(2h)-ones with spiro-butenolide produced by lambertella sp.1346. | [structure: see text] lambertella sp. 1346 was found to produce lambertellols a (1) and b (2) carrying a novel dihydronaphthalen-1(2h)-ones with spiro-1-furan-2(5'h)-one. the spiro-lactone ring moiety of both 1 and 2 were easily migrated to afford lambertellin, a known metabolite of lambertella corni-maris. the absolute stereochemistry of these compounds was established on the basis of cd spectrum after chemical derivatization. | 2004 | 14723517 |
| stimulation of the biosynthesis of the antibiotics lambertellols by the mycoparasitic fungus lambertella corni-maris under the acidic conditions produced by its host fungus in vitro. | the filamentous fungus, lambertella corni-maris (l. corni-maris), a mycoparasite on monilinia fructigena, produces the antibiotics, lambertellols a (1), b (2), and lambertellin (3), in a substantial amounts under acidic conditions, whereas these antibiotics were hardly detected when the fungus was cultured on a potato-sucrose (ps) medium without added acids. our investigations also revealed that the host, m. fructigena, changed its surroundings into acidic conditions, suggesting that the acidic ... | 2007 | 17485857 |