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fatal cerebral mycoses caused by the ascomycete chaetomium strumarium.three cases of fatal cerebral mycosis in males with prior histories of intravenous drug use from the united states and australia are reported. infection in each case was limited to brain abscess; no other sites of infection were observed. the fungus seen by histopathology and isolated from the brain tissue in each case was identified as chaetomium strumarium. this is the first report of human infection by this species, and c. strumarium is the second species of chaetomium known to cause primary ...19958567907
ultrastructural alterations produced by sertaconazole on several opportunistic pathogenic fungi.sertaconazole is a new synthetic antifungal which has shown promising activity against numerous fungi. the morphological changes induced by the drug at two concentrations, the mic and 10 times the mic, during 24 and 48 h on the filamentous opportunistic fungi aspergillus fumigatus, chaetomium atrobrunneum and scedosporium prolificans indicated that the intensity of the ultrastructural breakdown depended on the dose and not on the time of exposure. common severe alterations of many fungal cells, ...19958683408
cerebral fungal infections in the immunocompromised host: a literature review and a new pathogen--chaetomium atrobrunneum: case report.a case of a cerebral abscess, occurring in a patient who had undergone bone marrow transplant, caused by a new pathogen, chaetomium atrobrunneum, and a review of the literature are presented. although aspergillus species are by far the most common fungi found in cerebral abscesses in immunocompromised patients, an increasing number of fungi commonly found in nature but not usually associated with infections in humans have been isolated from cerebral abscesses in these patients.19989848862
fatal chaetomium cerebritis in a bone marrow transplant patient.the number of opportunistic infections in the central nervous system (cns) has been steadily increasing because of a rising number of immunocompromised patients. a rare form of cns infection can be caused by chaetomium species, one of the largest genera of saprophytic ascomycetes. the cns lesions in the present case were caused by chaetomium atrobrunneum. the main characteristic of almost all chaetomium species is presence of hairs or setae covering the ascomata. microbiological studies are the ...199910414510
cerebral fungal infections in the immunocompromised host: a literature review and a new pathogen--chaetomium atrobrunneum: case report. 199910414589
chaetoatrosin a, a novel chitin synthase ii inhibitor produced by chaetomium atrobrunneum f449.chaetoatrosin a, a novel chitin synthase ii inhibitor, was isolated from the culture broth of fungus f449, which was identified as chaetomium atrobrunneum f449. chaetoatrosin a was purified by solvent partition, silica gel, ods, preparative tlc, and sephadex lh-20 column chromatographies, consecutively. the structure of chaetoatrosin a was assigned as 1,8-dihydroxy-3(2-hydroxypropionyl)-6-methoxynaphthalene on the basis of various spectroscopic analyses including uv, ir, mass spectral, and nmr. ...200010819295
clavispora lusitaniae and chaetomium atrobrunneum as rare agents of cutaneous infection.we describe the first case of cutaneous infection caused by chaetomium atrobrunneum and clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid. he presented to our outpatient center with a 6-day history and previously ineffective antibacterial therapy. scanning electron microscopy (sem) revealed hyphae and spores were on the surface of the crusty exudates and also penetrated into it, and the microbiology study further showed their charact ...201020020214
catalytic properties and classification of cellobiose dehydrogenases from ascomycetes.putative cellobiose dehydrogenase (cdh) genes are frequently discovered in various fungi by genome sequencing projects. the expression of cdh, an extracellular flavocytochrome, is well studied in white rot basidiomycetes and is attributed to extracellular lignocellulose degradation. cdh has also been reported for plant-pathogenic or saprotrophic ascomycetes, but the molecular and catalytic properties of these enzymes are currently less investigated. this study links various ascomycetous cdh gene ...201121216904
fungal keratitis caused by chaetomium atrobrunneum.we report a case of mycotic keratitis caused by a rare fungus chaetomium atrobrunneum.201222045390
chaetomium atrobrunneum and aspergillus fumigatus in multiple tracheal aspirates: copathogens or symbiosis.chaetomium atrobrunneum has never been reported to be associated with pneumonia. we report the isolation of c. atrobrunneum and aspergillus fumigatus from a chinese elderly patient with fatal pneumonia. branched, long, and septate hyphae were observed in potassium hydroxide preparations and gram-stained smears, and confluent c. atrobrunneum growth and a few a. fumigatus colonies were found in tracheal aspirates (nine separate occasions). these isolates were identified by conventional morphologic ...201626880338
expression of two novel β-glucosidases from chaetomium atrobrunneum in trichoderma reesei and characterization of the heterologous protein products.two novel gh3 family thermostable β-glucosidases from the filamentous fungus chaetomium atrobrunneum (cel3a and cel3b) were expressed in trichoderma reesei, purified by two-step ion exchange chromatography, and characterized. both enzymes were active over a wide range of ph as compared to neurospora crassa β-glucosidase gh3-3, which was also expressed in t. reesei and purified. the optimum temperature of both c. atrobrunneum enzymes was around 60 °c at ph 5, and both enzymes had better thermal a ...201627714589
chaetomium retinitis.to report a case of chaetomium atrobrunneum retinitis in a patient with hodgkin lymphoma.201025390107
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