Publications

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echinococcus felidis in hippopotamus, south africa.hydatid cysts of echinococcus felidis are described from the hippopotamus (hippopotamus amphibius) from mpumalanga province, south africa. among six hippopotami investigated, hepatic hydatids were found in three. the identification was based on mitochondrial and nuclear dna sequences. in addition, the rostellar hook morphology was analysed. this is the first morphological description of the metacestode of e. felidis, and the first molecularly confirmed report of the intermediate host of e. felid ...201728807300
a survey for echinococcus spp. of carnivores in six wildlife conservation areas in kenya.to investigate the presence of echinococcus spp. in wild mammals of kenya, 832 faecal samples from wild carnivores (lions, leopards, spotted hyenas, wild dogs and silver-backed jackals) were collected in six different conservation areas of kenya (meru, nairobi, tsavo west and tsavo east national parks, samburu and maasai mara national reserves). taeniid eggs were found in 120 samples (14.4%). in total, 1160 eggs were isolated and further analysed using rflp-pcr of the nad1 gene and sequencing. 3 ...201424732034
the first report of human-derived g10 genotype of echinococcus canadensis in china and possible sources and routes of transmission.cystic echinococcosis (ce) is one of the most important parasitic zoonoses. 10 distinct genotypes, designated g1-g10 genotypes of echinococcus granulosus sensu lato (s.l.), have been split into 4 species: echinococcus granulosus sensu stricto (s.s.) (g1-g3), echinococcus equinus (g4), echinococcus ortleppi (g5) and echinococcus canadensis (g6-g10); echinococcus felidis has also been suggested as a sister taxon of e. granulosus s.s. recently. four genotypes belonging to two species (g1 and g3 gen ...201525967082
taxonomy and molecular epidemiology of echinococcus granulosus sensu lato.echinococcus granulosus, formerly regarded as a single species with a high genotypic and phenotypic diversity, is now recognised as an assemblage of cryptic species, which differ considerably in morphology, development, host specificity (including infectivity/pathogenicity for humans) and other aspects. this diversity is reflected in the mitochondrial and nuclear genomes and has led to the construction of phylogenetic trees and hypotheses on the origin and geographic dispersal of various taxa. b ...201526264250
a novel zoonotic genotype related to echinococcus granulosus sensu stricto from southern ethiopia.complete mitochondrial and two nuclear gene sequences of a novel genotype (gomo) related to echinococcus granulosus sensu stricto are described from a metacestode isolate retrieved from a human patient in southwestern ethiopia. phylogenetically, the genotype is positioned within the e. granulosus sensu stricto/echinococcus felidis cluster, but cannot easily be allocated to either species. based on different mitochondrial dna markers, it is closest to the haplotype cluster that currently defines ...201627181929
a novel pcr-rflp assay for molecular characterization of echinococcus granulosus sensu lato and closely related species in developing countries.cystic echinococcosis, due to echinococcus granulosus sensu lato (s. l.), currently affects three million people, especially in low-income countries and results in high livestock production loss. dna-based methods demonstrated genetic variability of e. granulosus s. l., and five species were recognized to belong to the complex, including e. granulosus sensu stricto (s.s) (genotypes g1-g3), echinococcus equinus (genotype g4), echinococcus ortleppi (genotype g5), echinococcus canadensis (genotypes ...201627225001
cystic echinococcosis: future perspectives of molecular epidemiology.human cystic echinococcosis (ce) has been considered to be caused predominantly by echinococcus granulosus sensu stricto (the dog-sheep strain). molecular approaches on ce, however, have revealed that human cases are also commonly caused by another species, echinococcus canadensis. all indices for classification and standardization of ce pathology including available images, epidemiology, diagnostics and treatment are currently based largely on a mixture of infections which include at least e. g ...201727237060
a survey of echinococcus species in wild carnivores and livestock in east africa.we examined 71 faecal samples of carnivores from queen elizabeth national park (qenp), uganda, for eggs of echinococcus species. thirty-nine faecal samples contained taeniid eggs. for species diagnosis, dna was isolated from a total of 1984 individual taeniid eggs. to differentiate eggs of echinococcus felidis from other taeniid taxa (including the closely related echinococcus granulosus sensu stricto), a restriction fragment length polymorphism (rflp)-pcr of the mitochondrial nad1 gene was deve ...200919275902
genetic characterization and phylogenetic position of echinococcus felidis (cestoda: taeniidae) from the african lion.echinococcus felidis had been described in 1937 from african lions, but was later included in echinococcus granulosus as a subspecies or a strain. in the absence of any genetic characterization, most previous records of this taxon from a variety of large african mammals remained unconfirmed due to the lack of diagnostic criteria and the possible confusion with the sympatric e. granulosus sensu stricto, echinococcus ortleppi and echinococcus canadensis. in this study, we obtained taeniid eggs fro ...200818062973
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