| in vitro antibacterial activities of three plants used in traditional medicine in sierra leone. | the antibacterial activities of the methanol and hot and cold aqueous extracts of the leaves of aspilia africana, ficus exasperata and mareya micrantha were bioassayed against three gram-negative and three gram-positive bacterial species: aerobacter aerogenes, agrobacterium tumefaciens, bacillus subtilis, clostridium sporogenes, escherichia coli and staphylococcus aureus. the methanol and aqueous extracts of the leaves of aspilia africana and mareya micrantha and the undiluted oil of m. micranth ... | 1990 | 2335960 |
| pharmacognosy and hypotensive evaluation of ficus exasperata vahl (moraceae) leaf. | there is already a literature report on the anti-ulcer effect of water extract of ficus exasperata. some communities in edo and delta states of nigeria use the decoction of the leaf as hypotensive crude drug. verification of this claim and also the microscopy and other pharmacognostic parameters which can be used to establish the identity of the leaf were carried out. the microscopy of the leaf powder revealed the presence of straight walled epidermal cells, cone or nail shaped trichomes or epid ... | 2007 | 18323249 |
| in vitro determination of the uterine stimulatory effect of the aqueous leaf extract of ficus exasperata. | the leaves of ficus exasperata vahl (moraceae) are used by traditional healers in southern nigeria to arrest pre-term contractions and are also used as an abortifacient in some parts of africa. | 2010 | 19833184 |
| antiarthritic and antioxidant effects of the leaf extract of ficus exasperata p. beauv. (moraceae). | leaf extracts of ficus exasperata p. beauv. (moraceae) are commonly used in ghanaian traditional medicine for the treatment of several pathological states including inflammatory disorders. the present study was undertaken to evaluate the antiarthritic effect of an ethanolic extract of f. exasperata (fee) in the freund's adjuvant-induced arthritis model in rats. since free radicals and reactive oxygen species are implicated in inflammatory joint diseases such as rheumatoid arthritis, the antioxid ... | 2010 | 21808547 |
| investigations of antimicrobial activity of some cameroonian medicinal plant extracts against bacteria and yeast with gastrointestinal relevance. | resistance against antibiotics of many bacteria is accumulating. therefore, searches for new substances with antimicrobial activity have become an urgent necessity. medicinal plants are frequently used in popular medicine as remedies for many infectious diseases (intestinal infection, malaria, tuberculosis, etc.). | 2012 | 22583961 |
| hypoglycaemic and hypotensive effects of ficus exasperata vahl. (moraceae) leaf aqueous extract in rats. | the hypotensive and hypoglycaemic effects of ficus exasperata (vahl) (family: moraceae) leaf aqueous extract (fee) were investigated in experimental rat models. in this study, spontaneously-hypertensive rats (shr) (type 1 diabetes), obese zucker (type 2 diabetes) and wistar rats were used. three (a, b and c) groups of rats, each group consisting of 10 rats, were used. group a wistar rats received distilled water in quantities equivalent to the volume of streptozotocin (stz) and fee administered ... | 2011 | 22468006 |
| a new sphingolipid and furanocoumarins with antimicrobial activity from ficus exasperata. | from the methanol extract of the stem bark of ficus exasperata, a new sphingolipid named ficusamide, (2s,3s,4r,11e)-2-[(2',3'-dihydroxyhexacosanoylamino)]-11-octadecene-1,3,4-triol (1), along with three known furanocoumarins, (s)-(-) oxypeucedanin hydrate (2), (r)-(+) oxypeucedanin hydrate (3), bergapten (5-methoxypsoralen) and six other known compounds, were isolated. their structures were characterized basing on spectroscopic methods and chemical evidence. compounds (1-3) were analyzed for the ... | 2012 | 22863713 |
| the leaves of ficus exasperata vahl (moraceae) generates uterine active chemical constituents. | in the search for new, safe and efficacious uterine active agents, the plant ficus exasperata was subjected to phytochemical screening and pharmacological analysis. | 2012 | 23266275 |
| antibacterial activity and phytochemical study of six medicinal plants used in benin. | the ethanol extracts obtained from psidium guajava, flacourtia flavescens boswellia dalzielii, ficus exasperata, pavetta corymbosa and hybanthus enneaspermus, six species traditionally used in benin to treat several infectious diseases, were evaluated for their in vitro antimicrobial activity against staphylococcus aureus, enteroccocus feacalis, escherichia coli and pseudomonas aeruginosa. the minimum inhibitory concentration of extracts was determinate using the microplate dilution method. the ... | 2011 | 21902057 |
| oxytocin inhibiting effect of the aqueous leaf extract of ficus exasperata (moraceae) on the isolated rat uterus. | the leaves of ficus exasperata vahl enum. pl. vahl (moraceae) are used by traditional healers in southern nigeria and some parts of africa to avoid preterm births. however, previous reports showed that the plant also exhibited uterine contractions at specific concentrations. this study is therefore aimed at investigating the purported uterine inhibitory aspect of the plant on the isolated rat uterus. the aqueous extract (aet) was tested on rhythmic spontaneous uterine contractions. concentration ... | 2011 | 21796936 |
| acute toxicity studies of the leaf extract of ficus exasperata on haematological parameters, body weight and body temperature. | the plant, ficus exasperata is popularly used in nigeria and in several parts of africa for a variety of ailments. | 2009 | 19429376 |
| toxicity and mutagenic activity of some selected nigerian plants. | the toxicity and mutagenic potential of most african plants implicated in the management of cancer have not been investigated. the ethanolic extracts of selected nigerian plants were subsequently studied using the brine shrimp lethality tests, inhibition of telomerase activity and induction of chromosomal aberrations in vivo in rat lymphocytes. morinda lucida root bark, nymphaea lotus whole plant and garcinia kola root were active in the three test systems. bryophyllum calycinum whole plant, ann ... | 2007 | 17707603 |
| evaluation of nigerian traditional medicines: ii. effects of some nigerian folk remedies on peptic ulcer. | antiulcer activity of four medicinal plants, diodia sarmentosa (whole plant), cassia nigricans (leaves), ficus exasperata (leaves) and synclisia scabrida (leaves), which are commonly used by the nigerian traditional healers for the treatment of peptic ulcer were investigated. acute toxicity tests were also carried out. the results revealed that the four extracts possess significant anti-ulcerogenic properties in a dose-dependent way. they protected rats from aspirin-induced ulcerogenesis, delaye ... | 1998 | 9741884 |
| effects of ficus exasperata vahl. (moraceae) leaf aqueous extract on the renal function of streptozotocin-treated rats. | the present study was undertaken to evaluate the possible reno-protective effect of ficus exasperata leaf aqueous extract (fee) in a rat experimental paradigm of diabetes mellitus. forty wistar rats (weighing 200-230 g) were divided into four (a, b, c, and d) groups, each group consisting of 10 rats. group a rats served as 'control' animals and received citrate buffer (ph 6.3) solution in quantities equivalent to intraperitoneally-administered volumes of streptozotocin (stz) and fee. diabetes me ... | 2012 | 22532177 |
| extracts of ficus exasperata leaf inhibit topical and systemic inflammation in rodents and suppress lps-induced expression of mediators of inflammation in macrophages. | the leaves of ficus exasperata are mashed and prepared as poultices that are placed on swellings, wounds, and arthritic joints to relieve swelling and pains by the igede tribal community of nigeria. the leaf and stalk are also squeezed and used to mitigate itching or inflammation. these claimed benefits inspired this study in which topical and systemic (acute, chronic) anti-inflammatory activities of a methanol/methylene chloride leaf extract of f. exasperata (mfe) were assessed in rodents. effe ... | 2013 | 23098056 |
| anthelmintic potential of three plants used in nigerian ethnoveterinary medicine. | the leaves of irvingia gabonensis baill. ex lanen (irvingiaceae), ficus exasperata vahl (moraceae), and vernonia amygdalina delile (asteraceae) are folklorically used in treating worm infestation in eastern nigeria. the anthelmintic potential of the ethanol extracts of the leaves of i. gabonensis, f. exasperata, and v. amygdalina was investigated. | 2013 | 23153212 |
| diuretic effects of aqueous extract of ficus exasperata vahl. leaves in rat. | ficus exasperata is widely used in african pharmacopoeia against hypertension and edema. the hypotensive effects of aqueous extract of f. exasperata leaves are reduced in the presence of atropine and methylene blue. the treatment of hypertension often requires the combination of antihypertensive drugs and diuretics substances. the aim of this study was to evaluate the effects of aqueous extract of f. exasperata leaves on urinary excretion in rat. single doses of this extract (50 mg kg(-1) b.wt.) ... | 2013 | 24511752 |
| phenolic compounds from sandpaper (ficus exasperata) leaf inhibits angiotensin 1 converting enzyme in high cholesterol diet fed rats. | sandpaper [ficus exasperata vahl (moraceae)] leaf has been reportedly used in folklore for the management/treatment of cardiovascular diseases with little/or no scientific basis for their action. this study sought to investigate the effect of dietary supplementation of sandpaper leaf on angiotensin-i converting enzyme (ace) activity in hypercholesterolemia as well as the effect of their phenolic extract on this enzyme in vitro. | 2014 | 25267581 |
| antioxidant and antibacterial activities of flavonoid glycosides from ficus exasperata vahl-holl (moraceae) leaves. | ficus exasperata vahl-holl (moraceae) leaves are used for infectious and inflammatory conditions in many west african countries. however, there is need for more phytochemical studies to justify the ethnomedicinal uses of the plant. | 2014 | 25371569 |
| wound-healing activity of the aqueous leaf extract and fractions of ficus exasperata (moraceae) and its safety evaluation on albino rats. | ficus exasperata have been reported to have wide applications in the treatment of many human diseases. however, its traditional use in the treatment of wounds has not been validated by any scientific study. also, its safety in the management of chronic disease conditions requires attention. we evaluated the wound-healing activity of the aqueous extract and fractions of f. exasperata, as well as its safety after subchronic oral administration. similar percentage of wound contraction was observed ... | 2014 | 25379466 |
| indomethacin-induced gastric ulceration in rats: ameliorative roles of spondias mombin and ficus exasperata. | spondias mombin linn (anacardiaceae) and ficus exasperata valh (moraceae) are botanicals with known phytotherapeutic potentials in the traditional system of medicine in the world. | 2016 | 25815713 |
| characterisation of the antiproliferative constituents and activity of ficus exasperata (vahl) on ovarian cancer cells -a preliminary investigation. | ovarian cancer is one of the most common gynaecological cancers today. this study therefore investigates the anticancer effects of ficus exasperata extracts and fractions on ovarian cancer cells. the antiproliferative activity of the crude extracts (1 mg/ml) was assessed using the mtt assay on a2780 (ovarian cancer) cell line. bio-activity guided fractionation was performed and preliminary identification was further achieved using high resolution mass spectrometry and nuclear magnetic resonance ... | 2017 | 28092975 |
| stabilization of palm oils by using ficus exasperata leaves in local processing methods. | this work was done to ascertain the efficacy of the local use of ficus exasperata leaves in processing palm oils to improve and stabilize the quality. palm oils were obtained from the ripe fruits of elaeis guineensis and elaeis guineensis var virescens, including ficus exasperata leaves in the traditional processing procedures--cooking and soaking the fruits in water. phytochemical analysis of the ficus leaves and the oils were performed. the quality of the oils were assessed in terms of saponif ... | 2004 | 15182838 |
| endogenous recipes for controlling arthropod ectoparasites of domestic poultry. | this study is a contribution to the inventory of medicinal plants and other methods used in controlling external parasitic diseases of backyard poultry in the localities of djougou and ouaké (department of donga, benin). it consists of a survey undertaken from december 2010 to march 2011 through visits and interviews with 210 poultry famers. the results indicate that 13 species of medicinal plants are used in controlling ectoparasites. annona senegalensis, tectona grandis, securidaca longepedunc ... | 2013 | 24252957 |
| an ethnobotanical survey of antidiabetic plants used by hausa-fulani tribes in sokoto, northwest nigeria. | sokoto is known for its diverse traditional medicinal wealth and international market of traditional medicines in africa. however, information of the folk knowledge, especially for the treatment of diabetes, is not documented. | 2015 | 26117532 |
| in vitro studies to assess the antioxidative, radical scavenging and arginase inhibitory potentials of extracts from artocarpus altilis, ficus exasperate and kigelia africana. | to justify the use of artocarpus altilis (a. altilis), ficus exasperata (f. exasperata) and kigelia africana (k. africana) in ethnomedicine for the treatment of several ailments and to evaluate the in vitro antioxidant, radical scavenging and arginase inhibitory potentials of these herbs and compared with catechin (standard). | 2014 | 25183137 |