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pathogenicity of a natural reassortant hantavirus cgrn9415 in newborn rats and newborn mice.to better understand the pathogenicity and infectivity of a natural reassortant cgrn9415 generated from hantaan virus (htnv) and seoul virus (seov), cgrn9415, htnv 76-118, and seov l99 were used to infect newborn kunming (km) mice and newborn wistar rats. in km mice, there was no statistic difference between the death rate with cgrn9415 and that with l99, while 76-118 killed all mice even at low dosage; cgrn9415 killed all infected rats like l99 at the dosage of 105 ffu while no death occurred i ...201222258864
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