| freshwater snail consumption and angiostrongyliasis in malaya. | a survey of the freshwater snails, pila scutata and bellamyia ingallsiana, as food consumed by the local population was carried out in peninsular malaysia. of these two species the first is preferred; the sizes favoured are between 25--40 mm. pila snails were found to be consumed by the three communities, viz. malay, chinese and indian, in different ways. the various methods of preparing the snails for consumption are described. p. scutata is an intermediate host of the rat-lung worm, angiostron ... | 1978 | 726037 |
| studies of angiostrongylus malaysiensis (nematoda, metastrongylidae) in peninsular malaysia: natural infection in freshwater snails and rodents in ricefields and infectivity experiments. | | 1977 | 887993 |
| angiostrongylus malaysiensis in indonesia. | | 1976 | 1025746 |
| the freshwater snail lymnaea rubiginosa as an experimental host of angiostrongylus malaysiensis: a preliminary report. | preliminary studies have shown that lymnaea rubiginosa, a common fresh-water snail in peninsular malaysia, which is easily colonized and reared in the laboratory, is a capable experimental intermediate host for angiostrongylus malaysiensis. overall 73% of the snails tested became infected following 6 hours exposure to infective rat faeces. higher infection rates, up to 100%, and heavier worm loads, occurred among the larger sized snails. snail attrition was low except when very heavy worm loads ... | 1976 | 1027105 |
| angiostrongylus malaysiensis from tuaran, sabah, with reference to the distribution of the parasite in malaysia. | a survey of angiostrongylus malaysiensis among wild rodent and molluscan hosts was made in the tuaran central agricultural research station and within the vicinity of tuaran, sabah. three of 19 rattus rattus diardii, one of 2 r. exulans and one r. argentiventer were found naturally infected with the parasite. in this survey 56 of 382 molluscs comprising of pila scutata, achatina fulica and two species of land slugs, laevicaulis alte and microparmarion malayanus, were found naturally infected wit ... | 1976 | 1030843 |
| worm burden and leukocyte response in angiostrongylus malaysiensis-infected rats: the influence of testosterone. | gonadectomized male albino rats aged 7 weeks were given 1.5 mg/kg testosterone propionate daily and inoculated with 50 third-stage larvae of angiostrongylus malaysiensis. the treatment significantly increased the number of larvae and adult worms recovered from the brain and pulmonary arteries, respectively, and the rats exhibited smaller thymus glands. the total numbers of leukocytes, monocytes, neutrophils, and especially eosinophils increased significantly post-infection, but the counts were h ... | 1992 | 1495916 |
| humoral immune response of balb/c mice to larval and adult worm antigens of angiostrongylus malaysiensis. | the development of angiostrongylus malaysiensis in balb/c mice and the humoral response due to it were studied by using the enzyme-linked immunosorbent assay (elisa) with adult worm and l3 antigens. the worms recovered from mice were seen in the brain tissue only, they failed to migrate to the lung as in the normal host (rats). the antibody titres of sera from infected mice, showed similar patterns in response to l3 antigen and to adult worm antigen. however, the highest antibody response could ... | 1989 | 2609213 |
| validity of angiostrongylus malaysiensis bhaibulaya and cross, 1971. | | 1974 | 4432097 |
| new hosts of angiostrongylus malaysiensis bhaibulaya and cross, 1971 in malaysia. | | 1974 | 4432098 |
| comparative studies of adult worms of angiostrongylus malaysiensis from three different regions in west malaysia. | | 1973 | 4749082 |
| angiostrongylus malaysiensis (nematoda: metastrongylidae), a new species of rat lung-worm from malaysia. | | 1971 | 5144154 |
| effect of diethylcarbamazine citrate on angiostrongylus malaysiensis infection in rats. | the aim of the study was to observe the effect of diethylcarbamazine citrate (dec) on angiostrongylus malaysiensis infection in albino rats. an attempt was made to vary the dose of dec and treat infected animals at the larval and adult stages of infection. the doses were varied with an aim at finding an effective dosage. animals were treated also during the pre-infection period to observe if the drug had any prophylactic properties. the results obtained show that dec given after infection was ef ... | 1983 | 6676503 |
| studies on the experimental chemotherapy of angiostrongylus malaysiensis infection in rats with mebendazole and levamisole. | the effect of levamisole hydrochloride and mebendazole on angiostrongylus malaysiensis infection in albino rats was studied. animals at different stages of infection were treated with various oral doses of levamisole and mebendazole with the aim of finding an effective treatment regime. levamisole was most effective for treating rats seven days after infection but its efficacy dropped as infection progressed. mebendazole given at a dose of 1 mg/kg for five days was more effective against early l ... | 1982 | 6926760 |
| chemotherapy and chemoprophylaxis of angiostrongylus malaysiensis infection in rats with levamisole and mebendazole. | the chemoprophylactic and chemotherapeutic effects of levamisole and mebendazole on angiostrongylus malaysiensis infection in rats were studied. both drugs were ineffective in preventing infection while the post-infection treatment showed 100% efficacy. furthermore, levamisole and mebendazole when given in combination appeared to have an antagonistic effect. | 1982 | 7160790 |
| selective interference with granulocyte function induced by echinostoma paraensei (trematoda) larvae in biomphalaria glabrata (mollusca). | various trematode larvae can interfere with the host snail's resistance to the same or unrelated trematode species, chiefly, it appears by interference with the function of the host's granulocytes. in biomphalaria glabrata infected with the trematodes, echinostoma paraensei, granulocytes lose their ability to encapsulate the larvae of trematodes to which the hosts were previously resistant. however, the granulocytes in these snails retain their ability to encapsulate injected latex spheres, or l ... | 1981 | 7328451 |
| seasonal prevalence of the helminth fauna of the wood rat rattus tiomanicus (miller) in west malaysia. | a helminthological examination of 367 wood rats, rattus tiomanicus, in an oil-palm. estate 24 miles north of kuala lumpur conducted during 1973 revealed 8 species of helminths: 5 nematodes. angiostrongylus malaysiensis (54.2% of the rats infected), hepatojarakus malayae (48.5%), nippostrongylus braziliensis (48.0%), gongylonema neoplasticum (0.3%), syphacia muris (17.7%); 3 cestodes, hymenolepis diminuta (6.0%), hymenolepis nana (7.6%), hydatigera taeniaeformis (cysticercus) (12.0%) and 1 pentas ... | 1980 | 7419126 |
| genetic variability in isozymes of angiostrongylus malaysiensis. | the genetic difference between angiostrongylus malaysiensis and a. cantonensis was assayed by electrophoretic analysis of isozymes. six enzymes were analyzed using 5% polyacrylamide gel electrophoresis. seven of 10 loci, namely gpi-1, gpi-2, hk-1, hk-2, mdh-1, mdh-2 and pgm-2, were shown to be polymorphic, but the remaining 3 loci, ldh, me and pgm-1, were not. both a. malaysiensis and a. cantonensis were polymorphic at 6 of the loci (p = 0.600) with heterozygosity h of 0.286 and 0.151, respectiv ... | 1994 | 7667723 |
| comparative infectivity and survival of first-stage larvae of angiostrongylus cantonensis and angiostrongylus malaysiensis. | angiostrongylus malaysiensis was isolated from wild rats rattus norvegicus in a seaport area of kitakyushu city, kyushu, japan in 1990. the infectivity and survival capacities of first-stage larvae of a. malaysiensis and angiostrongylus cantonensis were compared under various conditions. infectivity of first-stage larvae of the former in biomphalaria glabrata was much lower than that of the latter. in an exposure at various phs, and with various proteases and tissue homogenates of b. glabrata, t ... | 1995 | 7707198 |
| detection of angiostrongylus malaysiensis circulating antigen using monoclonal antibody-based enzyme-linked immunosorbent assay (mab-elisa). | three mabs 1c4.2d8, 1c4.2c4 and 1c4.1f5 were produced using sonicated adult worm antigens of angiostrongylus malaysiensis and they were found to be secreters of igg1. the mabs 1c4.2c4 and 1c4.2d8 were found to react with antigens of a. malaysiensis and cross-react with the closely related a. cantonensis but not with other helminths. a total of 108 human sera collected from orang asli (aborigenes) from grik, in the state of perak were tested for a. malaysiensis infection using the mab-elisa. mab ... | 1997 | 9656366 |
| neuro-angiostrongyliasis: unresolved issues. | angiostrongylus cantonensis, the rat lungworm, probably evolved with its hosts, members of the genus rattus and closely related species, in south-east asia. since its first discovery in rats in china and in a case of human infection in taiwan, the parasite has been found to infect humans and other mammals across a wide and ever-increasing territory, which now encompasses much of south-east asia, melanesia, polynesia and eastern australia. it has also established a foothold in africa, india, the ... | 2000 | 11113256 |
| molecular differentiation and phylogenetic relationships of three angiostrongylus species and angiostrongylus cantonensis geographical isolates based on a 66-kda protein gene of a. cantonensis (nematoda: angiostrongylidae). | the phylogenetic relationships and molecular differentiation of three species of angiostrongylid nematodes (angiostrongylus cantonensis, angiostrongylus costaricensis and angiostrongylus malaysiensis) were studied using the ac primers for a 66-kda protein gene of a. cantonensis. the ac primers successfully amplified the genomic dna of these angiostrongylid nematodes. no amplification was detected for the dna of ascaris lumbricoides, ascaris suum, anisakis simplex, gnathostoma spinigerum, toxocar ... | 2010 | 20566366 |
| molecular differentiation of angiostrongylus taxa (nematoda: angiostrongylidae) by cytochrome c oxidase subunit i (coi) gene sequences. | nematodes of the genus angiostrongylus are parasites of rodents and carnivores. they reside in the pulmonary or mesenteric arteries of their hosts. two species are pathogenic in humans -angiostrongylus cantonensis causes eosinophilic meningitis or meningoencephalitis, and angiostrongylus costaricensis produces abdominal angiostrongyliasis. in addition angiostrongylus malaysiensis may have the potential of being pathogenic in humans. the mitochondrial gene cytochrome c oxidase subunit i (coi) of ... | 2010 | 20654571 |
| cytochrome c oxidase subunit i haplotype reveals high genetic diversity of angiostrongylus malaysiensis (nematoda: angiostrongylidae). | the rat lungworm angiostrongylus malaysiensis is a metastrongyloid nematode parasite. it has been reported in malaysia, thailand, laos, myanmar, indonesia and japan. in this study, a. malaysiensis adult worms recovered from the lungs of wild rats in different geographical regions/provinces in thailand were used to determine their haplotype by means of the mitochondrial partial cytochrome c oxidase subunit i (coi) gene sequence. the results revealed high coi haplotype diversity of a. malaysiensis ... | 2017 | 28330511 |
| angiostrongylus cantonensis and a. malaysiensis broadly overlap in thailand, lao pdr, cambodia and myanmar: a molecular survey of larvae in land snails. | angiostrongylus cantonensis is a zoonotic nematode parasite causing human eosinophilic meningitis (or meningoencephalitis) worldwide. a closely related species, angiostrongylus malaysiensis, might also be a human pathogen. larvae were obtained from land snails in lao pdr, cambodia, myanmar and thailand. we sequenced two nuclear gene regions (nuclear ribosomal its2 and ssu rrna) and a portion of one mitochondrial gene (coi) from these larvae. angiostrongylus cantonensis and a. malaysiensis were i ... | 2016 | 27513930 |
| molecular phylogeography of angiostrongylus cantonensis (nematoda: angiostrongylidae) and genetic relationships with congeners using cytochrome b gene marker. | angiostrongylus cantonensis is an important emerging zoonotic parasite causing human eosinophilic meningitis (or meningoencephalitis) in many parts of the world. to-date there is only a single study using mitochondrial cytochrome b (cytb) gene to determine its genetic structure in eight geographical localities in thailand. the present study examined the molecular phylogeography of this rat lungworm and its phylogenetic relationship with congeners using cytb gene marker. a total of 15 cytb haplot ... | 2015 | 25930187 |
| complete mitochondrial genome of angiostrongylus malaysiensis lungworm and molecular phylogeny of metastrongyloid nematodes. | angiostrongylus malaysiensis is a nematode parasite of various rat species. when first documented in malaysia, it was referred to as a. cantonensis. unlike a. cantonensis, the complete mitochondrial genome of a. malaysiensis has not been documented. we report here its complete mitogenome, its differentiation from a. cantonensis, and the phylogenetic relationships with its congeners and other metastrongyloid taxa. the whole mitogenome of a. malaysiensis had a total length of 13,516bp, comprising ... | 2016 | 27207134 |
| biodiversity and macroparasitic distribution of the wild rat population of carey island, klang. | a study to determine the diversity and distribution of ectoparasites and endoparasites infesting wild rat population of carey island was carried out from june to december 2010. a total of 81 rats were captured from various locations on carey island. four rat species were identified namely, rattus tiomanicus (45.7%), rattus rattus diardii (25.9%), rattus argentiventer (16%) and rattus norvegicus (12.3%). low diversity of ecto and endoparasites were observed infecting the rodent population with 8 ... | 2013 | 23959485 |
| helminth communities from two urban rat populations in kuala lumpur, malaysia. | the prevalence of parasitic infections among commensal animals such as black and brown rats in many tropical countries is high and in comparison with studies on rodents in temperate climates, little is known about the community structure of their parasites. rodent borne parasites pose threats to human health since people living in close proximity to rodent populations can be exposed to infection. | 2012 | 22397763 |