Publications

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[monkeys and lower primates as natural and experimental hosts of the african lung flukes, paragonimus africanus and p. uterobilateralis (author's transl)]. 1977407679
[radiographic findings in rhesus monkeys experimentally infected with african lung flukes (paragonimus africanus and p. uterobilateralis) (author's transl)].the radiographic pattern in the course of experimentally infected rhesus monkeys with the two african fluke species paragonimus africanus and p. uterobilateralis consist of hilar dilatation, streaky, patchy or diffuse shadows, cavities, atelectases and pleural reactions. all animals develop changes in both lungs, those infected with p. africanus preferentially in the lower parts. there is an obvious correlation with the autopsy findings in the same animals as well as radiological features in hum ...1977407680
[histopathological alterations in rhesus monkeys after experimental infections with african lung flukes (paragonimus africanus and p. uterobilateralis) (author's transl)].histopathological observations in monkeys experimentally infected with african lung flukes are reported. the observations were made on 3 rhesus monkeys, infected with paragonimus africanus from west-cameroon, and on 5 rhesus monkeys, infected with p. uterobilateralis from eastern nigeria. for comparison, the lung of a naturally infected drill (mandrillus leucophaeus) was included in the study. the following lesions were found: formation of parasite cavernae, intense infiltration of the cavern wa ...1977407681
[paragonimiasis of the lung].paragonimiasis results from infection with a trematode worm, p. westermani or, less commonly, one of the many of the other paragonimus species (for instance: paragonimus africanus). it usually affects the lung with manifestation of chronic cough, hemoptysis and roentgenographic infiltrates, alterations that can be difficult to distinguish from the lesions of tuberculosis. the diagnosis is established by the finding of paragonimus eggs in the sputum or stool. on the basis of a case report on pulm ...19873673120
[2 new paragonimus species from west africa: paragonimus africanus and paragonimus uterobilateralis (troglotrematidae; trematoda)]. 19654954791
an epidemiological study of pleuropulmonary paragonimiasis among pupils in the peri-urban zone of kumba town, meme division, cameroon.paragonimiasis have previously been reported in two zones of the southwest province of cameroon including the kupe mountain and mundani foci. the aim of this study was to investigate the presence and epidemiology of paragonimiasis in the peri-urban zone of kumba, meme division, located about 50 km away from the kupe mountain focus.200314678562
first findings on the seroepidemiology of human paragonimosis at the anti-tuberculosis centre of divo, repubuc of ivory coast (west africa).an epidemiological study was carried out in 2004-2005 at the anti-tuberculosis centre of divo (ivory coast) to collect sera from patients who consulted for tuberculosis suspicion and to estimate the seroprevalence of human paragonimosis in the context of a systematic screening. no paragonimus egg was found in the stools and/or sputa of the 167 persons investigated. in contrast, 41 sera were ascertained with antibodies against paragonimus africanus using elisa testing. as the optical density (od) ...200818642509
isolation of microcercous cercariae from snails caught in an endemic focus of paragonimus uterobilateralis in liberia, west africa.microcercous cercariae have been recovered from the snail homorus (striosubulina) striatella rang. which were collected in a focus of human lung fluke disease in liberia, west africa, and are here described. metacercariae of paragonimus uterobilateralis were isolated from freshwater crabs (liberonautes latidactylus) captured at the same location, and at the same time, as the infected snails. the dimensions of the liberian cercariae have been found to differ markedly from those of a cercaria from ...19892740730
endemic human paragonimiasis in equatorial guinea. detection of the existence of endemic human paragonimiasis in equatorial guinea as a result of an integrated sanitary programme.between february and april 1990 the first five cases of human paragonimiasis, tentatively due to paragonimus africanus, have been detected in equatorial guinea, thanks to the normal activities of the national schistosomiasis project and its coordination with the national tuberculosis project.19911816673
a primate, mandrillus leucophaeus, as natural host of the african lung flukeparagonimus africanus in west-cameroon.paragonimus africanus was recovered from a free-living drill (mandrillus leucophaeus) in cameroon. this is the first record on the natural infection of a non-human primate with lung flukes in africa.19751162736
[on the distribution of the lung flukes, paragonimus africanus and p. uterobilateralis, in the south west province of cameroon and in eastern nigeria as determined by examination of the intermediate crab hosts for infection with metacercariae (author's transl)].during 1973-75 the distribution of the lung flukes, paragonimus africanus and p. uterobilateralis, was studied in south west-cameroon and in eastern nigeria, on the basis of parasitological examinations of the intermediate crab hosts sudanonautes africanus, s. pelii, and s. aubryi, belonging to the family potamonidae. 1000 freashwater crabs from 80 localities were examined for prevalence and intensity of infection with paragonimus methacercariae. in cameroon s. pelii was found to be a new interm ...1977871036
properties of 3',5'-cyclic-amp phosphodiesterase from paragonimus africanus metacercariae.3',5'-cyclic-amp 5'-nucleotidohydrolase (camp phosphodiesterase, ec 3.1.4.17) was partial purified from metacercariae of paragonimus africanus. the enzyme activity absolutely depends on mg2 or mn2+. the ph-optimum of the camp phosphidiesterase was found at ph 8.0. the michaelis constant for camp was determined to be 5 x 10(-6) m. papaverine deoxyadenosine, theophylline and adenosine were found to be competitive inhibitors of the enzyme activity. the inhibitor constants were calculated to be 13 x ...197610655
lung fluke (paragonimus africanus) infects nigerian red-capped mangabeys and causes respiratory disease.eggs of the lung fluke genus paragonimus were detected in red-capped mangabeys (cercocebus torquatus) in nigeria. we assess the role of these primates as potential sylvatic hosts and the clinical effects of the parasite on monkeys. dna sequenced from eggs in feces were 100% identical in the its2 region to paragonimus africanus sequences from humans in cameroon. paragonimus-positive monkeys coughed more than uninfected monkeys. experimental de-worming led to reduction in parasite intensity and a ...201526543803
paragonimiasis in cameroon: molecular identification, serodiagnosis and clinical manifestations.paragonimiasis is a common parasitic zoonosis in cameroon and neighbouring countries in western africa. serum, sputum and faecal samples were collected in an endemic area of south west province, cameroon, after administration of a questionnaire to identify individuals with appropriate symptoms and histories. microscopic examination revealed eggs in sputum from 16 people, but none in any faecal sample. these 16 were among the 25 and 26 people, respectively, positive by elisa and by immunoblot usi ...200918992906
[paragonimiasis in cameroon: clinicoradiologic features and treatment outcome].a prospective study of paragonimiasis was undertaken from september 1992 to july 1997 in the mount kupe zone of the southwest province of cameroon. in a group of 2700 subjects, 312 presenting one or more signs of paragonimiasis underwent testing to detect paragonimus africanus eggs in sputum and stools. eggs were found in 30 subjects (9.61%). these patients underwent chest x-rays to assess radiological lesions due to paragonimiasis before and after treatment with praziquantel. symptoms included ...200312910655
identification of african paragonimidae by multivariate analysis of the eggs.a study of metacercariae and adult paragonimidae revealed the existence in west-africa of four species, of which two are largely recorded in literature (paragonimus africanus and paragonimus uterobilateralis), one was suspected (paragonimnus westermani-like) and one remained unrecorded in africa (euparagonimus sp). among the two last ones, p. westermani-like was probably confused with p. africanus, and euparagonimus sp. with p. uterobilateralis. p. westermani-like adult worms differed from p. af ...19999924963
pulmonary paragonimiasis in cameroon.paragonimus africanus has been known to be endemic in the bakossi area of meme division of cameroon since it was first described in 1952. after a lapse of 25 years, exploratory work was undertaken in the area (but not in the same villages) to study the prevalence of the disease, to record the common presenting symptoms, to make a number of paraclinical examinations, to assess the beliefs and attitudes of the people towards the disease and the possible reasons for its persistent endemicity in tha ...19827164143
application of different paragonimus antigens to immunodiagnosis of human lung fluke infection.utilizing enzyme immunoassay, paragonimus africanus, p. uterobilateralis, p. ecuadoriensis and p. westermani antigens were tested with regard to their reactivity to sera from patients infected with paragonimus africanus, p. uterobilateralis, p. ecuadoriensis, fasciola hepatica, opisthorchis viverrini, different schistosomes, cysticercus cellulosae, nematodes and from patients with nonparasitic diseases as well as from healthy blood donors. simultaneous application of paragonimus antigens to each ...19846542396
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