| detection of a new bat gammaherpesvirus in the philippines. | a new bat herpesvirus was detected in the spleen of an insectivorous bat (hipposideros diadema, family hipposideridae) collected on panay island, the philippines. pcr analyses were performed using consensus-degenerate hybrid oligonucleotide primers (codehops) targeting the herpesvirus dna polymerase (dpol) gene. although we obtained pcr products with codehops, direct sequencing using the primers was not possible because of high degree of degeneracy. direct sequencing technology developed in our ... | 2009 | 19452269 |
| a novel bat herpesvirus encodes homologues of major histocompatibility complex classes i and ii, c-type lectin, and a unique family of immune-related genes. | herpesviruses or herpesviral sequences have been identified in various bat species. here, we report the isolation, cell tropism, and complete genome sequence of a novel betaherpesvirus from the bat miniopterus schreibersii (mshv). in primary cell culture, mshv causes cytopathic effects (cpe) and reaches peak virus production 2 weeks after infection. mshv was found to infect and replicate less efficiently in a feline kidney cell, crfk, and failed to replicate in 13 other cell lines tested. sequen ... | 2012 | 22623774 |