| genetic investigation of novel hantaviruses causing fatal hps in brazil. | although hantavirus pulmonary syndrome (hps) was discovered in north america in 1993, more recent investigations have shown that the disease is a much larger problem in south america, where a greater number of cases and hps-associated viruses have now been detected. here we describe the genetic investigation of three fatal hps cases from brazil, including a 1995 case in castelo dos sonhos (cas) in the state of mato grosso and two 1996 cases in the counties of araraquara (ara) and franca (fra), i ... | 1999 | 10534737 |
| hantavirus pulmonary syndrome, central plateau, southeastern, and southern brazil. | hantavirus pulmonary syndrome (hps) is an increasing health problem in brazil because of encroachment of sprawling urban, agricultural, and cattle-raising areas into habitats of subfamily sigmodontinae rodents, which serve as hantavirus reservoirs. from 1993 through june 2007, a total of 884 cases of hps were reported in brazil (case-fatality rate 39%). to better understand this emerging disease, we collected 89 human serum samples and 68 rodent lung samples containing antibodies to hantavirus f ... | 2009 | 19331732 |
| genetic characterization of a juquitiba-like viral lineage in oligoryzomys nigripes in rio de janeiro, brazil. | hantaviruses, family bunyaviridae, are rodent-borne rna viruses that have caused cases of hantavirus cardiopulmonary syndrome (hcps) in various regions of the americas. there are five hantaviral lineages associated with hcps in brazil: juquitiba virus (juqv), araraquara virus (arav), laguna negra-like virus (lnv), castelo dos sonhos virus (casv), and anajatuba virus (anajv). three additional hantaviruses have been described in rodents alone: rio mearim virus, jaborá virus, and a hantavirus linea ... | 2009 | 19660427 |
| characterization of juquitiba virus in oligoryzomys fornesi from brazilian cerrado. | the juquitiba virus, an agent of hantavirus cardiopulmonary syndrome, is one of the most widely distributed hantavirus found in south america. it has been detected in oligoryzomys nigripes, akodon montensis, oxymycterus judex, akodon paranaensis in brazil and in o. nigripes, oryzomys sp. and oligoryzomys fornesi rodents in argentine, paraguay and uruguay. here, we report the genomic characterization of the complete s segment from the juquitiba strain, isolated from the lung tissues of o. fornesi ... | 2014 | 24674957 |
| detection of different south american hantaviruses. | hantaviruses are the etiologic agents of hemorrhagic fever with renal syndrome (hfrs) in old world, and hantavirus pulmonary syndrome (hps)/hantavirus cardiopulmonary syndrome (hcps), in the new world. serological methods are the most common approach used for laboratory diagnosis of hcps, however theses methods do not allow the characterization of viral genotypes. the polymerase chain reaction (pcr) has been extensively used for diagnosis of viral infections, including those caused by hantavirus ... | 2015 | 26220480 |
| co-circulation in a single biome of the juquitiba and araraquara hantavirus detected in human sera in a sub-tropical region of brazil. | hantaviruses is an emerging infectious disease. although hcps has been reported in several regions of brazil, more cases of hcps have recently been reported in minas gerais than in any other state. in 2009, we analyzed 27 samples presenting antibodies against hantaviruses. these samples originated from 688 symptomatic patients, as determined based on the hemorrhagic fever protocol. a subsequent sybr green-based real-time rt-pcr demonstrated the presence of the virus in 22 of the samples. among t ... | 2015 | 25678450 |
| hantavirus pulmonary syndrome in a highly endemic area of brazil. | hantavirus pulmonary syndrome (hps) is the most frequently reported fatal rodent-borne disease in brazil, with the majority of cases occurring in santa catarina. we analysed the clinical, laboratory and epidemiological data of the 251 confirmed cases of hps in santa catarina in 1999-2011. the number of cases ranged from 10 to 47 per year, with the highest incidences in 2004-2006. gastrointestinal tract manifestations were found in >60% of the cases, potentially confounding diagnosis and leading ... | 2016 | 26464248 |
| ecological study of hantavirus infection in wild rodents in an endemic area in brazil. | a 3-year ecological study of small mammals was carried out in an endemic area for hantavirus pulmonary syndrome in the state of santa catarina in southern brazil. a total of 994 rodents of 14 different species corresponding to the subfamilies of sigmodontinae, murinae, eumysopinae, and caviinae were captured during 2004-2006. oligoryzomys nigripes and akodon montensis were the most abundant species and showed a clear seasonal pattern with higher population sizes during the winter. rodent populat ... | 2014 | 24291677 |
| phylogenetic analysis of the s segment from juquitiba hantavirus: identification of two distinct lineages in oligoryzomys nigripes. | the purpose of this study was to investigate the phylogenetic relationship of the juquitiba virus (juqv) carried by oligoryzomys nigripes in endemic and non-endemic areas of brazil. wild rodents infected with the juquitiba virus (juqv) were sampled from a non-hantavirus cardiopulmonary syndrome endemic area in brazil. three strains from o. nigripes were identified by the sequencing of the complete s segment and compared to previous studies of juqv available in genbank. the phylogenetic analysis ... | 2013 | 23751399 |
| co-circulation of araraquara and juquitiba hantavirus in brazilian cerrado. | hantavirus cardiopulmonary syndrome is an emerging serious disease in the americas, transmitted from wild rodents to humans through inhalation of aerosol containing virus. herein, we characterized two distinct hantaviruses circulating in rodent species form central plateau, midwestern region of brazil in the cerrado (savanna-like) biome, an area characterized by small trees and grasses adapted to climates with long dry periods. in this study, we identified the co-circulation of the araraquara vi ... | 2017 | 28856421 |