| analysis of human rotavirus g1p[8] strains by rflp reveals higher genetic drift in the vp7 than the vp4 gene during a 4-year period in mexico. | several studies have demonstrated that rotaviruses of the g1p[8] genotype are among the most important worldwide. sequence analysis of g1p[8] strains has revealed high genetic variability of vp4 and vp7 genes. the aim of this study was to investigate by restriction fragment length polymorphism (rflp) analysis the genetic variability of the vp7 and vp4 genes within rotaviruses of the g1p[8] genotype. a total of 60 rotavirus-positive fecal samples genotyped as g1p[8], were collected from children ... | 2006 | 17030065 |
| genetic variation of prevalent g1p[8] human rotaviruses in south korea. | the human rotavirus g1p[8] strain is one of the most common rotaviruses worldwide, including korea. six korean g1p[8] human rotaviruses, isolated using cell culture techniques, were characterized on the basis of sequence differences in vp7, vp4, vp6, and nsp4 genes to elucidate the evolutionary relationships in the community. all strains had a long rna electropherotype, supported by vp6 gene analysis, clearly associated with subgroup ii specificity. the phylogenetic analysis of vp7 gene sequence ... | 2010 | 20336735 |
| sequence analysis of vp4 genes of wild type and culture adapted human rotavirus g1p[8] strains. | to conduct a comparative analysis of the vp4 gene sequences of indian wild type (06361, 0613158, 061060 and 0715880) and cell culture adapted (06361-ca, 0613158-ca, 061060-ca and 0715880-ca) g1p[8] rotavirus strains. | 2011 | 21803305 |
| rotavirus infection: a perspective on epidemiology, genomic diversity and vaccine strategies. | for centuries, acute diarrhea has been a major cause of death in young children worldwide, and until 1973, before rotavirus was discovered; no infectious agents could be identified in about 80% of patients admitted to hospital with severe dehydrating diarrhea. rotaviruses have now been shown to cause 40-50% of severe acute diarrhea in young children worldwide in both developing and developed countries. more than 600,000 young children die and approximately 2.4 million hospitalize annually from r ... | 2011 | 23637497 |