| complete genomic sequences, a key residue in the spike protein and deletions in nonstructural protein 3b of us strains of the virulent and attenuated coronaviruses, transmissible gastroenteritis virus and porcine respiratory coronavirus. | transmissible gastroenteritis virus (tgev) isolates that have been adapted to passage in cell culture maintain their infectivity in vitro but may lose their pathogenicity in vivo. to better understand the genomic mechanisms for viral attenuation, we sequenced the complete genomes of two virulent tgev strains and their attenuated counterparts: virulent tgev miller m6 and attenuated tgev miller m60 and virulent tgev purdue and attenuated tgev purdue p115, together with the isu-1 strain of porcine ... | 2007 | 17023013 |