| absence of genotoxicity of a phytotherapeutic extract from stryphnodendron adstringens (mart.) coville in somatic and germ cells of drosophila melanogaster. | stryphnodendron adstringens (mart.) coville, a medicinal plant that grows in the "cerrados" (a savanna ecosystem) of brazil, popularly known as "barbatimão," is an important source of tannins (polyphenols). in brazil, it is used in industry (mainly as vegetable tanning) and also in traditional medicine for the treatment of various diseases. in the present study, a phytotherapeutic extract from s. adstringens stem bark was evaluated for mutagenic and recombinagenic effects using the wing spot tes ... | 2003 | 12717784 |
| analysis of the polyphenols content in medicinal plants based on the reduction of cu(ii)/bicinchoninic complexes. | a spectrophotometric method is proposed for the determination of the polyphenols content in aqueous extracts of plants. the method is based on the reduction of cu(ii) to cu(i) by polyphenols, in the presence of bicinchoninic acid in a buffered medium (ammonium acetate, ph 7.0) with the formation of cu(i)/bca complexes. a calibration curve of absorbance (at 558 nm) vs tannic acid concentration is linear (r = 0.995; n = 7) with tannic acid from 0.1 to 0.7 micromol l(-1). the limit of detection and ... | 2009 | 19899763 |
| Inhibitory Activity of a-Amylase and a-Glucosidase by Plant Extracts from the Brazilian Cerrado. | Diabetes mellitus is the most common disease in the world. One therapeutic approach for treating diabetes is inhibition of a-amylase and a-glucosidase activities to reduce postprandial blood glucose levels. IN VITRO tests showed that several plant extracts from Brazilian cerrado species can inhibit the activity of a-amylase and a-glucosidase. The extracts of EUGENIA DYSENTERICA, STRYPHNODENDRON ADSTRINGENS, POUTERIA CAIMITO, POUTERIA RAMIFLORA, and POUTERIA TORTA showed strong a-amylase ... | 2011 | 22134849 |
| in vitro antimicrobial activity of brazilian medicinal plant extracts against pathogenic microorganisms of interest to dentistry. | this study evaluated the susceptibility of oral pathogenic microorganisms candida albicans, streptococcus mutans, staphylococcus aureus, and aggregatibacter actinomycetemcomitans to brazilian medicinal plant extracts of schinus terebinthifolius (aroeira), croton campestris (velame), lafoensia pacari (pacari), centaurium erythraea (centáurea), stryphnodendron adstringens (barbatimão), and anacardium humile (cajuzinho-docerrado), as compared to standardized antimicrobial agents (nystatin, chloramp ... | 2011 | 20862640 |
| safety evaluation of proanthocyanidin polymer-rich fraction obtained from stem bark of stryphnodendron adstringens (barbatimao) for use as a pharmacological agent. | the widespread use of medicinal plants among the brazilian population warrants an assessment of the potential risks associated with their intake. stryphnodendron adstringens (barbatimão) is one of the most frequently used medicinal plants in brazil, and the risks associated with its use have yet to be investigated. this study evaluated the genotoxic safety of the use of the proanthocyanidin polymer-rich fraction (f2) of stem bark of s. adstringens. the micronucleus test with 750, 1500, and 2250 ... | 2010 | 20655967 |
| [effects of silver sulfadiazine, ipê roxo (tabebuia avellanedae) extract and barbatimão (stryphnodendron adstringens) extract on cutaneous wound healing in rats]. | morphological study of effects of silver sulfadiazine, tabebuia avellanedae (ipê-roxo) extract and stryphnodendron adstringens (barbatimão) extract on cutaneous wound healing was done. | 2010 | 20414576 |
| activity of tannins from stryphnodendron adstringens on cryptococcus neoformans: effects on growth, capsule size and pigmentation. | stryphnodendron adstringens (mart.) coville, leguminosae, also known in brazil as barbatimão, is rich in tannins and many flavan-3-ols and proanthocyanidins such as prodelphinidins and prorobinetinidins. previous studies have demonstrated several pharmacological properties of tannins from barbatimão, including anti-candidal activity. | 2009 | 19891776 |
| evaluation of the antifungal potential of brazilian cerrado medicinal plants. | therapeutic limitations, development of fungal drug resistance, drug-related toxicity, drug interactions and insufficient bioavailability of the currently available antifungal drugs have made the development of drugs necessary that would be able to treat the emerging fungal infections. the cerrado is the second greater biome of brazil and it was identified as one of the most distinguished biomes of south america, becoming an important source of innovative vegetal molecules to treat several condi ... | 2009 | 19207849 |
| double-blind, randomized, placebo-controlled trial of a cream containing the stryphnodendron adstringens (martius) coville bark extract for suppressing terminal hair growth. | excess of terminal hair can be defined as excessive hair that appears in male-like pattern in women. some experts consider this condition as a result of an atypical relationship between levels of circulating androgens and sensitivity of androgen receptors in hair follicles to circulating androgens. | 2009 | 19192016 |
| influence of tannins from stryphnodendron adstringens on growth and virulence factors of candida albicans. | the main objective of this work was to investigate the antifungal activity of a crude extract, fractions and subfractions from stryphnodendron adstringens (mart.) coville, known as 'barbatimão'. | 2006 | 16973655 |
| antiviral effect of guazuma ulmifolia and stryphnodendron adstringens on poliovirus and bovine herpesvirus. | crude extract (ce) and aqueous (aqf) and ethyl acetate (etoacf) fractions of guazuma ulmifolia lam., sterculiaceae and the corresponding aqf, etoacf of stryphnodendron adstringens (mart.) coville, leguminosae were tested for their antiviral activity against poliovirus 1 (p-1) and bovine herpesvirus 1 (bhv-1) in hep-2 cultured cells. the antiviral activity was monitored by plaque assay and immunofluorescence assay (ifa) under virucidal and therapeutic protocols. the therapeutic protocol demonstra ... | 2006 | 16754999 |
| biological effects of extracts obtained from stryphnodendron adstringens on herpetomonas samuelpessoai. | we report the effect of stryphnodendron adstringens on the trypanosomatid herpetomonas samuelpessoai. the parasites were grown at 28 degrees c in a chemically defined medium containing crude extract and fractions at concentrations from 100 to 5000 microg/ml obtained from s. adstringens. concentrations of 500, 1000, 2500, and 5000 microg/ml both crude extract and semi-purified fraction progressively inhibited the protozoans' growth. at a concentration of 100 microg/ml, crude extract or a semi-pur ... | 2005 | 16113888 |
| effect of stryphnodendron adstringens (barbatimão) on energy metabolism in the rat liver. | the action of a barbatimão extract on hepatic energy metabolism was investigated using isolated mitochondria and the perfused rat liver. in mitochondria the barbatimão extract inhibited respiration in the presence of adp and succinate. stimulation occurred, however, after adp phosphorylation (state iv respiration). the adp/o and respiratory control ratios were reduced. the activities of succinate-oxidase, nadh-oxidase and the oxidation of ascorbate were inhibited. the atpase of intact mitochondr ... | 2003 | 12697381 |
| toxicological studies on stryphnodendron adstringens. | this study was carried out to determine the acute toxicity of total barbatimão extract (ld(50)) after oral administration to mice, and its effect on certain biochemical parameters in plasma of rats after 30 days of administration. the ld(50) value of the extract was 2699 mg/kg. a daily oral administration of extracts at 800 and 1600 mg/kg doses for 30 days caused a decrease in body weight, thymic involution, and an increase of plasma glucose and aspartate aminotransferase levels in the animals. ... | 2002 | 12413713 |
| tannin composition of barbatimão species. | a comparative study of tannin composition of three species known as barbatimão (stryphnodendron adstringens, stryphnodendron polyphyllum and dimorphandra mollis) was developed by tlc, hydrolysis followed by pc, and colorimetry. principal component analysis of the data obtained showed strong differentiation between the genus dimorphandra and stryphnodendron. additionally, barks from the two stryphnodendron sp. also presented considerable differences in the tannin structure. | 2002 | 12234571 |
| the acetone soluble fraction from bark extract of stryphnodendron adstringens (mart.) coville inhibits gastric acid secretion and experimental gastric ulceration in rats. | the acetone soluble fraction from a crude methanol extract of stryphnodendron adstringens stem bark (afsab) was evaluated in acute (ethanol, indomethacin and hypothermic restraint-stress) and chronic (acetic acid) models of gastric ulceration and on basal and bethanechol-stimulated gastric acid secretion in rats. rats pretreated orally with afsab at doses of 400 and 800 mg/kg showed significant decreases of gastric lesion scores in ethanol (62% and 98%) and hypothermic restraint-stress (89% and ... | 2002 | 12203261 |
| gastric antiulcerogenic effects of stryphnodendron adstringens in rats. | the antiulcer activity of the total extract and the fractions of stryphnodendron adstringens was studied in rats and compared with that of cimetidine. ulcers were induced in rats by means of three experimental models: acute stress, acidified-ethanol and indomethacin. the total extract and the fractions were found to have significant antiulcer activity in the case of the acute stress and acidified-ethanol models. these findings support the use of s. adstringens extracts in the treatment of gastri ... | 1999 | 10353177 |