Publications

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enteric infection of a goat with enterohemorrhagic escherichia coli (o103:h2). 19921616990
structural determination of the o-antigenic polysaccharide of enteropathogenic escherichia coli o103:h2.the structure of the antigenic o-polysaccharide isolated from the lipopolysaccharide produced by enterohemorrhagic escherichia coli o103:h2 was determined and shown to be composed of d-glucose (1 part), 2-acetamido-2-deoxy-d-glucose (2 parts), 2-acetamido-2-deoxy-d-galactose (1 part), and 3-deoxy-3-(r)-3-hydroxybutyramido-d-fucose (1 part). from the results of methylation analysis, smith-type periodate oxidation degradation studies, and the use of one- and two-dimensional (1)h and (13)c nmr spec ...201020555398
phenotypic and genotypic characterization of verotoxin-producing escherichia coli o103:h2 isolates from cattle and humans.characterization of important non-o157 verotoxin-producing escherichia coli (vtec) has lagged considerably behind that of o157:h7 strains. this study characterized 91 vtec o103:h2 strains from bovine and human sources and of north american and european origins by virulence or putative virulence genes, pulsed-field gel electrophoresis (pfge) patterns, plasmid profiles, antimicrobial resistance, and colicin production. all strains were positive for vt1 and eae-epsilon; 97% were positive for ehxa; ...200818768648
characterization of verotoxin-encoding phages from escherichia coli o103:h2 strains of bovine and human origins.the objectives of this study were to induce and characterize verotoxin-encoding phages from a collection of 91 verotoxin-producing escherichia coli (vtec) o103:h2 strains of human and bovine origins. all the strains carried the vt1 gene, and two carried the vt2 gene as well. the phages were induced by uv irradiation and characterized by dna restriction fragment length polymorphism (rflp), genome size, morphology, and q and p genes, characteristic of lambdoid phages. a total of 32 vt-positive pha ...200818552193
tracing shigatoxigenic escherichia coli o103, o145, and o174 infections from farm residents to cattle.severe diarrheal infections caused by shigatoxigenic escherichia coli o103:h2:stx(1):eae-epsilon:ehx, o145:h28:stx(1):eae-gamma:ehx (two cases in a family), and o174:h21:stx(2c) in farm residents were traced to cattle. molecular methods were applied to the isolation and characterization of the strains. the causative strains were also isolated from cattle samples 1 or 4 months later.200717804658
clonal diversity of shiga toxin-producing escherichia coli o103:h2/h(-) in germany.shiga toxin producing escherichia coli o103:h2/h(-) belong to the third most frequently isolated ehec serotypes in germany following isolates of o157:h7/h(-) and o26:h11/h(-). a total of 145 respective e. coli 103 isolates from single cases of diarrhoea and haemolytic uremic syndrome (hus) in 1997-2000 were characterised by a range of molecular subtyping methods (pfge, p-gene profiling, ribotyping, electrotyping) and phage typing in order to analyse their genetic relatedness and the practicabili ...200212798005
haemorrhagic colitis due to escherichia coli o103:h2 associated with infliximab therapy in a patient with rheumatoid arthritis. 200211934982
first bovine and ovine isolations of shiga toxin-producing escherichia coli o103:h2 in australia. 200111349417
[a familial outbreak of verotoxin-producing escherichia coli o103:h2 infection in which a calf was the suspected infectious source].a familial outbreak of verotoxin-producing escherichia coli (vtec) infection occurred in july 1996 in akita prefecture. four vtec strains harboring vt-1 and eaea genes were isolated from three patients and a calf, breeding farm for which was located as close as 4 meters from the house where the patients lived in. all of the 4 vtec isolates were serotyped as o63:h2 using commercially available sera kits. however, a patient isolate, ec-281, was serotyped as 0103:h2 at the international escherichia ...19989745220
hemolytic-uremic syndrome in a six-year-old girl after a urinary tract infection with shiga-toxin-producing escherichia coli o103:h2. 19968687518
identification of a clone of escherichia coli o103:h2 as a potential agent of hemolytic-uremic syndrome in france.in a french multicenter study, six verocytotoxin-producing escherichia coli strains were isolated from the stools of 6 of 69 children suffering from hemolytic-uremic syndrome. all strains belonged to serotype o103:h2, a serotype commonly associated with diarrhea in weaned rabbits in france. to determine whether the strains from humans and rabbits were genetically related, they were compared by analyzing their esterase electropherotypes and the restriction fragment length polymorphisms of the rib ...19938432815
identification of a clone of escherichia coli o103:h2 as potential agent of hemolytic-uremic syndrome in france. 19948195410
production of verotoxin and distribution of o islands 122 and 43/48 among verotoxin-producing escherichia coli o103:h2 isolates from cattle and humans.this study investigated variations in the occurrence of markers of o islands 122 and 43/48 and in verotoxin 1 production in 91 verotoxin-producing escherichia coli (vtec) o103:h2 strains of bovine and human origins. none of the genes that were investigated appear to be virulence indicators for human o103:h2 vtec.200918997029
human intestinal tissue tropism of intimin epsilon o103 escherichia coli.human intestinal in vitro organ culture was used to assess the tissue tropism of human isolates of escherichia coli o103:h2 and o103:h- that express intimin epsilon. both strains showed tropism for follicle associated epithelium and limited adhesion to other regions of the small and large intestine. this is similar to the tissue tropism shown by intimin gamma enterohaemorrhagic (ehec) o157:h7, but distinct from that of intimin alpha enteropathogenic (epec) o127:h6.200312586409
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