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zika virus outbreak on yap island, federated states of micronesia.in 2007, physicians on yap island reported an outbreak of illness characterized by rash, conjunctivitis, and arthralgia. although serum from some patients had igm antibody against dengue virus, the illness seemed clinically distinct from previously detected dengue. subsequent testing with the use of consensus primers detected zika virus rna in the serum of the patients but no dengue virus or other arboviral rna. no previous outbreaks and only 14 cases of zika virus disease have been previously d ...200919516034
present and future arboviral threats.arthropod-borne viruses (arboviruses) are important causes of human disease nearly worldwide. all arboviruses circulate among wild animals, and many cause disease after spillover transmission to humans and agriculturally important domestic animals that are incidental or dead-end hosts. viruses such as dengue (denv) and chikungunya (chikv) that have lost the requirement for enzootic amplification now produce extensive epidemics in tropical urban centers. many arboviruses recently have increased i ...201019857523
chikungunya virus-vector interactions.chikungunya virus (chikv) is a mosquito-borne alphavirus that causes chikungunya fever, a severe, debilitating disease that often produces chronic arthralgia. since 2004, chikv has emerged in africa, indian ocean islands, asia, europe, and the americas, causing millions of human infections. central to understanding chikv emergence is knowledge of the natural ecology of transmission and vector infection dynamics. this review presents current understanding of chikv infection dynamics in mosquito v ...201425421891
comparison of genotypes i and iii in japanese encephalitis virus reveals distinct differences in their genetic and host diversity.japanese encephalitis (je) is an arthropod-borne disease associated with the majority of viral encephalitis cases in the asia-pacific region. the causative agent, japanese encephalitis virus (jev), has been phylogenetically divided into five genotypes. recent surveillance data indicate that genotype i (gi) is gradually replacing genotype iii (giii) as the dominant genotype. to investigate the mechanism behind the genotype shift and the potential consequences in terms of vaccine efficacy, human c ...201425056890
zika virus on a spreading spree: what we now know that was unknown in the 1950's.zika virus (zikv) is a mosquito-borne flavivirus that is transmitted through the bite of aedes spp mosquitoes and less predominantly, through sexual intercourse. prior to 2007, zikv was associated with only sporadic human infections with minimal or no clinical manifestations. recently the virus has caused disease outbreaks from the pacific islands, the americas, and off the coast of west africa with approximately 1.62 million people suspected to be infected in more than 60 countries around the g ...201627716242
the mysterious zika virus: adding to the tropical flavivirus mayhem.until now, known as the demure cousin of dengue virus (denv) inhabiting africa, zika virus (zikv) has reinvented itself to cause explosive epidemics captivating the western hemisphere. the outbreak causing potential for zikv was realized when it made its way from africa to yap island micronesia in 2007, and in french polynesia in 2013. from there, it moved on to brazil in 2015. now zikv has infected people in more than 33 countries in central and south america and the caribbean. moreover the epi ...027763483
history, epidemiology, and clinical manifestations of zika: a systematic review.to describe salient epidemiological characteristics of zika virus outbreaks across the world and to examine the clinical presentations, complications, and atypical manifestations related to their occurrence in recent history.026959260
the wmel strain of wolbachia reduces transmission of zika virus by aedes aegypti.zika virus (zikv) is causing an explosive outbreak of febrile disease in the americas. there are no effective antiviral therapies or licensed vaccines for this virus, and mosquito control strategies have not been adequate to contain the virus. a promising candidate for arbovirus control and prevention relies on the introduction of the intracellular bacterium wolbachia into aedes aegypti mosquitoes. this primarily has been proposed as a tool to control dengue virus (denv) transmission; however, e ...201627364935
zika virus in gabon (central africa)--2007: a new threat from aedes albopictus?chikungunya and dengue viruses emerged in gabon in 2007, with large outbreaks primarily affecting the capital libreville and several northern towns. both viruses subsequently spread to the south-east of the country, with new outbreaks occurring in 2010. the mosquito species aedes albopictus, that was known as a secondary vector for both viruses, recently invaded the country and was the primary vector involved in the gabonese outbreaks. we conducted a retrospective study of human sera and mosquit ...201424516683
distribution of mosquito larvae on kosrae island, kosrae state, the federated states of micronesia.surveys of mosquito larvae were carried out in six areas of kosrae island, kosrae state, the federated states of micronesia in december 2009 and june 2012. a total of 962 larvae of six species were collected from 106 natural and artificial habitats. they were identified as aedes aegypti, ae. albopictus, ae. marshallensis, culex quinquefasciatus, cx. annulirostris, and cx. kusaiensis. this is the first report from kosrae island for three of these species-ae. marshallensis, cx. quinquefasciatus, a ...201324478593
zika mosquito vectors: the jury is still out.after a 40-year hiatus, the international congress of entomology (ice 2016) convened in orlando, florida (september 25-30, 2016). one of the symposia at ice 2016, the zika symposium, covered multiple aspects of the zika epidemic, including epidemiology, sexual transmission, genetic tools for reducing transmission, and particularly vector competence. while there was a consensus among participants that the yellow fever mosquito, aedes aegypti, is a vector of the zika virus, there is growing eviden ...201627853521
aedes hensilli as a potential vector of chikungunya and zika viruses.an epidemic of zika virus (zikv) illness that occurred in july 2007 on yap island in the federated states of micronesia prompted entomological studies to identify both the primary vector(s) involved in transmission and the ecological parameters contributing to the outbreak. larval and pupal surveys were performed to identify the major containers serving as oviposition habitat for the likely vector(s). adult mosquitoes were also collected by backpack aspiration, light trap, and gravid traps at se ...201425299181
characterization of lethal zika virus infection in ag129 mice.mosquito-borne zika virus (zikv) typically causes a mild and self-limiting illness known as zika fever, which often is accompanied by maculopapular rash, headache, and myalgia. during the current outbreak in south america, zikv infection during pregnancy has been hypothesized to cause microcephaly and other diseases. the detection of zikv in fetal brain tissue supports this hypothesis. because human infections with zikv historically have remained sporadic and, until recently, have been limited t ...201627093158
distribution of aedes albopictus (diptera, culicidae) in southwestern pacific countries, with a first report from the kingdom of tonga.aedes (stegomyia) albopictus is currently one of the most notorious globally invasive mosquito species. its medical importance is well documented, and its fast expansion throughout most continents is being monitored with concern. it is generally assumed that its expansion through the western pacific island countries has not progressed since its establishment in fiji in 1989. however, the current status of ae. albopictus in the pacific region is largely unknown.201223130961
global risk model for vector-borne transmission of zika virus reveals the role of el niño 2015.zika, a mosquito-borne viral disease that emerged in south america in 2015, was declared a public health emergency of international concern by the who in february of 2016. we developed a climate-driven r0 mathematical model for the transmission risk of zika virus (zikv) that explicitly includes two key mosquito vector species: aedes aegypti and aedes albopictus the model was parameterized and calibrated using the most up to date information from the available literature. it was then driven by ob ...201627994145
variation in cold hardiness of nondiapausing eggs of nine aedes (stegomyia) species (diptera: culicidae) from eastern asia and pacific islands ranging from the tropics to the cool-temperate zone.variation in cold hardiness was studied in the laboratory for the nondiapausing eggs of nine aedes (stegomyia) species from eastern asia and pacific islands, ranging from the tropics to the cool-temperate zone. species included were aedes aegypti (l.), aedes albopictus (skuse), aedes flavopictus yamada, aedes galloisi yamada, aedes hensilli farner, aedes palauensis bohart, aedes paullusi stone and farner, aedes riversi bohart and ingram, and aedes scutellaris (walker). for species with distribut ...201121485356
epidemic of dengue-4 virus in yap state, federated states of micronesia, and implication of aedes hensilli as an epidemic vector.a dengue fever/dengue hemorrhagic fever (df/dhf) outbreak in yap state caused by dengue-4 virus was confirmed serologically and by virus isolation from serum samples collected on each of three island groups. most df/dhf cases occurred during a three-month period between mid-may and early august 1995. five fatal cases, three of which were in children between the ages of four and 11, occurred between june 20 and july 26. a serosurvey conducted in late august revealed anti-dengue igm prevalence rat ...19989574802
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