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the expanding lyme borrelia complex--clinical significance of genomic species?ten years after the discovery of spirochaetes as agents of lyme disease in 1982 in the usa, three genomic species had diverged from the phenotypically heterogeneous strains of borrelia burgdorferi isolated in north america and europe: borrelia afzelii, b. burgdorferi sensu stricto (further b. burgdorferi), and borrelia garinii. whereas b. burgdorferi remained the only human pathogen in north america, all three species are aetiological agents of lyme borreliosis in europe. another seven genospeci ...201121414082
borrelia burgdorferi sensu lato in ixodes longiscutatus ticks from brazilian pampa.borrelia burgdorferi sensu lato (s.l.) complex includes the agents of lyme disease/borreliosis in north america, europe, and asia, such borrelia burgdorferi sensu stricto, borrelia afzelii, borrelia garinii, borrelia bavariensis, borrelia spielmanii, borrelia bissettiae, and borrelia mayonii. in 2013 b. burgdorferi s.l. was reported for the first time in the neotropical region, from ixodes aragaoi ticks in uruguayan pampa. in addition, from 2011 to 2016, 17 suspected human cases of borreliosis-l ...201728847698
borrelia bissettiae sp. nov. and borrelia californiensis sp. nov. prevail in diverse enzootic transmission cycles.two borrelia species, borrelia bissettiae sp. nov. and borrelia californiensis sp. nov., were first described by postic and co-workers (postic et al., 2007; postic et al., 1998) based on genetic analyses of several loci. multilocus sequence analysis (mlsa) of eight housekeeping loci confirmed that these two borrelia genospecies are distinct members of the b. burgdorferi s. l. complex (margos et al., 2010). b. bissettiae sp. nov. initially was described in transmission cycles involving neotoma fu ...201626813420
multilocus sequence analysis of atypical borrelia burgdorferi sensu lato isolates--description of borrelia californiensis sp. nov., and genomospecies 1 and 2.taxonomy of borrelia burgdorferi sensu lato (s.l.) was recently improved by the use of multilocus sequence analysis (mlsa), a new approach to replace the cumbersome dna-dna hybridization method [richter et al., 2006. int. j. syst. evol. microbiol. 156, 873-881]. in this study, we used this methodology to classify b. burgdorferi s.l. strains isolated both in europe and the united states, the exact taxonomic status of which remained unclear. we conclude that mlsa can surpass the discrimination pow ...200717374507
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