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expanding the definition of class 3 inteins and their proposed phage origin.inteins are the protein equivalent of introns. their protein splicing activity is essential for the host protein's maturation and function. inteins are grouped into three classes based on sequence signature and splicing mechanism. the sequence signature of the recently characterized class 3 inteins is a noncontiguous trp-cys-thr (wct) motif and the absence of the standard class 1 cys¹ or ser¹ n-terminal nucleophile. the intein n-terminal cys¹ or ser¹ residue is essential for splicing in class 1 ...201121317331
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