Publications

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chromosome banding pattern relationships of hares, rabbits, and pikas (order lagomorpha). a phyletic interpretation.the chromosome banding patterns of the domestic rabbit, oryctolagus cuniculus, the brush rabbit, sylvilagus bachmani, and the snowshoe hare, lepus americanus, are nearly identical except for minor differences in the amount of constitutive heterochromatin present. the major mechanisms of chromosome evolution in leporid lagomorphs are centric fusion and addition of heterochromatin. the g- and c-banding patterns of the pika, ochotona princeps, revealed little easily recognized structural homology w ...1976975938
lagomorphs as sentinels for surveillance of borreliosis in the far western united states.brush rabbits (sylvilagus bachmani) and black-tailed jackrabbits (lepus californicus) from california (usa) were assayed for antibodies to borrelia burgdorferi, the etiologic agent of lyme borreliosis. significant antibody titers were detected in 90% (range, 67 to 100%) of brush rabbits from four of six localities, and in 90% of jackrabbits from a single locality, in northern california. one of the populations of brush rabbits that did not yield seropositive individuals inhabited an oceanic isla ...19892716099
organ weights and sexual dimorphism of the brush rabbit. 19715581379
role of small mammals in the ecology of borrelia burgdorferi in a peri-urban park in north coastal california.the role of small mammals other than woodrats in the enzootiology of the lyme disease spirochete, borrelia burgorferi, was assessed in the peri-urban park. mammals were collected monthly from september through to april. following tick removal, the animals were tested for b. burgdorferi by culture of ear-punch biopsies. larvae and nymphs that were intermediate in morphology between ixodes spinipalpis and ixodes neotomae occurred on several species of rodents (peromyscus truei, peromyscus californ ...19979291589
studies in the epidemiology of myxomatosis in california. ii. the experimental transmission of myxomatosis in brush rabbits (sylvilagus bachmani) by several species of mosquitoes. 196313950625
prevalence of vector-borne bacterial pathogens in riparian brush rabbits (sylvilagus bachmani riparius) and their ticks.from june to october 2010, 48 endangered riparian brush rabbits (sylvilagus bachmani riparius) were trapped at a captive propagation site in central california with the intention of release into re-established habitats. during prerelease examinations, ticks and blood samples were collected for surveillance for rickettsia spp., anaplasma phagocytophilum, borrelia burgdorferi, and bartonella spp. ticks were identified, and dna was extracted for pcr analysis. serology was performed to detect exposu ...201424506421
evolutionary insights into il17a in lagomorphs.in leporids, il17a had been implicated in the host defense against extracellular pathogens, such as francisella tularensis that infects hares and rabbits and causes the zoonotic disease tularemia. here, we studied il17a from five lagomorphs, european rabbit, pygmy rabbit, brush rabbit, european brown hare, and american pika. we observed that this protein is highly conserved between these species, with a similarity of 97-99% in leporids and ~88% between leporids and american pika. the exon/intron ...201526788019
hematologic and biochemistry reference values for the endangered riparian brush rabbit (sylvilagus bachmani riparius).the objective of this study was to establish reference hematologic and biochemistry values for adult riparian brush rabbits (sylvilagus bachmani riparius). between february 2002 and december 2003, complete blood cell counts and serum biochemistry panels were done on blood samples collected for 252 healthy, adult riparian brush rabbits that were bred in captivity and released to the wild in the california, usa, san joaquin valley. significant differences in mean values of some analytes were found ...200919395758
myxomatosis in a california brush rabbit (sylyilagus bachmani). 196013767210
first report of myxomatosis in mexico.an outbreak of myxomatosis occurred between september and october 1993 on a rabbit farm in punta colnett (ensenada, baja california in northwestern mexico, transpeninsular highway, km 128) and was confirmed by the mexico-usa commission for prevention of foreign diseases of animals (cpa). this represents the first officially confirmed case of the disease in mexico. like the cases in california (usa), the brush rabbit (sylvilagus bachmani) seems to be the carrier of the virus, since serum samples ...200010941750
an n-acyl glycyltaurine conjugate of deoxycholic acid in the biliary bile acids of the rabbit.jj biliary bile acid composition of the adult and neonatal domestic rabbit, as well as that of the adult brush rabbit, was characterized. in adult domestic rabbits, the dominant bile acid present was deoxycholic acid (88% of total bile acids), a secondary bile acid formed by the bacterial 7-dehydroxylation of cholic acid. although most of the bile acids present were conjugated with glycine, two exceptions were observed. about 3% of deoxycholic acid was conjugated, in n-acyl linkage, with glycyl- ...19989799797
survey for evidence of colorado tick fever virus outside of the known endemic area in california.a virus very similar or identical to colorado tick fever (ctf) virus was recovered from the blood clot of one of 104 black-tailed jack rabbits (lepus californicus) examined during a survey for various zoonotic agents in mammals and ticks from the university of california, hopland field station, mendocino county, california, 1974--79. this is the first reported isolation of a ctf-like virus from l. californicus, and only the second time such a virus has been found in northwestern california. mend ...19827102919
a myxoma virus epizootic in a brush rabbit population. 19724634525
a survey for toxoplasma gondii antibodies in deer and other wildlife on a sheep range.blood samples were obtained from native mammals and birds on a sheep range (hopland field station) in northern california. serums were tested for antibodies to toxoplasma gondii by the indirect hemagglutination test. of 382 deer that were tested from 1964 to 1973, 77 (20%) were seropositive for t gondii. among 36 serums representing 6 species of wild carnivores (badgers, bobcats, coyotes, foxes, raccoons, and skunks), 18 (50%) were seropositive. all of the 5 bobcats tested were seropositive, wit ...19751176348
outbreak of rabbit hemorrhagic disease virus 2 in the southwestern united states: first detections in southern california.an outbreak of rabbit hemorrhagic disease virus 2 (rhdv2)-associated disease occurred in the southwestern united states following its first detection in new mexico in march 2020. the disease spread throughout several states and was diagnosed for the first time in california on may 11, 2020, in a black-tailed jackrabbit (lepus californicus). the following day, the california department of food and agriculture (cdfa) issued an order banning the entrance into california of several lagomorph species ...202133797311
a molecular survey for francisella tularensis and rickettsia spp. in haemaphysalis leporispalustris (acari: ixodidae) in northern california.francisella tularensis and rickettsia spp. have been cultured from haemaphysalis leporispalustris packard, but their prevalence in this tick has not been determined using modern molecular methods. we collected h. leporispalustris by flagging vegetation and leaf litter and from lagomorphs (lepus californicus gray and sylvilagus bachmani (waterhouse)) in northern california. francisella tularensis dna was not detected in any of 1,030 ticks tested by polymerase chain reaction (pcr), whereas 0.4% of ...201628031350
genetic evidence supports <i>sylvilagus mansuetus</i> (lagomorpha: leporidae) as a subspecies of <i>s. bachmani</i>.since sylvilagus bachmani (lagomorpha: leporidae) from the baja california peninsula and s. mansuetus from san jose island, mexico, display an allopatric distribution and are closely related, their taxonomy is unclear. the phylogenetic relationships among specimens of both species were evaluated using two mitochondrial genes (cyt b, coi) and the beta-fibrinogen nuclear gene intron 7 (β-fib i7). the genetic analyses revealed that s. mansuetus was included within the s. bachmani clade as the siste ...201627988677
convergent evolution of il-6 in two leporids (oryctolagus and pentalagus) originated an extended protein.interleukin 6 (il-6) is a class-i helical cytokine with a broad spectrum of biological activities and a gene structure conserved throughout vertebrates, with five coding exons. il-6 from european rabbits belonging to the subspecies oryctolagus cuniculus cuniculus was previously shown to differ from other mammals by extending an additional 27 amino acids. however, in other leporids (sylvilagus spp and lepus spp) that diverged from the european rabbit ~12 million years ago this mutation was not pr ...201425027474
limb bone morphology, bone strength, and cursoriality in lagomorphs.the primary aim of this study is to broadly evaluate the relationship between cursoriality (i.e. anatomical and physiological specialization for running) and limb bone morphology in lagomorphs. relative to most previous studies of cursoriality, our focus on a size-restricted, taxonomically narrow group of mammals permits us to evaluate the degree to which 'cursorial specialization' affects locomotor anatomy independently of broader allometric and phylogenetic trends that might obscure such a rel ...201425046350
myxomatosis in australia and europe: a model for emerging infectious diseases.myxoma virus is a poxvirus naturally found in two american leporid (rabbit) species (sylvilagus brasiliensis and sylvilagus bachmani) in which it causes an innocuous localised cutaneous fibroma. however, in european rabbits (oryctolagus cuniculus) the same virus causes the lethal disseminated disease myxomatosis. the introduction of myxoma virus into the european rabbit population in australia in 1950 initiated the best known example of what happens when a novel pathogen jumps into a completely ...201222333483
comparative analysis of the complete genome sequence of the california msw strain of myxoma virus reveals potential host adaptations.myxomatosis is a rapidly lethal disease of european rabbits that is caused by myxoma virus (myxv). the introduction of a south american strain of myxv into the european rabbit population of australia is the classic case of host-pathogen coevolution following cross-species transmission. the most virulent strains of myxv for european rabbits are the californian viruses, found in the pacific states of the united states and the baja peninsula, mexico. the natural host of californian myxv is the brus ...201323986601
evolution of viral sensing rig-i-like receptor genes in leporidae genera oryctolagus, sylvilagus, and lepus.one of the most severe european rabbit (oryctolagus cuniculus) pathogens is myxoma virus (myxv), a rabbit-specific leporipoxvirus that causes the highly lethal disease myxomatosis. other leporid genera, sylvilagus and lepus, encompass species with variable susceptibilities to myxv, but these do not develop the lethal form of the disease. the protective role of the retinoic acid-inducible gene-i (rig-i/ddx58) in sensing myxv in nonpermissive human myeloid cells prompted the study of the rig-i-lik ...201424220721
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