| prevotella copri sp. nov. and prevotella stercorea sp. nov., isolated from human faeces. | six strains (cb7(t), cb18, cb23, cb26, cb28 and cb35(t)) were isolated from human faeces. based on phylogenetic analysis, phenotypic characteristics, cellular fatty acid profiles and menaquinone profiles, these strains could be included within the genus prevotella and made up two clusters. 16s rrna gene sequence analysis indicated that five strains were most closely related to prevotella veroralis, sharing about 92 % sequence similarity; the remaining strain was most closely related to prevotell ... | 2007 | 17473237 |
| comparison of human gut microbiota in control subjects and patients with colorectal carcinoma in adenoma: terminal restriction fragment length polymorphism and next-generation sequencing analyses. | colorectal cancer (crc) is the third leading cause of cancer-related deaths in japan. the etiology of crc has been linked to numerous factors including genetic mutation, diet, life style, inflammation, and recently, the gut microbiota. however, crc-associated gut microbiota is still largely unexamined. this study used terminal restriction fragment length polymorphism (t-rflp) and next-generation sequencing (ngs) to analyze and compare gut microbiota of japanese control subjects and japanese pati ... | 2016 | 26549775 |
| gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic t-cell activation in untreated hiv-1 infection. | hiv-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. dendritic cells (dcs) are crucial in maintaining intestinal homeostasis, but the impact of hiv-1 infection on intestinal dc number and function has not been extensively studied. we compared the frequency and activation/maturation status of colonic myeloid dc (mdc) subsets (cd1c(+) and cd1c(neg)) and plasmacytoid dcs in untreated hiv-1-infected subjects with uninfect ... | 2016 | 25921339 |
| the transcriptome of hiv-1 infected intestinal cd4+ t cells exposed to enteric bacteria. | global transcriptome studies can help pinpoint key cellular pathways exploited by viruses to replicate and cause pathogenesis. previous data showed that laboratory-adapted hiv-1 triggers significant gene expression changes in cd4+ t cell lines and mitogen-activated cd4+ t cells from peripheral blood. however, hiv-1 primarily targets mucosal compartments during acute infection in vivo. moreover, early hiv-1 infection causes extensive depletion of cd4+ t cells in the gastrointestinal tract that he ... | 2017 | 28241075 |
| the impact of the bovine fecal microbiome on escherichia coli o157:h7 prevalence and enumeration in naturally infected cattle. | the objective of this study was to determine if the fecal microbiome has an association with e. coli o157:h7 prevalence and enumeration. | 2017 | 28736954 |
| dietary gluten-induced gut dysbiosis is accompanied by selective upregulation of micrornas with intestinal tight junction and bacteria-binding motifs in rhesus macaque model of celiac disease. | the composition of the gut microbiome reflects the overall health status of the host. in this study, stool samples representing the gut microbiomes from 6 gluten-sensitive (gs) captive juvenile rhesus macaques were compared with those from 6 healthy, age- and diet-matched peers. a total of 48 samples representing both groups were studied using v4 16s rrna gene dna analysis. samples from gs macaques were further characterized based on type of diet administered: conventional monkey chow, i.e., whe ... | 2016 | 27801835 |