Publications

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peruvian horse sickness virus and yunnan orbivirus, isolated from vertebrates and mosquitoes in peru and australia.during 1997, two new viruses were isolated from outbreaks of disease that occurred in horses, donkeys, cattle and sheep in peru. genome characterization showed that the virus isolated from horses (with neurological disorders, 78% fatality) belongs to a new species the peruvian horse sickness virus (phsv), within the genus orbivirus, family reoviridae. this represents the first isolation of phsv, which was subsequently also isolated during 1999, from diseased horses in the northern territory of a ...200919766284
enhanced arbovirus surveillance with deep sequencing: identification of novel rhabdoviruses and bunyaviruses in australian mosquitoes.viral metagenomics characterizes known and identifies unknown viruses based on sequence similarities to any previously sequenced viral genomes. a metagenomics approach was used to identify virus sequences in australian mosquitoes causing cytopathic effects in inoculated mammalian cell cultures. sequence comparisons revealed strains of liao ning virus (reovirus, seadornavirus), previously detected only in china, livestock-infecting stretch lagoon virus (reovirus, orbivirus), two novel dimarhabdov ...201324314645
zoonotic and emerging orbivirus infections.many novel emerging orbiviruses have been isolated in the past 15 years. important viruses include peruvian horse sickness virus (phsv) and yunnan orbivirus (yuov), pathogens of equids which were originally isolated almost simultaneously from 1997 to 1999 in the people's republic of china, australia and peru. yuov has also been isolated from cattle, sheep and a dog. the isolation of yuovfrom a dog is not the first case of an orbivirus being isolated from a carnivore. bluetongue virus and african ...201526601440
association of vectors and environmental conditions during the emergence of peruvian horse sickness orbivirus and yunnan orbivirus in northern peru.since 1983, cases of diseased donkeys and horses with symptoms similar to those produced by alphaviruses were identified in two departments in northern peru; however serological testing ruled out the presence of those viruses and attempts to isolate an agent were also unproductive. in 1997, also in northern peru, two new orbiviruses were discovered, each recognized as a causative agent of neurological diseases in livestock and domestic animals and, at the same time, mosquitoes were found to be i ...201526611971
re-emergence of bluetongue, african horse sickness, and other orbivirus diseases.arthropod-transmitted viruses (arboviruses) are important causes of disease in humans and animals, and it is proposed that climate change will increase the distribution and severity of arboviral diseases. orbiviruses are the cause of important and apparently emerging arboviral diseases of livestock, including bluetongue virus (btv), african horse sickness virus (ahsv), equine encephalosis virus (eev), and epizootic hemorrhagic disease virus (ehdv) that are all transmitted by haematophagous culic ...201020167199
confirmation of elsey virus infection in a queensland horse with mild neurologic signs.in 2011, a 2-year-old horse in northern queensland, australia, was reported to have developed mild neurologic signs, and a blood sample was submitted for laboratory investigation. virus isolation was performed using the blood sample, and an orbivirus was isolated. this was confirmed to be a strain of elsey virus (elsv) after transmission electron microscopy and nucleotide sequencing. the nucleotide sequence was compared with those in genbank, and had 100% identity with elsv previously reported f ...201627240568
mobuck virus genome sequence and phylogenetic analysis: identification of a novel orbivirus isolated from a white-tailed deer in missouri, usa.the genus orbivirus includes a diverse group of segmented dsrna viruses that are transmitted via arthropods, have a global distribution and affect a wide range of hosts. a novel orbivirus was co-isolated with epizootic haemorrhagic disease virus (ehdv) from a white-tailed deer (odocoileus virginianus) exhibiting clinical signs characteristic of ehdv. using antiserum generated against ehdv, a pure isolate of the novel non-cytopathic orbivirus was obtained in aedes albopictus cell culture. genomic ...201424114792
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