Publications

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distribution of sequence differences in influenza n9 neuraminidase of tern and whale viruses and crystallization of the whale neuraminidase complexed with antibodies.neuraminidase genes from a/tern/australia/g70c/75 (h11n9) and a/whale/maine/1/84 (h13n9) influenza viruses have been sequenced. seventy-two nucleotide changes were found, 17 of which result in changes in the amino acid sequence of the neuraminidase; 3 in the stalk region and 14 in the heads. to our surprise, all of the sequence changes in the head region are located on the base of the neuraminidase tetramer, resulting in conservation of antigenic sites on top of the neuraminidase which vary exte ...19873660585
avian influenza virus isolated in wild waterfowl in argentina: evidence of a potentially unique phylogenetic lineage in south america.avian influenza (ai) viruses have been sporadically isolated in south america. the most recent reports are from an outbreak in commercial poultry in chile in 2002 and its putative ancestor from a wild bird in bolivia in 2001. extensive surveillance in wild birds was carried out in argentina during 2006-2007. using rrt-pcr, 12 ai positive detections were made from cloacal swabs. one of those positive samples yielded an ai virus isolated from a wild kelp gull (larus dominicanus) captured in the so ...200818632129
influenza a viruses in american white pelican (pelecanus erythrorhynchos).the role of many wild waterbird species in the ecology and epidemiology of avian influenza viruses (aiv) remains unclear. we report the first isolation of aiv from american white pelicans (pelecanus erythrorhynchos; pelecaniformes) in north america. two h13n9 aivs were isolated from hatchling birds in breeding colonies in minnesota, usa, during 2007 and 2008. based on molecular sequencing of the hemagglutinin and neuraminidase genes, the 2008 virus was genetically related to aivs previously isol ...201020966281
avian influenza in wild birds from chile, 2007-2009.aquatic and migratory birds, the main reservoir hosts of avian influenza viruses including those with high pathogenic potential, are the wildlife species with the highest risk for viral dissemination across countries and continents. in 2002, the chilean poultry industry was affected with a highly pathogenic avian influenza strain, which created economic loss and triggered the establishment of a surveillance program in wild birds. this effort consisted of periodic samplings of sick or suspicious ...201525602438
novel multiplex assay platforms to detect influenza a hemagglutinin subtype-specific antibody responses for high-throughput and in-field applications.detections of influenza a subtype-specific antibody responses are often complicated by the presence of cross-reactive antibodies. we developed two novel multiplex platforms for antibody detection. the multiplexed magnetic fluorescence microsphere immunoassay (magpix) is a high-throughput laboratory-based assay. chembio dual path platform (dpp) is a portable and rapid test that could be used in the field.201728207986
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