| proteomic analysis of skin defensive factors of tree frog hyla simplex. | tree frogs produce a variety of skin defensive chemicals against many biotic and abiotic risk factors for their everyday survival. by proteomics or peptidomics and coupling transcriptome analysis with pharmacological testings, 27 peptides or proteins belonging to 9 families, which act mainly as defensive functions, were identified and characterized from skin secretions of the tree frog, hyla simplex. they are: (1) a novel family of peptides with egf- and vegf-releasing activities; (2) a novel fa ... | 2011 | 21740067 |