| sensitivity of group c arboviruses (bunyaviridae) to human amnion interferon. | the sensitivity of several group c arboviruses (bunyaviridae) to human amnion interferon was compared to that of vesicular stomatitis virus (vsv) and sindbis virus. in cpe inhibition assays. apeu virus was the most sensitive of the group c arboviruses tested; it was significantly more inhibited than vsv, but was in the same range as sindbis virus. in plaque reduction assays, the increasing order of sensitivity was apeu, marituba, vsv and sindbis viruses. single-cycle yields of vsv and apeu virus ... | 1980 | 6162822 |
| a case of apeu virus infection. | | 1964 | 14106040 |
| [experimental infection using apeu virus in mice (mus musculus albinus). histopathological injuries]. | | 1969 | 4981020 |
| evidence of apeu virus infection in wild monkeys, brazilian amazon. | orthobunyaviruses are arboviruses in which at least 30 members are human pathogens. the members of group c orthobunyaviruses were first isolated in the brazilian amazon in 1950, since that time little information is accumulated about ecology and the medical impact of these virus groups in brazil. herein, we describe the evidence of apeu virus (apeuv; an orthobunyavirus member) infection in wild monkeys from the brazilian amazon forest. apeuv was detected by using a neutralizing antibody in serum ... | 2016 | 26787153 |
| identification of a phylogenetically distinct orthobunyavirus from group c. | apeu virus (apeuv) (family bunyaviridae, genus orthobunyavirus) was plaque purified and characterised by serological and molecular analysis. neutralising assays confirmed cross-reactivity between purified apeuv clones and the caraparu virus complex of group c orthobunyaviruses. partial sequencing of the l, m and s segments of one apeuv clone (apeuv-cl5) was carried out. a phylogenetic tree constructed with the l amino acid sequences clustered apeuv-cl5 within the genus orthobunyavirus, confirmin ... | 2011 | 21465087 |
| antiviral activity of type i interferons and interleukins 29 and 28a (type iii interferons) against apeu virus. | interferons (ifns) are cytokines with important immunomodulatory activity in vertebrates. although type i ifns and interleukins (il) 29 and 28a (type iii ifns) bind to different cellular receptors and have distinct structures, most of their biological activities are redundant. apeu virus (apeuv) is a member of the bunyaviridae family isolated from the brazilian rain forest. in this paper we evaluated the antiviral activity of type i and type iii ifns against apeuv. all tested ifns were able to i ... | 2008 | 18657576 |