| a precipitin test for the diagnosis of human abdominal angiostrongyliasis. | a precipitin reaction was observed when sera of cotton rats infected either naturally or experimentally with angiostrongylus costaricensis were tested by gel double-diffusion against sera obtained from three biopsy-confirmed human cases of a. costaricensis. with immunoelectrophoresis, the antigen was demonstrated in the serum of infected rats. the antibody in the human serum was mostly of the igg type. no cross reactions were seen with sera from individuals infected with the common intestinal he ... | 1977 | 413446 |
| [infection of wild rats with angiostrongylus costaricensis by intraperitoneal subcutaneous route]. | three groups of cotton rats (sigmodon hispidus) were infected with angiostrongylus costaricensis; the first was inoculated by stomach tube; the second intraperitoneally and the third subcutaneously. in all the groups each rat received 50 l3. the highest rates of infection (51.5%) were obtained by the intraperitoneal route, followed by oral inoculation (47.1%). poor results were observed (10.5%) subcutaneously. | 1977 | 615323 |
| viability of the first stage larvae of angiostrongylus costaricensis in rat feces. | | 1978 | 627956 |
| angiostrongylus costaricensis in panama. prevalence and pathologic findings in wild rodents infected with the parasite. | | 1973 | 4706428 |
| [studies of the definitive host of angiostrongylus costaricensis. (morera and céspedes, 1971)]. | | 1970 | 5518359 |
| [studies on the intermediate host of angiostrongylus costaricensis (morera and céspedes, 1971)]. | | 1970 | 5518360 |
| angiostrongylus costaricensis n. sp. (nematoda: metastrongyloidea), a new lungworm occurring in man in costa rica. | | 1970 | 5527668 |
| spermatic artery obstruction caused by angiostrongylus costaricensis morera and céspedes, 1971. | an 8-year-old boy was admitted to hospital with acute testicular pain. a diagnosis of torsion of the testicle was made, and an orchidectomy was performed. histopathological study showed necrosis of the testicular parenchyma caused by arterial obstruction, and adults of angiostrongylus costaricensis were found within the spermatic arteries. in addition, heavy eosinophilic inflammatory reactions and unfertilized eggs were observed in the excised tissues. | 1983 | 6650745 |
| first record of angiostrongylus costaricensis morera and céspedes, 1971 in ecuador. | third-stage metastrongyle larvae were recovered from slugs (vaginulus sp.) collected in santa lucia, ecuador, a town about 40 miles north of guayaquil. some of the larvae were inoculated into laboratory-bred cotton rats and adults of angiostrongylus costaricensis were later recovered. this is the first report of this parasite in ecuador. | 1983 | 6650746 |
| life history and redescription of angiostrongylus costaricensis morera and céspedes, 1971. | | 1973 | 4729741 |
| pathophysiologic alterations in biomphalaria glabrata infected with angiostrongylus costaricensis. | | 1985 | 3981029 |
| abdominal angiostrongylosis in an african man: case study. | a nodule removed from the cecum of a 25-year-old zairian man contained a degenerated adult nematode. the surrounding tissue contained larvae and eggs in various stages of cleavage. eggs and larvae were indistinguishable from those of angiostrongylus costaricensis. these morphological features are described. the diameter and cuticle, and the anatomic location of the adult worm is consistent with a. costaricensis. the tissue reaction was chronic with granulomatous inflammation and numerous eosinop ... | 1987 | 3661828 |
| angiostrongylus costaricensis in a black-eared marmoset. | a case of angiostrongylus costaricensis in a captive c. penicillata in a german zoological garden is described. clinical symptoms were lacking, the morphological lesions consisted of intestinal granulomas harbouring rhabdidiform larvae. the adult worms were present in the ileo-caecal branches of the mesenteric artery. | 1995 | 7483006 |
| [intestinal angiostrongyliasis caused by angiostrongylus costaricencis. apropos of a case in martinique]. | intestinal angiostrongyliasis caused by angiostrongylus costaricensis is a rare nematodiasis which is present mainly in costa-rica, and in some other countries in the northern part of south america, central america, and in the southern part of mexico. this is a report of the first case from martinique involving a sixteen month old child, and proved by an intestinal pathologic study. the epidemiology of the disease, its clinical, parasitological, histopathologic and therapeutic aspects are emphas ... | 1988 | 3384256 |
| the intermediate host of angiostrongylus costaricensis in honduras. | | 1988 | 3273607 |
| [influence of the age of veronicellid slugs in angiostrongylus costaricensis infection]. | in costa rica, veronicellid slugs are the most important intermediate hosts for angiostrongylus costaricensis. apparently, these molluscs develop a resistant mechanism after being exposed to the infection. in naturally infected slugs, the higher infection rates were found in large slugs, but they usually bear few larvae. large number of larvae were found in medium sized molluscs. experimental infection in laboratory breed slugs produced an amebocytic reaction around developing larvae; later, the ... | 1988 | 3273604 |
| angiostrongyliasis: a rare cause of gastrointestinal hemorrhage. | angiostrongylus costaricensis is an intestinal nematode, endemic to central and south america. affecting mostly children, it causes an eosinophilic gastroenteritis with involvement of the appendix, distal small bowel, and right colon. we report a case of a 41-yr-old man, from a non-endemic area, with the unique presentation of recurrent gastrointestinal bleeding. the diagnosis was made after surgical exploration. | 1989 | 2784029 |
| strain-dependent differences in susceptibility of mice to experimental angiostrongylus costaricensis infection. | experimental angiostrongylus costaricensis infection was carried out in inbred strains of mice (c57bl/6 balb/c, dba/2 and c3h/he). all strains became infected with this parasite. marked differences in mortality and in worm burden were found among inbred strains of mice tested. a significant reduction was shown in worm length from mice compared to that from cotton rats. | 1989 | 2532233 |
| phyllocaulis variegatus--an intermediate host of angiostrongylus costaricensis in south brazil. | molluscs collected in five localities in the state of rio grande do sul (brazil) were digested and examined. the infected slugs were identified as phyllocaulis variegatus and the larvae found were inoculated per os into mice. after 50 days, worms with the caracteristics of angiostrongylus costaricensis were recovered from the mesenteric arterial system. the results establish the role of p. variegatus as intermediate host of a. costaricensis in south brazil, where many cases of abdominal angiostr ... | 1989 | 2319952 |
| [identification of wild rodents as hosts of angiostrongylus costaricencis in southern brazil]. | increasing number of human cases of abdominal angiostrongyliasis has been diagnosed in the south of brazil. the main definitive host of angiostrongylus costaricensis in central america is the cotton rat (sigmodon hispidus) that does not occur in south america, except in the north of colombia, peru and venezuela. rodents were captured in the endemic area in rio grande do sul (rs) and definitive hosts were identified for the first time in brazil: oryzomys nigripes and oryzomys ratticeps. o. nigrip ... | 1990 | 2135366 |
| effects of sensitization on efficacy of mebendazole in mice infected with adult angiostrongylus costaricensis. | the relation between immunopotentiation and efficacy of mebendazole in sensitized mice infected with adult angiostrongylus costaricensis was investigated. when compared with the non-treated control, the sensitized control showed better results in almost all parameters with a few mice being positive for the first-stage larvae in feces and eggs in the intestinal section. the results suggest development of protective immunity in the sensitized mice though it was not completely effective for inhibit ... | 1993 | 8134774 |
| scanning electron microscopic observations of first- and third-stage larvae and adults of angiostrongylus costaricensis. | the surfaces of larval and adult angiostrongylus costaricensis, causative agent of human abdominal granuloma, were studied by the use of scanning electron microscopy. cuticular annulations were clearly demonstrated on the surface of larvae and adults. differences in the appearance of alae in larval stages and in the shape of the tail at different stages of development are described and illustrated. several aspects of morphology previously unreported for this parasite are also described. | 1990 | 2098918 |
| angiostrongylus costaricensis: culture of third-stage larvae to young adults in a defined medium. | the third-stage larvae of angiostrongylus costaricensis were successfully cultured to young adults in a chemically defined medium. the most suitable medium for the development was waymouth's medium among eight defined media examined. twenty-eight days after cultivation in this medium, 77% of the larvae developed to young adults, although these worms gradually died thereafter. when waymouth's medium was supplemented with mouse red blood cells, these young adult worms continued their development. ... | 1991 | 1915749 |
| [intestinal perforation by angiostrongylus costaricensis. a report of 2 cases]. | two cases of abdominal angiostronylosis with terminal ileum perforation are reported. the first two cases diagnosed in panama of a well established eosinophilic granulomatous process which affects mostly children in costa rica. the parasite angiostrongylus costaricensis has been demonstrated in cases with a geographic range, from mexico down to brazil. the parasite has been found in rodents in panama (sigmodon hispidus and rattus rattus) with an still pending further epidemiological and serologi ... | 1992 | 1620898 |
| [presence of abdominal angiostrongylosis in guadeloupe. apropos of 2 recent cases]. | the authors describe the first two cases of abdominal angiostrongylosis in guadeloupe, confirmed by a histological analysis. physicians must be aware of the presence of angiostrongylus costaricensis in the west indies in order to provide better care for children presenting with fever, abdominal pain and rectorragiae, along with intense biological markers of inflammation. | 1992 | 1596956 |
| abdominal angiostrongyliasis mimicking acute appendicitis and meckel's diverticulum: report of a case in the united states and review. | two cases of children with abdominal angiostrongyliasis acquired within the united states are reported. the index patient presented with complaints consistent with appendicitis, but at surgery findings were thought to represent an atypical presentation of a meckel's diverticulum. his sole sibling (sister) had eosinophilia, no other intestinal parasites on fecal examination, and a positive serologic test, all suggesting infection with angiostrongylus costaricensis. because infections with this pa ... | 1992 | 1576277 |
| [the susceptibility of planorbidae from the metropolitan area of belo horizonte, mg (brazil) to angiostrongylus costaricensis (nematoda, angiostrongylidae)]. | biomphalaria glabrata (control), b. tenagophila and b. straminea from our laboratory colonies iniciated with molluscs collected in the municipality of belo horizonte, mg (brasil), were experimentally infected with first-stage larvae of angiostrongylus costaricensis. the number of molluscs of each species exposed was 139, 77 and 149. about 25 days later, surviving molluscs were individually examined by artificial digestion. of 87 b. glabrata examined, 62 (71.3%) were positive and between one and ... | 1992 | 1342102 |
| [sarasinula marginata (semper, 1885) (mollusca, soleolifera) from belo horizonte (mg, brasil) as a potential intermediate host of angiostrongylus costaricensis morera, cespedes, 1971]. | specimens of sarasinula marginata were collected in kitchen and house gardens of belo horizonte, minas gerais. the susceptibility of these molluscs for angiostrongylus costaricensis was tested by infecting 15 laboratory--reared slugs (f1). the positivity demonstrated was of 80.0%. | 1992 | 1340024 |
| angiostrongylus costaricensis natural infection in vaginulus plebeius in nicaragua. | a study of 94 slugs, collected from urban and rural areas in and around léon, nicaragua, was carried out in order to confirm the role of vaginulus plebeius as an intermediate host of angiostronglylus costaricensis. third-stage larvae of a. costaricensis were obtained from these molluscs. some of these larvae were then orally inoculated into two laboratory-bred rats sigmodon hispidus and adult worms of a. costaricensis were recovered two months later. the infection rate of these slugs ranged from ... | 1992 | 1290381 |
| a new definitive natural host of angiostrongylus costaricensis (morera and céspedes 1971). | | 1978 | 627972 |
| [appendicitis caused by angiostrongylus costaricensis. presentation of a case]. | | 1979 | 472610 |
| first report of angiostrongylus costaricensis morera and céspedes 1971 in the united states. | | 1979 | 448616 |
| experimental infection of sigmodon hispidus with third-stage larvae of angiostrongylus costaricensis. | adult sigmodon hispidus, were given 50 third-stage larvae of angiostrongylus costaricensis orally, intraperitoneally, subcutaneously, and on abraded and unabraded skin. larvae could not penetrate unbroken skin but established normal infections in the cecal vasculature by all other routes. significantly more adults were recovered after oral and intraperitoneal inoculation than subcutaneously or through abraded skin. in a single animal given larvae subcutaneously, adult worms were recovered from t ... | 1981 | 7241281 |
| presence of angiostrongylus costaricensis morera and céspedes 1971 in colombia. | angiostrongylus costaricensis, producing abdominal angiostrongyliasis, is known to occur in humans and/or rodents in the western hemisphere, namely in the u.s.a. (texas), mexico, honduras, el salvador, costa rica, panama, venezuela, and brazil, rats, oryzomys caliginosus, in colombia were found to harbor the parasite. first-stage larvae from one of these rats developed to third-stage larvae in the slug veronicella occidentalis, also from colombia. | 1981 | 7212175 |
| visceral larva migrans-like syndrome caused by angiostrongylus costaricensis. | in two cases of ectopic localization of angiostrongylus costaricensis adult worms and eggs were seen in the liver, causing a granulomatous inflammatory reaction with dense eosinophilic infiltration and necrosis. in the first case, although antibodies for a. costaricensis had been demonstrated, a clinical diagnosis of visceral larva migrans was recorded; however, further examination of a liver biopsy revealed eggs of a. costaricensis. in the second case, severity of the intestinal pathology maske ... | 1982 | 7058980 |
| spontaneous occurrence of angiostrongylus costaricensis in marmosets (saguinus mystax). | two marmosets imported from iquitos, peru, were found to be infected with angiostrongylus costaricensis. both animals had large solitary granulomas involving the wall and adjacent mesentery of the small intestine. histopathologic examination showed the adult nematodes in the lumina of the mesenteric arteries that coursed through these granulomas. the inflammatory reaction was associated with numerous degenerating eggs and larvae. this is the first report of this parasite in nonhuman primates and ... | 1982 | 6808242 |
| clinical abdominal angiostrongylosis. a study of 116 children with intestinal eosinophilic granuloma caused by angiostrongylus costaricensis. | a total of 116 cases of intestinal eosinophilic granuloma caused by angiostrongylus costaricensis in children were studied during the 10-year period 1966-1975 at costa rica's national children's hospital. a similar prevalence of cases was observed each year. the disease was twice as frequent in males as in females, and occurred predominantly in children 6-13 years old (53% of cases). the clinical symptoms were those of "acute abdomen," with pain at the right iliac fossa, pain on palpation, a tum ... | 1980 | 7406104 |
| emergence of third-stage larvae of angiostrongylus costaricensis morera and cespedes 1971 from biomphalaria glabrata (say). | | 1980 | 7463259 |
| [natural murine infestation by angiostrongylus costaricensis morera and cespedes, 1971 in guadeloupe]. | in 1992, two cases of abdominal angiostrongylosis were reported in young guadeloupean children. with a view to determine the natural infestation rate of guadeloupe rodents (rattus rattus, r. norvegicus) by angiostrongylus costaricensis, 656 rats caught in the country have been examined. both murine species are naturally infested (6.2% in r. rattus and 14.9% in r. norvegicus), which gives a total prevalence of 7.5%. this total prevalence is higher in the tourist area. a complementary investigatio ... | 1993 | 7819811 |
| natural infection of phyllocaulis soleiformis with larvae morphologically similar to l2 of angiostrongylus costaricensis. | | 1994 | 7823811 |
| hepatic lesions induced by angiostrongylus costaricensis. | | 1994 | 7868089 |
| essential amino acids and other essential components for development of angiostrongylus costaricensis from third-stage larvae to young adults. | third-stage larvae of angiostrongylus costaricensis were cultured to the young adult stage in waymouth's chemically defined medium mb 752/1, which contained 18 amino acids, 11 vitamins, glutathione, hypoxanthine, and glucose in a balanced salt solution. nutritional requirements were examined by deletion of single components from waymouth's medium. ten amino acids, namely l-arginine, l-histidine, l-isoleucine, l-leucine, l-lysine, l-methionine, l-phenylalanine, l-threonine, l-tryptophan, and l-va ... | 1994 | 8064517 |
| [human angiostrongyliasis caused by angiostrongylus costaricensis]. | angiostrongylus costaricensis was discovered by morera and céspedes in 1971, in a man suffering from an abdominal syndrome. upon surgery, worms were observed in the cranial mesenteric artery. these worms were assigned to the metastrongylid strongyles and to the genus angiostrongylus, which was already known, in man medicine, by the species a. cantonensis, the causative agent of an eosinophilic meningitis. morera's parasite was named angiostrongylus costaricensis from the place where it was descr ... | 1994 | 8076197 |
| angiostrongylus costaricensis enterocolitis mimics crohn's disease. | | 1993 | 8095521 |
| on the diversity of mollusc intermediate hosts of angiostrongylus costaricensis morera & cespedes, 1971 in southern brazil. | veronicellid slugs are considered the most important intermediate hosts of angiostrongylus costaricensis, an intra-arterial nematode of rodents. studies undertaken in three localities in southern brazil led to identification of molluscs other than veronicellid slugs as hosts of a. costaricensis: limax maximus, limax flavus and bradybaena similaris. these data indicate a low host specificity of larval stages of a. costaricensis, as it has been reported to other congeneric species. | 1993 | 8107609 |
| angiostrongyliasis in a european patient: a rare cause of gangrenous ischemic enterocolitis. | angiostrongylus costaricensis causes a clinicopathologic disease first observed in costa rica, mainly in children characterized by highly symptomatic eosinophilic gastroenteritis involving the terminal ileum, cecum, appendix, and ascending colon. a case of angiostrongyliasis in an adult spaniard infected during a brief stay in nicaragua is reported. we examined the macro-microscopic features of a right ileocolic resection of a 52-year-old patient. in the surgical specimen, multiple confluent ulc ... | 1993 | 8224660 |
| immune defense and eosinophilia in congenitally ige-deficient sja/9 mice infected with angiostrongylus costaricensis. | the roles of ige in protective immunity and eosinophilia in angiostrongylus costaricensis infection were examined by comparing ige-deficient sja/9 mice and ige-producing sjl/j mice. in primary infection, mean total ige levels increased to a maximum of 390 ng/ml, which was more than 10 times greater than the 29 ng/ml measured preinfection in sjl/j mice but less than the 10 ng/ml found in sja/9 mice throughout the experiment. immune defense as determined by recovery of adult worms and eosinophilia ... | 1993 | 8415551 |
| effects of mebendazole on angiostrongylus costaricensis in mice, with special reference to the timing of treatment. | mebendazole was given to mice infected with angiostrongylus costaricensis at a single dose of 5 mg/kg at 6, 11, 16 or 21 days post-infection (p.i.) and in five successive doses at 5 mg/kg daily at 6, 11 or 16 days p.i. the effects were comparatively assessed by examining various parameters in host mice and worms. as a whole, the effects of mebendazole were caused more conspicuously by five successive treatments than by a single treatment. in both treatment modalities, the effects were more remar ... | 1993 | 8415554 |
| unusual infections in humans. | nine cases of unusual infections in humans are presented. in each case, we present the clinical history, histopathologic changes (if indicated), morphologic features of the causative organism, diagnosis, discussion, differential diagnosis, therapy, and current literature. all of the cases are illustrated with pertinent photographs. the nine cases are as follows: (i) acanthocephaliasis, the first acquired human infection by moniliformis moniliformis in the united states; (ii) dipylidiasis, an unc ... | 1993 | 8457979 |
| detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific igg enzyme linked immunosorbent assay. | angiostrongylus costaricensis may cause intestinal lesions of varied severity when it accidentally infects man in central and south america. first-stage larvae have never been detected in stools. therefore, a parasite-specific igg elisa was evaluated for the determination of the acute phase of infection. the specificity and the sensitivity of the immunoassay was shown to be 76.2% and 91.1%, respectively. eight serum samples taken from patients with histopathological diagnosis, at different time ... | 2001 | 11391424 |
| angiostrongylus costaricensis: first record of its occurrence in the state of espirito santo, brazil, and a review of its geographic distribution. | abdominal angiostrongyliasis is a parasitic disease caused by angiostrongylus costaricensis, a metastrongylid nematode with wide geographic distribution, occurring from the united states to argentina. in brazil, the disease has been reported from the states of rio grande do sul, santa catarina, paraná, são paulo, federal district of brasília and minas gerais. we report here a case of abdominal angiostrongyliasis in a 9-year-old girl, from itatiba, state of espirito santo, brazil, submitted to ex ... | 1995 | 8599070 |
| [abdominal angiostrongyliasis: its prevention by the destruction of infecting larvae in food treated with salt, vinegar or sodium hypochlorite]. | there is a high prevalence of accidental human infection with angiostrongylus costaricensis in some areas in southern brazil and sometimes it presents as severe intestinal disease. prophylaxis is important since there is no medical treatment for the disease. the ingestion of fruits and vegetables contaminated with the mucous secretion of infected molluscs (the intermediate hosts) is one of the proposed modes of transmission. third stage larvae were incubated at 5 degrees c for 12 hours, in solut ... | 1995 | 8668840 |
| seroepidemiology of abdominal angiostrongyliasis: the standardization of an immunoenzymatic assay and prevalence of antibodies in two localities in southern brazil. | abdominal angiostrongyliasis is a nematode disease produced by angiostrongylus costaricensis, a metastrongylid parasite of wild rodents. accidental human infection occurs through ingestion of food or water contaminated with third-stage larvae present in the mucous secretion of terrestrial molluscs. an elisa test was standardized for detection of igg antibodies recognizing a surface antigen prepared from female worms. competitive absorption of sera with ascaris suum crude antigen resulted in a te ... | 1997 | 9491104 |
| first reported outbreak of abdominal angiostrongyliasis. | human abdominal angiostrongyliasis is a potentially fatal disease caused by angiostrongylus costaricensis, a nematode found in the americas. during the period of december 1994 through august 1995, an outbreak of this disease occurred in guatemala. we identified 22 cases of abdominal angiostrongyliasis and conducted a matched case-control study to identify risk factors for illness. the median age of the 18 cases enrolled in the study was 37 years (range, 9-68 years), and 11 (61.1%) were male. con ... | 1998 | 9580096 |
| angiostrongylus costaricensis and the intermediate hosts: observations on elimination of l3 in the mucus and inoculation of l1 through the tegument of mollucs. | human accidental infection with angiostrongylus costaricensis may result in abdominal disease of varied severity. slugs from the veronicellidae family are the main intermediate hosts for this parasitic nematode of rodents. phyllocaulis variegatus, phyllocaulis soleiformis and phyllocaulis boraceiensis were experimentally infected to describe the kinetics of l3 elimination in the mucus secretions of those veronicelid species. a maximum of 2 l3/g/day was found in the mucus, while the number of l3 ... | 1998 | 9612020 |
| study on the elimination of angiostrongylus costaricensis first stage larvae in the experimental infection of swiss mice. | abdominal angiostrongylosis is a nematode infection wild rodents. human infection may result in severe abdominal disease and has been reported from several countries in the americas. the domestic mouse, mus musculus, has not been found with natural infection and, like other urban rodents, should not be considered a natural host for angiostrongylus costaricensis. quantification of parasitic forms released for transmission may better express the coevolutionary status in parasite-host relationship. ... | 1998 | 9698907 |
| effects of amorphous and polymorphs of pf1022a, a new antinematode drug, on angiostrongylus costaricensis in mice. | to enhance the bioavailability of pf1022a (cyclo(d-lactyl-l-n-methylleucyl-d-3-phenyllactyl-l-n-met hylleucyl-d-lactyl-l-n-methylleucyl-d-3-phenyllactyl-l-n- methylleucyl)), a newly developed antinematode drug, we examined whether the new drug has polymorphism or not. first, four forms of pf1022a, designated as form alpha, form i, form ii and form iii of pf1022a, were prepared. by examining physicochemical properties of these forms by various methods including x-ray powder diffractometry and dif ... | 1998 | 9717771 |
| effects of nucleic acid inhibitors on the development of angiostrongylus costaricensis in vitro. | nucleic acid biosynthesis of angiostrongylus costaricensis was examined with various inhibitors; aminopterin (inhibitor of purine and pyrimidine de novo biosynthetic pathways), 8-azaguanine (specific inhibitor of purine salvage pathway) and pala (specific inhibitor of pyrimidine de novo biosynthetic pathway) were applied in in vitro culture developing from the third stage larvae to young adult in chemically defined medium. it was suggested that a. costaricensis possessed functional purine and py ... | 1998 | 9819773 |
| experimental angiostrongylus costaricensis infection in mice: immunoglobulin isotype responses and parasite-specific antigen recognition after primary low-dose infection. | immunoglobulin isotype responses and parasite-specific antigen recognition were investigated in experimental angiostrongylus costaricensis infection in two different mouse strains. even in a low-dose infection with third-stage larvae (l3), balb/c mice showed high mortality until 28 days postinfection (p.i.) in association with a low patency rate in surviving animals. on the other hand, low mortality and a high rate of patent infection was observed in c57bl/10 mice. parasite-specific igm, total i ... | 1999 | 9951963 |
| penetration sites and migratory routes of angiostrongylus costaricensis in the experimental intermediate host (sarasinula marginata). | the intermediate hosts of angiostrongylus costaricensis are terrestrian molluscs, mostly of the family veronicellidae. the present work aimed at clarifying more accurately the sites of penetration and the migratory routes of a. costaricensis in the tissue slugs and at verifying the pattern of the perilarval reaction at different times of infection. slugs were individually infected with 5,000 l1, and killed from 30 min to 30 days after infection. from 30 min up to 2 hr after infection, l1 were fo ... | 1999 | 10446018 |
| the effect of temperature on mobility of angiostrongylus costaricensis third stage larvae. | third stage larvae (l3) from angiostrongylus costaricensis were incubated in water at room temperature and at 5 degrees c and their mobility was assessed daily for 17 days. viability was associated with the mobility and position of the l3, and it was confirmed by inoculation per os in albino mice. the number of actively moving l3 sharply decreased within 3 to 4 days, but there were some infective l3 at end of observation. a mathematical model estimated 80 days as the time required to reduce the ... | 1999 | 10564915 |
| jejunal perforation caused by abdominal angiostrongyliasis. | the authors describe a case of abdominal angiostrongyliasis in an adult patient presenting acute abdominal pain caused by jejunal perforation. the case was unusual, as this affliction habitually involves the terminal ileum, appendix, cecum or ascending colon. the disease is caused by the nematode angiostrongylus costaricensis, whose definitive hosts are forest rodents while snails and slugs are its intermediate hosts. infection in humans is accidental and occurs via the ingestion of snail or slu ... | 1999 | 10602548 |
| cyclooxygenase-2-derived prostaglandin e2 and lipoxin a4 accelerate resolution of allergic edema in angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia. | in noninfected rats, challenge with allergen following local ige sensitization induced a pleurisy marked by intense protein exudation that plateaued from 30 min to 4 h after challenge, reducing thereafter. infection of rats with angiostrongylus costaricensis induced a 5-fold increase in blood eosinophil numbers by 25 days postinfection, whereas the numbers of eosinophils in the pleural cavity ranged from normal to a weak increase. in infected rats, identically sensitized, challenge with ag induc ... | 2000 | 10623853 |
| isolation of angiostrongylus costaricensis first-stage larvae from rodent feces on a percoll gradient. | several density gradients were tested for the isolation of parasitic nematode, angiostrongylus costaricensis, first-stage larvae from rodent feces. with a 45/72% percoll gradient, 83-99% (89.56+/-6.57%) of the larvae were recovered in a clean preparation. | 1999 | 10647052 |
| [eggs and reproductive organs of female angiostrongylus costaricensis are more intensely recognized by human sera from acute phase in abdominal angiostrongyliasis]. | angiostrongylus costaricensisis is an intra-arterial nematode of rodents. man may become accidentally infected through ingestion of contaminated food or water. our objective was to describe the parasite structures recognized by human antibodies in serum samples from acute and convalescent phases of abdominal angiostrongyliasis. an indirect immunofluorescent method was employed to study reactivity on whole eggs and sections of female worms and first stage larvae (l1). l1 were also studied before ... | 2003 | 12937720 |
| [parasitic helminths from sigmodon hispidus (rodentia: cricetidae) from seasonal and evergreen habitats in costa rica]. | the helminthological fauna of the cotton rat, sigmodon hispidus in a tropical environment varies according to habitat and feeding behavior. six species of nematodes (longistriata adunca, trichostrongylus sigmodontis, strongyloides sigmodontis, litomosoides carinii, monodontus sp. and protospirura sp.) and two species of cestodes (hymenolepis diminuta and raillietina sp.) were found in rats from extensive dry lands in guanacaste where hot temperatures and heterogeneous diet are the rule. only two ... | 2000 | 11021315 |
| genetic analysis of mortality in murine angiostrongyliasis costaricensis using smxa recombinant inbred mouse strains. | the smxa recombinant inbred mouse strain set was produced by systematic inbreeding from the f2 generation of a cross between two progenitor inbred strains, a/j and sm/j, which differed markedly with respect to the patterns of infection with angiostrongylus costaricensis. we have applied this set to genetic analysis of mouse susceptibility to this nematode infection. the mortality was variable among substrains of the smxa ri strains, indicating the involvement of multiple genes. linkage analysis ... | 2000 | 11077268 |
| inactivation of infective larvae of angiostrongylus costaricensis with short time incubations in 1.5% bleach solution, vinegar or saturated cooking salt solution. | angiostrongylus costaricensis is a nematode parasite of wild rodents in the americas. man may become infected accidentally and, sometimes, suffers a very severe abdominal disease. ingestion of raw vegetables has been proven to be a risk factor for the acquisition of a. costaricensis and, therefore, prophylaxis should include food disinfection. the larvicidal effect of wine vinegar, saturated cooking salt (ss) and a 1.5% bleach solution (bw) were compared with a 1-h-incubation period, at room tem ... | 2001 | 11164746 |
| potentiality of achatina fulica bowdich, 1822 (mollusca: gastropoda) as intermediate host of the angiostrongylus costaricensis morera & céspedes 1971. | samples of achatina fulica were experimentally infected with angiostrongylus costaricensis larvae, etiological agent of abdominal angiostrongyliasis, showing that a. fulica is susceptible to the parasite. achatina fulica may be a risk to urbanization of abdominal angiostrongyliasis presumably due to its high proliferation, continuous dispersion and remarkable adaptation in several brazilian towns. | 2003 | 15049117 |
| report on the occurrence of angiostrongylus costaricensis in southern brazil, in a new intermediate host from the genus sarasinula (veronicellidae, gastropoda). | veronicellid slugs are the main intermediate hosts for angiostrongylus costaricencis. in a rural locality in nova itaberaba (sc, southern brazil) sarasinula linguaeformis was identified as a crop pest. the parasitological examination revealed a. costaricencis infection in 43 out ot 50 slugs. the prevalence of 86% and the individual parasitic burdens are the highest sofar reported in brazil and s. linguaeformis is the first species from the genus sarasinula to be identified as intermediate host f ... | 2001 | 11340504 |
| angiostrongylus costaricensis life cycle: a new proposal. | | 1995 | 8731366 |
| in vitro cultivation of angiostrongylus costaricensis eggs to first stage larvae in chemically defined medium. | angiostrongylus costaricensis eggs were successfully cultured to first stage larvae in a chemically defined medium. the most suitable medium for development was ham's f-12 among 7 chemically defined media and 10 serum supplemented media examined. the addition of serum to ham's f-12 did not provide any further benefits for egg development. when the eggs were cultured in this medium under 8% co2 in air, they developed and formed larvae inside the eggs 5 days later. thereafter, the eggs began to ha ... | 1996 | 8786217 |
| evidences against a significant role of mus musculus as natural host for angiostrongylus costaricensis. | wild rodents have been described as the most important hosts for angiostrongylus costaricensis in central america and southern brazil. sinantropic rodents apparently do not play a significant role as natural hosts. a search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" mus musculus strain and groups of albino swiss mice were carried out. mortality was not significan ... | 1996 | 9163980 |
| abdominal angiostrongylosis in southern brazil--prevalence and parasitic burden in mollusc intermediate hosts from eighteen endemic foci. | angiostrongylus costaricensis is a parasitic nematode of rodents and molluscs are the intermediate hosts. nocturnal collection of molluscs and search for infective third stage larvae of a. costaricensis was carried out in 18 endemic foci identified by the notification of a confirmed diagnosis in human biopsies or surgical specimens. molluscs were digested in acidic solution and isolation of larvae eventually present was done in a baermann funnel. larvae identified by the presence of a delicate g ... | 1997 | 9302406 |
| eosinophilic ileitis with perforation caused by angiostrongylus (parastrongylus) costaricensis. a case study and review. | angiostrongylus costaricensis (classified under the more specific genus parastrongylus by different authors) is a filiform intestinal nematode endemic to central and south america, which afflicts primarily the pediatric population 1 to 13 years of age. only three cases of adult infections have been previously documented outside the endemic region. to our knowledge, we report the first such case in the western united states, as well as the oldest patient yet recorded. our patient is a 73-year-old ... | 1997 | 9302934 |
| differential responses of sm/j and a/j mice to experimental angiostrongylus costaricensis infection. | angiostrongylus costaricensis matures in mice, but shows variation in mouse mortality and worm burden among inbred strains. differences in response to infection may be controlled genetically. the patterns of infection with a. costaricensis in sm/j and a/j mouse strains differed markedly in terms of level of haematocrit and the magnitude of splenomegaly. | 1997 | 9421732 |
| effect of angiostrongylus costaricensis extract on eosinophilic pulmonary response in balb/c mice. | epidemiological and experimental studies have demonstrated an association between parasitic infections and the allergic diseases. a protective effect in asthma was shown in animals infected with helminths. the aim of this study was to determine the effect of angiostrongylus costaricensis extract on inflammatory lung response to ovalbumin (ova) in mice. four balb/c mice received a. costaricensis extract by intraperitoneal (i.p.) injection on the first day. mice were immunised against ova by i.p. ... | 2006 | 16362342 |
| chromosomal mapping of host susceptibility loci to angiostrongylus costaricensis nematode infection in mice. | angiostrongylus costaricensis is a nematode found mainly as a rodent parasite. laboratory mice were experimentally infected with this parasite. it is known that there is great variability in mortality among inbred mouse strains after infection with this nematode. the survival rate at 5 weeks after infection of a/j mice was 90.5%, whereas that of sm/j mice was only 33.3%, with severe anemia and decreased body weight about 3 weeks after infection. to identify host susceptibility genes for infectio ... | 2002 | 11862393 |
| natural infection of deroceras laeve (mollusca: gastropoda) with metastronbylid larvae in a transmission focus of abdominal angiostrongyliasis. | angiostrongylus costaricensis is a nematode parasitic of rodents. man may become infected by ingestion of the third stage larvae produced within the intermediate hosts, usually slugs from the family veronicellidae. an epidemiological study carried out in a locality in southern brazil (western santa catarina state) where these slugs are a crop pest and an important vector for a. costaricensis has documented for the first time the natural infection of deroceras laeve with metastrongylid larvae. th ... | 2002 | 11896413 |
| dogs may be a reservoir host for angiostrongylus costaricensis. | angiostrongylus costaricensis is a parasitic nematode of wild rodents. several other vertebrate species including man may become infected by ingestion of the third stage larvae produced by the intermediate hosts, usually slugs from the family veronicellidae. there is a report of the diagnosis of abdominal angiostrongyliasis in canis familiaris with lesions resembling those found in human disease. as a preliminar evaluation of the adequacy of a canine model for pathogenetic studies, a dog was ino ... | 2002 | 11896414 |
| interleukin-5 transgenic mice show augmented resistance to angiostrongylus costaricensis infection. | to determine the possible role of eosinophils in angiostrongylus costaricensis infection, both interleukin-5 (il-5) transgenic (tg) and non-transgenic (non-tg) c3h/hen mice were infected with a. costaricensis third-stage larvae. il-5 tg mice demonstrated greater resistance than non-tg mice to a. costaricensis, as shown by lower adult worm recovery, smaller adults, fewer eggs in the intestinal wall and fewer larvae passed in the feces. both mice showed similar antigen-specific iga and iggi antibo ... | 2002 | 11999023 |
| angiostrongylus costaricensis life cycle in the intermediate host sarasinula marginata semper, 1885 (mollusca: soleolifera). | | 2002 | 12011932 |
| human infection by angiostrongylus costaricensis in venezuela: first report of a confirmed case. | a proven case of human infection caused by angiostrongylus costaricensis is reported for the first time in venezuela. the patient was a 57-year-old female surgically operated because of signs of peritonitis with a palpable mass at the lower right quadrant of the abdomen. wbc count reported 16,600 cells/mm3, with 46% eosinophils. the tumoral aspect of ileocolic area and peritoneal lymph nodes prompted the resection of a large area of the terminal ileum, cecum, part of the ascending colon and a sm ... | 2007 | 17625700 |
| mouse h2 haplotype influences on the survival rate after angiostrongylus costaricensis infection. | | 2002 | 12054705 |
| first record of a nematode metastrongyloidea (aelurostrongylus abstrusus larvae) in achatina (lissachatina) fulica (mollusca, achatinidae) in brazil. | achatina (lissachatina) fulica was introduced in brazil in the 1980s for commercial purposes ("escargot" farming) and nowadays, mainly by human activity, it is widespread in at least 23 out of 26 brazilian states and brasília, including the amazonian region and natural reserves, where besides a general nuisance for people it is a pest and also a public health concern, since it is one of the natural intermediate host of angiostrongylus cantonensis, ethiological agent of the meningoencephalitis in ... | 2008 | 18078952 |
| angiostrongylus costaricensis n. sp. (nematoda: metastrongyloidea), a new lungworm occuring in man in costa rica. 1971. | | 2002 | 12362902 |
| [necrotic eosinophilic angiitis with ileal perforation and peritonitis secondary to abdominal angiostrongyliasis]. | abdominal angiostrongyliasis caused by the filiform nematode angiostrongylus costaricensis, is an endemic disease in central and south america. a case of necrotic eosinophilic angeitis with ileum perforation and peritonitis due to abdominal angiostrongyliasis is reported. | 2002 | 12467150 |
| intestinal granuloma formation in normal and scid balb/c mice infected with angiostrongylus costaricensis. | we studied the histomorphology of granuloma formation and cytokine production in angiostrongylus costaricensis-infected immunocompetent and immunodeficient balb/c mice. histological examination of the infected intestine showed well developed granulomas in balb/c mice. in contrast, in scid mice, clusters of eggs and larvae and a progression of infiltration of inflammatory cells were also observed, but little fibroblastic activity was seen. analysis of plasma of the infected mice demonstrated a dr ... | 2003 | 12489016 |
| angiostrongylus costaricensis infection in c57bl/6 mice: mhc-ii deficiency results in increased larval elimination but unaltered mortality. | during experimental angiostrongylus costaricensis infections in several inbred mouse strains, genetic factors as well as different cytokine secretion patterns have recently been shown to play a role in the outcome of infection in terms of morbidity and mortality, e.g. balb/c mice show a high and c57bl/6 mice a low mortality during the acute phase of infection. in this study, c57bl/6 mhc-ii knockout mice infected with a. costaricensis did not show increased mortality during the acute phase of inf ... | 2003 | 12750994 |
| kinetics of eosinophil and ige-mast cell changes following infection with angiostrongylus costaricensis in wistar rats. | human abdominal angiostrongyliasis is a severe eosinophilic disease caused by angiostrongylus costaricensis. previous studies have demonstrated that wild rodents are critically involved as definitive hosts to this nematode in nature. in this study, we have evaluated the susceptibility of wistar rats (rattus norvegicus) to a. costaricensis infection. kinetics of parasitological and pathological changes, including the number of adult worms recovered from mesenteric arteries, and of ige, mast cell ... | 2003 | 12911525 |
| diagnosis of abdominal angiostrongyliasis by pcr from sera of patients. | abdominal angiostrongyliasis is a zoonotic infection caused by an intra-vascular nematode parasitic of wild rodents, angiostrongylus costaricensis. no parasitological diagnosis is currently available and immunodiagnosis presents several drawbacks. primers constructed based on a congeneric species, a. cantonensis, were able to amplify a 232 bp fragment from serum samples of 3 patients with histopathological diagnosis. extraction was better performed with dnazol and the specificity of the primers ... | 2003 | 14743672 |
| angiostrongylus costaricensis and experimental infection of sarasinula marginata ii: elimination routes. | angiostrongylus costaricensis intermediate hosts are terrestrial mollusks mostly belonging to the veronicellidae family. in the present investigation we focused on the mechanisms of larval expulsion from sarasinula marginata infected with a. costaricensis. twenty-five mollusks were individually infected with 5000 l1 and sacrificed at 30 min and 1, 2, 4, 6, and 8 h post-infection and at days 1, 2, 4, 5, 6, 8, 10, 11, 12, 14, 15, 16, 20, 21, 22, 25, 26, 28, and 30 post-infection; the mollusks were ... | 2004 | 14762514 |
| molecular differentiation of angiostrongylus costaricensis, a. cantonensis, and a. vasorum by polymerase chain reaction-restriction fragment length polymorphism. | angiostrongylus cantonensis, a. costaricensis, and a. vasorum are etiologic agents of human parasitic diseases. their identification, at present, is only possible by examining the adult worm after a 40-day period following infection of vertebrate hosts with the third-stage larvae. in order to obtain a diagnostic tool to differentiate larvae and adult worm from the three referred species, polymerase chain reaction-restriction fragment length polymorphism was carried out. the rdna second internal ... | 2004 | 15049087 |
| effectiveness of intranasal vaccination against angiostrongylus costaricensis using a serine/threonine phosphatase 2 a synthetic peptide and recombinant antigens. | intranasal immunization was assayed in c57bl/6 mice against angiostrongylus costaricensis using a synthetic and a recombinant peptide belonging to the catalytic region of the serine/threonine phosphatase 2 a (pp2a) of the parasite. immunization was carried out with the synthetic peptide (sp) polymerized either with itself or with the beta fraction of the cholera toxin (ctb) and then enclosed in nanocapsules of phosphatidyl choline, cholesterol and quil a (iscom). another group of mice was immuni ... | 2010 | 20558243 |
| long-term observations on mouse strains experimentally infected with angiostrongylus costaricensis. | balb/c and c57bl/6 mice were experimentally infected with angiostrongylus costaricensis and the parasitic parameters and antibody response during the acute and chronic phases of infection were analyzed. following administration of six third-stage larvae (l3), there was no significant difference in the mean worm recovery or mean larval output. coinciding with the maturation of worms in infected animals and with the egg output in mesenteric arteries, a strong increase in the humoral immune respons ... | 2004 | 15138807 |
| treatment with mebendazole is not associated with distal migration of adult angiostrongylus costaricensis in the murine experimental infection. | abdominal angiostrongyliasis is a zoonotic infection produced by a metastrongylid intra-arterial nematode, angiostrongylus costaricensis. human accidental infection may result in abdominal lesions and treatment with anti-helminthics is contra-indicated because of potential higher morbidity with excitement or death of worms inside vessels. to evaluate the effect of mebendazole on localization of the worms, male swiss mice, 5 week-old, were infected with 10 third stage larvae per animal. twelve in ... | 2004 | 15141273 |
| detection of anti-oxidant enzymatic activities and purification of glutathione transferases from angiostrongylus cantonensis. | there are several anti-oxidant enzyme families that play pivotal roles in facilitating the survival of parasites. glutathione transferases (gsts) are members of the anti-oxidant family that can detoxify a broad range of exogenous or endogenous compounds including reactive oxidative species. gsts have been studied as vaccine candidates, immunodiagnostic markers and as treatment targets. helminths of the genus angiostrongylus live inside arteries of vertebrates and two main species are associated ... | 2011 | 20807531 |
| angiostrongyliasis: analysis of antigens of angiostrongylus costaricensis adult worms versus igg from infected patients with angiostrongylus cantonensis. | the possibility of cross-reactivity was previously investigated by indirect elisa with sera from angiostrongylus cantonensis infections, normal controls and a. costaricensis antigen. 5 microg/ml of crude antigen from both sexes of each species reacted with diluted serum samples (1:800) of each of 20 cases of angiostrongyliasis and normal controls, and further with anti-human igg conjugate at 1:1,000. the mean absorbance values were evaluated as follows; normal controls showed a value of 0.033 us ... | 2000 | 11414459 |
| cellular immune responses and cytokine production in balb/c and c57bl/6 mice during the acute phase of angiostrongylus costaricensis infection. | in our experimental study we were able to show that the contrasting outcome of angiostrongylus costaricensis infection in c57bl/6 and balb/c mice, in respect of morbidity and mortality, can be explained by divergent cellular immune responses and a different cytokine pattern in each strain. in balb/c mice (i.e. those with high mortality), the initial high proliferation of cona or lps stimulated spleen cells dropped to very low levels after 2 weeks post-infection (p.i.), whereas in c57bl/6 mice (i ... | 2001 | 11495645 |
| effects of anthelmintics on the development of eggs of angiostrongylus costaricensis in vitro. | effects of the anthelmintics, pyrantel and levamisole, on egg development of angiostrongylus costaricensis were studied in vitro. after 7 days, about 80% of eggs developed to first-stage larvae in ham's f-12 medium with 10% foetal calf serum under 5% co2. significant inhibition of development was caused by pyrantel (10(-9) - 10(-8) g ml(-1)) and levamisole (10(-9) - 10(-8) g ml(-1)) (mann-whitney u-test; ), and none of the eggs developed to first-stage larvae in higher concentrations of these an ... | 2001 | 11818052 |