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heteroduplex mobility assay detects dna mutations for differentiation of closely related phytoplasma strains.we present the first use of dna heteroduplex mobility assay (hma) to detect the point mutations including substitutions and deletions/insertions in 16s rdna of aster yellows phytoplasma (ay27) and to differentiate phytoplasmas collected from field samples of clover proliferation (cp) and alfalfa witches'-broom (awb). the phytoplasmal 16s rdna fragment was amplified from ay27 by polymerase chain reaction (pcr) and cloned into a plasmid vector. the cloned dna fragment was subjected to in vitro mut ...200010856778
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