description of babesia duncani n.sp. (apicomplexa: babesiidae) from humans and its differentiation from other piroplasms.the morphologic, ultrastructural and genotypic characteristics of babesia duncani n.sp. are described based on the characterization of two isolates (wa1, ca5) obtained from infected human patients in washington and california. the intraerythrocytic stages of the parasite are morphologically indistinguishable from babesia microti, which is the most commonly identified cause of human babesiosis in the usa. intraerythrocytic trophozoites of b. duncani n.sp. are round to oval, with some piriform, ri ...200616725142
comparison of the babesia duncani (wa1) igg detection rates among clinical sera submitted to a reference laboratory for wa1 igg testing and blood donor specimens from diverse geographic areas of the united states.all reported cases of wa1 babesiosis have occurred in the pacific coast region of the united states, suggesting that wa1 is limited to this geographic area. however, we detected wa1 igg in 27% of clinical sera sent to our laboratory for wa1 igg testing from across the united states over a 2-year period, suggesting that exposure to wa1 or a closely related organism occurs outside pacific coast states. we sought to determine if this high wa1 igg detection rate among clinical specimens merely refle ...201020861326
The third described case of transfusion-transmitted Babesia duncani.BACKGROUND: Almost all of the reported US tick-borne and transfusion-associated Babesia cases have been caused by Babesia microti, which is endemic in the Northeast and upper Midwest. We investigated a case caused by B. duncani (formerly, the WA1-type parasite), in a 59-year-old California resident with sickle cell disease (HbSS) whose only risk factor for infection was receipt of red blood cell transfusions. CASE REPORT: The patient's case was diagnosed in September 2008: intraerythrocytic para ...201122168221
emerging incidence of lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in australia.borrelia burgdorferi, the causative agent of lyme disease (ld), and babesia, bartonella, and ehrlichia species (spp.) are recognized tick-borne pathogens in humans worldwide. using serology and molecular testing, the incidence of these pathogens was investigated in symptomatic patients from australia.201122267937
development of droplet digital pcr for the detection of babesia microti and babesia duncani.babesia spp. are obligate protozoan parasites of red blood cells. transmission to humans occurs through bites from infected ticks or blood transfusion. infections with b. microti account for the majority of the reported cases of human babesiosis in the usa. a lower incidence is caused by the more recently described species b. duncani. the current gold standard for detection of babesia is microscopic examination of blood smears. recent pcr-based assays, including real-time pcr, have been develope ...201425500215
chronic coinfections in patients diagnosed with chronic lyme disease: a systematic review.often, the controversial diagnosis of chronic lyme disease is given to patients with prolonged, medically unexplained physical symptoms. many such patients also are treated for chronic coinfections with babesia, anaplasma, or bartonella in the absence of typical presentations, objective clinical findings, or laboratory confirmation of active infection. we have undertaken a systematic review of the literature to evaluate several aspects of this practice.201424929022
redescription of babesia ardeae toumanoff, 1940, a parasite of ardeidae, including molecular characterization.among the actual 16 identified and thought to be valid avian piroplasm species, certain parasites are only known from their original description with no subsequent report. babesia ardeae toumanoff, 1940 is one of them. it was described from a single sacrificed gray heron (ardea cinerea) from vietnam and had never been reported since this date despite inhabiting a very common avian host. the present study reports the accidental rediscovery of b. ardeae from an injured wild gray heron rescued in s ...201728160075
transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia.the intracellular parasites babesia microti and babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease. the rarity of the diagnosis, as well as its similar clinical presentation to delayed hemolytic transfusion reaction, may lead to a delay in diagnosis, as well as inappropriate treatment with steroids or other immunosuppressive agents. the morbidity caused by this disease in espec ...201728766838
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