| multiplolides a and b, new antifungal 10-membered lactones from xylaria multiplex. | two new 10-membered lactones, namely, multiplolides a (1) and b (2), were isolated from the broth extract of the fungus xylaria multiplex bcc 1111. chemical structures of 1 and 2 were elucidated on the basis of their spectral data. multiplolides a (1) and b (2) exhibited antifungal activity against candida albicans with ic(50) values of 7 and 2 microg/ml, respectively. both 1 and 2 were inactive in the screening systems toward the malarial parasite plasmodium falciparum (at 20 microg/ml) and wer ... | 2001 | 11473437 |