Publications

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[diversity of actinomycetes in wuling mountain].to isolate new actinomycetes for discovering compounds of pharmaceutical importance.200818837376
sphaerisporangium flaviroseum sp. nov. and sphaerisporangium album sp. nov., isolated from forest soil in china.two gram-positive, aerobic actinomycete strains, designated yim 48771(t) and yim 48782(t), were isolated from virgin forest soil samples collected in hunan province, china. 16s rrna gene sequence similarities of the two novel isolates ranged from 96.3 to 97.6 % with species of the genus sphaerisporangium with validly published names but, in the tree based on 16s rrna gene sequences, the isolates formed distinct phyletic lines. the level of 16s rrna gene sequence similarity between the two novel ...200919542141
bioconversion of as1387392: screening and characterization of actinomycetes that convert as1387392 to as1429716.as1387392 was a novel and powerful histone deacetylase inhibitor with an excellent oral absorption profile, but this compound was lacking in active moieties, which are essential to synthesize more derivatives. in our screening program to identify actinomycetes capable of converting as1387392 to as1429716, which has an active moiety to synthesize more derivatives, we identified 12 strains capable of efficient hydroxylation. results of phylogenetic analysis of 16s rdna sequences suggested that the ...201020664604
sphaerisporangium siamense sp. nov., an actinomycete isolated from rubber-tree rhizospheric soil.a gram-positive aerobic actinomycete, designated sr14.14(t), isolated from the rhizospheric soil of rubber tree was determined taxonomically using a polyphasic approach. the organism contained meso-diaminopimelic acid and the n-acetyl type of peptidoglycan. the predominant menaquinones were mk-9, mk-9(h2) and mk-9(h4). madurose was detected in the whole-cell hydrolysates. mycolic acids were not presented. major phospholipids were diphosphatidylglycerol, phosphatidylethanolamine and phosphatidyli ...201121407236
sphaerisporangium krabiense sp. nov., isolated from soil in thailand.a gram-staining-positive, filamentous bacterial strain was isolated from tropical mangrove forest soil, thailand. strain a-t 0308(t) developed spherical globose sporangia containing non-motile spores on aerial mycelium. the novel strain contained meso-diaminopimelic acid, and the n-acetyl type of peptidoglycan, the whole-cell hydrolysates contained madurose, mannose, ribose, galactose and glucose as whole-cell sugars. predominant menaquinones were mk-9(h4) and mk-9(h6), and small amount of mk-9( ...201121257689
biosynthetic potential of phylogenetically unique endophytic actinomycetes from tropical plants.the culturable diversity of endophytic actinomycetes associated with tropical, native plants is essentially unexplored. in this study, 123 endophytic actinomycetes were isolated from tropical plants collected from several locations in papua new guinea and mborokua island, solomon islands. isolates were found to be prevalent in roots but uncommon in leaves. initially, isolates were dereplicated to the strain level by ribotyping. subsequent characterization of 105 unique strains by 16s rrna gene s ...201020472734
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