Publications

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biochemical evaluation of feeding trichosanthes dioica seeds in normal and mild diabetic human subjects in relation to lipid profile. 19902253986
effect of trichosanthes dioica on oxidative stress and cyp450 gene expression levels in experimentally induced diabetic rats.the present study is a systematic and scientific evaluation of antioxidant potential of aqueous extract of trichosanthes dioica fruits on diabetes induced oxidative stress of severely diabetic rats. its effect on gene expression level of the tissue—specific cytochrome p450 (cyp) was also studied. the dose of 1000mg/kg bw of t. dioica extract was administered orally once a day for 28 days to severely diabetic rats. various oxidative stress parameters were analyzed in selected tissues of control a ...201121366960
purification and characterization of a novel chitinase from trichosanthes dioica seed with antifungal activity.chitinases are a group of enzymes that show differences in their molecular structure, substrate specificity, and catalytic mechanism and widely found in organisms like bacteria, yeasts, fungi, arthropods actinomycetes, plants and humans. a novel chitinase enzyme (designated as tdsc) was purified from trichosanthes dioica seed with a molecular mass of 39±1 kda in the presence and absence of β-mercaptoethanol. the enzyme was a glycoprotein in nature containing 8% neutral sugar. the n-terminal sequ ...201626666429
paralytic and lethal effects of trichosanthes dioica root extracts in experimental worms.trichosanthes dioica roxb. (cucurbitaceae), called pointed gourd in english, is a dioecious climber and its roots are traditionally used in india as a hydrogouge cathartic, tonic, and febrifuge, and in the treatment of jaundice, anasarca, and ascites.201020695728
hypoglycemic effect of aqueous extract of trichosanthes dioica in normal and diabetic rats.trichosanthes dioica is used to treat diabetes mellitus, epilepsy, alopecia, and skin disease in folklore medicine. the leaf extract of the plant is used in diabetes mellitus but there have been no scientific studies reported.201020431805
libs-based detection of antioxidant elements: a new strategy.the present study deals with the scientific evaluation of antioxidant potential of aqueous extract of trichosanthes dioica fruits on diabetes-induced oxidative stress of diabetic rats. the most effective dose of mg/kg bw of fruit aqueous extract was given orally to diabetic rats for 30 days. different oxidative stress parameters were analyzed in various tissues of control and treated diabetic rats. the observed elevated level of lipid peroxidation (lpo) comes down significantly (p < 0.05) and de ...201020072924
evaluation of possible health risks of heavy metals by consumption of foodstuffs available in the central market of rajshahi city, bangladesh.considering the human health risk due to the consumption of foodstuffs, the concentrations of heavy metals (lead, manganese, chromium, cadmium, and arsenic) are investigated in vegetables, fruits, and fish species collected from the central market (called shaheb bazar) of rajshahi city, bangladesh. the foodstuffs examined for metal constituents are the basis of human nutrition in the study area. the highest concentrations of mn and as in vegetables (onion and pointed gourd, respectively), cr and ...201322933105
wound healing potential of methanolic extract of trichosanthes dioica roxb (fruits) in rats.the present study provides a scientific evaluation for the wound healing potential of methanolic (meoh) extract of tdr fruits.201020006696
evaluation of in vitro cytotoxic effect of trichosanthes dioica root.trichosanthes dioica roxb. (cucurbitaceae), called pointed gourd in english is a dioecious climber grown in india and used traditionally for various medicinal purposes.201021713138
determination of cadmium, lead and zinc in vegetables in jaipur (india).an atomic absorption spectroscopic method was used for the determination of lead, cadmium and zinc in vegetables grown in and around jaipur food stuffs irrigated with industrial waste water. vegetable samples were collected after maturity, and analyzed, such as spinach (spinacia oleracea), ladyfinger (abelmoschus esulentus), pepper mint (menthe pipereta), brinjal (solanum melongena), coriander (coriandrum sativum), cauliflower (brassica oleracea), onion (allium cepa), radish (raphanus sativus), ...201426445755
preliminary observations on serum biochemical parameters of albino rabbits fed on seeds of trichosanthes dioica (roxb). 19883169897
the triterpenoid fraction from trichosanthes dioica root exhibits in vitro antileishmanial effect against leishmania donovani promastigotes.trichosanthes dioica roxb. (cucurbitaceae), called pointed gourd in english is a dioecious climber found wild throughout the plains of the indian subcontinent and traditionally used in india for several medicinal purposes.201323798885
effect of raw deseeded fruit powder of trichosanthes dioica (roxb) on blood sugar, serum cholesterol, high density lipo-protein, phospholipid and triglyceride levels in the normal albino rabbits. 19883182065
taxonomic significance of trichomes micromorphology in cucurbits.studies on trichomes micromorphology using scanning electron microscope (sem) were undertaken in 23 species with one variety under 13 genera of the family cucurbitaceae (viz., benincasa hispida (thunb.) cogn., citrullus lanatus (thunb.) matsum. & nakai, cucumis melo var. agrestis naudin, cucumis sativus l., diplocyclos palmatus (l.) c. jeffrey, edgaria dargeelingensis c.b. clarke, gynostemma burmanicum king ex chakr., gynostemma pentaphyllum (thunb.) makino, gynostemma pubescens (gagnep.) c.y. w ...201123961108
on the safe use of pesticides in controlling the terrestrial mollusc pests.the preferred food items of the slugs laevicaulis alte and the snails achatina fulica were used to prepare 'poison baits' by injecting the pesticides 'rogor' and 'nuvan' to kill these mollusc pests. the 'poison baits' prepared with trichosanthes dioica and lycopersicum esculentum were accepted by 100% individuals of both the species irrespective of the pesticides used. in all cases the slug and snail individuals died within a considerable length of time following consumption of the bait. the imp ...19938107590
antitumor efficacy and amelioration of oxidative stress by trichosanthes dioica root against ehrlich ascites carcinoma in mice.context: trichosanthes dioica roxb. (cucurbitaceae) is a dioecious climber, traditionally used in india for several medicinal purposes. objective: the present study assessed the hydroalcoholic extract of t. dioica root (tda) for antitumor effect and antioxidant influence against ehrlich ascites carcinoma (eac) in swiss albino mice. methods: twenty four hours after intraperitoneal inoculation of tumor (eac) cells in mice, tda was administered at 5 and 10ôçëmg/kg body weight daily for 9 consecutiv ...201121819262
trichosanthes dioica root extract induces tumor proliferation and attenuation of antioxidant system in albino mice bearing ehrlich ascites carcinoma.trichosanthes dioica roxb. (cucurbitaceae), called pointed gourd in english, is a dioecious climber grown widely in the indian subcontinent. the present study assessed the influence of treatment of hydroalcoholic extract of trichosanthes dioica root (tda) on ehrlich ascites carcinoma (eac) in swiss albino mice with effects on antioxidant systems. twenty-four hours after intraperitoneal inoculation of tumor (eac) cells in mice, tda was administered at 25 and 50 mg/kg for 8 consecutive days. on th ...201122319252
trichosanthes dioica root possesses stimulant laxative activity in mice.trichosanthes dioica roxb. (cucurbitaceae), named 'pointed gourd' in english, is a dioecious climber grown in india. this study was aimed at evaluating the laxative activity of the aqueous extract of t. dioica root (tda) in swiss albino mice. the laxative activity of tda (100 and 200ôçëmgôçëkg(-1) body weight per os) was evaluated by assessing the excretory bowel activities in naive (non-constipated) and in drug (loperamide)-induced constipation in mice. further, the gastrointestinal transit was ...201121827370
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