| occurrence of hemolytic activity in the skin secretion of the caecilian siphonops paulensis. | the skin secretion of the caecilian siphonops paulensis (spss) induces a time-and dose-dependent hemolytic response on red blood cells (rbc). when rbc from various animals species were subjected to the action of spss, a range of sensitivities was evident, sheep erythrocytes being the most susceptible, human, mouse and rabbit having moderate susceptibility, cow, snake and toad erythrocytes being more resistant, while s. paulensis rbc were entirely resistant. the hemolytic activity of spss was inh ... | 1998 | 10398514 |
| skin secretion of siphonops paulensis (gymnophiona, amphibia) forms voltage-dependent ionic channels in lipid membranes. | the effect of the skin secretion of the amphibian siphonops paulensis was investigated by monitoring the changes in conductance of an artificial planar lipid bilayer. skin secretion was obtained by exposure of the animals to ether-saturated air, and then rinsing the animals with distilled water. artificial lipid bilayers were obtained by spreading a solution of azolectin over an aperture of a delrin cup inserted into a cut-away polyvinyl chloride block. in 9 of 12 experiments, the addition of th ... | 2003 | 12937797 |
| indirect cardiotoxic activity of the caecilian siphonops paulensis (gymnophiona, amphibia) skin secretion. | the skin secretion of the caecilian s. paulensis has an indirect cardiotoxic effect. it induces a rapid blockage of electrical activity and subsequent diastolic arrest on in situ toad heart preparations. this action is not blocked by atropine and is therefore not mediated through a cholinergic mechanism. in addition, s. paulensis skin secretion is ineffective in inducing any response in isolated perfused toad heart assay, in the spontaneously beating isolated toad atria or in the electrically dr ... | 1999 | 9920479 |