| use of an amoeba proteus model for in vitro cytotoxicity testing in phytochemical research. application to euphorbia hirta extracts. | amoeba proteus is proposed as a low-cost multi-purpose biochemical tool for screening and standardizing cytotoxic plant extracts with possible application in the laboratories of developing countries. advantages and limitations of this test are examined and different mathematical treatments (probit analysis versus curve fitting to von bertalanffy and hill functions) are investigated. known anti-cancer (doxorubicin, daunorubicin, dacarbazine, 5-fluorouracil) and antiparasitic (emetine, dehydroemet ... | 1991 | 1686625 |
| analgesic, antipyretic and anti-inflammatory properties of euphorbia hirta. | lyophilised aqueous extract of euphorbia hirta l. (euphorbiaceae) has been evaluated for analgesic, antipyretic and anti-inflammatory properties in mice and rats, in order to complete its activity profile, after the confirmation of the existence of a central depressant activity particularly expressed by a strong sedative effect, associated with anxiolytic effects. this study leads us to the conclusion that this plant extract exerts central analgesic properties. such a dose-dependent action was o ... | 1991 | 1896520 |
| behavioral effects of euphorbia hirta l.: sedative and anxiolytic properties. | lyophilised aqueous extract of euphorbia hirta l. (euphorbiaceae) has been evaluated for behavioral effects in mice. the extract did not induce any toxic effect when it was administered i.p. and orally. sedative properties could be confirmed with high doses (100 mg of dried plant/kg, and more), by a decrease of behavioral parameters measured in non-familiar environment tests (activitest and staircase test), whereas anticonflict effects appeared at lower doses (12.5 and 25 mg of dried plant/kg), ... | 1990 | 1973750 |
| [polyphenols from leaves of euphorbia hirta l]. | six compounds have been isolated from the leaves of euphorbia hirta and identified as gallic acid, quercitrin, myricitriu, 3,4-di-o-galloylquinic acid, 2,4,6-tri-o-galloyl-d-glucose and 1,2,3,4, 6-penta-o-galloyl-beta-d-glucose on the basis of physicochemical and spectroscopic methods. | 1991 | 2069701 |
| [note on 2 african drugs with confirmed amebicidal properties: holarrhens floribunda and euphorbia hirta]. | | 1969 | 5399292 |
| a chemical examination of euphorbia hirta linn. | | 1966 | 5978708 |
| influence of some traditional medicinal plants of senegal on prostaglandin biosynthesis. | aqueous extracts of combretum micranthum g. don, euphorbia hirta l., guiera senegalensis lam. and melaleuca leucadendron l. were investigated for their influence on prostaglandin biosynthesis (pg i2, pg e2, pg d2). only the extract of euphorbia hirta strongly reduced the release of prostaglandins i2, e2, and d2. additionally euphorbia hirta extracts exerted an inhibitory effect on platelet aggregation and depressed the formation of carrageenin induced rat paw oedema. the chemical nature of the a ... | 1994 | 7980813 |
| antidiarrhoeic activity of quercitrin in mice and rats. | quercitrin, a flavonoid isolated from euphorbia hirta, shows antidiarrhoeic activity at doses of 50 mg kg-1, against castor oil- and pge2-induced diarrhoea in mice, but not when magnesium sulphate is used as a cathartic agent. it also delays rat small intestinal transit if this is accelerated with castor oil. however, the flavonoid does not modify the fluid transport across the colonic mucosa when it is administered intraluminally, either in normal conditions or when this transport is altered by ... | 1993 | 8095537 |
| antidiarrhoeic activity of euphorbia hirta extract and isolation of an active flavonoid constituent. | the antidiarrhoeic activity of the euphorbia hirta whole plant was investigated. the lyophilized decoction demonstrated antidiarrhoeic activity in experimental models of diarrhoea induced by castor oil, arachidonic acid, and prostaglandin e2. it showed no activity when magnesium sulphate was used to provoke the diarrhoea. the lyophilized decoction delayed small intestinal transit when this was accelerated by castor oil but not in normal conditions. a flavonoid, quercitrin, with antidiarrhoeic ac ... | 1993 | 8372151 |
| antibacterial effect of theaflavin, polyphenon 60 (camellia sinensis) and euphorbia hirta on shigella spp.--a cell culture study. | antibacterial effect of compounds extracted from camellia sinensis l. and the methanol extract of euphorbia hirta l. were studied against dysentery causing shigella spp. using the vero cell line. cytotoxicity studies of the extracts were performed using the cell line and the non-cytotoxic concentration of the extract was tested for antibacterial activity against the cytopathic dose of the pathogen. these extracts were found to be non-cytotoxic and effective antibacterial agents. | 1995 | 8847884 |
| euphorbia hirta leaves and musa sapientum fruits in culture media for fungi. | two plant products, euphorbia hirta leaves and fruits of musa sapientum, were evaluated as principal ingredients for selective cultivation of fungi. sapientum glucose agar supported the growth of both dermatophytic, yeast-like, and saprophytic fungi; growth on this medium compared favourably with growth on sabouraud glucose agar, a standard mycological medium. sporulation and pigment formation were stronger on sapientum glucose agar than on sabouraud glucose agar, although fungal growth on the l ... | 1998 | 9919898 |
| biological screening of traditional preparations from some medicinal plants used as antidiarrhoeal in kinshasa, congo. | forty six aqueous extracts from 38 medicinal plant species belonging to different families were selected on the basis of their traditional medicinal use as antidiarrhoeic agents. they were submitted in a broad biological screening including antibacterial, antiamoebic and antispasmodic activities. the results of the testing have indicated that 37 extracts (80.43%), 33 (71.74%) and 32 (69.54%) exhibited some level of antibacterial, antiamoebic and antispasmodic activity respectively. only 8 plant ... | 1999 | 10228613 |
| euphorbia hirta leaf extracts increase urine output and electrolytes in rats. | euphorbia hirta is locally used in africa and australia to treat numerous diseases, including hypertension and edema. the diuretic effect of the e. hirta leaf extracts were assessed in rats using acetazolamide and furosemide as standard diuretic drugs. the water and ethanol extracts (50 and 100 mg/kg) of the plant produced time-dependent increase in urine output. electrolyte excretion was also significantly affected by the plant extracts. the water extract increased the urine excretion of na+, k ... | 1999 | 10350369 |
| antimalarial activity of 20 crude extracts from nine african medicinal plants used in kinshasa, congo. | twenty extracts including ten etoh and ten ch2cl2 from different parts of nine african medicinal plants used in congolese traditional medicine for the treatment of malaria, were submitted to a pharmacological test in order to evaluate their effect on p. falciparum growth in vitro. of these plant species, 14 (70%) extracts including etoh and ch2cl2 from cassia occidentalis leaves, cryptolepis sanguinolenta root bark, euphorbia hirta whole plant, garcinia kola stem bark and seeds, morinda lucida l ... | 1999 | 10624878 |
| antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in kinshasa, congo. | three major extracts from some traditional preparations, based on medicinal plants, used as antidiarrhoeal agents were investigated for their putative antiamoebic and spasmolytic activities in vitro. results indicated that both biological activities are concentrated in the polyphenolic fraction, and not in the saponin or alkaloid containing fractions. the most active polyphenolic extracts were those from euphorbia hirta whole plant, leaves of alchornea cordifolia, crossopteryx febrifuga, nauclea ... | 2000 | 10782488 |
| [identification of a confused species of euphorbia hirta l. e. indica lam]. | the article reported the morphological and histological identification for euporbia hirta l. and its confused species e. indica lam.. it provided evidences for identifying euphorbia hirta l.. | 2001 | 11341025 |
| [the antidysenteric properties of euphorbia hirta]. | | 1964 | 14144081 |
| [therapeutic action of euphorbia hirta extracts in intestinal amebiasis. apropos of 150 cases]. | | 1964 | 14181745 |
| morphometric and histopathological studies on the effects of some chromatographic fractions of phyllanthus amarus and euphorbia hirta on the male reproductive organs of rats. | the aqueous crude extracts of p. amarus and e. hirta were administered to thirty eight-week old sexually mature male albino to determine the effects of these extracts on the male reproductive organs of these animals. the results from this study revealed that the aqueous crude extracts of p. amarus and e. hirta caused varying degrees of testicular degeneration as well as reduction in the mean seminiferous tubular diameter (std) in the treated rats. it thus shows that the aqueous crude extracts of ... | 2003 | 14610373 |
| effects of coal-smoke pollutants from different sources on the growth, chlorophyll content, stem anatomy and cuticular traits of euphorbia hirta l. | variations occurred in the growth, assimilate partitioning, chlorophyll content, stem anatomy and leaf cuticular traits of euphorbia hirta l. on long-term exposure to coal-smoke pollutants prevailing at two sites, one situated close to a railway loco shed (site b) and another in the vicinity of a thermal power plant (site c). the botanical garden of aligarh muslim university, aligarh, was considered as a control site (a). site c possessed a greater load of coal-smoke pollutants than site b. the ... | 1987 | 15092709 |
| in vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the democratic republic of congo. | the in vitro antiplasmodial activity of seven etoh extracts and twenty fractions from the partition of the initial ethanolic extracts from seven african medicinal plants used in the democratic republic of congo (dr congo) for the treatment of malaria was evaluated. the most active etoh extracts (ic50 < 3 microg/ml) were those from cassia occidentalis leaves, euphorbia hirta whole plant, garcinia kola stem bark and phyllanthus niruri whole plant. their respective petroleum ether soluble fractions ... | 2004 | 15182900 |
| [repellent and antifeedant effect of secondary metabolites of non-host plants on plutella xylostella]. | based on the theory of co-evolution between plants and phytophagous insects, the repellent and antifeedant effect of secondary metabolites of non-host plants on diamondback moth(dbm) plutella xylostella was studied, aimed at finding out the oviposition repellents and antifeedants of insect pests. when the ethanol extracts(etho exts) of bauhinia variegata, eucalyptus tereticornis, euphorbia hirta, duranta repens, zanthoxylum bungeanum, magnolia grandiflora, and nicotiana tabacum were applied resp ... | 2004 | 15228000 |
| screening of anti-helicobacter pylori herbs deriving from taiwanese folk medicinal plants. | in this study, extracts from 50 taiwanese folk medicinal plants were examined and screened for anti-helicobacter pylori activity. ninety-five percent ethanol was used for herbal extraction. paederia scandens (lour.) merr. (psm), plumbago zeylanica l. (pzl), anisomeles indica (l.) o. kuntze (aiok), bombax malabaricum dc. (bmdc) and alpinia speciosa (j. c. wendl.) k. schum. (asks) and bombax malabaricum dc. (bmdc) all demonstrated strong anti-h. pylori activities. the minimum inhibitory concentrat ... | 2005 | 15681161 |
| toxic effect of stem bark and leaf of euphorbia hirta plant against freshwater vector snail lymnaea acuminata. | the aqueous stem bark and leaf extracts of plant euphorbia hirta (family-euphorbiaceae) have potent molluscicidal activity. sub-lethal doses (40% and 80% of lc50) of aqueous stem bark and leaf extracts of this plant also significantly (p<0.05) alter the levels of total protein, total free amino acid, nucleic acids (dna and rna) and the activity of enzyme protease and acid and alkaline phosphatase in various tissues of the vector snail lymnaea acuminata in time and dose dependent manner. euphorbi ... | 2004 | 15722098 |
| [evaluation of non-host plant ethanol extracts against plutella xylostella population]. | through establishing experimental and natural population life tables, and by using the index of population trend (1) and interference index of population control (iipc), this paper evaluated 8 kinds of non-host plant ethanol extracts against experimental population of plutella xylostella, and 3 kinds of these extracts and their mixture against plutella xylostella natural population. the experimental population life table of dbm showed that the index of population trend (i) was 69. 8964 in contro ... | 2005 | 16180759 |
| effect of aqueous euphorbia hirta leaf extract on gastrointestinal motility. | the aqueous leaf extract of euphorbia hirta decreased the gastrointestinal motility in normal rats and decreased the effect of castor oil-induced diarrhoea in mice. | 2006 | 16257136 |
| inhibition of early and late phase allergic reactions by euphorbia hirta l. | a 95% ethanol extract from whole aerial parts of euphorbia hirta (eh a001) showed antihistaminic, antiinflammatory and immunosuppressive properties in various animal models. eh a001 inhibited rat peritoneal mast cell degranulation triggered by compound 48/80. it significantly inhibited dextran-induced rat paw edema. eh a001 prevented eosinophil accumulation and eosinophil peroxidase activity and reduced the protein content in bronchoalveolar lavage fluid (balf) in a 'mild' model of asthma. moreo ... | 2006 | 16557622 |
| antimicrobial activity of caesalpinia pulcherrima, euphorbia hirta and asystasia gangeticum. | the ethanolic extracts of the dry fruits of caesalpinia pulcherrima, aerial parts of euphorbia hirta and flowers of asystasia gangeticum were tested for antimicrobial activity. the three plants exhibited a broad spectrum of antimicrobial activity, particularly against escherichia coli (enteropathogen), proteus vulgaris, pseudomonas aeruginosa and staphylococcus aureus. | 2006 | 16730921 |
| comparative ultrastructural analyses of platelets and fibrin networks using the murine model of asthma. | the murine balb/c asthma model has been used successfully for a number of in vivo immunological applications and for testing novel therapeutics, and it is a reliable, clinically relevant facsimile of the human disease. here we investigate whether this model can be used to study other components of the human body, e.g. ultrastructure. in particular, we investigate the effect of the phytomedicine euphorbia hirta (used to treat asthma), on the ultrastructure of fibrin as well as platelets, cellular ... | 2007 | 17600694 |
| anti-anaphylactic effect of euphorbia hirta. | the euphorbia hirta ethanolic extract (eh a001) was found to possess a prominent anti-anaphylactic activity. a preventive effect of eh-a001 given by oral route at dose from 100 to 1000 mg/kg was observed against compound 48/80-induced systemic anaphylaxis. at the same range of dose, eh-a001 inhibited passive cutaneous anaphylaxis (pca) in rat and active paw anaphylaxis in mice. a suppressive effect of eh-a001 was observed on the release of tnf-alpha and il-6 from anti-dnp-hsa activated rat perit ... | 2007 | 17643865 |
| in vitro anti-helicobacter pylori activity of extracts of selected medicinal plants from north west cameroon. | helicobacter pylori, a gram negative microaerophilic bacterium is a major etiological agent in duodenal, peptic and gastric ulcers. the growing problem of antibiotic resistance by the organism demands the search for novel compounds from plant based sources. | 2007 | 17913416 |
| euphorbia hirta reverses chronic stress-induced anxiety and mediates its action through the gaba(a) receptor benzodiazepine receptor-cl(-) channel complex. | chronic stress is known to result in impairment of learning and memory and precipitate several affective disorders including depression and anxiety. drugs of natural origin are known to possess several effects on the central nervous system and are emerging as promising alternative therapies. in this context, the hydroalcoholic extract of euphorbia hirta (eh) was evaluated for anxiolytic property in chronically stressed rats subjected to elevated plus maze (epm) and open field test (oft). eh trea ... | 2008 | 18087670 |
| larvicidal activity of some euphorbiaceae plant extracts against aedes aegypti and culex quinquefasciatus (diptera: culicidae). | larvicidal activity of ethyl acetate, butanol, and petroleum ether extracts of five species of euphorbiaceae plants, jatropha curcas, pedilanthus tithymaloides, phyllanthus amarus, euphorbia hirta, and euphorbia tirucalli, were tested against the early fourth instar larvae of aedes aegypti l. and culex quinquefasciatus (say). the larval mortality was observed after 24 h of exposure. all extracts showed low larvicidal effects; however, the highest larval mortality was found in petroleum ether ext ... | 2008 | 18163189 |
| heavy metal accumulation in medicinal plants collected from environmentally different sites. | to estimate the heavy metal content in soil and selected medicinal plants procured from environmentally different sites of the same city. | 2008 | 18837296 |
| the effect of water extracts of euphorbia hirta on cartilage degeneration in arthritic rats. | the effect of water extracts of euphorbia hirta on the histological features and expressions of matrix metalloproteinases (mmps) and tissue inhibitors of matrix metalloproteinases (timps) in the rat articular cartilage was investigated. arthritis was induced in rats using freund's complete adjuvant containing heat-killed m. tuberculosis, and treated with water extracts of e. hirta. paraffin tissue sections of the arthritic joints were evaluated. the extent of cartilage degeneration was found to ... | 2008 | 19291918 |
| two novel butanol rhamnosides from an indian traditional herb, euphorbia hirta. | two novel butanol rhamnopyranosides (1 and 2), along with nine known compounds (3-11), have been isolated from various non-polar and polar extracts of an indian traditional herb, euphorbia hirta. the structures of the new compounds were elucidated as n-butyl-1-o-beta-l-rhamnopyranoside (1) and n-butyl-1-o-alpha-l-rhamnopyranoside (2) by spectroscopic methods including ir, hr-fabms, 1d and 2d nmr techniques. | 2009 | 19401919 |
| antiviral activities of extracts of euphorbia hirta l. against hiv-1, hiv-2 and sivmac251. | the antiretroviral activities of extracts of euphorbia hirta were investigated in vitro on the mt4 human t lymphocyte cell line. the cytotoxicities of the extracts were tested by means of the mtt cell proliferation assay, and then the direct effects of the aqueous extract on hiv-1, hiv-2 and siv(mac251) reverse transcriptase (rt) activity were determined. a dose-dependent inhibition of rt activity was observed for all three viruses. the hiv-1 inhibitory potency of e. hirta was studied further, a ... | 2009 | 19454510 |
| ability of certain plant extracts traditionally used to treat ciguatera fish poisoning to inhibit nitric oxide production in raw 264.7 macrophages. | ciguatera fish poisoning (cfp) is an intertropical ichthyosarcotoxism that manifests in complex assortment of symptoms in humans. ciguatoxins (ctxs), issued from gambierdicus spp., are causative agents of this intoxication. we have recently demonstrated that a pacific ctx (p-ctx-1b) strongly modulated inos expression, leading to overproduction of nitric oxide (no) in raw 264.7 murine macrophage cells. no produced in large amounts is involved in a wide range of pathophysiological processes. many ... | 2009 | 19501268 |
| mutagenic and antimutagenic activities of aqueous and methanol extracts of euphorbia hirta. | euphorbia hirta (e. hirta) is a weed commonly found in tropical countries and has been used traditionally for asthma, bronchitis and conjunctivitis. however, one of the constituents in this plant, quercetin, was previously reported to be mutagenic. this work aimed to determine the level of quercetin in the aqueous and methanol plant extracts and to investigate the mutagenic effects of quercetin and the extracts in the ames test utilising the mutant salmonella typhimurium ta98 and ta100 strains. ... | 2009 | 19778596 |
| amaranthus oleracea and euphorbia hirta: natural potential larvicidal agents against the urban indian malaria vector, anopheles stephensi liston (diptera: culicidae). | malaria control in developing countries is based largely on vector eradication by the use of mosquito larvicides which is an ideal method for controlling mosquito and the related epidemics. on account of ecohazardous nature, nontarget specificity of chemical insecticides and evidences of developing resistance against them in the exposed species, currently, importance of secondary plant metabolites has been acknowledged. insecticides of plant origin are environmentally safe, degradable, and targe ... | 2009 | 19838734 |
| molluscicides from some common medicinal plants of eastern uttar pradesh, india. | many aquatic snails act as intermediate hosts for the larvae of trematodes, fasciola hepatica and fasciola gigantica, which cause the diseases fascioliasis and schistosomiasis. the who has tested several thousands of synthetic compounds for the control of the snail host. although effective, these molluscicides have so far not proved themselves to be entirely satisfactory. with a growing awareness of environmental pollution, efforts are being made to discover molluscicidal products of plant origi ... | 2010 | 19943357 |
| a molecular pharmacology study into the anti-inflammatory actions of euphorbia hirta l. on the lps-induced raw 264.7 cells through selective inos protein inhibition. | euphorbia hirta l. has been widely used in india and chinese society. the molecular pharmacology basis of its anti-inflammatory effect is revealed in this work. the ethanol extract of euphorbia hirta l. (eh) and its active component were studied in lipopolysaccharide (lps)-activated macrophage cells (raw 264.7) as an established inflammation model. after activation, nitric oxide (no) production and expression of inos protein and inos mrna were measured by using a colorimetric assay (griess reage ... | 2010 | 20390370 |
| restoration of acetylcholinesterase activity by euphorbia hirta in discrete brain regions of chronically stressed rats. | several drugs of herbal origin are known to possess anxiolytic and antidepressant effects. in a recent study, we showed that extracts from euphorbia hirta l. (euphorbiaceae) (eh) demonstrated anxiolytic effects in rats subjected to chronic immobilization stress (cis) but not in rats that underwent forced swim stress (fss). acetylcholine and the cholinergic system are known to be involved in anxiety. however, whether the cholinergic system is involved in the anxiolytic actions of eh are not known ... | 2010 | 20645790 |
| which plant for which skin disease? part 2: dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. | this paper continues our review of scientifically evaluated plant extracts in dermatology. after plants effective against dermatophytes, botanicals with anti-edema effects in chronic venous insufficiency are discussed. there is good evidence from randomized clinical studies that plant extracts from grape vine leaves (vitis vinifera), horse chestnut (aesculus hippocastanum), sea pine (pinus maritima) and butcher's broom (ruscus aculeatus) can reduce edema in chronic venous insufficiency. plant ex ... | 2010 | 20707877 |
| in vitro activity of cameroonian and ghanaian medicinal plants on parasitic ( onchocerca ochengi) and free-living ( caenorhabditis elegans) nematodes. | ethanolic and aqueous extracts of selected medicinal plants from cameroon and ghana were assessed for their in vitro anthelmintic activity by using the bovine filarial parasite onchocerca ochengi and the free living nematode caenorhabditis elegans, a model organism for research on nematode parasites. worms were incubated in the presence of different concentrations of extracts and inhibitory effects were monitored at different time points. among the extracts used in this study, ethanolic extracts ... | 2010 | 20863422 |
| assessment of euphorbia hirta l. leaf, flower, stem and root extracts for their antibacterial and antifungal activity and brine shrimp lethality. | the antimicrobial activities of the methanolic extracts of euphorbia hirta l leaves, flowers, stems and roots were evaluated against some medically important bacteria and yeast using the agar disc diffusion method. four gram positive (staphylococcus aureus, micrococcus sp., bacillus subtilis and bacillus thuringensis), four gram negative (escherichia coli, klebsiella pneumonia, salmonella typhi and p. mirabilis) and one yeast (candida albicans) species were screened. inhibition zones ranged betw ... | 2010 | 20877206 |
| traditional herbal medicine in far-west nepal: a pharmacological appraisal. | plant species have long been used as principal ingredients of traditional medicine in far-west nepal. the medicinal plants with ethnomedicinal values are currently being screened for their therapeutic potential but their data and information are inadequately compared and analyzed with the ayurveda and the phytochemical findings. | 2010 | 21144003 |
| antidiabetic and free radicals scavenging potential of euphorbia hirta flower extract. | the present study was carried out to evaluate antidiabetic and in vitro free radicals scavenging effects of flower extract of euphorbia hirta. the ethanolic and petroleum ether extracts (250 and 500 mg/kg) were orally tested for 21 days in alloxan induced diabetic mice and blood glucose level was measured with glucometer. administration of extract resulted in significant reduction in serum cholesterol, triglycerides, creatinine, urea, alkaline phosphatase levels but high density lipoprotein leve ... | 2010 | 21218075 |
| a review of traditional remedies of ciguatera fish poisoning in the pacific. | ciguatera fish poisoning (cfp) is an illness caused by eating tropical coral fish contaminated with ciguatoxins (ctxs). the clinical management of patients with cfp is generally supportive and symptomatic in nature as no antidote exists. of the many drugs prescribed, several have been claimed to be efficient in small, uncontrolled studies, but the outcomes of treatments with these medicines are often contradictory. in new caledonia, traditional remedies are commonly employed in the treatment of ... | 2011 | 21287650 |
| protective potential [correction of potencial] of euphorbia hirta against cytotoxicity induced in hepatocytes and a hepg2 cell line. | medicinal plants play a key role in human health care. frustration over the side effects of allopathic drugs has driven the medical world to take asylum in the plant kingdom for the treatment of various ailments. euphorbia hirta belonging to the family of euphorbiacae has been reported to possess antibacterial, antiviral, and anticancer activity. the aim of the present study was to investigate the protective effect of e. hirta against antitubercular drug-induced cytotoxicity in freshly isolated ... | 2010 | 21305854 |
| specific and nonspecific immunostimulation study of euphorbia hirta on pseudomonas fluorescens-infected cyprinus carpio. | infectious diseases are one of the major factors affecting the production of fish worldwide. the pathogens (especially bacteria) affect the immune system of fish and the administration of immunostimulants can increase resistance to infectious diseases by enhancing both specific and nonspecific defense mechanisms. | 2011 | 21385104 |
| efficacy of euphorbia hirta latex as plant derived molluscicides against freshwater snails. | the toxic effect of binary and tertiary combinations of euphorbia hirta linn latex powder with other plant molluscicidal compounds, were evaluated against the freshwater snails lymnaea (radix) acuminata and indoplanorbis exustus in pond. these combinations showed significant time and dose dependent effect against both the snails. these compounds at higher doses were also lethal to freshwater fish channa punctatus (bloch) (channidae {ophicephalidae}), which shares the habitat with these snails, b ... | 2011 | 21537758 |
| antioxidant activity and phytochemical screening of the methanol extracts of euphorbia hirta l. | to assess antioxidant activities of different parts of euphorbia hirta (e. hirta), and to search for new sources of safe and inexpensive antioxidants. | 2011 | 21771682 |
| antibacterial activity of selected ethnomedicinal plants from south india. | to screen the antimicrobial potential of three ethnomedicinal plants chassalia curviflora thw. (c. curviflora), cyclea peltata hook. f. & thomson (c. peltata) and euphorbia hirta l (e. hirta) used in folk medicines in aarukani hills kani tribe, tamil nadu, india against human bacterial pathogens. | 2011 | 21771680 |
| toxic effect of two common euphorbiales latices on the freshwater snail lymnaea acuminata. | the aqueous and serially purified latex extracts of plants euphorbia pulcherima and euphorbia hirta (family euphorbiaceae) have potent molluscicidal activity. sub-lethal doses (40 and 80% of lc(50)) of aqueous and partially purified latex extracts of both the plants also significantly alter the levels of total protein, total free amino acid, nucleic acid (dna and rna) and the activity of enzyme protease and acid and alkaline phosphatase in nervous tissue of the snail lymnaea acuminata in time an ... | 2004 | 21782684 |
| evaluation of medicinal plant extracts and isolated compound epicatechin from ricinus communis against paramphistomum cervi. | the purpose of this study is to determine the efficacies of hexane, chloroform, ethyl acetate, acetone, and methanol leaf extracts of euphorbia hirta l., psidium guajava l., ricinus communis l., solanum trilobatum l., and tridax procumbens l. against sheep fluke paramphistomum cervi (digenea: paramphistomatidae). all plant extracts showed moderate effects after 24-áh of exposure; however, the highest parasite mortality was found in the methanol extract of r. communis. in the present study, bioas ... | 2011 | 21842382 |
| assessment of immunomodulatory activity of euphorbia hirta l. | immune system is the major target for development of treatment strategies to improve the management of infections. many species of indian medicinal plants have been reported to possess active principles with immunomodulating properties. euphorbia hirta, a pantropic herb has been reported to be pharmacologically active. this study reports one another not widely reported property of the plant, immunomodulatory activity, which has been proved using simple techniques like the macrophage activity tes ... | 2010 | 21694995 |
| antidiabetic and antioxidant potentials of euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats. | euphorbia hirta, commonly known as asthma weed, is a popular folk remedy for the treatment of various ailments. recent studies have indicated that plant has potent antioxidant properties. as part of an ongoing programme to validate the use of some reputed herbs in indian traditional medicines, the present study was aimed to evaluate the antidiabetic and antioxidant potentials of e. hirta leaves in streptozotocin-induced experimental diabetes in rats. oral administration of e. hirta leaves extrac ... | 2011 | 21952437 |
| evaluation of enzymes inhibition activities of medicinal plant from burkina faso. | the aim of the present study was to evaluate some enzymes inhibitory effects of 11 plant species belonging to 9 families from burkina faso. methanolic extracts were used for their glutathione-s-transferase (gst), acetylcholinesterase (ache), carboxylesterase (ces) and xanthine oxidase (xo) inhibitory activities at final concentration of 100 microg ml(-1). the total phenolics, flavonoids and tannins were also determined spectrophotometrically using folin-ciocalteu, alcl3 and ammonium citrate iron ... | 2011 | 21916259 |
| Antibacterial activity of selected medicinal plants against multiple antibiotic resistant uropathogens: a study from Kolli Hills, Tamil Nadu, India. | The increasing incidence of antibiotic resistance among bacterial pathogens necessitates medicinal plants as an alternate therapy in restricting the resistant infectious organisms. In this primitive study, the antibiotic resistance of organisms isolated from urinary tract infected patients was evaluated using the National Committee for Clinical Laboratory Standards (NCCLS) method and Multiple Antibiotic Resistance (MAR) index values, and the MAR values was also calculated for plant extracts. The ... | 2011 | 21986363 |
| amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb euphorbia hirta. | euphorbia hirta (l.) (euphorbiaceae) is a very popular herb amongst practitioners of traditional medicine and used in the treatment of female disorders, respiratory ailments, tumors, jaundice, digestive problems, wounds, etc. we aimed to evaluate the protective effect of e. hirta against nitrobenzene-induced nephrotoxicity in albino rats. | 2011 | 22022170 |
| euphorbia hirta: its chemistry, traditional and medicinal uses, and pharmacological activities. | the oldest remedies known to mankind are herbal medicines. india is known worldwide for its ayurvedic treatment. euphorbia hirta is often used traditionally for female disorders, respiratory ailments (cough, coryza, bronchitis, and asthma), worm infestations in children, dysentery, jaundice, pimples, gonorrhea, digestive problems, and tumors. it is reported to contain alkanes, triterpenes, phytosterols, tannins, polyphenols, and flavanoids. this review describes the medicinal properties, chemica ... | 2010 | 22228942 |
| purification and physicochemical characterization of a serine protease with fibrinolytic activity from latex of a medicinal herb euphorbia hirta. | a 34 kda serine protease, designated as hirtin, with fibrinolytic activity was purified to homogeneity from the latex of euphorbia hirta by the combination of ion exchange and gel filtration chromatography. the n-terminal sequence of hirtin was found to be yavyigliletaa/nne. hirtin exhibited esterase and amidase activities along with azocaseinolytic, gelatinolytic, fibrinogenolytic and fibrinolytic activities. it preferentially hydrolyzed aα and α-chains, followed by bβ and β, and γ and γ-γ chai ... | 2011 | 22305073 |
| a transmission electron microscopy study of the diversity of candida albicans cells induced by euphorbia hirta l. leaf extract in vitro. | to determine the major changes in the microstructure of candida albicans (c. albicans) after treatment with euphorbia hirta (e. hirta) l. leaf extract. | 2011 | 23569719 |
| phenols and flavonoids from the aerial part of euphorbia hirta. | to investigate the chemical constituents of the aerial part of euphorbia hirta linn. | 2012 | 23302529 |
| effect of euphorbia hirta plant leaf extract on immunostimulant response of aeromonas hydrophila infected cyprinus carpio. | the main objective of the present study is to improve the immune power of cyprinus carpio by using euphorbia hirta plant leaf extract as immunostimulants. the haematological, immunological and enzymatic studies were conducted on the medicated fish infected with aeromonas hydrophila pathogen. the results obtained from the haematological studies show that the rbc count, wbc count and haemoglobin content were increased in the infected fish at higher concentration of leaf extract. the feeds with lea ... | 2014 | 25405077 |
| phytochemical study and screening for antimicrobial activity of flavonoids of euphorbia hirta. | this study aims to phytochemical and antimicrobial study of euphorbia hirta euphorbiaceae). | 2013 | 24083146 |
| triterpenes from euphorbia hirta and their cytotoxicity. | to investigate the chemical constituents of the stems, leaves and roots of euphorbia hirta, and to test for the cytotoxic and antimicrobial potentials of the major constituents of the plant. | 2013 | 24359779 |
| euphorbia hirta accelerates fibroblast proliferation and smad-mediated collagen production in rat excision wound. | euphorbia hirta l. (euphorbiaceae) is a traditional herbal medicine used for treatment of various diseases. | 2014 | 25298671 |
| antibiogram and gc analysis of euphorbia hirta leaf extract. | the antibiogram activity of ethanolic and aqueous extract of e.hirta was studied. ethanol extract of the plant showed the maximal antibacterial activity and g.c analysis showed the presence of citronellal. the extract showed inhibited the growth of e.coli, s.aureus, p.aeruginosa, proteus etc.. | 2007 | 22557242 |
| mosquito larvicidal and pupicidal activity of euphorbia hirta linn. (family: euphorbiaceae) and bacillus sphaericus against anopheles stephensi liston. (diptera: culicidae). | to explore the larvicidal and pupicidal activity of euphorbia hirta (e. hirta) leaf extract and bacillus sphaericus (b. sphaericus) against the malarial vector, anopheles stephensi (an. stephensi). | 2013 | 23339910 |
| extracts of euphorbia hirta linn. (euphorbiaceae) and rauvolfia vomitoria afzel (apocynaceae) demonstrate activities against onchocerca volvulus microfilariae in vitro. | onchocerciasis transmitted by onchocerca volvulus is the second major cause of blindness in the world and it impacts negatively on the socio-economic development of the communities affected. currently, ivermectin, a microfilaricidal drug is the only drug recommended for treating this disease. there have been speculations, of late, concerning o. volvulus resistance to ivermectin. owing to this, it has become imperative to search for new drugs. world-wide, ethnomedicines including extracts of euph ... | 2013 | 23506674 |
| evaluation of antiplasmodial activity of medicinal plants from north indian buchpora and south indian eastern ghats. | development of resistance against the frontline anti-malarial drugs has created an alarming situation, which requires intensive drug discovery to develop new, more effective, affordable and accessible anti-malarial agents. | 2015 | 25879738 |
| biomimetic synthesis of silver nanoparticles using endosymbiotic bacterium inhabiting euphorbia hirta l. and their bactericidal potential. | the present investigation aims to evaluate biomimetic synthesis of silver nanoparticles using endophytic bacterium eh 419 inhabiting euphorbia hirta l. the synthesized nanoparticles were initially confirmed with change in color from the reaction mixture to brown indicating the synthesis of nanoparticles. further confirmation was achieved with the characteristic absorption peak at 440 nm using uv-visible spectroscopy. the synthesized silver nanoparticles were subjected to biophysical characteriza ... | 2016 | 27403378 |
| anti-infective potential of caffeic acid and epicatechin 3-gallate isolated from methanol extract of euphorbia hirta (l.) against pseudomonas aeruginosa. | euphorbia hirta (l.) plant is traditionally used in malaysia for the treatment of gastrointestinal, bronchial and respiratory ailments caused by nosocomial infectious agents. bioactivity-guided fractionation of the methanol extract of the aerial parts of e. hirta and analysis using high-performance liquid chromatography have led to the isolation of two antibacterial compounds. these compounds were identified as caffeic acid (ca) and (-)-epicatechin 3-gallate (ecg) based on spectroscopic analyses ... | 2015 | 25571920 |
| chemical analysis, inhibition of biofilm formation and biofilm eradication potential of euphorbia hirta l. against clinical isolates and standard strains. | the frequent occurrences of antibiotic-resistant biofilm forming pathogens have become global issue since various measures that had been taken to curb the situation led to failure. euphorbia hirta, is a well-known ethnomedicinal plant of malaysia with diverse biological activities. this plant has been used widely in traditional medicine for the treatment of gastrointestinal, bronchial and respiratory ailments caused by infectious agents. | 2013 | 24321370 |
| effects of some dietary crude plant extracts on the growth and gonadal maturity of nile tilapia (oreochromis niloticus) and their resistance to streptococcus agalactiae infection. | a 90-day feeding trial was conducted on the growth performance, feeding efficacy, body indices, various hematological and plasma biochemical parameters, and histopathological examination of the gonads from male and female nile tilapia fingerlings when fed different crude plant extracts from cinnamomum camphora, euphorbia hirta, azadirachta indica, or carica papaya at 2 g kg(-1) compared to a control diet. this was followed by a 14-day challenge to streptococcus agalactiae. all treatments were tr ... | 2016 | 26643907 |
| plant-based medicines for anxiety disorders, part 1: a review of preclinical studies. | research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. however, a comprehensive review of plant-based anxiolytics has been absent to date. this article (part 1) reviews herbal medicines for which only preclinical investigations for anxiolytic activity have been performed. in part 2, we review herbal medicines for which there have been clinical investigations for a ... | 2013 | 23436255 |
| ethnomedicinal plants used by the villagers of district udhampur, j&k, india. | plants are an integral part of life in many indigenous communities. besides, being the source of food, fodder, fuel, etc., the use of plants as herbal medicines in curing several ailments goes parallel to the human civilization. ethnopharmacology involves the investigation of the plants used by the traditional communities and further understand the pharmacological basis of these culturally important medicinal plants. present study was conducted to enlist the medicinal plants used by the local in ... | 2014 | 24365639 |
| genotoxicity of euphorbia hirta: an allium cepa assay. | the potential genotoxic effects of methanolic extracts of euphorbia hirta which is commonly used in traditional medicine to treat a variety of diseased conditions including asthma, coughs, diarrhea and dysentery was investigated using allium cepa assay. the extracts of 125, 250, 500 and 1,000 µg/ml were tested on root meristems of a. cepa. ethylmethanesulfonate was used as positive control and distilled water was used as negative control. the result showed that mitotic index decreased as the con ... | 2012 | 22735780 |
| air-borne contact dermatitis in varanasi. | forty-six patients suspected to have air borne contact dermatitis were tested with various plant antigens. thirteen patients turned out to be sensitive to one or more antigens. the plant antigens, used for testing, were parthenium hysterophorus, lantana camara, cynodon dactylon, bougainvaled spectabills, calotropis procera, argimone mexicana, acacia arabica, azadiracha indica, eucalyptus rostrata, saraka indica, triticum vulgare, triticum aestivum, dryopteris filix, nerium indicum, eclipta alba, ... | 2017 | 28150592 |
| contact dermatitis due to plants. | forty-seven cases of suspected plant dermatitis were patch tested with extracts of various plants. twenty-six showed positive patch tests to one or more plant antigens. parthenium sensitivity was observed in nine cases. trianthema monogyna, carissa, carandus, amaranthus viridis, amaranthus spinosus, euphorbia hirta, euphorbia thymibolia, salvia plebia, lantana camera and pennisetum typhoides were other important plants founds to be responsible for contact sensitivity. majority of the patients we ... | 2017 | 28193929 |
| adulticidal, repellent, and ovicidal properties of indigenous plant extracts against the malarial vector, anopheles stephensi (diptera: culicidae). | mosquito-borne diseases with an economic impact create loss in commercial and labor outputs, particularly in countries with tropical and subtropical climates. mosquito control is facing a threat because of the emergence of resistance to synthetic insecticides. extracts from plants may be alternative sources of mosquito control agents because they constitute a rich source of bioactive compounds that are biodegradable into nontoxic products and potentially suitable for use to control mosquitoes. i ... | 2013 | 23192528 |
| biolarvicidal and pupicidal potential of silver nanoparticles synthesized using euphorbia hirta against anopheles stephensi liston (diptera: culicidae). | vector control is a critical requirement in epidemic disease situations, as is an urgent need to develop new and improved mosquito control methods that are economical and effective yet safe for nontarget organisms and the environment. mosquitoes transmit serious human diseases, causing millions of deaths every year. use of synthetic insecticides to control vector mosquitoes has caused physiological resistance and adverse environmental effects in addition to high operational cost. insecticides of ... | 2012 | 22562234 |
| ethnopharmacological studies on the uses of euphorbia hirta in the treatment of dengue in selected indigenous communities in pangasinan (philippines). | euphorbia hirta is the most widely used plant in the folkloric treatment of dengue in the philippines. this study documents the anecdotal uses of e. hirta in the treatment of dengue in 3 indigenous communities in pangasinan from april to june of 2015. | 2017 | 27366349 |
| traditional knowledge on poisonous plants of udhampur district of jammu and kashmir, india. | poisonous plants comprise the third largest category of poisons known around the world. other than affecting the humans directly, they are the major cause of economic losses in the livestock industry since the advent of civilisation. aim of the present study was to collect and systematically document the traditional knowledge of poisonous plants of udhampur district for the benefit of humanity before it is entombed forever. | 2014 | 24412380 |
| plants used for treatment of dysentery and diarrhoea by the bhoxa community of district dehradun, uttarakhand, india. | dysentery and diarrhoea are major causes of morbidity and mortality in rural communities of developing world. the bhoxa community is an important primitive indigenous community of uttarakhand, india. in this paper we have tried to scientifically enumerate ethnomedicinal plants and herbal preparations used by bhoxa community to treat dysentery and diarrhoea, and discuss their antidiarrhoeal properties in the light of previous ethnomedicinal, pharmacological, microbiological and phytochemical stud ... | 2013 | 24513640 |
| plants used for treatment of dysentery and diarrhoea by the bhoxa community of district dehradun, uttarakhand, india. | dysentery and diarrhoea are major causes of morbidity and mortality in rural communities of developing world. the bhoxa community is an important primitive indigenous community of uttarakhand, india. in this paper we have tried to scientifically enumerate ethnomedicinal plants and herbal preparations used by bhoxa community to treat dysentery and diarrhoea, and discuss their antidiarrhoeal properties in the light of previous ethnomedicinal, pharmacological, microbiological and phytochemical stud ... | 2013 | 24432368 |
| toxicity and physiological effect of quercetin on generalist herbivore, spodoptera litura fab. and a non-target earthworm eisenia fetida savigny. | a novel flavonoid, quercetin, was isolated from the medicinal plant euphorbia hirta l. through chromatography techniques including: tlc, column chromatography, nmr and then screened for toxicity to larvae of spodoptera litura fab. bioassays were used to analyze pupal weight, survival rate, fecundity, egg hatchability, population growth index, nutritional index and histopathology of treated larvae at a range of e. hirta extract concentrations. results of toxicity assays demonstrated that, 6 ppm o ... | 2016 | 27657818 |
| prophylactic and curative anti-ulcerogenic activity and the possible mechanisms of action of some desert plants. | the present study aimed to evaluate the anti-ulcerogenic activities and the possible mechanisms of action of seven desert plants from different families. conyza dioscoridis (l.) desf. (asteraceae), euphorbia hirta l. (euphorpiaceae), origanum syriacum l., salvia lanigera l. (lamiaceae), sisymbrium irio l., solanum nigrum linn. (solanaceae) and solenostemma arghel (del.) hayne. (asclepiadaceae), were tested using prophylactic and curative models of absolute ethanol-induced ulcer, at three doses ( ... | 2017 | 28344494 |
| unraveling the karyotype structure of the spurges euphorbia hirta linnaeus, 1753 and e. hyssopifolia linnaeus, 1753 (euphorbiaceae) using genome size estimation and heterochromatin differentiation. | euphorbia linnaeus, 1753 (euphorbiaceae) is one of the most diverse and complex genera among the angiosperms, showing a huge diversity in morphologic traits and ecologic patterns. in order to improve the knowledge of the karyotype organization of euphorbia hirta (2n = 18) and euphorbia hyssopifolia (2n = 12), cytogenetic studies were performed by means of conventional staining with giemsa, genome size estimations with flow cytometry, heterochromatin differentiation with chromomycin a3 (cma) and ... | 2016 | 28123686 |
| photoinduced green synthesis of silver nanoparticles with highly effective antibacterial and hydrogen peroxide sensing properties. | in this study, an eco-friendly and sustainable green route was employed for the synthesis of stable silver nanoparticles (agnps) using aqueous leaf extract of euphorbia hirta (aee) as both reducing as well as a stabilizing agent. the synthesis of agnps was confirmed by uv-visible spectroscopy which produced a prominent spr band at λmax 425nm after 25min of sunlight exposure. the agnps thus synthesized were optimized using one factor at a time approach, and these optimized conditions were 25min o ... | 2016 | 27424098 |
| ethnobotanical study of latex plants in the maritime region of togo. | in togo, a little is known about latex plants of the flora used for medicinal purposes. | 2017 | 27034604 |
| quercetin-3-o-rhamnoside from euphorbia hirta protects against snake venom induced toxicity. | the plant euphorbia hirta is widely used against snake envenomations in rural areas and it was proved to be effective in animal models. therefore, the scientific validation of its phytoconstituents for their antiophidian activity is aimed in the present study. | 2016 | 27033089 |
| inhibition of α-glucosidase by new prenylated flavonoids from euphorbia hirta l. herb. | euphorbia hirta l. (euphorbiaceae) is a pantropical medicinal rhizomatous herb, traditionally used in the treatment of diabetes, respiratory and gastro-intestinal disorders. | 2015 | 26477374 |
| evaluation of the cytotoxicity, cell-cycle arrest, and apoptotic induction by euphorbia hirta in mcf-7 breast cancer cells. | euphorbia hirta l. (euphorbiaceae) has been used as a folk remedy in southeast asia for the treatment of various ailments. | 2016 | 26154521 |
| protective effect of euphorbia hirta and its components against snake venom induced lethality. | despite the use of snake anti-venom therapy, herbal medicine is still in practice to treat snakebites. euphorbia hirta is traditionally used as antidote for snakebites and also for numerous other ailments. however, the scientific evidence for its anti-snake venom property is still lacking. | 2015 | 25727964 |
| in vitro anti-inflammatory activity of fractionated euphorbia hirta aqueous extract on rabbit synovial fibroblasts. | euphorbia hirta has been reported to possess anti-inflammatory activity. this study was carried out to determine the prostaglandin e 2 (pge 2 ) inhibition activity of the fractions of the e. hirta aqueous extract on rabbit synovial fibroblast cells (hig-82). | 2016 | 25673170 |
| minerals salt composition and secondary metabolites of euphorbia hirta linn., an antihyperglycemic plant. | phytochemical study and research on acute toxicity were performed on the aerial parts (leaves and stems) of euphorbia hirta linn. the phytochemical screening and chromatography revealed the presence of saponin, sterol, terpene, alkaloids, polyphenols, tannins and flavonoids and especially mucilage. the evaluation of total polyphenols and total flavonoids gave 120.97 ± 7.07 gallic acid equivalents (gae) mg/g (mg of gae/g of extract) of dry extract and 41.4 ± 0.5 mg quercetin equivalent per gram ( ... | 2017 | 25598628 |
| evaluation of the antioxidant, anti-inflammatory, and anticancer activities of euphorbia hirta ethanolic extract. | this study evaluated the chemical composition, antioxidant, anti-inflammatory and anticancer activities of a euphorbia hirta l. extract. the antioxidant activities of whole e. hirta ethanol extract were determined by electron spin resonance spectrophotometric analysis of 1,1-diphenyl-2-picryl-hydrazyl (dpph), hydroxyl, and alkyl radical levels and by using an online high-performance liquid chromatography (hplc)-2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assay. the e. hirta ethanol ex ... | 2014 | 25225720 |