Publications

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antifilarial activity of mallotus philippensis lam. on setaria cervie (nematoda: filarioidea) in vitro.the effect of aqueous and alcoholic extracts of the leaves of mallotus philippensis (lam.) muell. arg. was studied on the spontaneous movements of the whole worm and nerve-muscle (n.m.) preparation of setaria cervi and on the survival of microfilariae in vitro. both the extracts caused inhibition of spontaneous motility of whole worm and the n.m. preparation of s. cervi characterized by initial stimulation followed by depression in amplitude. the tone and rate of contractions remained visibly un ...199710235663
potential anti-tumor-promoting activity of 3alpha-hydroxy-d:a-friedooleanan-2-one from the stem bark of mallotus philippensis.four known friedelane-type triterpenoids, friedelin ( 1), 3-hydroxy-d:a-friedoolean-3-en-2-one ( 2), 2beta-hydroxy-d:a-friedooleanan-3-one ( 3), and 3alpha-hydroxy-d:a-friedooleanan-2-one ( 4), and two known lupane-type triterpenoids, lupeol ( 5) and betulin ( 6), were isolated from the stem bark of mallotus philippensis. isolates 1 - 4 and their synthetic analogues, 3-acetoxy-d:a-friedoolean-3-en-2-one ( 2a) and 3alpha-acetoxy-d:a-friedooleanan-2-one ( 4a), were tested for their inhibitory effe ...200818484534
detection of anti-tuberculosis activity in some folklore plants by radiometric bactec assay.the anti-tubercular drugs are less effective because of the emergence of multi-drug resistant (mdr) and extensively drug resistant (xdr) strains of m. tuberculosis, so plants being an alternative source of anti-microbial compounds. the aim of this study was to investigate anti-tuberculosis potential of the plants using mycobacterium smegmatis as a rapid screening model for detection of anti-mycobacterial activity and further to evaluate the active plants for anti-tuberculosis activity against m. ...201021114505
feeding preferences of the asian elephant (elephas maximus) in nepal.nepal provides habitat for approximately 100-125 wild asian elephants (elephas maximus). although a small proportion of the world population of this species, this group is important for maintaining the genetic diversity of elephants and conservation of biodiversity in this region. knowledge of foraging patterns of these animals, which is important for understanding their habitat requirements and for assessing their habitat condition, is lacking for the main areas populated by elephants in nepal. ...201627855704
anti-allergic agents from natural sources (4): anti-allergic activity of new phloroglucinol derivatives from mallotus philippensis (euphorbiaceae).two new phloroglucinol derivatives, mallotophilippen a (1). and b (2). were isolated from the fruits of mallotus philippensis. these compounds were identified, using chemical and spectral data, as 1-[5,7-dihydroxy-2,2-dimethyl-6-(2,4,6-trihydroxy-3-isobutyryl-5-methyl-benzyl)-2h-chromen-8-yl]-2-methyl-butan-1-one and 1-[6-(3-acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2h-chromen-8-yl]-2-methyl-butan-1-one, respectively. they inhibited nitric oxide (no) production and indu ...200212499591
effect of feeding different levels of wheat roti on nutrient utilization and blood metabolite profile in semi-captive asian elephants (elephas maximus).this experiment was conducted to study the effect of different levels of wheat roti (wr) on nutrient utilization and blood metabolites in asian elephants fed roughages ad libitum. nine (3 m, 6 f) asian elephants (14-52 years of age, 1909-3968 kg bw) were used in an experiment based on replicated latin square design. animals in each group (n = 3) were assigned to one of the three dietary treatments in a manner that animals in all the three groups were exposed to all the three treatments in three ...201524821439
antioxidant and antiplasmodial activities of bergenin and 11-o-galloylbergenin isolated from mallotus philippensis.two important biologically active compounds were isolated from mallotus philippensis. the isolated compounds were characterized using spectroanalytical techniques and found to be bergenin (1) and 11-o-galloylbergenin (2). the in vitro antioxidant and antiplasmodial activities of the isolated compounds were determined. for the antioxidant potential, three standard analytical protocols, namely, dpph radical scavenging activity (rsa), reducing power assay (rpa), and total antioxidant capacity (tac) ...201626998192
novel r-plasmid conjugal transfer inhibitory and antibacterial activities of phenolic compounds from mallotus philippensis (lam.) mull. arg.antimicrobial resistance severely limits the therapeutic options for many clinically important bacteria. in gram-negative bacteria, multidrug resistance is commonly facilitated by plasmids that have the ability to accumulate and transfer refractory genes amongst bacterial populations. the aim of this study was to isolate and identify bioactive compounds from the medicinal plant mallotus philippensis (lam.) mull. arg. with both direct antibacterial properties and the capacity to inhibit plasmid c ...201627436460
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