| development of probiotic cheese manufactured from goat milk: response surface analysis via technological manipulation. | production of caprine milk has been rising steadily, partially because of its good nutritional value; the possibility of improving nutritional benefits by adding probiotic species such as bifidobacterium lactis and lactobacillus acidophilus was assessed. the manufacturing process of a traditional semi-hard goat cheese was technologically modified to optimize the process. the amount of starter inoculum, the concentration of salt, the addition of a protein hydrolysate, and the ripening time were v ... | 1998 | 9684158 |
| the ability of probiotic bacteria to bind to human intestinal mucus. | human mucus was isolated from faecal samples of newborns, two and six month old infants and adults. the adhesion to this mucus by the bacteria mentioned below was assessed in vitro. depending on the age group: 44-46% of the applied lactobacillus gg, 23-30% of bifidobacterium lactis bb-12, 9-14% of lactobacillus johnsonii lj-1, 3-10% of lactobacillus salivarius lm2-118, lactobacillus crispatus m247, lactobacillus paracasei f19 and 2% of l. crispatus mu5 adhered. all the strains adhered better to ... | 1998 | 9809419 |
| use of small ruminants' milk supplemented with available nitrogen as growth media for bifidobacterium lactis and lactobacillus acidophilus. | growth of, and acid production by bifidobacterium lactis and lactobacillus acidophilus using ovine and caprine milk as media were evaluated for their potential use in cheese-making. a protein hydrolysate (mhp, obtained from incubation of bovine milk with protease) or a mixture of free amino acids (faa, similar to the amino acid fraction of mhp) was added as a nitrogen enrichment source. bifidobacterium lactis and lact. acidophilus were inoculated at 50 ml l-1 and incubated at 37 degrees c with g ... | 1998 | 9830119 |
| growth enhancement of bifidobacterium lactis bo and lactobacillus acidophilus ki by milk hydrolyzates. | the determination of the best conditions of preparation of a (tentatively) probiotic starter culture that might be suitable for cheese making composed solely of bifidobacterium lactis bo and lactobacillus acidophilus ki is critical if a consistently reliable acid production is to be achieved, especially because bifidobacteria have stringent requirements for growth. therefore, we determined whether b. lactis bo and l. acidophilus ki required or benefitted from the addition of milk hydrolyzates (b ... | 1998 | 9839223 |
| use of modified lactobacillus selective medium and bifidobacterium iodoacetate medium for differential enumeration of lactobacillus acidophilus and bifidobacterium spp. in powdered nutritional products. | modified lactobacillus selective agar (apt agar + sodium acetate and glacial acetic acid; mlbs) was compared to selective modified lactobacillus selective medium (lbs agar + tomato juice and acetic acid; mlsm) and nonselective de man rogosa sharpe (mrs) agar for the enumeration of lactobacillus acidophilus in probiotic-containing powdered nutritional products. the mlbs agar was equivalent to mrs agar and superior to the mlsm agar for enumerating l. acidophilus in products stored in sealed cans a ... | 1999 | 9921834 |
| antiproliferative effects of homogenates derived from five strains of candidate probiotic bacteria. | unheated and heat-treated homogenates were separately prepared from candidate probiotic bacteria, including lactobacillus rhamnosus gg, bifidobacterium lactis, lactobacillus acidophilus, lactobacillus delbrueckii subsp. bulgaricus, and streptococcus thermophilus. we compared the phytohemagglutinin-induced proliferation of mononuclear cells in the presence of homogenates and in the presence of a control containing no homogenate by assessing thymidine incorporation in cell cultures. all homogenate ... | 1999 | 10543777 |
| enhancement of natural immune function by dietary consumption of bifidobacterium lactis (hn019). | to determine the effects of dietary consumption of bifidobacterium lactis (strain hn019, dr10tm) on natural immunity. | 2000 | 10713750 |
| acute oral toxicity and bacterial translocation studies on potentially probiotic strains of lactic acid bacteria. | three potentially probiotic lactic acid bacteria (lab) strains, lactobacillus rhamnosus hn001 (dr20(tm)), lb. acidophilus hn017 and bifidobacterium lactis hn019 (dr10()), have recently been identified and characterized. the present study was designed to evaluate the acute oral toxicity of these strains to mice, and also to investigate bacterial translocation and gut mucosal pathology in balb/c mice fed hn019, hn001 or hn017 for 8 consecutive days at a high dose of 10(11)cfu/mouse/day. results sh ... | 2000 | 10717355 |
| the mucus binding of bifidobacterium lactis bb12 is enhanced in the presence of lactobacillus gg and lact. delbrueckii subsp. bulgaricus. | the ability to adhere to mucosal surfaces is related to many probiotic health effects. in the presence of lactobacillus gg or lact. bulgaricus, the adhesion of bifidobacterium lactis bb12 to a mucus model was more than doubled. other tested lactobacilli did not affect the adhesion, nor was the adhesion of the lactobacilli influenced by the bifidobacteria. co-aggregation between bif. lactis bb12 and the tested lactobacilli was insignificant and does not explain the observed effect. the results su ... | 2000 | 10728552 |
| enhancement of natural and acquired immunity by lactobacillus rhamnosus (hn001), lactobacillus acidophilus (hn017) and bifidobacterium lactis (hn019). | consumption of lactic acid bacteria (lab) has been suggested to confer a range of health benefits including stimulation of the immune system and increased resistance to malignancy and infectious illness. in the present study, the effects of feeding lactobacillus rhamnosus (hn001, dr20), lactobacillus acidophilus (hn017) and bifidobacterium lactis (hn019, dr10) on in vivo and in vitro indices of natural and acquired immunity in healthy mice were examined. mice were fed daily with l. rhamnosus, l. ... | 2000 | 10743496 |
| dietary bifidobacterium lactis (hn019) enhances resistance to oral salmonella typhimurium infection in mice. | the ability of a newly identified probiotic lactic acid bacterial strain, bifidobacterium lactis (hn019), to confer protection against salmonella typhimurium was investigated in balb/c mice. feeding mice with b. lactis conferred a significant degree of protection against single or multiple oral challenge with virulent s. typhimurium, in comparison to control mice that did not receive b. lactis. protection included a ten-fold increase in survival rate, significantly higher post-challenge food int ... | 2000 | 10832963 |
| safety assessment of potential probiotic lactic acid bacterial strains lactobacillus rhamnosus hn001, lb. acidophilus hn017, and bifidobacterium lactis hn019 in balb/c mice. | the general safety of immune-enhancing lactic acid bacteria (lab) strains lactobacillus rhamnosus hn001 (dr20), lb. acidophilus hn017, and bifidobacterium lactis hn019 (dr10) was investigated in a feeding trial. groups of balb/c mice were orally administered test lab strains or the commercial reference strain lb. acidophilus la-1 at 2.5 x 10(9), 5 x 10(10) or 2.5 x 10(12) colony forming units (cfu)/kg body weight/day for 4 weeks. throughout this time, their feed intake, water intake, and live bo ... | 2000 | 10857928 |
| probiotics in the management of atopic eczema. | over the last two decades the incidence of allergic diseases has increased in industrialized countries, and consequently new approaches have to be explored. | 2000 | 11069570 |
| enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (bifidobacterium lactis hn019): optimization and definition of cellular immune responses. | to define the cellular basis for immune enhancement by a probiotic lactic acid bacteria strain (bifidobacterium lactis hn019); and to determine whether immune enhancement can be optimized by delivery in oligosaccharide-enriched low-fat milk. | 2000 | 11114680 |
| bifidobacterium lactis meile et al. 1997 is a subjective synonym of bifidobacterium animalis (mitsuoka 1969) scardovi and trovatelli 1974. | bifidobacterium lactis jcm 10602t (t = type strain) and bifidobacterium animalis jcm 1190t were found to be phenotypically similar. these strains were subjected to investigation of their genetic relationships. the 16s rrna sequence of b. animalis jcm 1190t was aligned with that of other bifidobacterium species. b. animalis and b. lactis were the most closely related species in the phylogenetic tree and showed a high similarity in sequences (98.8%). the levels of dna-dna hybridization between the ... | 2000 | 11128064 |
| selection of a bifidobacterium strain to complement resistant starch in a synbiotic yoghurt. | to employ an in vitro screening regime to select a probiotic bifidobacterium strain to complement resistant starch (hi-maizetrade mark) in a synbiotic yoghurt. | 2001 | 11168730 |
| potential probiotic lactic acid bacteria lactobacillus rhamnosus (hn001), lactobacillus acidophilus (hn017) and bifidobacterium lactis (hn019) do not degrade gastric mucin in vitro. | the mucus layer (mucin) coating the surface of the gastrointestinal tract (git) plays an important role in the mucosal barrier system. any damage or disturbance of this mucin layer will compromise the host's mucosal defence function. in the present study, the ability of three potential probiotic lactic acid bacteria (lab) strains (lactobacillus rhamnosus hn001, lactobacillus acidophilus hn017, bifidobacterium lactis hn019) to degrade mucin in vitro was evaluated, in order to assess their potenti ... | 2001 | 11205957 |
| adherence of probiotic bacteria to human intestinal mucus in healthy infants and during rotavirus infection. | the concentration of fecal mucin and the adhesion of specific probiotics and their combinations in the intestinal mucus of infants during and after rotavirus diarrhea and in healthy children were determined. mucus was prepared from fecal samples from 20 infants during and after rotavirus diarrhea and from 10 healthy age-matched children. mucin concentration was determined, and the adhesion of five probiotics-lactobacillus rhamnosus gg, lactobacillus casei shirota, lactobacillus paracasei f19, la ... | 2001 | 11238211 |
| characterization of the d-xylulose 5-phosphate/d-fructose 6-phosphate phosphoketolase gene (xfp) from bifidobacterium lactis. | a d-xylulose 5-phosphate/d-fructose 6-phosphate phosphoketolase (xfp) from the probiotic bifidobacterium lactis was purified to homogeneity. the specific activity of the purified enzyme with d-fructose 6-phosphate as a substrate is 4.28 units per mg of enzyme. k(m) values for d-xylulose 5-phosphate and d-fructose 6-phosphate are 45 and 10 mm, respectively. the native enzyme has a molecular mass of 550,000 da. the subunit size upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis (90,000 ... | 2001 | 11292814 |
| characterization of the properties of human- and dairy-derived probiotics for prevention of infectious diseases in fish. | the present study aimed to investigate the potential probiotic properties of six lactic acid bacteria (lab) intended for human use, lactobacillus rhamnosus atcc 53103, lactobacillus casei shirota, lactobacillus bulgaricus, l. rhamnosus lc 705, bifidobacterium lactis bb12, and lactobacillus johnsonii la1, and one for animal use, enterococcus faecium tehobak, for use as a fish probiotic. the strains for human use were specifically chosen since they are known to be safe for human use, which is of m ... | 2001 | 11375147 |
| specific identification and targeted characterization of bifidobacterium lactis from different environmental isolates by a combined multiplex-pcr approach. | the species bifidobacterium lactis, with its main representative strain bb12 (dsm 10140), is a yoghurt isolate used as a probiotic strain and is commercially applied in different types of yoghurts and infant formulas. in order to ensure the genetic identity and safety of this bacterial isolate, species- and strain-specific molecular tools for genetic fingerprinting must be available to identify isolated bifidobacteria or lactic acid bacteria from, e.g., various clinical environments of relevance ... | 2001 | 11375192 |
| a dietary probiotic (bifidobacterium lactis hn019) reduces the severity of escherichia coli o157:h7 infection in mice. | the protective effects of the probiotic bifidobacterium lactis hn019 against escherichia coli o157:h7 were investigated in murine challenge infection models. balb/c or c57bl/6 mice were fed milk-based diets supplemented with b. lactis hn019 (3 x 10(8) cfu/g) for 7 days prior to and following oral challenge with e. coli o157:h7. behavioral parameters (morbidity, feed intake) were measured for 7 days following challenge; immunological responses (phagocytosis, antibody) and pathogen translocation w ... | 2001 | 11388612 |
| isolation and characterization of human colonic bacteria able to hydrolyse chlorogenic acid. | conjugated hydroxycinnamates, such as chlorogenic acid (caffeoyl-quinic acid), are widely consumed in a western diet, coffee being one of the richest sources. ingested hydroxycinnamate esters can reach the large intestine essentially unaltered, and may then be hydrolysed by esterases produced by the indigenous microflora. this study is aimed at identifying bacterial species responsible for the release of natural antioxidants, such as hydroxycinnamic acids, in the human large intestine. | 2001 | 11412317 |
| molecular microbial analysis of bifidobacterium isolates from different environments by the species-specific amplified ribosomal dna restriction analysis (ardra). | one hundred and six isolates of the genus bifidobacterium, isolated from different environments (mainly gastrointestinal), were identified and classified taxonomically to species level by amplified ribosomal dna restriction analysis. two restriction endonucleases (sau3ai and bamhi) were chosen for aligning the 16s rrna sequences of 16 bifidobacterial species retrieved from various databases, to obtain species-specific restriction patterns. a rapid and accurate identification scheme was obtained ... | 2001 | 11451515 |
| dietary probiotic supplementation enhances natural killer cell activity in the elderly: an investigation of age-related immunological changes. | many elderly subjects are at increased risk of infectious and noninfectious diseases due to an age-related decline in lymphoid cell activity (immunosenescence). noninvasive means of enhancing cellular immunity are therefore desirable in the elderly. previous reports have suggested that dietary supplementation could represent an effective means of enhancing the activity of circulating natural killer (nk) cells in the elderly. in the present study, we have conducted a pre-post intervention trial t ... | 2001 | 11506196 |
| polymerase chain reaction and denaturing gradient gel electrophoresis monitoring of fecal bifidobacterium populations in a prebiotic and probiotic feeding trial. | a culture-independent approach based on genus-specific pcr and denaturing gradient gel electrophoresis (dgge) was used to monitor qualitative changes in fecal bifidobacterial communities in a human feeding trial. dna was extracted directly from feces and bifidobacterial 16s rdna sequences were amplified using genus-specific pcr. the pcr fragments were subsequently separated in a sequence-specific manner by dgge in order to obtain a profile of bifidobacterial fragments. the dgge profiles revealed ... | 2001 | 11518325 |
| in vitro adherence properties of lactobacillus rhamnosus dr20 and bifidobacterium lactis dr10 strains and their antagonistic activity against an enterotoxigenic escherichia coli. | adhesion and colonisation properties of three probiotic strains namely, lactobacillus rhamnosus dr20, l. acidophilus hn017, and bifidobacterium lactis dr10, were determined in vitro using the differentiated human intestinal cell-lines including ht-29, caco-2, and ht29-mtx, and compared with properties of l. acidophilus la-1 and l. rhamnosus gg (two commercial probiotic strains). two independent methods were employed to quantitate the "adhesiveness" of each strain. in the first method, the bacter ... | 2001 | 11518430 |
| probiotic treatment using bifidobacterium lactis hn019 reduces weanling diarrhea associated with rotavirus and escherichia coli infection in a piglet model. | diarrhea associated with rotavirus and escherichia coli is one of the major gastrointestinal problems faced by human infants. using a piglet model, the authors investigated the protective effectiveness of probiotic feeding against naturally acquired diarrhea in weanlings. | 2001 | 11568519 |
| new approach to phylogenetic analysis of the genus bifidobacterium based on partial hsp60 gene sequences. | the partial 60 kda heat-shock protein (hsp60) genes of 36 bifidobacterium strains representing 30 different bifidobacterium species and subspecies and of the type strain of gardnerella vaginalis were cloned and sequenced using a pair of universal degenerate hsp60 pcr primers. the hsp60 dna sequence similarities were determined for the taxa at various ranks as follows: 99.4-100% within the same species, 96% at the subspecies level, and 73-96% (mean 85%) at the interspecies level (and 98% in the c ... | 2001 | 11594590 |
| enhancement of immunity in the elderly by dietary supplementation with the probiotic bifidobacterium lactis hn019. | the aging process can lead to a decline in cellular immunity. therefore, the elderly could benefit from safe and effective interventions that restore cellular immune functions. | 2001 | 11722966 |
| adhesive property of bifidobacterium lactis lkm512 and predominant bacteria of intestinal microflora to human intestinal mucin. | the adhesive property to the intestinal mucin of bifidobacterium lactis lkm512, b. longum, b. breve, b. bifidum, b. adolescentis, b. infantis, bacteroides vulgatus, bacteroides distasonis, eubacterium aerofaciens, clostridium perfringens, escherichia coli, and lactobacillus acidophilus were examined. adhesive rate of lkm512 to the mucin was significantly (p < 0.05, 0.01, or 0.001) stronger than the other strains from 2 to 100 time. though the adhesive property of many strains was almost same to ... | 2002 | 11821930 |
| expression of the xylulose 5-phosphate phosphoketolase gene, xpka, from lactobacillus pentosus md363 is induced by sugars that are fermented via the phosphoketolase pathway and is repressed by glucose mediated by ccpa and the mannose phosphoenolpyruvate phosphotransferase system. | purification of xylulose 5-phosphate phosphoketolase (xpka), the central enzyme of the phosphoketolase pathway (pkp) in lactic acid bacteria, and cloning and sequence analysis of the encoding gene, xpka, from lactobacillus pentosus md363 are described. xpka encodes a 788-amino-acid protein with a calculated mass of 88,705 da. expression of xpka in escherichia coli led to an increase in xpka activity, while an xpka knockout mutant of l. pentosus lost xpka activity and was not able to grow on ener ... | 2002 | 11823225 |
| probiotic supplementation reduces the risk of bacterial translocation in experimental short bowel syndrome. | probiotics are live organisms that survive passage through the gastrointestinal tract and have beneficial effects on the host. lactobacillus and bifidobacterium have been recommended for cholesterol lowering, acute diarrhea, prevention of cancer, or inflammatory bowel disease. on the other hand, after massive bowel resection, bacterial overgrowth is frequent and favors bacterial translocation (bt). the possible beneficial effects of bifidobacterium lactis (bl) administration on bt in experimenta ... | 2002 | 11987081 |
| application of nontraditional meat starter cultures in production of hungarian salami. | listeria monocytogenes and escherichia coli o111 have been implicated in several outbreaks of food-borne disease linked to smallgoods products. traditional meat starter cultures, containing a mixture of lactic acid bacteria (lab) and staphylococci, are used to maintain safety and sensory properties of hungarian salami. the present study investigated if nontraditional meat starter (ntms) cultures can be used for improving the safety of hungarian salami. salami batter was inoculated with list. mon ... | 2002 | 12038580 |
| aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning? | recent data have outlined a relationship between the composition of the intestinal microflora and allergic inflammation, and demonstrated the competence of probiotics in downregulation of such inflammation. | 2002 | 12077091 |
| pcr-elisa ii: analysis of bifidobacterium populations in human faecal samples from a consumption trial with bifidobacterium lactis bb-12 and a galacto-oligosaccharide preparation. | a pcr-elisa method was extended for detection of most common bifidobacterium species in humans and applied to a feeding trial including administration of bifidobacterium lactis bb-12 and galacto-oligosaccharide (gos)-containing syrup as probiotic and prebiotic preparations, respectively. for pcr-elisa, oligonucleotide probes based on 16s rdna sequences were designed and tested for specificity and sensitivity with nine different bifidobacterial species followed by analysis of faecal samples. bifi ... | 2002 | 12353880 |
| microencapsulation of l. acidophilus (la-05) and b. lactis (bb-12) and evaluation of their survival at the ph values of the stomach and in bile. | microcapsules were prepared using the probiotic microorganisms lactobacillus acidophilus (la-05) and bifidobacterium lactis (bb-12) and the spray drying technique and cellulose acetate phthalate as the wall material. this study evaluated the resistance of these microorganisms to drying at three temperatures and also the in vitro tolerance of the free and microencapsulated form to ph values and bile concentrations similar to those found in the human stomach and intestine. with an air entry temper ... | 2002 | 12396385 |
| multiparametric flow cytometry and cell sorting for the assessment of viable, injured, and dead bifidobacterium cells during bile salt stress. | using a flow cytometry-based approach, we assessed the viability of bifidobacterium lactis dsm 10140 and bifidobacterium adolescentis dsm 20083 during exposure to bile salt stress. carboxyfluorescein diacetate (cfda), propidium iodide (pi), and oxonol [dibac4(3)] were used to monitor esterase activity, membrane integrity, and membrane potential, respectively, as indicators of bacterial viability. single staining with these probes rapidly and noticeably reflected the behavior of the two strains d ... | 2002 | 12406706 |
| antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics lactobacillus rhamnosus and bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats. | prebiotics such as fructans, and probiotics such as lactobacilli or bifidobacteria, or a combination of prebiotics and probiotics (synbiotics) are thought to be protective against colon cancer. therefore, we studied whether the prebiotic inulin enriched with oligofructose (raftilose-synergy1, briefly, synergy1, 10% of the diet), probiotics [bifidobacterium lactis (bb12) and lactobacillus rhamnosus (lgg), each at 5x10(8) c.f.u./g diet] or synbiotics (a combination of the two) protect rats against ... | 2002 | 12419846 |
| rapid identification, differentiation, and proposed new taxonomic classification of bifidobacterium lactis. | identification of bifidobacterium lactis and bifidobacterium animalis is problematic because of phenotypic and genetic homogeneities and has raised the question of whether they belong to one unique taxon. analysis of the 16s-23s internally transcribed spacer region of b. lactis dsm10140(t), b. animalis atcc 25527(t), and six potential b. lactis strains suggested two distinct clusters. two specific 16s-23s spacer rrna gene-targeted primers have been developed for specific detection of b. animalis ... | 2002 | 12450873 |
| interaction between probiotic lactic acid bacteria and canine enteric pathogens: a risk factor for intestinal enterococcus faecium colonization? | selected probiotic lactic acid bacteria (lab) have been shown to elicit positive health effects particularly in humans. competitive exclusion of pathogens is one of the most important beneficial health claims of probiotic bacteria. the effect of probiotic lab on competitive exclusion of pathogens has been demonstrated in humans, chicken and pigs. in this study we evaluated the ability of certain lab strains (lactobacillus rhamnosus gg, bifidobacterium lactis bb12, lactobacillus pentosus uk1a, l. ... | 2003 | 12488075 |
| induction of sucrose utilization genes from bifidobacterium lactis by sucrose and raffinose. | the probiotic organism bifidobacterium lactis was isolated from a yoghurt starter culture with the aim of analyzing its use of carbohydrates for the development of prebiotics. a sucrose utilization gene cluster of b. lactis was identified by complementation of a gene library in escherichia coli. three genes, encoding a sucrose phosphorylase (scrp), a galr-laci-type transcriptional regulator (scrr), and a sucrose transporter (scrt), were identified by sequence analysis. the scrp gene was expresse ... | 2003 | 12513973 |
| [beneficial effects of bifidobacterium lactis in the prevention of bacterial translocation in experimental short bowel syndrome]. | probiotics are live organisms that survive passage through the gastrointestinal tract and have beneficial effects on the host. lactobacillus and bifidobacterium have been recommended in cholesterol lowering, acute diarrhea, prevention of cancer or inflammatory bowel disease. on the other hand, after massive bowel resection bacterial overgrowth is frequent and favours the occurrence of bacterial translocation (bt). the possible beneficial effects of bifidobacterium lactis (bl) administration on b ... | 2002 | 12601975 |
| an in vitro model for investigating intestinal adhesion of potential dairy propionibacteria probiotic strains using cell line c2bbe1. | the purposes of this study were to screen the adhesion properties of dairy propionibacteria strains and evaluate whether c2bbe1 could be used in the screening of potential probiotic strains. | 2003 | 12641713 |
| identification of the gene for beta-fructofuranosidase of bifidobacterium lactis dsm10140(t) and characterization of the enzyme expressed in escherichia coli. | bifidobacterium lactis is a moderately oxygen-tolerant, saccharolytic bacterium often used in combination with fructooligosaccharides (fos) as a probiotic supplement in diverse dairy products. this is the first report describing the gene structure and enzymatic properties of a beta-fructofuranosidase [ec 3.2.1.26] from bifidobacteria. bfra was identified in bifidobacterium lactis dsm 10140(t) and heterologously expressed in escherichia coli. the g+c content was identical with the g+c content as ... | 2003 | 12732943 |
| lactobacillus acidophilus, bifidobacterium lactis and lactobacillus f19 prevent antibiotic-associated ecological disturbances of bacteroides fragilis in the intestine. | the objective of this study was to compare the effect of clindamycin on the intestinal microflora in subjects ingesting yogurt with added probiotic microorganisms with the microflora in subjects ingesting placebo yogurt. | 2003 | 12865387 |
| effect of probiotic bacteria on induction and maintenance of oral tolerance to beta-lactoglobulin in gnotobiotic mice. | in this study, the effect of lactobacillus paracasei (ncc 2461), lactobacillus johnsonii (ncc 533) and bifidobacterium lactis bb12 (ncc 362) on the induction and maintenance of oral tolerance to bovine beta-lactoglobulin (blg) was investigated in mice. germfree mice were monocolonized with one of the three strains before oral administration of whey protein to induce tolerance. mice were then injected with blg and sacrificed 28 or 50 days after whey protein feeding for humoral and cellular respon ... | 2003 | 12965905 |
| comparative sequence analysis of the tuf and reca genes and restriction fragment length polymorphism of the internal transcribed spacer region sequences supply additional tools for discriminating bifidobacterium lactis from bifidobacterium animalis. | the relationship between bifidobacterium lactis and bifidobacterium animalis was examined by comparative analysis of tuf and reca gene sequences and by restriction fragment length polymorphism analysis of their internal 16s-23s transcribed spacer region sequences. the bifidobacterial strains investigated could be divided into two distinct groups within a single species based on the tuf, reca, and 16s-23s spacer region sequence analysis. therefore, all strains of b. lactis and b. animalis could b ... | 2003 | 14660406 |
| prebiotic inulin enriched with oligofructose in combination with the probiotics lactobacillus rhamnosus and bifidobacterium lactis modulates intestinal immune functions in rats. | probiotics (pro) modulate systemic immunity in animals and humans. in contrast, the effects of prebiotics (pre) on systemic and intestinal immunity have not been investigated. whether the combined application of pro and pre [synbiotics (syn)] has synergistic or additive effects is presently unknown. therefore, pro (lactobacillus rhamnosus gg and bifidobacterium lactis bb12), pre (inulin enriched with oligofructose), and syn (combination of pro and pre) were fed to f344 rats for 4 wk as supplemen ... | 2004 | 14704309 |
| randomised clinical trial of synbiotic therapy in elective surgical patients. | it is possible to manipulate the composition of the gastrointestinal microflora by administration of pre- and probiotics. this may help to preserve gut barrier function and reduce the incidence of septic morbidity. | 2004 | 14724157 |
| long-term consumption of infant formulas containing live probiotic bacteria: tolerance and safety. | nonpathogenic live bacteria are consumed as food by many children, particularly in the form of yogurt. the tolerance and safety of long-term consumption of specific types and strains of probiotic bacteria are not well documented. | 2004 | 14749232 |
| acidified milk formula supplemented with bifidobacterium lactis: impact on infant diarrhea in residential care settings. | probiotics may be useful in preventing acute infectious diarrhea. bifidobacteria are particularly attractive as probiotics agent because they constitute the predominant colonic flora of breastfed infants and are thought to play a role in the decreased incidence of diarrhea in breastfed infants. | 2004 | 15076628 |
| probiotics enhance recovery from malnutrition and lessen colonic mucosal atrophy after short-term fasting in rats. | we investigated the effects of probiotics on nutritional status and gut mucosal atrophy after fasting. | 2004 | 15105036 |
| bifidobacterium lactis dsm 10140: identification of the atp (atpbefhagdc) operon and analysis of its genetic structure, characteristics, and phylogeny. | the atp operon is highly conserved among eubacteria, and it has been considered a molecular marker as an alternative to the 16s rrna gene. pcr primers were designed from the consensus sequences of the atpd gene to amplify partial atpd sequences from 12 bifidobacterium species and nine lactobacillus species. all pcr products were sequenced and aligned with other atpd sequences retrieved from public databases. genes encoding the subunits of the f(1)f(0)-atpase of bifidobacterium lactis dsm 10140 ( ... | 2004 | 15128574 |
| h+-atpase activity in bifidobacterium with special reference to acid tolerance. | the acid tolerance of 17 strains of nine species of bifidobacteria was compared using brief exposures to acidic conditions (ph 2-5). in addition, because it has been hypothesized that the acid tolerance of bifidobacteria depends on h+-atpase activity, the activity of this enzyme in various strains and species was compared. in general, the acid tolerance of bifidobacteria was found to be weak, with the exception of bifidobacterium lactis and bifidobacterium animalis. high numbers of all strains o ... | 2004 | 15135587 |
| determinations of the antimutagenic activities of several probiotic bifidobacteria under acidic and bile conditions against benzo[a]pyrene by a modified ames test. | antimutagenic activities of six bifidobacteria, after acidic and bile treatment mimicking gastrointestinal conditions, against benzo[a]pyrene (b[a]p) were determined by a modified ames test using salmonella typhimurium ta 100. results showed that when bifidobacteria were treated at ph 2.0 for 3 h or 1% bile for 6 h, their antimutagenic activities against b[a]p were increased as compared to controls at ph 7.0 for 0 h. after sequential acidic ph and bile treatments, bifidobacterium lactis bb-12 di ... | 2004 | 15135962 |
| hydrolysis of oligofructoses by the recombinant beta-fructofuranosidase from bifidobacterium lactis. | the ability of the beta-fructofuranosidase (ec 3.2.1.26) from bifidobacterium lactis dsm 10140t to cleave a variety of fructooligosaccharides was characterised. we identified its gene on a cloned chromosomal dna fragment by sequence similarity (69% identity) to the putative csca protein encoded in the bifidobacterium longum genome. the deduced amino acid sequence of 532 residues (59.4 kda) appeared to be identical to the beta-fructofuranosidase from the same strain recently described by ehrmann ... | 2004 | 15214632 |
| inhibitory effect of yoghurt and soya yoghurt containing bifidobacteria on the proliferation of ehrlich ascites tumour cells in vitro and in vivo in a mouse tumour model. | the effect of yoghurt and soya yoghurt containing bifidobacterium lactis bb-12 or b. longum bb-46 on ehrlich ascites tumour cell proliferation was investigated in vitro and in vivo. tumour cells were incubated with b. lactis bb-12 or b. longum bb-46 cultivated in de mann rogosa sharpe (mrs) broth medium, or with their centrifuged supernatant fractions or sediments, for 2 h at 37 degrees c. treatment resulted in the inhibition of tumour cell proliferation by 85.42 (sd 0.78) and 85.10 (sd 1.28) % ... | 2004 | 15230990 |
| use of a probiotic bifidobacterium in a dry food matrix, an in vivo study. | probiotics are commonly included in dairy products. these products require cold storage and transportation, which limits their use. here, we describe the inclusion of the probiotic strain bifidobacterium lactis bb-12 in a dry food matrix, an oat-based cereal bar, and its detection in faeces after consumption of this product. one week after cessation of b. lactis bb-12 feeding, it could be identified in the faeces of five of the nine subjects. | 2004 | 15240080 |
| rapid identification of stress-related fingerprint from whole bacterial cells of bifidobacterium lactis using matrix assisted laser desorption/ionization mass spectrometry. | whole cells of bifidobacterium lactis were analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tofms). characteristic and reproducible mass spectra were obtained in the mass range from 6 to 19 kda. after several days of bacterial cell storage at 4 degrees c (d0, d2, and d6), only minor signal differences were observed. under identical and reproducible conditions, fourteen relevant diagnostic ions were identified. moreover, control- and stress-related f ... | 2004 | 15276169 |
| polyphasic taxonomic analysis of bifidobacterium animalis and bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of bifidobacterium animalis as bifidobacterium animalis subsp. animalis subsp. nov. and bifidobacterium lactis as bifidobacterium animalis subsp. lactis subsp. nov. | the taxonomic standing of bifidobacterium lactis and bifidobacterium animalis was investigated using a polyphasic approach. sixteen representatives of both taxa were found to be phenotypically similar and shared more than 70% dna-dna relatedness (76-100%), which reinforces the conclusions of previous studies in which b. lactis and b. animalis were considered to be one single species. however, the results of protein profiling, box-pcr fingerprinting, fluorescent amplified fragment length polymorp ... | 2004 | 15280282 |
| influence of synbiotic containing lactobacillus acidophilus la5, bifidobacterium lactis bb 12, streptococcus thermophilus, lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial. | infective complications are a common cause of mortality and morbidity in critically ill patients. many factors affect sepsis, one of which is gut barrier function. the aim of this study was to determine whether the oral administration of a synbiotic preparation could alter gut barrier function in critically ill patients and thus reduce sepsis. | 2004 | 15297081 |
| effects of ingesting lactobacillus- and bifidobacterium-containing yogurt in subjects with colonized helicobacter pylori. | evidence suggests that ingesting lactic acid bacteria exerts a suppressive effect on helicobacter pylori infection in both animals and humans. supplementing with lactobacillus- and bifidobacterium-containing yogurt (ab-yogurt) was shown to improve the rates of eradication of h. pylori in humans. | 2004 | 15321816 |
| characterization and heterologous expression of the oxalyl coenzyme a decarboxylase gene from bifidobacterium lactis. | oxalyl coenzyme a (coa) decarboxylase (oxc) is a key enzyme in the catabolism of the highly toxic compound oxalate, catalyzing the decarboxylation of oxalyl-coa to formyl-coa. the gene encoding a novel oxalyl-coa decarboxylase from bifidobacterium lactis dsm 10140 (oxc) was identified and characterized. this strain, isolated from yogurt, showed the highest oxalate-degrading activity in a preliminary screening with 12 strains belonging to bifidobacterium, an anaerobic intestinal bacterial group l ... | 2004 | 15345383 |
| lactobacillus paracasei normalizes muscle hypercontractility in a murine model of postinfective gut dysfunction. | the effects of probiotics on gut dysfunction in postinfective irritable bowel syndrome are unknown. we tested whether probiotics influence persistent muscle hypercontractility in mice after recovery from infection with trichinella spiralis and analyzed the underlying mechanisms. | 2004 | 15362038 |
| fecal water genotoxicity is predictive of tumor-preventive activities by inulin-like oligofructoses, probiotics (lactobacillus rhamnosus and bifidobacterium lactis), and their synbiotic combination. | the measurement of fecal water genotoxicity in human colon cells could be a useful biomarker to study effects of diet in the colon. here we assessed aqueous fecal extracts of samples from a chronic study with rats fed prebiotics, probiotics, and their combination. treatments were maltodextrins (controls), inulin/oligofructoses (prebiotic), lactobacillus rhamnosus, and bifidobacterium lactis (probiotics) or both (synbiotic). azoxymethane (aom) was administered to initiate tumors. rat feces were c ... | 2004 | 15489207 |
| consumption of bifidobacterium lactis lkm512 yogurt reduces gut mutagenicity by increasing gut polyamine contents in healthy adult subjects. | the possible role of probiotic metabolites on human health effects of probiotics has received little research attention. in this study, we investigated the effects of consumption of bifidobacterium lactis lkm512-containing yogurt (lkm512 yogurt) on fecal probiotic metabolites (polyamines, lactate, and acetate) and mutagenicity in seven healthy adults (one male and six females; average age: 30.5 years). each volunteer was provided with 100g/day of lkm512 yogurt or placebo for 2 weeks. fecal polya ... | 2004 | 15542102 |
| intestinal immunity of rats with colon cancer is modulated by oligofructose-enriched inulin combined with lactobacillus rhamnosus and bifidobacterium lactis. | probiotics (pro) are known to modulate immunity in animals and human subjects and to inhibit colon carcinogenesis in experimental models, but the effects of synbiotics (syn) are not well understood. therefore, the effects of pro (lactobacillus rhamnosus gg and bifidobacterium lactis bb12), pre (inulin-based enriched with oligofructose, 100 g/kg) and syn (combination of pro and pre) on the immune system of rats were investigated in the azoxymethane (aom)-induced colon cancer model. after 33 weeks ... | 2004 | 15613255 |
| microbiological effects of consuming a synbiotic containing bifidobacterium bifidum, bifidobacterium lactis, and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria. | because of changes in gut physiology, immune system reactivity, and diet, elderly people are more susceptible to gastrointestinal infections than are younger adults. the gut microflora, which provides a natural defense against invading microorganisms, changes in elderly people with the development of potentially damaging bacterial populations, which may lead to alterations in bacterial metabolism and higher levels of infection. | 2004 | 15614689 |
| effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents. | to investigate the effect of 2 different species of probiotics in preventing infections in infants attending child care centers. | 2005 | 15629974 |
| antibiotic susceptibility profiles of new probiotic lactobacillus and bifidobacterium strains. | the antimicrobial susceptibilities and presence of plasmids in four new probiotic lactic acid bacteria (lab) strains, lactobacillus rhamnosus hn001 (dr20) hn067, lactobacillus acidophilus hn017 and bifidobacterium lactis hn019 (dr10), were determined. resistance to 18 commonly used antibiotics was assessed by disk diffusion. the three lactobacillus strains had similar antibiotic susceptibility profiles to those of lactobacillus plantarum strain hn045 and two commercial probiotic lactobacillus st ... | 2005 | 15681048 |
| molecular and microbiological analysis of caecal microbiota in rats fed with diets supplemented either with prebiotics or probiotics. | the potential health-improving effects of both a prebiotic and a probiotic infant formula have been evaluated in a rat model. two groups of 10 rats were fed with either prebiotics containing fructo-oligosaccharides or probiotics containing viable bifidobacterium lactis and streptococcus thermophilus. the composition of their caecal microbiota was analyzed both by classical plate count of the main bacterial groups and by pcr amplification of a v3 fragment of 16s rrna genes and denaturing gradient ... | 2005 | 15698689 |
| detection and quantification of bifidobacterium lactis lafti b94 in human faecal samples from a consumption trial. | a method was developed to allow detection of the probiotic bifidobacterium lactis lafti b94 in human clinical samples. a new probe, laf94p, was developed to accomplish colony hybridization of b. lactis b94. pcr detection of b94 was also achieved using the species-specific (b. lactis) primer pair. these tests and probes allowed detection and quantification of b94 in the human intestinal flora. the sensitivity of the probe was assessed by monitoring faecal levels of b94 in humans who were fed the ... | 2005 | 15727827 |
| bifidobacterium lactis sp. 420 up-regulates cyclooxygenase (cox)-1 and down-regulates cox-2 gene expression in a caco-2 cell culture model. | cyclooxygenases (cox) -1 and -2 play important roles in gastrointestinal health; chronic overexpression of cox-2 is associated with inflammatory and cancerous disease, whereas cox-1 is expressed constitutively. we studied the effects of two probiotic (bifidobacterium lactis sp. 420 and lactobacillus acidophilus) and two control microorganisms (escherichia coli and salmonella enteritidis) and four microbial metabolites (acetate, butyrate, lactate and propionate) on the expression levels of the co ... | 2005 | 15749634 |
| a randomized formula controlled trial of bifidobacterium lactis and streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants. | this clinical trial was carried out to determine whether oral treatment with a commercial probiotic formula containing bifidobacterium lactis and streptococcus thermophilus would reduce the frequency of antibiotic-associated diarrhea (aad) in infants. | 2005 | 15815206 |
| application of a microplate scale fluorochrome staining assay for the assessment of viability of probiotic preparations. | cell viability in probiotic preparations is traditionally assessed by the plate count technique. additionally, fluorescent staining combined with epifluorescence microscopy or flow cytometry has been developed for the viability assessment, but the currently available assays are either laborious or require highly sophisticated equipment. the aim of this study was to investigate the applicability of a microplate scale fluorochrome assay for predicting the cell state of freeze-dried lactobacillus r ... | 2005 | 15823392 |
| a synbiotic combination of resistant starch and bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged cells in rat colon. | recent reports suggest that combinations of prebiotics and probiotics may be protective against colorectal cancer. we examined in rats the effects of probiotic bacteria, resistant starch (rs), and their interaction on luminal and epithelial events of relevance to the development of colorectal cancer. lyophilized cultures (1 x 10(10) cfu/g) of lactobacillus acidophilus and/or bifidobacterium lactis were added at a concentration of 1% by weight to a semipurified diet containing either low-rs (no s ... | 2005 | 15867271 |
| removal of the cyanobacterial toxin microcystin-lr by human probiotics. | three human probiotics, lactobacillus rhamnosus strains gg and lc-705, and bifidobacterium lactis strain bb12, were found to bind the cyanobacterial peptide toxin microcystin-lr from water solutions. the highest removal percentage was 46%, observed with heat-treated l. rhamnosus strain gg (10(10) cells/ml) and a microcystin-lr concentration of 0.5 microg/ml during an incubation of 7 h at 35 degrees c. | 2005 | 15922388 |
| raffinose family of oligosaccharides from lupin seeds as prebiotics: application in dairy products. | the raffinose family of oligosaccharides (rfos) isolated from lupin seeds (lupinus albus var. multolupa) was evaluated for bifidogenic effects during the manufacture of probiotic fermented milk. a mixed starter inoculum was composed of bifidobacterium lactis bb-12 and lactobacillus acidophilus (1:1). lupins are a rich source of rfos that can be used as functional food ingredients. the addition of rfos to milk increased b. lactis bb-12 and l. acidophilus populations at the final fermentation time ... | 2005 | 15954717 |
| culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria. | a total of 58 probiotic products obtained worldwide, which were claimed to contain bifidobacterium strains (including 22 yoghurts, 5 dairy fruit drinks, 28 food supplements and 3 pharmaceutical preparations) were investigated in parallel using a culture-dependent and a culture-independent approach. three isolation media previously reported as selective for bifidobacterium were evaluated for their suitability in the quality analysis of these products. subsequently, possible bifidobacterial coloni ... | 2005 | 15992621 |
| use of traditional african fermented beverages as delivery vehicles for bifidobacterium lactis dsm 10140. | a microencapsulation delivery system for bifidobacterium lactis, a possible probiotic suited for use by the rural population of south africa, was evaluated using two existing traditional fermented foods, amasi and mahewu. gellan/xanthan microcapsules containing viable b. lactis, were tested under simulated physiological conditions, and added to pasteurized beverages. the capsules protected the organism under simulated low ph conditions associated with the stomach and from the biocidal activity o ... | 2005 | 15992622 |
| innate mechanisms for bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats. | bifidobacteria comprise a dominant microbial population group in the human intestinal tract with purported beneficial health effects on the host. in this study, we characterized the molecular mechanisms for the initial interaction of probiotic bifidobacterium lactis strain bb12 with native and intestinal epithelial cell (iec) lines. we showed that b. lactis-monoassociated fisher f344 rats transiently induce phosphorylation/activation of the nf-kappab transcriptionally active subunit rela and the ... | 2005 | 16011513 |
| the effect of probiotics on the genotoxicity of furazolidone. | antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay sos chromotest, with escherichia coli pq37 as the test organism. the supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on sos induction produced by furazolidone on e. coli pq 37 (sfia: lacz). genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. the highest genotoxicity inhibition was detect ... | 2005 | 16014301 |
| immunostimulatory probiotic lactobacillus rhamnosus hn001 and bifidobacterium lactis hn019 do not induce pathological inflammation in mouse model of experimental autoimmune thyroiditis. | the possibility that intestinal microflora contribute to the pathogenesis of autoimmune diseases has raised issues regarding the safety of probiotic organisms, especially those with immunostimulating properties, in individuals with such immune dysfunctions. in this study, the effect of consumption of probiotic lactic acid bacteria (lab) strains lactobacillus rhamnosus hn001(hn001) and bifidobacterium lactis hn019 (hn019) on the induction and progression of experimental autoimmune thyroiditis (ea ... | 2005 | 16084270 |
| evaluation of a diet containing probiotics and zinc for the treatment of mild diarrheal illness in children younger than one year of age. | supplementation of probiotics and supplementation of zinc during acute gastroenteritis in children have been shown to exert positive effects on diarrhea duration and severity. our aim was to evaluate a new diet enriched with zinc and probiotic bacteria in the treatment of acute gastroenteritis in young children. | 2005 | 16192262 |
| relationship between dietary-induced changes in intestinal commensal microflora and duodenojejunal myoelectric activity monitored by radiotelemetry in the rat in vivo. | interdigestive intestinal motility, and especially phase iii of the migrating myoelectric/motor complex (mmc), is responsible for intestinal clearance and plays an important role in prevention of bacterial overgrowth and translocation in the gut. yet previous results from gnotobiotic rats have shown that intestinal microflora can themselves affect the characteristics of the myoelectric activity of the gut during the interdigestive state. given that the composition of the intestinal microflora ca ... | 2006 | 16263800 |
| a bile salt-resistant derivative of bifidobacterium animalis has an altered fermentation pattern when grown on glucose and maltose. | the growth of bifidobacterium animalis subsp. lactis ipla 4549 and its derivative with acquired resistance to bile, b. animalis subsp. lactis 4549dox, was evaluated in batch cultures with glucose or the glucose disaccharide maltose as the main carbon source. the acquisition of bile salt resistance caused a change in growth pattern for both sugars, which mainly resulted in a preferential use of maltose compared to glucose, whereas the mother strain used both carbohydrates in a similar way. high-p ... | 2005 | 16269682 |
| oxalate degrading bacteria: new treatment option for patients with primary and secondary hyperoxaluria? | current treatment options in patients with primary and secondary hyperoxaluria are limited and do not always lead to sufficient reduction in urinary oxalate excretion. intestinal oxalate degrading bacteria are capable of degrading oxalate to co(2) and formate, the latter being further metabolized and excreted via the feces. it is speculated, that both endogenously produced, as well as dietary oxalate can be significantly removed via the intestinal tract. oxalobacter formigenes, an obligate anaer ... | 2005 | 16284877 |
| inability of probiotic bacterial strains lactobacillus rhamnosus hn001 and bifidobacterium lactis hn019 to induce human platelet aggregation in vitro. | platelet aggregation contributes to the pathogenesis of infective endocarditis, and aggregation of platelets induced by lactobacilli is thought to be an important contributory factor in the development and progression of lactobacillus endocarditis. the main purpose of this study was to examine the effect of immunity-enhancing probiotic strains lactobacillus rhamnosus hn001 and bifidobacterium lactis hn019 on the activation and aggregation of human blood platelets. whole blood samples from health ... | 2005 | 16300090 |
| enzymatic ability of bifidobacterium animalis subsp. lactis to hydrolyze milk proteins: identification and characterization of endopeptidase o. | the proteolytic system of bifidobacterium animalis subsp. lactis was analyzed, and an intracellular endopeptidase (pepo) was identified and characterized. this work reports the first complete cloning, purification, and characterization of a proteolytic enzyme in bifidobacterium spp. aminopeptidase activities (general aminopeptidases, proline iminopeptidase, x-prolyl dipeptidylaminopeptidase) found in cell extracts of b. animalis subsp. lactis were higher for cells that had been grown in a milk-b ... | 2005 | 16332835 |
| antibiotic susceptibility patterns and resistance genes of starter cultures and probiotic bacteria used in food. | a survey of starter and probiotic cultures was carried out to determine the current antibiotic resistance situation in microbial food additives in switzerland. two hundred isolates from 90 different sources were typed by molecular and other methods to belong to the genera lactobacillus (74 samples), staphylococcus (33 samples), bifidobacterium (6 samples), pediococcus (5 samples), or were categorized as lactococci or streptococci (82 samples). they were screened for phenotypic resistances to 20 ... | 2006 | 16464696 |
| transcriptional and functional analysis of oxalyl-coenzyme a (coa) decarboxylase and formyl-coa transferase genes from lactobacillus acidophilus. | oxalic acid is found in dietary sources (such as coffee, tea, and chocolate) or is produced by the intestinal microflora from metabolic precursors, like ascorbic acid. in the human intestine, oxalate may combine with calcium, sodium, magnesium, or potassium to form less soluble salts, which can cause pathological disorders such as hyperoxaluria, urolithiasis, and renal failure in humans. in this study, an operon containing genes homologous to a formyl coenzyme a transferase gene (frc) and an oxa ... | 2006 | 16517636 |
| carbohydrate preference, acid tolerance and bile tolerance in five strains of bifidobacterium. | to assess the suitability of bifidobacteria for inclusion in synbiotic products on the basis of carbohydrate preference, acid and bile tolerance. | 2006 | 16553741 |
| probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with lactobacillus acidophilus and bifidobacterium animalis subsp. lactis. | probiotic treatment may be effective in diseases involving gut microflora and intestinal inflammation. in collagenous colitis (cc), a potential pathogenic role of the gut microflora has been proposed. the effect of probiotic treatment in cc is unknown. our aim was to investigate the clinical effect of treatment with lactobacillus acidophilus la-5 and bifidobacterium animalis subsp. lactis bb-12 (ab-cap-10) in patients with cc. | 2006 | 16670529 |
| antagonistic activity of probiotic lactobacilli and bifidobacteria against entero- and uropathogens. | to develop in vitro assays for comparing the antagonistic properties and anti-oxidative activity of probiotic lactobacillus and bifidobacterium strains against various entero- and urinary pathogens. | 2006 | 16696680 |
| antimicrobial susceptibility of bifidobacterium strains from humans, animals and probiotic products. | the aim of this study was to assess the antimicrobial susceptibility of a taxonomically diverse set of bifidobacterium strains to different classes of antimicrobial agents using a recently described medium. | 2006 | 16698847 |
| dose-response study of probiotic bacteria bifidobacterium animalis subsp lactis bb-12 and lactobacillus paracasei subsp paracasei crl-341 in healthy young adults. | this study was performed to investigate the dose-response effects of supplementation with bifidobacterium animalis subsp lactis (bb-12) and lactobacillus paracasei subsp paracasei (crl-431) on blood lipids, recovery from feces and bowel habits. changes of the fecal microflora was analyzed in the 10(10) cfu/day probiotic and placebo group. | 2006 | 16721394 |
| short communication: effect of exopolysaccharide isolated from "viili" on the adhesion of probiotics and pathogens to intestinal mucus. | the strong ropy character of the scandinavian fermented milk viili is conferred by the exopolysaccharides (eps) produced by lactococcal strains. these biopolymers can be responsible for some health benefits. we have assessed the influence of the eps fraction isolated from commercial viili on the adhesion of some probiotics and pathogens to human intestinal mucus. concentrations of viili eps greater than 0.1 mg/ml promoted a decrease in adherence of bifidobacterium lactis bb12 and lactobacillus r ... | 2006 | 16772550 |
| anti-inflammatory metabolite production in the gut from the consumption of probiotic yogurt containing bifidobacterium animalis subsp. lactis lkm512. | there is little evidence for a relationship between probiotic metabolites and host cytokine production. we investigated in the present study the possibility that anti-inflammatory metabolites can be produced in the gut by lkm512 yogurt consumption by using murine macrophage-like j774.1 cells and extracts prepared from the feces of elderly volunteers. these volunteers' acute inflammation had been inhibited by lkm512 yogurt consumption in a previous test. the tumor necrosis factor (tnf)-alpha prod ... | 2006 | 16794305 |
| bifidobacterium lactis bb-12 and lactobacillus salivarius ucc500 modify carboxylic acid formation in the hindgut of rats given pectin, inulin, and lactitol. | the effect of bifidobacterium lactis (bb-12) and lactobacillus salivarius (ucc500) on the formation of carboxylic acids (cas) was studied in the hindgut of rats fed pectin, inulin of low solubility, and lactitol. when the pectin diet was supplemented with bb-12, the formation of cas was larger throughout the colon of rats, due to increased formation of acetic acid (p < 0.01) and, in the distal part of the colon, also because of propionic and butyric acids (p < 0.01). in rats fed pectin and ucc50 ... | 2006 | 16857837 |